List of works - Babette Weksler

A multi-system approach assessing the interaction of anticonvulsants with P-gp

scientific article

Abnormal megakaryopoiesis and platelet function in cyclooxygenase-2-deficient mice

scientific article

Adenosine receptors regulate gap junction coupling of the human cerebral microvascular endothelial cells hCMEC/D3 by Ca2+ influx through cyclic nucleotide-gated channels

scientific article published on 11 January 2017

Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFP spontaneously cross the blood-brain barrier and specifically recognize astrocytes: application to brain imaging

scientific article

Cyclooxygenase-2–Derived Prostacyclin Regulates Arterial Thrombus Formation by Suppressing Tissue Factor in a Sirtuin-1–Dependent-Manner

scientific article published on 03 August 2012

Cytokines present in smokers' serum interact with smoke components to enhance endothelial dysfunction

scientific article published on February 2011

Development of a three-dimensional, all-human in vitro model of the blood-brain barrier using mono-, co-, and tri-cultivation Transwell models

scientific article published on 14 May 2011

Differential effects of hydrocortisone and TNFalpha on tight junction proteins in an in vitro model of the human blood-brain barrier

scientific article published on 7 February 2008

Differential permissivity of human cerebrovascular endothelial cells to enterovirus infection and specificities of serotype EV-A71 in crossing an in vitro model of the human blood-brain barrier

scientific article

Drug-induced trafficking of p-glycoprotein in human brain capillary endothelial cells as demonstrated by exposure to mitomycin C

scientific article (publication date: 2014)

Effect of cigarette smoke on monocyte procoagulant activity: Focus on platelet-derived brain-derived neurotrophic factor (BDNF).

scientific article

Evaluation of soluble junctional adhesion molecule-A as a biomarker of human brain endothelial barrier breakdown

scientific article

Expression and localization of claudins-3 and -12 in transformed human brain endothelium

scientific article

Expression of ADAM-17, TIMP-3 and fractalkine in the human adult brain endothelial cell line, hCMEC/D3, following pro-inflammatory cytokine treatment

scientific article published on 25 March 2009

Hepatitis C virus infects the endothelial cells of the blood-brain barrier

scientific article published on December 2011

Hyperosmotic stress induces Axl activation and cleavage in cerebral endothelial cells

scientific article

Identification of peptide ligands for targeting to the blood-brain barrier

scientific article

Immortalized human brain endothelial cells and flow-based vascular modeling: a marriage of convenience for rational neurovascular studies

scientific article

Immortalized human cerebral microvascular endothelial cells maintain the properties of primary cells in an in vitro model of immune migration across the blood brain barrier

scientific article published on 13 October 2012

Lamotrigine is a substrate for OCT1 in brain endothelial cells

scientific article published on 29 December 2011

Modulation of blood-brain barrier permeability by neutrophils: in vitro and in vivo studies

scientific article

Paracrine signalling of inflammatory cytokines from an in vitro blood brain barrier model upon exposure to polymeric nanoparticles

scientific article published on 5 November 2013

Peripheral blood CD4+ T lymphocytes from multiple sclerosis patients are characterized by higher PSGL-1 expression and transmigration capacity across a human blood-brain barrier-derived endothelial cell line

scientific article

Pivotal Role for CD16+ Monocytes in Immune Surveillance of the Central Nervous System

scientific article published on 8 January 2016

Production of prostaglandin E2 induced by cigarette smoke modulates tissue factor expression and activity in endothelial cells

scientific article published on 11 June 2015

Purine receptors and Ca(2+) signalling in the human blood-brain barrier endothelial cell line hCMEC/D3

scientific article published on 29 September 2011

Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling

scientific article

Role of KCNMA1 gene in breast cancer invasion and metastasis to brain

scientific article published on 29 July 2009

Somatostatin preserved blood brain barrier against cytokine induced alterations: possible role in multiple sclerosis

scientific article published on 13 June 2013

Suppressing PTEN activity by tobacco smoke plus interleukin-1beta modulates dissociation of VE-cadherin/beta-catenin complexes in endothelium

scientific article

Temporal profile of matrix metalloproteinases and their inhibitors in a human endothelial cell culture model of cerebral ischemia

scientific article published on 25 June 2013

The hCMEC/D3 cell line as a model of the human blood brain barrier

scientific article published on 26 March 2013

The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies

scientific article

The involvement of a Na⁺- and Cl⁻-dependent transporter in the brain uptake of amantadine and rimantadine

scientific article published in March 2012

The poorly membrane permeable antipsychotic drugs amisulpride and sulpiride are substrates of the organic cation transporters from the SLC22 family

scientific article published on 26 August 2014

Tobacco smoke regulates the expression and activity of microsomal prostaglandin E synthase-1: role of prostacyclin and NADPH-oxidase

scientific article published on 7 July 2011

Transcellular targeting of fiber- and hexon-modified adenovirus vectors across the brain microvascular endothelial cells in vitro

scientific article

Transthyretin participates in beta-amyloid transport from the brain to the liver--involvement of the low-density lipoprotein receptor-related protein 1?

scientific article published on 3 February 2016

Uptake and permeability studies of BBB-targeting immunoliposomes using the hCMEC/D3 cell line

scientific article published on 29 November 2010

List of works by Babette Weksler

A multi-system approach assessing the interaction of anticonvulsants with P-gp

Abnormal megakaryopoiesis and platelet function in cyclooxygenase-2-deficient mice

Adenosine receptors regulate gap junction coupling of the human cerebral microvascular endothelial cells hCMEC/D3 by Ca2+ influx through cyclic nucleotide-gated channels

Cell-penetrating anti-GFAP VHH and corresponding fluorescent fusion protein VHH-GFP spontaneously cross the blood-brain barrier and specifically recognize astrocytes: application to brain imaging

Cyclooxygenase-2–Derived Prostacyclin Regulates Arterial Thrombus Formation by Suppressing Tissue Factor in a Sirtuin-1–Dependent-Manner

Cytokines present in smokers' serum interact with smoke components to enhance endothelial dysfunction

Development of a three-dimensional, all-human in vitro model of the blood-brain barrier using mono-, co-, and tri-cultivation Transwell models

Differential effects of hydrocortisone and TNFalpha on tight junction proteins in an in vitro model of the human blood-brain barrier

Differential permissivity of human cerebrovascular endothelial cells to enterovirus infection and specificities of serotype EV-A71 in crossing an in vitro model of the human blood-brain barrier

Drug-induced trafficking of p-glycoprotein in human brain capillary endothelial cells as demonstrated by exposure to mitomycin C

Effect of cigarette smoke on monocyte procoagulant activity: Focus on platelet-derived brain-derived neurotrophic factor (BDNF).

Evaluation of soluble junctional adhesion molecule-A as a biomarker of human brain endothelial barrier breakdown

Expression and localization of claudins-3 and -12 in transformed human brain endothelium

Expression of ADAM-17, TIMP-3 and fractalkine in the human adult brain endothelial cell line, hCMEC/D3, following pro-inflammatory cytokine treatment

Hepatitis C virus infects the endothelial cells of the blood-brain barrier

Hyperosmotic stress induces Axl activation and cleavage in cerebral endothelial cells

Identification of peptide ligands for targeting to the blood-brain barrier

Immortalized human brain endothelial cells and flow-based vascular modeling: a marriage of convenience for rational neurovascular studies

Immortalized human cerebral microvascular endothelial cells maintain the properties of primary cells in an in vitro model of immune migration across the blood brain barrier

Lamotrigine is a substrate for OCT1 in brain endothelial cells

Modulation of blood-brain barrier permeability by neutrophils: in vitro and in vivo studies

Paracrine signalling of inflammatory cytokines from an in vitro blood brain barrier model upon exposure to polymeric nanoparticles

Peripheral blood CD4+ T lymphocytes from multiple sclerosis patients are characterized by higher PSGL-1 expression and transmigration capacity across a human blood-brain barrier-derived endothelial cell line

Pivotal Role for CD16+ Monocytes in Immune Surveillance of the Central Nervous System

Production of prostaglandin E2 induced by cigarette smoke modulates tissue factor expression and activity in endothelial cells

Purine receptors and Ca(2+) signalling in the human blood-brain barrier endothelial cell line hCMEC/D3

Reactive oxygen species alter brain endothelial tight junction dynamics via RhoA, PI3 kinase, and PKB signaling

Role of KCNMA1 gene in breast cancer invasion and metastasis to brain

Somatostatin preserved blood brain barrier against cytokine induced alterations: possible role in multiple sclerosis

Suppressing PTEN activity by tobacco smoke plus interleukin-1beta modulates dissociation of VE-cadherin/beta-catenin complexes in endothelium

Temporal profile of matrix metalloproteinases and their inhibitors in a human endothelial cell culture model of cerebral ischemia

The hCMEC/D3 cell line as a model of the human blood brain barrier

The human brain endothelial cell line hCMEC/D3 as a human blood-brain barrier model for drug transport studies

The involvement of a Na⁺- and Cl⁻-dependent transporter in the brain uptake of amantadine and rimantadine

The poorly membrane permeable antipsychotic drugs amisulpride and sulpiride are substrates of the organic cation transporters from the SLC22 family

Tobacco smoke regulates the expression and activity of microsomal prostaglandin E synthase-1: role of prostacyclin and NADPH-oxidase

Transcellular targeting of fiber- and hexon-modified adenovirus vectors across the brain microvascular endothelial cells in vitro

Transthyretin participates in beta-amyloid transport from the brain to the liver--involvement of the low-density lipoprotein receptor-related protein 1?

Uptake and permeability studies of BBB-targeting immunoliposomes using the hCMEC/D3 cell line