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List of works by Anthony J Coyle

A GM-CSF/IL-33 pathway facilitates allergic airway responses to sub-threshold house dust mite exposure

scientific article

A chitinase-like protein in the lung and circulation of patients with severe asthma

scientific article

A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system

scientific article

A glycoengineered anti‐CD19 antibody with potent antibody‐dependent cellular cytotoxicity activity in vitro and lymphoma growth inhibition in vivo ⬇️

scientific article published on September 9, 2011

Acute, but not resolved, influenza A infection enhances susceptibility to house dust mite-induced allergic disease

scientific article

Angiopoietin-2-driven vascular remodeling in airway inflammation

scientific article

B-cell depletion in vitro and in vivo with an afucosylated anti-CD19 antibody

scientific article published on 6 July 2010

B7-H3 promotes acute and chronic allograft rejection

scientific article

Capillary defects and exaggerated inflammatory response in the airways of EphA2-deficient mice

scientific article

Cell Type-Specific Recognition of Human Metapneumoviruses (HMPVs) by Retinoic Acid-Inducible Gene I (RIG-I) and TLR7 and Viral Interference of RIG-I Ligand Recognition by HMPV-B1 Phosphoprotein

scientific article

Characterization of Tiki, a New Family of Wnt-specific Metalloproteases

scientific article

Characterization of signaling pathways activated by the interleukin 1 (IL-1) receptor homologue T1/ST2. A role for Jun N-terminal kinase in IL-4 induction.

scientific article

Concurrent blockade of platelet-activating factor and histamine prevents life-threatening peanut-induced anaphylactic reactions

scientific article

Continuous exposure to house dust mite elicits chronic airway inflammation and structural remodeling

scientific article published on 3 November 2003

Contribution of the PD-1 ligands/PD-1 signaling pathway to dendritic cell-mediated CD4+ T cell activation

scientific article

Correction: Type I Interferon: Potential Therapeutic Target for Psoriasis?

scientific article

Cutaneous antigen priming via gene gun leads to skin-selective Th2 immune-inflammatory responses

scientific article published in February 2005

Cytosolic flagellin requires Ipaf for activation of caspase-1 and interleukin 1beta in salmonella-infected macrophages

scientific journal article

Development of Potential Pharmacodynamic and Diagnostic Markers for Anti-IFN-α Monoclonal Antibody Trials in Systemic Lupus Erythematosus

scientific article

Differential expression and function of breast regression protein 39 (BRP-39) in murine models of subacute cigarette smoke exposure and allergic airway inflammation ⬇️

scientific article published on April 7, 2011

Distinct immune effector pathways contribute to the full expression of peanut-induced anaphylactic reactions in mice

scientific article published in June 2011

Effect of GM-CSF on immune, inflammatory, and clinical responses to ragweed in a novel mouse model of mucosal sensitization

scientific article published in May 2003

Eosinophils Are Dispensable for Allergic Remodeling and Immunity in a Model of House Dust Mite–induced Airway Disease ⬇️

scientific article published on August 23, 2010

Essential role for the C5a receptor in regulating the effector phase of synovial infiltration and joint destruction in experimental arthritis

scientific article

Evaluation of inducible costimulator/B7-related protein-1 as a therapeutic target in a murine model of allergic airway inflammation

scientific article published in June 2003

Genomic-based high throughput screening identifies small molecules that differentially inhibit the antiviral and immunomodulatory effects of IFN-alpha

scientific article

Granulocyte macrophage colony-stimulating factor-driven respiratory mucosal sensitization induces Th2 differentiation and function independently of interleukin-4.

scientific article published in October 2002

HMGB1 and RAGE in inflammation and cancer

scientific article

ICOS controls the pool size of effector-memory and regulatory T cells.

scientific article

ICOS expression by activated human Th cells is enhanced by IL-12 and IL-23: increased ICOS expression enhances the effector function of both Th1 and Th2 cells

scientific article

IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway

scientific article (publication date: May 2003)

IL-1α/IL-1R1 expression in chronic obstructive pulmonary disease and mechanistic relevance to smoke-induced neutrophilia in mice

scientific article

IL-33, but not thymic stromal lymphopoietin or IL-25, is central to mite and peanut allergic sensitization.

scientific article published on 21 September 2012

IL-4 increases type 2, but not type 1, cytokine production in CD8+ T cells from mild atopic asthmatics

scientific article

IL-9 governs allergen-induced mast cell numbers in the lung and chronic remodeling of the airways

scientific article

IL‐9 is a Th17‐derived cytokine that limits pathogenic activity in organ‐specific autoimmune disease ⬇️

scientific article published on February 24, 2011

Identification and characterization of SF2000 and SF2001, two new members of the immune receptor SLAM/CD2 family

scientific article (publication date: February 2002)

Impact of CD40 ligand, B cells, and mast cells in peanut-induced anaphylactic responses

scientific article published in November 2007

In vivo-to-in silico iterations to investigate aeroallergen-host interactions

scientific article

Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance

scientific journal article

Intranasal exposure of mice to house dust mite elicits allergic airway inflammation via a GM-CSF-mediated mechanism

scientific article published in November 2004

Lung chitinolytic activity and chitotriosidase are elevated in chronic obstructive pulmonary disease and contribute to lung inflammation

scientific article

Macrophage impairment underlies airway occlusion in primary respiratory syncytial virus bronchiolitis

scientific article published in December 2008

Mast cells are essential intermediaries in regulatory T-cell tolerance

scientific article

Mycophenolic Acid Differentially Impacts B Cell Function Depending on the Stage of Differentiation ⬇️

scientific article published on August 26, 2011

Neutralization of interferon-alpha/beta-inducible genes and downstream effect in a phase I trial of an anti-interferon-alpha monoclonal antibody in systemic lupus erythematosus

scientific article (publication date: June 2009)

Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan

scientific article (publication date: 6 June 2003)

Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island

scientific article

Novel Anti-TM4SF1 Antibody-Drug Conjugates with Activity against Tumor Cells and Tumor Vasculature

scientific article

Opposing Roles of Membrane and Soluble Forms of the Receptor for Advanced Glycation End Products in Primary Respiratory Syncytial Virus Infection ⬇️

scientific article published on January 18, 2012

Psoriasiform dermatitis is driven by IL-36-mediated DC-keratinocyte crosstalk

scientific journal article

RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA

scientific article

RAGE is a nucleic acid receptor that promotes inflammatory responses to DNA.

scientific article published in May 2014

RSV-induced bronchial epithelial cell PD-L1 expression inhibits CD8+ T cell nonspecific antiviral activity

scientific article

Role of CCL11 in eosinophilic lung disease during respiratory syncytial virus infection

scientific article

Role of CCR5 in IFN-gamma-induced and cigarette smoke-induced emphysema

scientific article

Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis

scientific article published on 04 May 2009

Role of the caspase-1 inflammasome in Salmonella typhimurium pathogenesis

scientific article

Safety profile, pharmacokinetics, and biologic activity of MEDI-563, an anti-IL-5 receptor alpha antibody, in a phase I study of subjects with mild asthma

scientific article published in June 2010

Shifting of immune responsiveness to house dust mite by influenza A infection: genomic insights.

scientific article published on 14 December 2011

Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

scientific article

Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance.

scientific article

Type I IFNs Regulate Inflammation, Vasculopathy, and Fibrosis in Chronic Cutaneous Graft-versus-Host Disease

scientific article published on 25 May 2016

Type I interferon: potential therapeutic target for psoriasis?

scientific article

Type I interferons produced by resident renal cells may promote end-organ disease in autoantibody-mediated glomerulonephritis.

scientific article

YKL-40 is elevated in patients with chronic obstructive pulmonary disease and activates alveolar macrophages

scientific article published on October 2008

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