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List of works by Leslie B Gordon

A novel somatic mutation achieves partial rescue in a child with Hutchinson-Gilford progeria syndrome

scientific article published on 05 December 2016

A prospective study of radiographic manifestations in Hutchinson-Gilford progeria syndrome

scientific article

Accumulation of mutant lamin A causes progressive changes in nuclear architecture in Hutchinson-Gilford progeria syndrome

scientific article

Age-dependent loss of MMP-3 in Hutchinson-Gilford progeria syndrome

scientific article

Aggrecan expression is substantially and abnormally upregulated in Hutchinson-Gilford Progeria Syndrome dermal fibroblasts.

scientific article published on 2 May 2006

Analyses of LMNA-negative juvenile progeroid cases confirms biallelic POLR3A mutations in Wiedemann-Rautenstrauch-like syndrome and expands the phenotypic spectrum of PYCR1 mutations

scientific article published on 19 November 2018

Association of Lonafarnib Treatment vs No Treatment With Mortality Rate in Patients With Hutchinson-Gilford Progeria Syndrome.

scientific article

Atherosclerosis in ancient humans, accelerated aging syndromes and normal aging: is lamin a protein a common link?

scientific article

Cardiac Abnormalities in Patients With Hutchinson-Gilford Progeria Syndrome

scientific article published on 21 February 2018

Cardiovascular pathology in Hutchinson-Gilford progeria: correlation with the vascular pathology of aging.

scientific article

Clinical Trial of the Protein Farnesylation Inhibitors Lonafarnib, Pravastatin, and Zoledronic Acid in Children With Hutchinson-Gilford Progeria Syndrome

scientific article published on July 2016

Clinical trial of a farnesyltransferase inhibitor in children with Hutchinson-Gilford progeria syndrome

scientific article

Defective lamin A-Rb signaling in Hutchinson-Gilford Progeria Syndrome and reversal by farnesyltransferase inhibition

scientific article

Disease progression in Hutchinson-Gilford progeria syndrome: impact on growth and development

scientific article published in October 2007

Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts.

scientific article

Extraskeletal Calcifications in Hutchinson-Gilford Progeria Syndrome

scientific article published on 08 May 2019

Highlights of the 2007 Progeria Research Foundation scientific workshop: progress in translational science

scientific article published on 01 August 2008

Hutchinson-Gilford progeria is a skeletal dysplasia

scientific article published on July 2011

Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody

scientific article

Hutchinson-Gilford progeria syndrome

scientific article published on 01 January 2015

Hyaluronan is not elevated in urine or serum in Hutchinson-Gilford Progeria Syndrome ⬇️

scientific article published on May 1, 2003

Impact of farnesylation inhibitors on survival in Hutchinson-Gilford progeria syndrome.

scientific article

In vivo base editing rescues Hutchinson-Gilford progeria syndrome in mice

scientific article published on 06 January 2021

Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome

scientific article

Initial cutaneous manifestations of Hutchinson-Gilford progeria syndrome

scientific article

Intermittent treatment with farnesyltransferase inhibitor and sulforaphane improves cellular homeostasis in Hutchinson-Gilford progeria fibroblasts

scientific article published on 18 July 2017

Mechanisms of premature vascular aging in children with Hutchinson-Gilford progeria syndrome

scientific article published on 14 November 2011

Microbiome at sites of gingival recession in children with Hutchinson-Gilford progeria syndrome

scientific article published on 19 February 2018

Naïve adult stem cells from patients with Hutchinson-Gilford progeria syndrome express low levels of progerin in vivo

scientific article published on 16 April 2012

Neurologic features of Hutchinson-Gilford progeria syndrome after lonafarnib treatment

scientific article

New approaches to progeria

scientific article published on October 2007

Ophthalmologic Features of Progeria

scientific article published on 26 July 2017

Otologic and audiologic manifestations of Hutchinson-Gilford progeria syndrome

scientific article

Phenotype and course of Hutchinson-Gilford progeria syndrome

scientific article

Progeria: Translational insights from cell biology ⬇️

scientific article published on October 1, 2012

Progeria: a paradigm for translational medicine.

scientific article published in January 2014

Progressive vascular smooth muscle cell defects in a mouse model of Hutchinson-Gilford progeria syndrome

scholarly article

Pubertal Progression in Adolescent Females with Progeria.

scientific article published on 16 December 2017

Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome ⬇️

scientific article (publication date: 15 May 2003)

Reduced adiponectin and HDL cholesterol without elevated C-reactive protein: clues to the biology of premature atherosclerosis in Hutchinson-Gilford Progeria Syndrome

scientific article

Skeletal maturation and long-bone growth patterns of patients with progeria: a retrospective study

scientific article published on 28 February 2020

Sulforaphane enhances progerin clearance in Hutchinson-Gilford progeria fibroblasts

scientific article

Survey of plasma proteins in children with progeria pre-therapy and on-therapy with lonafarnib

scientific article published on 17 January 2018

Temsirolimus Partially Rescues the Hutchinson-Gilford Progeria Cellular Phenotype

scientific article

The cell nucleus and aging: tantalizing clues and hopeful promises

scientific article published on 15 November 2005

The decision-making process and criteria in selecting candidate drugs for progeria clinical trials

scientific article published on 26 May 2016

The mutant form of lamin A that causes Hutchinson-Gilford progeria is a biomarker of cellular aging in human skin

scientific article

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