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List of works by Wayne J Hawthorne

A fluorescent timer reporter enables sorting of insulin secretory granules by age

scientific article published on 27 April 2020

A novel, customized 3D-printed perfusion chamber for normothermic machine perfusion of the kidney

scientific article published on 28 October 2018

A preexistent hypoxic gene signature predicts impaired islet graft function and glucose homeostasis

scientific article

A systematic review and meta-analysis of cold in situ perfusion and preservation for pancreas transplantation.

scientific article

A systematic review and meta-analysis of cold in situ perfusion and preservation of the hepatic allograft: working towards a unified approach.

scientific article

Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice ⬇️

scientific article published on March 8, 2012

Advances in organ preservation for transplantation

scientific article published on 4 August 2016

Anti-CD2 producing pig xenografts effect localized depletion of human T cells in a huSCID model

scientific article

Antiproliferative effects of low molecular weight heparin

scientific article published in September 2004

Aortic Versus Dual Perfusion for Retrieval of the Liver After Brain Death: A National Registry Analysis

scientific article published on 01 November 2018

Association between islet xenograft rejection mediated by activated macrophages and upregulated chemokines

scientific article published on 01 February 2007

Australia and New Zealand Islet and Pancreas Transplant Registry Annual Report 2018-Islet Donations, Islet Isolations, and Islet Transplants

article

Australia and New Zealand Islet and Pancreas Transplant Registry Annual Report 2019: Islet Donations, Islet Isolations, and Islet Transplants

scientific article published on 08 June 2020

Brief Normothermic Machine Perfusion Rejuvenates Discarded Human Kidneys

scientific article published on 08 October 2019

CD4+ T cells initiate pancreatic islet xenograft rejection via an interferon-gamma-dependent recruitment of macrophages and natural killer cells

scientific article published on 01 February 2002

Characterization of PERV in a new conserved pig herd as potential donor animals for xenotransplantation in China

scientific article

Characterization of the Human Pancreas Side Population as a Potential Reservoir of Adult Stem Cells

scientific article published on 10 November 2017

Characterization of the swine major histocompatibility complex alleles at eight loci in Westran pigs.

scientific article published in July 2005

Characterizing the Mechanistic Pathways of the Instant Blood-Mediated Inflammatory Reaction in Xenogeneic Neonatal Islet Cell Transplantation

scientific article published on 19 May 2016

Chemokine and toll-like receptor signaling in macrophage mediated islet xenograft rejection.

scientific article published in January 2007

Clinical Islet Isolation

scientific article published on 01 January 2016

Clinical islet transplantation in type 1 diabetes mellitus: results of Australia's first trial

scientific article published in March 2006

Clonidine inhibits anti-non-Gal IgM xenoantibody elicited in multiple pig-to-primate models.

scientific article published on 21 October 2015

Culture of Transplant Perfusate Using BACTEC Technology and Antibiotic Prophylaxis Influences Wound Complications Within a Kidney Transplant and SPK Transplant Cohort

scientific article published on 21 June 2020

Current status of islet xenotransplantation.

scientific article published on 04 August 2015

Dual kidney transplant techniques: A systematic review

scientific article

Effectiveness of Helminth Therapy in the Prevention of Allograft Rejection: A Systematic Review of Allogeneic Transplantation

scientific article published on 07 August 2020

En bloc paediatric kidney transplant: is this the best use of a scarce resource?

scientific article published on 01 January 2009

Endovascular Management of Mycotic Pseudoaneurysm After Pancreas Transplantation: Case Report and Literature Review

scientific article published on 17 February 2020

Enhanced suppression of the xenogeneic T-cell response in vitro by xenoantigen stimulated and expanded regulatory T cells

scientific article published on 01 January 2014

Epigenetic and Transcriptome Profiling Identifies a Population of Visceral Adipose-Derived Progenitor Cells with the Potential to Differentiate into an Endocrine Pancreatic Lineage

scientific article published on 30 October 2018

Erratum. Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice. Diabetes 2012;61:1180-1191

scientific article published on 01 February 2016

Evaluation of promoters for driving efficient transgene expression in neonatal porcine islets.

scientific article published on March 2007

Evolution of pancreas transplant surgery.

scientific article published on June 2010

Ex vivo-expanded baboon CD39 +  regulatory T cells prevent rejection of porcine islet xenografts in NOD-SCID IL-2rγ-/- mice reconstituted with baboon peripheral blood mononuclear cells

scientific article published on 30 September 2017

Excellent outcomes of simultaneous pancreas kidney transplantation in patients from rural and urban Australia: a national service experience.

scientific article

Expression of Pro- and Antiapoptotic Molecules of the Bcl-2 Family in Human Islets Postisolation

scholarly article by Peter D. Campbell et al published January 2012 in Cell Transplantation

Expression of pro- and antiapoptotic molecules of the Bcl-2 family in human islets postisolation

scientific article

Extra-corporeal normothermic machine perfusion of the porcine kidney: working towards future utilization in Australasia

scientific article published on 14 December 2017

Fate of Abstracts Presented at the Transplantation Society of Australia and New Zealand Annual Scientific Meetings

scientific article published on 13 December 2020

First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--Chapter 3: Porcine islet product manufacturing and release testing crit

scientific article published on 29 February 2016

First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--Chapter 4: pre-clinical efficacy and complication data required to just

scientific article

FokI-dCas9 mediates high-fidelity genome editing in pigs

scientific article published on 12 August 2019

Gene therapy in diabetes ⬇️

scientific article published on June 9, 2010

Genetic and functional evaluation of the level of inbreeding of the Westran pig: a herd with potential for use in xenotransplantation

scientific article published on 01 July 2005

Genetic strategies to bring islet xenotransplantation to the clinic.

scientific article published on 11 August 2016

Growth-promoting effect of Rh(D) antibody on human pancreatic islet cells

scientific article

Hepatic artery vs. portal vein infusion of microbeads: a large animal pre-clinical model evaluating the intrahepatic capacity for cell infusion and imaging

scientific article published on May 2010

Human islet cells are killed by BID-independent mechanisms in response to FAS ligand

scientific article

Human islets express a marked proinflammatory molecular signature prior to transplantation.

scientific article published on 8 March 2012

Human regulatory macrophages are potent in suppression of the xenoimmune response via indoleamine-2,3-dioxygenase-involved mechanism(s).

scientific article published on 2 August 2017

Human thrombomodulin regulates complement activation as well as the coagulation cascade in xeno-immune response

scientific article published on 14 July 2015

Hypoxia-Inducible Factor-1α (HIF-1α) Potentiates β-Cell Survival after Islet Transplantation of Human and Mouse Islets ⬇️

scientific article published on June 15, 2012

Hypoxia-inducible factor-1alpha regulates beta cell function in mouse and human islets

scientific journal article

In Vivo Costimulation Blockade-Induced Regulatory T Cells Demonstrate Dominant and Specific Tolerance to Porcine Islet Xenografts

scientific article published on 21 September 2016

In vitro expanded human CD4+CD25+ regulatory T cells are potent suppressors of T-cell-mediated xenogeneic responses

scientific article published in June 2008

In vitro suppression of xenoimmune-mediated macrophage activation by human CD4+CD25+ regulatory T cells

scientific article published on 01 September 2008

Involvement of CCR5 signaling in macrophage recruitment to porcine islet xenografts

scientific article published on 01 November 2005

Islet Transplantation Provides Superior Glycemic Control With Less Hypoglycemia Compared With Continuous Subcutaneous Insulin Infusion or Multiple Daily Insulin Injections

scientific article

Islet xenotransplantation: progress towards a clinical therapy

Localization of dipeptidyl peptidase-4 (CD26) to human pancreatic ducts and islet alpha cells

scientific article published on 26 October 2015

Long-term cultured neonatal islet cell clusters demonstrate better outcomes for reversal of diabetes: in vivo and molecular profiles

scientific article

Loss of ARNT/HIF1beta mediates altered gene expression and pancreatic-islet dysfunction in human type 2 diabetes

scientific article

Low Dose IL-2 Combined with Rapamycin Led to an Expansion of CD4+CD25+FOXP3+ Tregs and Prolonged Human Islet-allograft Survival in Humanized Mice

scientific article published on 07 May 2020

Management of primary symptomatic lymphocele after kidney transplantation: a systematic review

scientific article published on September 2011

Maximizing kidneys for transplantation using machine perfusion: from the past to the future: A comprehensive systematic review and meta-analysis.

scientific article published on October 2016

Memory T cells are significantly increased in rejected liver allografts of rhesus monkeys.

scientific article published on 18 November 2017

Monitoring Glycolysis and Respiration Highlights Metabolic Inflexibility of Cryptococcus neoformans

scientific article published on 21 August 2020

Moving Toward Transplant Tolerance: Is Targeting Donor Antigen-presenting Cells the Key?

scientific article published on 01 April 2020

Necessities for a Clinical Islet Program

scientific article published on 01 January 2016

New methodology for assessment of intimal hyperplasia of vascular prostheses

scientific article published on 01 September 2002

Optimal Culture Methods and Microbial Contamination During Kidney Ex Vivo Normothermic Perfusion

scientific article published on 01 September 2018

Optimal surgical management in kidney and pancreas transplantation to minimise wound complications: A systematic review and meta-analysis

scholarly article by Sara Shahrestani et al published September 2018 in Annals of medicine and surgery (2012)

Optimizing transduction of pig islet cell clusters for xenotransplantation.

scientific article published in January 2009

Partnership of the International Xenotransplantation Association, The Transplantation Society, and World Health Organization in the development of guidance documents and policies for xenotransplantation including the Changsha communiqué

scientific article published on 25 May 2020

Perigraft adventitia and intima remodeling after synthetic patch implantation in sheep carotid artery: role of apoptosis and proliferation.

scientific article published in August 2002

Pharmacologic targeting of renal ischemia-reperfusion injury using a normothermic machine perfusion platform

scientific article published on 24 April 2020

Preclinical screening for acute toxicity of therapeutic monoclonal antibodies in a hu-SCID model.

scientific article

Pre‐clinical model of composite foetal pig pancreas fragment/renal xenotransplantation to treat renal failure and diabetes ⬇️

scientific article published on 01 November 2011

Regulation of Clinical Xenotransplantation-Time for a Reappraisal

scientific article

Renal transplantation: better fat than thin

scientific article published on 3 January 2014

Reply

scientific article published in August 2018

Requirement of MyD88 for macrophage-mediated islet xenograft rejection after adoptive transfer

scientific article published on 01 March 2007

Rhesus monkeys and baboons develop clotting factor VIII inhibitors in response to porcine endothelial cells or islets

scientific article

Risk Factors for Early Pancreatic Allograft Thrombosis Following Simultaneous Pancreas-Kidney Transplantation: A Systematic Review

scientific article published on 01 January 2020

Selective rejection of porcine islet xenografts by macrophages

scientific article published in September 2008

Single-incision laparoscopic intraperitoneal onlay mesh repair for the treatment of multiple recurrent inguinal hernias

scientific article

Single-incision laparoscopic repair of Spigelian hernia

scientific article

Single-port onlay mesh repair of recurrent inguinal hernias after failed anterior and laparoscopic repairs

scientific article published in January 2015

Sir Bob Elliot-"In Memoriam"

scientific article published on 01 September 2020

Standardisation of flow cytometry for whole blood immunophenotyping of islet transplant and transplant clinical trial recipients.

scientific article published on 22 May 2019

Strategies to minimize adhesions to intraperitoneally placed mesh in laparoscopic ventral hernia repair

scientific article published on January 2012

Subcapsular Fetal Pig Pancreas Fragment Transplantation Provides Normal Blood Glucose Control in a Preclinical Model of Diabetes ⬇️

scientific article published on March 15, 2011

Successful Expectant Management of Nonocclusive Thrombosis in Simultaneous Pancreas-Kidney Transplantation

scientific article published on 05 January 2021

Surgical Morbidity of Simultaneous Kidney and Pancreas Transplantation: A Single-Centre Experience in the Tacrolimus Era

T cell-activated macrophages are capable of both recognition and rejection of pancreatic islet xenografts

scientific article published in March 2003

Targeted insertion of an anti-CD2 monoclonal antibody transgene into the GGTA1 locus in pigs using FokI-dCas9.

scientific article published on 16 August 2017

The Evolution of Kidney Transplantation Surgery Into the Robotic Era and Its Prospects for Obese Recipients

scientific article published on 01 October 2018

The importance of tissue factor expression by porcine NICC in triggering IBMIR in the xenograft setting

scientific article published on 01 April 2011

The linear cutting stapler for enteric anastomosis: a new technique in pancreas transplantation.

scientific article published on November 2006

The long noncoding RNA MALAT1 predicts human pancreatic islet isolation quality

scientific article published on 30 July 2019

Third WHO Global Consultation on Regulatory Requirements for Xenotransplantation Clinical Trials, Changsha, Hunan, China December 12-14, 2018: "The 2018 Changsha Communiqué" The 10-Year Anniversary of The International Consultation on Xenotransplant

scientific article published on 01 March 2019

Thomas Starzl-Visionary and xenotransplantation pioneer: Commentary from the International Xenotransplant Association Vanguard Committee.

scientific article published in March 2017

Tolerance induction in a large-animal model using total lymphoid irradiation and intrathymic bone marrow

scientific article

Transplantation of xenogeneic islets: are we there yet?

scientific article published on October 2013

Transplantation sites for human and murine islets.

scientific article published on 22 July 2017

Transplantation sites for porcine islets.

scientific article

Use of the harmonic scalpel in cold phase recovery of the pancreas for transplantation: the westmead technique.

scientific article published on 24 March 2016

Vascular closure staples reduce intimal hyperplasia in prosthesis implantation

scientific article published on 01 December 2002

Xenoantibody response to porcine islet cell transplantation using GTKO, CD55, CD59, and fucosyltransferase multiple transgenic donors

scientific article

Xenogeneic transplantation and tolerance in the era of CRISPR-Cas9

scientific article published on 01 February 2019

Xenotransplantation in Australia: Development of the regulatory process

scientific article published on 07 June 2020

Xenotransplantation literature update, January/February 2018

scientific article published on 01 March 2018

Xenotransplantation literature update, November/December 2019

scientific article published on 26 January 2020

Xenotransplantation literature update, September/October 2019

scientific article published on 25 November 2019

β Cell Hypoxia-Inducible Factor-1α Is Required for the Prevention of Type 1 Diabetes

scientific article published on 01 May 2019

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