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List of works by Ross L Levine

A JAK2/IDH1-mutant MPN clone unmasked by ivosidenib in an AML patient without antecedent MPN

scientific article published on 01 December 2020

A Mathematical Methodology for Determining the Temporal Order of Pathway Alterations Arising during Gliomagenesis ⬇️

scientific article published on January 5, 2012

A germline JAK2 SNP is associated with predisposition to the development of JAK2(V617F)-positive myeloproliferative neoplasms

scientific article

A recurrent germline PAX5 mutation confers susceptibility to pre-B cell acute lymphoblastic leukemia

scientific article

COVID-19 impact on early career investigators: a call for action

scientific article published on 05 June 2020

CXCL8/CXCR2 signaling mediates bone marrow fibrosis and is a therapeutic target in myelofibrosis

scientific article published on 18 May 2023

Cancer therapy shapes the fitness landscape of clonal hematopoiesis

scientific article published on 26 October 2020

Clinical effect of point mutations in myelodysplastic syndromes

scientific article

Clonal Hematopoiesis and Evolution to Hematopoietic Malignancies

scientific article published in February 2018

Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation

scientific article published on 05 September 2019

Concomitant analysis of EZH2 and ASXL1 mutations in myelofibrosis, chronic myelomonocytic leukemia and blast-phase myeloproliferative neoplasms ⬇️

scientific article published on April 1, 2011

DNMT3A and stem cell function: new insights into old pathways ⬇️

scientific article published on March 1, 2012

DNMT3A mutational analysis in primary myelofibrosis, chronic myelomonocytic leukemia and advanced phases of myeloproliferative neoplasms ⬇️

scientific article published on April 26, 2011

Do circulating tumor cells play a role in coagulation and thrombosis? ⬇️

scientific article published on September 10, 2012

Epigenetic Identity in AML Depends on Disruption of Nonpromoter Regulatory Elements and Is Affected by Antagonistic Effects of Mutations in Epigenetic Modifiers.

scientific article published on 13 April 2017

Evaluating Clonal Hematopoiesis in Tumor-Infiltrating Leukocytes in Breast Cancer and Secondary Hematologic Malignancies

scientific article published on 01 January 2020

Finding a needle in a haystack: whole genome sequencing and mutation discovery in murine models ⬇️

scientific article published on March 23, 2011

Genetic analysis of patients with leukemic transformation of myeloproliferative neoplasms shows recurrent SRSF2 mutations that are associated with adverse outcome

scientific article

Genetic analysis of transforming events that convert chronic myeloproliferative neoplasms to leukemias

scientific article

Genetic and epigenetic evolution as a contributor to WT1-mutant leukemogenesis

scientific article published on 31 July 2018

Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies

scientific article

Genetic resistance to JAK2 enzymatic inhibitors is overcome by HSP90 inhibition ⬇️

scientific article published on January 23, 2012

High-throughput sequence analysis of the tyrosine kinome in acute myeloid leukemia

scientific article published on 5 February 2008

High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients

scientific article published on 15 December 2008

IDH1 Mutations Disrupt Blood, Brain, and Barriers ⬇️

scientific article published on September 11, 2012

Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production ⬇️

scientific article published on September 26, 2011

In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs

scientific article published on 23 July 2015

JAK2 inhibition sensitizes resistant EGFR-mutant lung adenocarcinoma to tyrosine kinase inhibitors

scientific article published on 29 March 2016

JAK2 the future: therapeutic strategies for JAK-dependent malignancies ⬇️

scientific article published on September 17, 2012

Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis.

scientific article published on 20 September 2017

Jak1 Integrates Cytokine Sensing to Regulate Hematopoietic Stem Cell Function and Stress Hematopoiesis.

scientific article published in February 2018

Leveraging Cancer Genome Information in Hematologic Malignancies ⬇️

scientific article published on April 15, 2013

MEN1 mutations mediate clinical resistance to menin inhibition

scientific article published on 15 March 2023

Molecular analysis of patients with polycythemia vera or essential thrombocythemia receiving pegylated interferon α-2a

scientific article published on 19 June 2013

Mutational analysis of therapy-related myelodysplastic syndromes and acute myelogenous leukemia ⬇️

scientific article published on January 24, 2013

NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases ⬇️

scientific article published on November 12, 2010

New pieces of a puzzle: The current biological picture of MPN ⬇️

scientific article published on July 20, 2012

Novel MEK1 mutation identified by mutational analysis of epidermal growth factor receptor signaling pathway genes in lung adenocarcinoma

scientific article published on July 2008

Oncogenic signals as treatment targets in classic myeloproliferative neoplasms

scientific article published on January 2009

PRMT5 inhibition modulates E2F1 methylation and gene regulatory networks leading to therapeutic efficacy in JAK2V617F mutant MPN

scientific article published on 15 July 2020

Plasmacytoid dendritic cell expansion defines a distinct subset of RUNX1 mutated acute myeloid leukemia

scientific article published on 01 September 2020

Precision medicine treatment in acute myeloid leukemia using prospective genomic profiling: feasibility and preliminary efficacy of the Beat AML Master Trial

scientific article published on 26 October 2020

Primary myelofibrosis (PMF), post polycythemia vera myelofibrosis (post-PV MF), post essential thrombocythemia myelofibrosis (post-ET MF), blast phase PMF (PMF-BP): Consensus on terminology by the international working group for myelofibrosis resear

scientific article published on 8 January 2007

Sensitivity and resistance of JAK2 inhibitors to myeloproliferative neoplasms ⬇️

scientific article published on May 14, 2013

Sequential azacitidine plus lenalidomide combination for elderly patients with untreated acute myeloid leukemia ⬇️

scientific article published on December 14, 2012

Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia ⬇️

scientific article published on 02 May 2013

Single-cell mutation analysis of clonal evolution in myeloid malignancies

scientific article published on 28 October 2020

Smc3 dosage regulates B cell transit through germinal centers and restricts their malignant transformation

scientific article published on 11 January 2021

TET2 in Normal and Malignant Hematopoiesis

scientific article published on 27 February 2017

TYK2-STAT1-BCL2 pathway dependence in T-cell acute lymphoblastic leukemia

scientific article published on 7 March 2013

Targeted Immunotherapy for Hairy Cell Leukemia ⬇️

scientific article published on February 21, 2012

Targeting β-catenin in CML: Leukemia Stem Cells Beware! ⬇️

scientific article published on 01 April 2012

The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis

scientific article published on 17 March 2021

The Notch/Hes1 pathway sustains NF-κB activation through CYLD repression in T cell leukemia.

scientific article

The landscape of somatic copy-number alteration across human cancers

scientific article

Unraveling the Molecular Pathophysiology of Myelodysplastic Syndromes ⬇️

scientific article published on January 10, 2011

Validation of a prognostic model and the impact of mutations in patients with lower-risk myelodysplastic syndromes

scientific article

Vascular endothelial growth factor expression in acute myeloid leukemia: a biomarker ready for primetime? ⬇️

scientific article published on 05 March 2013

miR-433 is aberrantly expressed in myeloproliferative neoplasms and suppresses hematopoietic cell growth and differentiation ⬇️

scientific article published on August 6, 2012

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