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List of works by Wenfeng Fang

A Patient with EGFR Exon 20 Insertion-Mutant Non-Small Cell Lung Cancer Responded to Osimertinib plus Cetuximab Combination Therapy

scientific article published on 01 September 2019

A Phase I Dose Escalation Study of the Safety, Tolerability, and Pharmacokinetics of Ipilimumab in Chinese Patients with Select Advanced Solid Tumors

scientific article published on 26 October 2020

A Phase I/II Open-Label Study of Nivolumab in Previously Treated Advanced or Recurrent Nasopharyngeal Carcinoma and Other Solid Tumors

scientific article published on 02 May 2019

A large, single-center, real-world study of clinicopathological characteristics and treatment in advanced ALK-positive non-small-cell lung cancer

scientific article

A large-scale cross-sectional study of ALK rearrangements and EGFR mutations in non-small-cell lung cancer in Chinese Han population

scientific article

A multicenter, retrospective epidemiologic survey of the clinical features and management of bone metastatic disease in China

scientific article published on 25 April 2016

A novel tumor mutational burden estimation model as a predictive and prognostic biomarker in NSCLC patients

scientific article published on 26 August 2020

A retrospective analysis of efficacy and safety of adding bevacizumab to chemotherapy as first- and second-line therapy in advanced non-small-cell lung cancer (NSCLC).

scientific article

A systemic inflammation-based prognostic scores (mGPS) predicts overall survival of patients with small-cell lung cancer

scientific article published on 26 September 2014

Abstract 327: The impact of PIK3CA/PTEN/AKT1 genes in advanced NSCLC patients with acquired EGFR-TKI resistance and clinical response to EGFR-TKI plus everolimus combination therapy

scholarly article

Acquired EGFR L718V Mutation and Loss of T790M-Mediated Resistance to Osimertinib in a Patient With NSCLC Who Responded to Afatinib

scientific article published on 01 December 2019

Advanced Lung Cancer Inflammation Index, a New Prognostic Score, Predicts Outcome in Patients With Small-Cell Lung Cancer

scientific article published on 26 March 2015

An investigation of symptom burden and quality of life in Chinese chemo-naïve advanced lung cancer patients by using the Instrument-Cloud QOL System

scientific article published on 7 February 2014

Anti-epidermal growth factor receptor monoclonal antibody plus palliative chemotherapy as a first-line treatment for recurrent or metastatic nasopharyngeal carcinoma

scientific article published on 19 January 2020

Anticancer drug R&D landscape in China

scientific article published on 13 May 2020

Association between PD-L1 Expression on Tumour-Infiltrating Lymphocytes and Overall Survival in Patients with Gastric Cancer

scientific article published on 03 June 2017

Camrelizumab (SHR-1210) alone or in combination with gemcitabine plus cisplatin for nasopharyngeal carcinoma: results from two single-arm, phase 1 trials

scientific article published on 10 September 2018

Cause-specific death assessment of patients with stage I small-cell lung cancer: a competing risk analysis

scientific article published on 26 June 2019

Clinical pharmacokinetics and drug exposure-toxicity correlation study of docetaxel based chemotherapy in Chinese head and neck cancer patients

scientific article published on 01 March 2020

Co-expression of PD-1 and PD-L1 predicts poor outcome in nasopharyngeal carcinoma.

scientific article

Combinatorial assessment of ctDNA release and mutational burden predicts anti-PD(L)1 therapy outcome in nonsmall-cell lung cancer

scientific article published on 01 January 2020

Combined Model of Frameshift Mutations and Tumor Mutation Burden in Predicting Preliminary Response to Immune Checkpoint Inhibitors in NSCLC

scientific article published on 01 December 2019

Concomitant Genetic Alterations With Response to Treatment and Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Patients With EGFR-Mutant Advanced Non-Small Cell Lung Cancer

scientific article published on 29 March 2018

Conformational Landscapes of HER2 Exon 20 Insertions Explain Their Sensitivity to Kinase Inhibitors in Lung Adenocarcinoma

scientific article published on 07 February 2020

Correction to: Pharmacokinetic and Pharmacodynamic Analyses of 5-Fluorouracil in East-Asian Patients with Nasopharyngeal Carcinoma

scientific article published on 26 December 2017

Correction: Overexpression of wildtype EGFR is tumorigenic and denotes a therapeutic target in non-small cell lung cancer

Docosapentaenoic acid and lung cancer risk: A Mendelian randomization study

scientific article published on 11 February 2019

Dual blockade of EGFR and VEGFR pathways: Results from a pilot study evaluating apatinib plus gefitinib as a first-line treatment for advanced EGFR-mutant non-small cell lung cancer

scientific article published on 04 June 2020

Durable Response of Low-Dose Afatinib plus Cetuximab in an Adenocarcinoma Patient with a Novel EGFR Exon 20 Insertion Mutation

scientific article published on 01 October 2019

EBV-driven LMP1 and IFN-γ up-regulate PD-L1 in nasopharyngeal carcinoma: Implications for oncotargeted therapy

scientific article

EGFR T790M relative mutation purity predicts osimertinib treatment efficacy in non-small cell lung cancer patients

scientific article published on 17 February 2020

EGFR exon 20 insertion mutations and response to osimertinib in non-small-cell lung cancer.

scientific article published on 17 June 2019

EGFR mutation genotypes affect efficacy and resistance mechanisms of osimertinib in T790M-positive NSCLC patients

scientific article published on 01 June 2020

EPHA mutation as a predictor of immunotherapeutic efficacy in lung adenocarcinoma

scientific article published on 01 December 2020

Education and lung cancer: a Mendelian randomization study

scientific article published on 01 June 2019

Efficacy and Tolerability of Erlotinib 100 mg/d vs. Gefitinib 250 mg/d in EGFR-Mutated Advanced Non-small Cell Lung Cancer (E100VG250): An Open-Label, Randomized, Phase 2 Study

scientific article published on 10 November 2020

Efficacy of BIBF 1120 or BIBF 1120 plus chemotherapy on nasopharyngeal carcinoma in vitro and in vivo

scientific article published on 15 March 2016

Efficacy of Immune Checkpoint Inhibitors in SMARCA4-Mutant NSCLC

scientific article published on 01 August 2020

Efficacy of epidermal growth factor receptor-tyrosine kinase inhibitors for Chinese patients with squamous cell carcinoma of lung harboring EGFR mutation

scientific article published on October 2013

Emergence of EGFR G724S After Progression on Osimertinib Responded to Afatinib Monotherapy

scientific article published on 01 March 2020

Erratum: Expression of programmed death ligand-1 on tumor cells varies pre and post chemotherapy in non-small cell lung cancer

scientific article

Establishment and application of a predictive model for gefitinib-induced severe rash based on pharmacometabolomic profiling and polymorphisms of transporters in non-small cell lung cancer

scientific article published on 19 November 2020

Expression of programmed death ligand-1 on tumor cells varies pre and post chemotherapy in non-small cell lung cancer

scientific article published on 29 January 2016

First-in-Human Phase I Study of AC0010, a Mutant-Selective EGFR Inhibitor in Non-Small Cell Lung Cancer: Safety, Efficacy, and Potential Mechanism of Resistance

scientific article published on 4 April 2018

Genetic basis of PD-L1 overexpression in diffuse large B-cell lymphomas

scientific article published on 30 March 2016

Genomic Analysis of Nasopharyngeal Carcinoma Reveals TME-based Subtypes

scientific article published on 29 August 2017

Identification of a Novel KIF5B-RET, ABHD17C-RET Double-Fusion Variant in Lung Adenocarcinoma and Response to Cabozantinib

scientific article published on 01 August 2020

Immune-related pneumonitis associated with immune checkpoint inhibitors in lung cancer: a network meta-analysis

scientific article published on 01 August 2020

Impact of Smoking Status on the Efficacy of Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors Plus Anti-Vascular Endothelial Growth Factor Antibodies in Non-Small Cell Lung Cancer: A Systematic Review and Meta-Analysis

scientific article published in 2022

Impact of gefitinib in early stage treatment on circulating cytokines and lymphocytes for patients with advanced non-small cell lung cancer

scientific article published on 21 February 2017

Impact of prior cancer history on the overall survival of patients newly diagnosed with cancer: A pan-cancer analysis of the SEER database

scientific article published on 07 May 2018

Impact of prior cancer on outcomes in nasopharyngeal carcinoma

scientific article published on 01 July 2019

Impact of smoking status on EGFR-TKI efficacy for advanced non-small-cell lung cancer in EGFR mutants: a meta-analysis

scientific article published on 2 October 2014

In vitro and in vivo efficacy of afatinib as a single agent or in combination with gemcitabine for the treatment of nasopharyngeal carcinoma

scientific article published on 31 March 2016

Intratumor heterogeneity comparison among different subtypes of non-small-cell lung cancer through multi-region tissue and matched ctDNA sequencing

scholarly article by Yaxiong Zhang et al published 9 January 2019 in Molecular Cancer

KEYNOTE-032: A Randomized Phase I Study of Pembrolizumab in Chinese Patients with Advanced Non-Small-Cell Lung Cancer

scientific article published on 05 March 2020

KRAS mutation-induced upregulation of PD-L1 mediates immune escape in human lung adenocarcinoma

scientific article published on 27 April 2017

MPRIP-ALK, a Novel ALK Rearrangement That Responds to ALK Inhibition in NSCLC

scientific article published on 01 July 2019

Mendelian randomization study showed no causality between metformin use and lung cancer risk

scientific article published on 19 October 2019

Multi-targeted antiangiogenic tyrosine kinase inhibitors in advanced non-small cell lung cancer: meta-analyses of 20 randomized controlled trials and subgroup analyses

scientific article

Multi-targeted tyrosine kinase inhibitors as third-line regimen in advanced non-small cell lung cancer: a network meta-analysis

scientific article published on 01 September 2019

Mutation Variants and Co-Mutations as Genomic Modifiers of Response to Afatinib in HER2-Mutant Lung Adenocarcinoma

scientific article published on 20 November 2019

Network meta-analysis of erlotinib, gefitinib, afatinib and icotinib in patients with advanced non-small-cell lung cancer harboring EGFR mutations

scientific article published in 2014

Neurokinin-1 Receptor Antagonist-Based Triple Regimens in Preventing Chemotherapy-Induced Nausea and Vomiting: A Network Meta-Analysis

scientific article published on 30 October 2016

Nintedanib Effect in Osimertinib-Induced Interstitial Pneumonia

scientific article published on 01 March 2020

Olanzapine-Based Triple Regimens Versus Neurokinin-1 Receptor Antagonist-Based Triple Regimens in Preventing Chemotherapy-Induced Nausea and Vomiting Associated with Highly Emetogenic Chemotherapy: A Network Meta-Analysis.

scientific article published on 12 January 2018

Ongoing Phase I Studies of Immune Checkpoint Inhibitors in China

article

Optimal prophylaxis of chemotherapy-induced nausea and vomiting for moderately emetogenic chemotherapy: a meta-analysis

scientific article published on 18 July 2018

Optimized selection of three major EGFR-TKIs in advanced EGFR-positive non-small cell lung cancer: a network meta-analysis

scientific article

Overexpression of wildtype EGFR is tumorigenic and denotes a therapeutic target in non-small cell lung cancer.

scientific article published on 4 December 2015

PD-L1 is remarkably over-expressed in EBV-associated pulmonary lymphoepithelioma-like carcinoma and related to poor disease-free survival

scientific article published on 24 August 2015

PI3K-AKT-mTOR pathway alterations in advanced NSCLC patients after progression on EGFR-TKI and clinical response to EGFR-TKI plus everolimus combination therapy

scientific article published on 01 August 2020

Patients with exon 19 deletion were associated with longer progression-free survival compared to those with L858R mutation after first-line EGFR-TKIs for advanced non-small cell lung cancer: a meta-analysis ⬇️

scientific article

Pemetrexed/carboplatin plus gefitinib as a first-line treatment for EGFR-mutant advanced nonsmall cell lung cancer: a Bayesian network meta-analysis

scientific article published on 30 December 2019

Pharmacokinetic and Pharmacodynamic Analyses of 5-Fluorouracil in East-Asian Patients with Nasopharyngeal Carcinoma.

scientific article published in October 2016

Preclinical characterization and phase 1 results of ADG106 in patients with advanced solid tumors and non-Hodgkin’s lymphoma

scholarly article

Preferable background filtering for next-generation sequencing analysis in non-small cell lung cancer: pericarcinomatous tissues or peripheral blood lymphocytes?

scientific article published on 13 June 2019

Pretreatment Albumin/Globulin Ratio Predicts the Prognosis for Small-Cell Lung Cancer

scientific article published on March 2016

Ratio of C-Reactive Protein/Albumin is An Inflammatory Prognostic Score for Predicting Overall Survival of Patients with Small-cell Lung Cancer

scientific article published on 18 June 2015

Retraction Note: p300 promotes proliferation, migration, and invasion via inducing epithelial-mesenchymal transition in non-small cell lung cancer cells

scientific article published in 2023

Risk of second primary malignancy after non-small cell lung cancer: a competing risk nomogram based on the SEER database

scientific article published on 01 September 2019

Risk of treatment-related deaths with vascular endothelial growth factor receptor tyrosine kinase inhibitors: a meta-analysis of 41 randomized controlled trials

scientific article

Serum low-density lipoprotein and low-density lipoprotein expression level at diagnosis are favorable prognostic factors in patients with small-cell lung cancer (SCLC).

scientific article

Serum proteomic study on EGFR-TKIs target treatment for patients with NSCLC.

scientific article

Severe delayed pulmonary toxicity following PD-L1-specific CAR-T cell therapy for non-small cell lung cancer

scientific article published on 09 October 2020

Suicide among cancer patients: adolescents and young adult (AYA) versus all-age patients

scientific article published on 01 November 2019

The ACTIVE study protocol: apatinib or placebo plus gefitinib as first-line treatment for patients with EGFR-mutant advanced non-small cell lung cancer (CTONG1706)

scientific article published on 07 November 2019

The Difference of Clinical Characteristics Between Patients With Exon 19 Deletion and Those With L858R Mutation in Nonsmall Cell Lung Cancer

scientific article

The analysis of pharmacokinetic and pharmacogenomic impact on gefitinib efficacy in advanced non-small cell lung cancer patients: results from a prospective cohort study

scientific article published on 01 December 2019

The association between PD-L1 and EGFR status and the prognostic value of PD-L1 in advanced non-small cell lung cancer patients treated with EGFR-TKIs

scientific article

The comparison of EGFR-TKI failure modes and subsequent management between exon 19 deletion and exon 21 L858R mutation in advanced non-small-cell lung cancer

scientific article published on 2 July 2017

The correlations of tumor mutational burden among single-region tissue, multi-region tissues and blood in non-small cell lung cancer

scientific article published on 03 April 2019

The effectiveness of RECIST on survival in patients with NSCLC receiving chemotherapy with or without target agents as first-line treatment

scientific article

The efficacy and safety of nivolumab in previously treated advanced non-small-cell lung cancer: a meta-analysis of prospective clinical trials

scientific article

The efficacy and toxicity of afatinib in advanced EGFR-positive non-small-cell lung cancer patients after failure of first-generation tyrosine kinase inhibitors: a systematic review and meta-analysis

scientific article

The efficacy of combining antiangiogenic agents with chemotherapy for patients with advanced non-small cell lung cancer who failed first-line chemotherapy: a systematic review and meta-analysis

scientific article published on 2 June 2015

The efficacy of first-line chemotherapy is associated with KRAS mutation status in patients with advanced non-small cell lung cancer: a meta-analysis.

scientific article

The expression of plakoglobin is a potential prognostic biomarker for patients with surgically resected lung adenocarcinoma

scientific article published on 25 February 2016

The perception gap of chemotherapy-induced adverse events between doctors and cancer patients: an observational study in China

scientific article published on 29 July 2020

The prognostic nutritional index (PNI) predicts overall survival of small-cell lung cancer patients

scientific article published on 20 December 2014

Upregulation of PD-L1 by EGFR Activation Mediates the Immune Escape in EGFR-Driven NSCLC: Implication for Optional Immune Targeted Therapy for NSCLC Patients with EGFR Mutation

scientific article

Upregulation of PD-L1 by EML4-ALK fusion protein mediates the immune escape in ALK positive NSCLC: Implication for optional anti-PD-1/PD-L1 immune therapy for ALK-TKIs sensitive and resistant NSCLC patients

scientific article published on 21 December 2015

p300 promotes proliferation, migration, and invasion via inducing epithelial-mesenchymal transition in non-small cell lung cancer cells.

scientific article published on 7 June 2018

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