List of works by Michael Eccles

A Guide for Designing and Analyzing RNA-Seq Data

scientific article published on 01 January 2018

A cross comparison of technologies for the detection of microRNAs in clinical FFPE samples of hepatoblastoma patients

scientific article published on 3 June 2015

A gene expression signature of invasive potential in metastatic melanoma cells

scientific article

A streamlined method for analysing genome-wide DNA methylation patterns from low amounts of FFPE DNA.

scientific article

Abstract 826: Global DNA methylation levels regulate PD-L1 expression in melanoma

scholarly article

An ovine hepatorenal fibrocystic model of a Meckel-like syndrome associated with dysmorphic primary cilia and TMEM67 mutations

scientific article

Application of circularly polarized light for non-invasive diagnosis of cancerous tissues and turbid tissue-like scattering media

scientific article

Bridging Small Molecules to Modified Bacterial Microparticles Using a Disulphide Linkage: MIS416 as a Cargo Delivery System

scientific article published on 22 December 2015

Characterisation of DNA methylation changes in EBF3 and TBC1D16 associated with tumour progression and metastasis in multiple cancer types

scientific article published on 05 August 2019

Chemical Synthesis of the PAX Protein Inhibitor EG1 and Its Ability to Slow the Growth of Human Colorectal Carcinoma Cells

scientific article published on 13 October 2021

Chromosomal ocations fo the genes coding for the integrin ?6 and ?7 subunits

scientific article (publication date: 1992)

Clinical utility gene card for: renal coloboma (Papillorenal) syndrome

scientific article published on 16 February 2011

Cohesin is required for activation of MYC by estradiol

scientific article

Comparative assessment of DNA methylation patterns between reduced representation bisulfite sequencing and Sequenom EpiTyper methylation analysis.

scientific article published on 19 May 2017

DNA methylation and epigenomics: new technologies and emerging concepts.

scientific article published on 21 May 2015

Designing phantoms to accurately replicate circular depolarization in biological scattering media

scientific article published on 01 December 2019

Differential Expression of BARD1 Isoforms in Melanoma

EZH2 cooperates with DNA methylation to downregulate key tumour suppressors and interferon gene signatures in melanoma

scientific article published on 29 April 2020

Epigenetic drivers of tumourigenesis and cancer metastasis

scientific article published on 11 August 2017

Erratum: A cross comparison of technologies for the detection of microRNAs in clinical FFPE samples of hepatoblastoma patients

scientific article published on 2 September 2015

Expression of cohesin and condensin genes during zebrafish development supports a non-proliferative role for cohesin

scientific article published on 31 August 2009

Extensive Inter-Cyst DNA Methylation Variation in Autosomal Dominant Polycystic Kidney Disease Revealed by Genome Scale Sequencing

scientific article published on 15 April 2020

Genetic and Genomic Pathways of Melanoma Development, Invasion and Metastasis

scientific article published on 29 September 2021

Genome-Scale Single Nucleotide Resolution Analysis of DNA Methylation in Human Autosomal Dominant Polycystic Kidney Disease

scientific article published on 21 November 2018

Genome-wide methylation sequencing of paired primary and metastatic cell lines identifies common DNA methylation changes and a role for EBF3 as a candidate epigenetic driver of melanoma metastasis

scientific article published on 20 December 2016

Genome-wide miRNA methylome analysis in oral cancer: possible biomarkers associated with patient survival

scientific article published on 15 March 2019

Genomic and signalling pathway characterisation of the NZM panel of melanoma cell lines: a valuable model for studying the impact of genetic diversity in melanoma

scientific article published on 22 June 2020

Identification of the first AHI1 gene mutations in nephronophthisis-associated Joubert syndrome

scientific article

In vivo validation of PAX2 as a target for renal cancer therapy

scientific article

Increased paired box transcription factor 8 has a survival function in glioma

scientific article

Large animal models of rare genetic disorders: sheep as phenotypically relevant models of human genetic disease

scientific article

Lipid and Polymer-Based Nanoparticle siRNA Delivery Systems for Cancer Therapy

scientific article published on 10 June 2020

MIS416 as a siRNA Delivery System with the Ability to Target Antigen-Presenting Cells

scholarly article by Francesco Mainini published in August 2018

MITF and PAX3 Play Distinct Roles in Melanoma Cell Migration; Outline of a "Genetic Switch" Theory Involving MITF and PAX3 in Proliferative and Invasive Phenotypes of Melanoma

scientific article

Marked Global DNA Hypomethylation Is Associated with Constitutive PD-L1 Expression in Melanoma

scientific article published on 28 June 2018

MicroRNA expression patterns and signalling pathways in the development and progression of childhood solid tumours.

scientific article published on 19 January 2017

Multi-platform microRNA profiling of hepatoblastoma patients using formalin fixed paraffin embedded archival samples.

scientific article

NRAS and EPHB6 mutation rates differ in metastatic melanomas of patients in the North Island versus South Island of New Zealand.

scientific article published on 13 May 2016

Neuronal apoptosis inhibitory protein is expressed in developing kidney and is regulated by PAX2

scientific article

PAX genes in development and disease: the role of PAX2 in urogenital tract development

scientific article

PAX2 activates WNT4 expression during mammalian kidney development

scientific article

PAX3 Is extensively expressed in benign and malignant tissues of the melanocytic lineage in humans

scientific article published on 28 January 2010

PAX3 is expressed in the stromal compartment of the developing kidney and in Wilms tumors with myogenic phenotype

scientific article

PAX3 knockdown in metastatic melanoma cell lines does not reduce MITF expression

scientific article published on February 2011

PAX8 regulates telomerase reverse transcriptase and telomerase RNA component in glioma

scientific article

Paired-Box genes are frequently expressed in cancer and often required for cancer cell survival

scientific article

Pax2 gene dosage influences cystogenesis in autosomal dominant polycystic kidney disease.

scientific article published on 2 November 2006

Polycystic kidney disease - where gene dosage counts

scientific article

Rapamycin-mediated suppression of renal cyst expansion in del34 Pkd1-/- mutant mouse embryos: an investigation of the feasibility of renal cyst prevention in the foetus.

scientific article published on November 2012

Reawakening the Developmental Origins of Cancer Through Transposable Elements

scientific article published on 05 May 2020

Repression of CMIP transcription by WT1 is relevant to podocyte health

scientific article published on 17 September 2016

Rescue of defective branching nephrogenesis in renal-coloboma syndrome by the caspase inhibitor, Z-VAD-fmk

scientific article published on February 2004

SMAD proteins directly suppress PAX2 transcription downstream of transforming growth factor-beta 1 (TGF-β1) signalling in renal cell carcinoma.

scientific article published in June 2018

Somatic reactivation of expression of the silent maternal Mest allele and acquisition of normal reproductive behaviour in a colony of Peg1/Mest mutant mice

scientific article published on 21 April 2012

Suppression of ureteric bud apoptosis rescues nephron endowment and adult renal function in Pax2 mutant mice

scientific journal article

Targeted Therapies for Autosomal Dominant Polycystic Kidney Disease

scientific article published on 01 January 2019

Targeted therapy; from advanced melanoma to the adjuvant setting

scientific article published on 9 August 2013

Targeting DNA Methylation and EZH2 Activity to Overcome Melanoma Resistance to Immunotherapy

scientific article published on 07 March 2019

The Genes of Life and Death: A Potential Role for Placental-Specific Genes in Cancer: Active retrotransposons in the placenta encode unique functional genes that may also be used by cancer cells to promote malignancy

scientific article published on 4 October 2017

The Slow Cycling Phenotype: A Growing Problem for Treatment Resistance in Melanoma.

scientific article published on June 2017

Tools and Strategies for Analysis of Genome-Wide and Gene-Specific DNA Methylation Patterns

scientific article published on January 2017

Tuberous sclerosis complex: a complex case

scientific article published on 28 April 2022

Update of PAX2 mutations in renal coloboma syndrome and establishment of a locus-specific database.

scientific article published on 31 January 2012

Ureteric Bud Apoptosis and Renal Hypoplasia in Transgenic PAX2-Bax Fetal Mice Mimics the Renal-Coloboma Syndrome ⬇️

scientific article published on November 1, 2003

WT1 is a modifier of the Pax2 mutant phenotype: cooperation and interaction between WT1 and Pax2 ⬇️

scientific article published on November 6, 2003

scan_tcga tools for integrated epigenomic and transcriptomic analysis of tumor subgroups

scientific article

Paulina is supported by:

About Paulina

Help