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List of works by Clifford Lingwood

A major fraction of glycosphingolipids in model and cellular cholesterol-containing membranes is undetectable by their binding proteins

scientific article

A novel soluble analog of the HIV-1 fusion cofactor, globotriaosylceramide (Gb(3)), eliminates the cholesterol requirement for high affinity gp120/Gb(3) interaction

scientific article published in October 2002

A novel soluble mimic of the glycolipid, globotriaosyl ceramide inhibits HIV infection

scientific article published on February 2006

A soluble sulfogalactosyl ceramide mimic promotes Delta F508 CFTR escape from endoplasmic reticulum associated degradation

scientific article published on April 2009

A synthetic globotriaosylceramide analogue inhibits HIV-1 infection in vitro by two mechanisms.

scientific article

Adamantyl Glycosphingolipids Provide a New Approach to the Selective Regulation of Cellular Glycosphingolipid Metabolism ⬇️

scientific article published on April 25, 2011

Brefeldin A and filipin distinguish two globotriaosyl ceramide/verotoxin-1 intracellular trafficking pathways involved in Vero cell cytotoxicity

scientific article published on 21 April 2004

CD4+ T-cells are unable to express the HIV natural resistance factor globotriosylceramide ⬇️

scientific article published on March 27, 2013

Cholesterol masks membrane glycosphingolipid tumor-associated antigens to reduce their immunodetection in human cancer biopsies ⬇️

scientific article published on July 31, 2013

Cholesterol modulates glycolipid conformation and receptor activity

Comparison of detection methods for cell surface globotriaosylceramide ⬇️

scientific article published on June 24, 2011

Detergent-resistant globotriaosyl ceramide may define verotoxin/glomeruli-restricted hemolytic uremic syndrome pathology

scientific article

Differential carbohydrate epitope recognition of globotriaosyl ceramide by verotoxins and a monoclonal antibody

scientific article

Differential intracellular transport and binding of verotoxin 1 and verotoxin 2 to globotriaosylceramide-containing lipid assemblies

scientific article

Differential tissue targeting and pathogenesis of verotoxins 1 and 2 in the mouse animal model

scientific article

Effect of globotriaosyl ceramide fatty acid alpha-hydroxylation on the binding by verotoxin 1 and verotoxin 2.

scientific article published in August 2002

Endoplasmic Reticulum-Targeted Subunit Toxins Provide a New Approach to Rescue Misfolded Mutant Proteins and Revert Cell Models of Genetic Diseases

scientific article

Expression of receptors for verotoxin 1 from Escherichia coli O157 on bovine intestinal epithelium

scientific article published in February 2002

Fatty acid-dependent globotriaosyl ceramide receptor function in detergent resistant model membranes

scientific article published on 20 August 2008

Generation of receptor-active, globotriaosyl ceramide/cholesterol lipid 'rafts' in vitro : A new assay to define factors affecting glycosphingolipid receptor activity

scientific article published in January 2004

Glycolipid-Dependent, Protease Sensitive Internalization of Pseudomonas aeruginosa Into Cultured Human Respiratory Epithelial Cells ⬇️

scientific article published on December 13, 2010

Glycosphingolipid functions

scientific article published on July 2011

Glycosphingolipid storage in Fabry mice extends beyond globotriaosylceramide and is affected by ABCB1 depletion.

scientific article published on 13 October 2016

Induction of HIV-1 resistance: cell susceptibility to infection is an inverse function of globotriaosyl ceramide levels

scientific article published on 8 October 2008

Inhibition of Rab prenylation by statins induces cellular glycosphingolipid remodeling

scientific article published on 24 September 2015

Inhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen

scientific article published on 04 February 2009

Inhibition of multidrug resistance by adamantylgb3, a globotriaosylceramide analog

scientific article

Interaction of the verotoxin 1B subunit with soluble aminodeoxy analogues of globotriaosyl ceramides

scientific article

Methods for the identification of host receptors for Shiga toxin

scientific article

Methods for the purification of Shiga toxin 1.

scientific article

New aspects of the regulation of glycosphingolipid receptor function

scientific article published on January 2010

Quantitative analysis of the lipidomes of the influenza virus envelope and MDCK cell apical membrane

scientific article published on 16 January 2012

Role of multiple drug resistance protein 1 in neutral but not acidic glycosphingolipid biosynthesis

scientific article published on 8 December 2003

Shiga toxin 2 causes apoptosis in human brain microvascular endothelial cells via C/EBP homologous protein

scientific article

Shiga toxin receptor glycolipid binding. Pathology and utility

scientific article

Soluble adamantyl glycosphingolipid analogs as probes of glycosphingolipid function

scientific article published on January 2006

Structure-dependent Pseudoreceptor Intracellular Traffic of Adamantyl Globotriaosyl Ceramide Mimics ⬇️

scientific article published on March 14, 2012

Suppression of Adenovirus Replication by Cardiotonic Steroids

scientific article published on 23 November 2016

Synthesis of a novel photoactivatable glucosylceramide cross-linker

scientific article published on 13 July 2016

The human P(k) histo-blood group antigen provides protection against HIV-1 infection.

scientific article

The role of glycosphingolipids in HIV/AIDS

scientific article published on April 1, 2011

The sulfogalactose moiety of sulfoglycosphingolipids serves as a mimic of tyrosine phosphate in many recognition processes. Prediction and demonstration of Src homology 2 domain/sulfogalactose binding

scientific article published on 5 January 2005

The treatment of malignant meningioma with verotoxin

scientific article

Treatment of neutral glycosphingolipid lysosomal storage diseases via inhibition of the ABC drug transporter, MDR1. Cyclosporin A can lower serum and liver globotriaosyl ceramide levels in the Fabry mouse model

scientific article published on May 2006

Verotoxin 1 binding to intestinal crypt epithelial cells results in localization to lysosomes and abrogation of toxicity.

scientific article

Verotoxin A Subunit Protects Lymphocytes and T Cell Lines against X4 HIV Infection in Vitro ⬇️

scientific article published on December 14, 2012

Verotoxin sensitivity of ECV304 cells in vitro and in vivo in a xenograft tumour model: VT1 as a tumour neovascular marker

scientific article published on January 2003

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