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List of works by Naoki Hiramatsu

A case of gastric mixed adenoneuroendocrine carcinoma with difficulty in diagnosis before endoscopic submucosal dissection

scientific article published on January 2016

A randomized, double-blind study to evaluate the acid-inhibitory effect of vonoprazan (20 mg and 40 mg) in patients with proton-pump inhibitor-resistant erosive esophagitis

scientific article

Activation of metabotropic glutamate 2/3 receptors attenuates methamphetamine-induced hyperlocomotion and increase in prefrontal serotonergic neurotransmission

scientific article published on 13 April 2011

Advanced gastric cancer deriving from submucosal heterotopic gastric glands based on pathological diagnosis

scientific article

Age and Total Ribavirin Dose are Independent Predictors of Relapse after Interferon Therapy in Chronic Hepatitis C Revealed by Data Mining Analysis ⬇️

scientific article published on January 1, 2012

Alterations in microRNA expression profile in HCV-infected hepatoma cells: involvement of miR-491 in regulation of HCV replication via the PI3 kinase/Akt pathway.

scientific article

BH3-only activator proteins Bid and Bim are dispensable for Bak/Bax-dependent thrombocyte apoptosis induced by Bcl-xL deficiency: molecular requisites for the mitochondrial pathway to apoptosis in platelets

scientific article

BH3-only protein bid participates in the Bcl-2 network in healthy liver cells

scientific article published on December 2009

Baseline quasispecies selection and novel mutations contribute to emerging resistance-associated substitutions in hepatitis C virus after direct-acting antiviral treatment.

scientific article published on 30 January 2017

Concanavalin a injection activates intrahepatic innate immune cells to provoke an antitumor effect in murine liver

scientific article

Concomitant use of romiplostim and chemotherapy for advanced rectal cancer associated with idiopathic thrombocytopenic purpura

scientific article

Data mining model using simple and readily available factors could identify patients at high risk for hepatocellular carcinoma in chronic hepatitis C ⬇️

scientific article published on October 23, 2011

Declining incidence of hepatocellular carcinoma in Osaka, Japan, from 1990 to 2003.

scientific article published on June 2008

Effects of preceding interferon therapy on outcome after surgery for hepatitis C virus-related hepatocellular carcinoma

scientific article published in September 2010

Efficacy of re-treatment with pegylated interferon plus ribavirin combination therapy for patients with chronic hepatitis C in Japan ⬇️

scientific article published on May 3, 2011

Evaluation of Fucosylated Haptoglobin and Mac-2 Binding Protein as Serum Biomarkers to Estimate Liver Fibrosis in Patients with Chronic Hepatitis C.

scientific article

Fibroblast growth factor‐2 enhances NK sensitivity of hepatocellular carcinoma cells ⬇️

scientific article published on April 25, 2011

Glycomic analysis of alpha-fetoprotein L3 in hepatoma cell lines and hepatocellular carcinoma patients

scientific article

Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice

scientific article published on 11 July 2011

Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma

scientific article

Initial viral response is the most powerful predictor of the emergence of YMDD mutant virus in chronic hepatitis B patients treated with lamivudine

scientific article published on 21 November 2007

Interferon-α suppresses hepatitis B virus enhancer II activity via the protein kinase C pathway.

scientific article

Interleukin-1β enhances the production of soluble MICA in human hepatocellular carcinoma

scientific article published on September 2012

Involvement of GABAA receptors in 5-HT1A and σ1 receptor synergism on prefrontal dopaminergic transmission under circulating neurosteroid deficiency

scientific article published on 23 June 2016

Involvement of dendritic cell frequency and function in virological relapse in pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C patients

scientific article published in May 2007

Juvenile hepatocellular carcinoma with congestive liver cirrhosis.

scientific article

Lansoprazole for secondary prevention of gastric or duodenal ulcers associated with long-term low-dose aspirin therapy: results of a prospective, multicenter, double-blind, randomized, double-dummy, active-controlled trial ⬇️

scientific article published on April 16, 2011

Lansoprazole for secondary prevention of gastric or duodenal ulcers associated with long-term non-steroidal anti-inflammatory drug (NSAID) therapy: results of a prospective, multicenter, double-blind, randomized, double-dummy, active-controlled trial ⬇️

scientific article published on March 3, 2012

Mcl-1 and Bcl-xL cooperatively maintain integrity of hepatocytes in developing and adult murine liver

scientific article published on October 2009

Metabotropic glutamate 2/3 receptor antagonists improve behavioral and prefrontal dopaminergic alterations in the chronic corticosterone-induced depression model in mice.

scientific article published on 25 September 2012

Natural killer cell is a major producer of interferon gamma that is critical for the IL-12-induced anti-tumor effect in mice

scientific article published on 16 September 2009

Negative regulation of NK cell activities by inhibitory receptor CD94/NKG2A leads to altered NK cell-induced modulation of dendritic cell functions in chronic hepatitis C virus infection

scientific article

Post-treatment levels of α-fetoprotein predict incidence of hepatocellular carcinoma after interferon therapy

scientific article published on 7 December 2013

Pretreatment prediction of response to peginterferon plus ribavirin therapy in genotype 1 chronic hepatitis C using data mining analysis ⬇️

scientific article published on September 10, 2010

Psychopharmacology of combined activation of the serotonin1A and σ1 receptors

scientific article

Role of the 5-HT1A autoreceptor in the enhancement of fluvoxamine-induced increases in prefrontal dopamine release by adrenalectomy/castration in mice.

scientific article

S100A8 Production in CXCR2-Expressing CD11b+Gr-1high Cells Aggravates Hepatitis in Mice Fed a High-Fat and High-Cholesterol Diet

scientific article published on 25 November 2015

Sequences in the interferon sensitivity‐determining region and core region of hepatitis C virus impact pretreatment prediction of response to PEG‐interferon plus ribavirin: Data mining analysis ⬇️

scientific article published on March 1, 2011

Serum Fucosylated Haptoglobin as a Novel Diagnostic Biomarker for Predicting Hepatocyte Ballooning and Nonalcoholic Steatohepatitis

scientific article

Solitary fibrous tumor of the liver from development to resection

scientific article

Suppression of signal transducers and activators of transcription 1 in hepatocellular carcinoma is associated with tumor progression.

scientific article published on 28 June 2012

The Bcl-2 homology domain 3 (BH3)-only proteins Bim and bid are functionally active and restrained by anti-apoptotic Bcl-2 family proteins in healthy liver.

scientific article published on 28 August 2013

The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib

scientific article published on October 2010

The Hepatitis B Virus Genotype Affects the Persistence of Viral Replication in Immunodeficient NOG Mice. ⬇️

scientific article published on 14 December 2015

The combination therapy of α-galactosylceramide and 5-fluorouracil showed antitumor effect synergistically against liver tumor in mice.

scientific article published on 13 March 2013

The impact of an inosine triphosphate pyrophosphatase genotype on bilirubin increase in chronic hepatitis C patients treated with simeprevir, pegylated interferon plus ribavirin

scientific article published on 30 July 2015

The selective metabotropic glutamate 2/3 receptor agonist MGS0028 reverses psychomotor abnormalities and recognition memory deficits in mice lacking the pituitary adenylate cyclase-activating polypeptide.

scientific article published in February 2013

Valine, the branched-chain amino acid, suppresses hepatitis C virus RNA replication but promotes infectious particle formation.

scientific article published on 24 June 2013

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