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List of works by David S. Miller

17-β-Estradiol: a powerful modulator of blood-brain barrier BCRP activity

scientific article

1α,25-Dihydroxyvitamin D3-liganded vitamin D receptor increases expression and transport activity of P-glycoprotein in isolated rat brain capillaries and human and rat brain microvessel endothelial cells

scientific article published on November 2012

ABC Transporter Function and Regulation at the Blood–Spinal Cord Barrier ⬇️

scientific article published on April 4, 2012

ABC transporter regulation by signaling at the blood-brain barrier: relevance to pharmacology

scientific article

ABC transporter-driven pharmacoresistance in Amyotrophic Lateral Sclerosis

scientific article

Activating PKC-β1 at the blood—brain barrier reverses induction of P-glycoprotein activity by dioxin and restores drug delivery to the CNS ⬇️

scientific article published on April 13, 2011

Activation of PKC isoform beta(I) at the blood-brain barrier rapidly decreases P-glycoprotein activity and enhances drug delivery to the brain

scientific article

Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease

scientific article published in April 2005

Alkylglycerol opening of the blood-brain barrier to small and large fluorescence markers in normal and C6 glioma-bearing rats and isolated rat brain capillaries

scientific article

Aryl hydrocarbon receptor ligands increase ABC transporter activity and protein expression in killifish (Fundulus heteroclitus) renal proximal tubules

scientific article published on 01 September 2019

Aryl hydrocarbon receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier

scientific article

Aβ40 Reduces P-Glycoprotein at the Blood-Brain Barrier through the Ubiquitin-Proteasome Pathway.

scientific article published on February 2016

Ceramide 1-Phosphate Increases P-Glycoprotein Transport Activity at the Blood-Brain Barrier via Prostaglandin E2 Signaling

scientific article published on 24 January 2017

Compound profiling for P-glycoprotein at the blood-brain barrier using a microplate screening system

scientific article published in August 2003

Confocal imaging of organic anion transport in intact rat choroid plexus

scientific article

Confocal imaging of xenobiotic transport across the blood‐brain barrier ⬇️

scientific article published on November 1, 2003

Confocal imaging of xenobiotic transport across the choroid plexus

scientific article published in October 2004

Constitutive androstane receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier

scientific article

Coordinated nuclear receptor regulation of the efflux transporter, Mrp2, and the phase-II metabolizing enzyme, GSTpi, at the blood-brain barrier

scientific journal article

Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein up-regulation at the blood-brain barrier

scientific article

Effects of deep hypothermic circulatory arrest on the blood brain barrier in a cardiopulmonary bypass model--a pilot study.

scientific article

Endothelin and calciotropic hormones share regulatory pathways in multidrug resistance protein 2-mediated transport

scientific article published on 15 August 2006

Expression systems for cloned xenobiotic transporters

scientific article

Fluorescein-methotrexate transport in dogfish shark (Squalus acanthias) choroid plexus

scientific article published on 23 February 2006

Fluorescein-methotrexate transport in rat choroid plexus analyzed using confocal microscopy

scientific article

Functional regulation of P-glycoprotein at the blood-brain barrier in proton-coupled folate transporter (PCFT) mutant mice.

scientific article published on 4 December 2012

Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice.

scientific article

In vivo activation of human pregnane X receptor tightens the blood-brain barrier to methadone through P-glycoprotein up-regulation

scientific article published on 12 July 2006

In vivo and ex vivo regulation of breast cancer resistant protein (Bcrp) by peroxisome proliferator-activated receptor alpha (Pparα) at the blood-brain barrier

scientific article published on 14 October 2015

Intracellular localization and subsequent redistribution of metal transporters in a rat choroid plexus model following exposure to manganese or iron

scientific journal article

Involvement of guanylyl cyclase and cGMP in the regulation of Mrp2-mediated transport in the proximal tubule

scientific article published on 17 February 2004

Localization of P-gp (Abcb1) and Mrp2 (Abcc2) in freshly isolated rat hepatocytes

scientific article published on 22 October 2007

Lysophosphatidic acid and amitriptyline signal through LPA1R to reduce P-glycoprotein transport at the blood-brain barrier

scientific article published in January 2017

MAC1 mediates LPS-induced production of superoxide by microglia: the role of pattern recognition receptors in dopaminergic neurotoxicity

scientific article published on 01 October 2007

MPP+-induced COX-2 activation and subsequent dopaminergic neurodegeneration.

scientific article published on 21 April 2005

MRP2 and acquired tolerance to inorganic arsenic in the kidney of killifish (Fundulus heteroclitus)

scientific article published on 25 February 2007

Microglial MAC1 receptor and PI3K are essential in mediating β-amyloid peptide-induced microglial activation and subsequent neurotoxicity ⬇️

scientific article published on January 13, 2011

Microglial PHOX and Mac-1 are essential to the enhanced dopaminergic neurodegeneration elicited by A30P and A53T mutant alpha-synuclein.

scientific article published in August 2007

Microglial activation decreases retention of the protease inhibitor saquinavir: implications for HIV treatment

scientific article published on 4 May 2013

Modulation of P-glycoprotein at the blood-brain barrier: opportunities to improve central nervous system pharmacotherapy

scientific article published on 17 June 2008

Modulation of drug transporters at the blood-brain barrier

scientific article published on April 2004

Modulation of p-glycoprotein transport function at the blood-brain barrier

scientific article

Mrp1 is essential for sphingolipid signaling to p-glycoprotein in mouse blood-brain and blood-spinal cord barriers

scientific article published on 21 November 2012

Multidrug resistance-associated proteins: expression and function in the central nervous system

scientific article

Multiple components of 2,4-dichlorophenoxyacetic acid uptake by rat choroid plexus

scientific article published on 15 June 2005

Neuromelanin activates microglia and induces degeneration of dopaminergic neurons: implications for progression of Parkinson's disease

scientific article

Nrf2 upregulates ATP binding cassette transporter expression and activity at the blood-brain and blood-spinal cord barriers

scientific article

Organic anion transport in choroid plexus from wild-type and organic anion transporter 3 (Slc22a8)-null mice

scientific article published on 23 December 2003

Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na+ gradient

scientific article

PPAR-α, a lipid-sensing transcription factor, regulates blood-brain barrier efflux transporter expression

scientific article published on 18 May 2016

Permeability of porcine blood brain barrier to somatostatin analogues

scientific article

Phototoxicity in human lens epithelial cells promoted by St. John's Wort.

scientific article

Phototoxicity in human retinal pigment epithelial cells promoted by hypericin, a component of St. John's wort

scientific article

Pregnane X receptor up-regulation of P-glycoprotein expression and transport function at the blood-brain barrier

scientific article

Prevention of seizure-induced up-regulation of endothelial P-glycoprotein by COX-2 inhibition

scientific article

Rapid loss of blood-brain barrier P-glycoprotein activity through transporter internalization demonstrated using a novel in situ proteolysis protection assay

scientific article

Rapid modulation of P-glycoprotein-mediated transport at the blood-brain barrier by tumor necrosis factor-alpha and lipopolysaccharide

scientific article published on 8 November 2005

Rapid regulation of P-glycoprotein at the blood-brain barrier by endothelin-1.

scientific article

Rapid, nongenomic stimulation of multidrug resistance protein 2 (Mrp2) activity by glucocorticoids in renal proximal tubule.

scientific article

Rapid, reversible modulation of blood-brain barrier P-glycoprotein transport activity by vascular endothelial growth factor

scientific article

Reactive microgliosis participates in MPP+-induced dopaminergic neurodegeneration: role of 67 kDa laminin receptor.

scientific article published in May 2006

Regulation of ABC efflux transporters at blood-brain barrier in health and neurological disorders

scientific article

Regulation of ABC transporters blood-brain barrier: the good, the bad, and the ugly

scientific article

Regulation of MRP2-mediated transport in shark rectal salt gland tubules

scientific article published in March 2002

Regulation of P-glycoprotein and other ABC drug transporters at the blood-brain barrier

scientific article

Relevance of multidrug resistance proteins for intestinal drug absorption in vitro and in vivo

scientific article

Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-beta in a mouse model of Alzheimer's disease

scientific article

Retention of structural and functional polarity in cultured skate hepatocytes undergoing in vitro morphogenesis

scientific article published on 6 March 2006

Reversible dimers of the atypical antipsychotic quetiapine inhibit p-glycoprotein-mediated efflux in vitro with increased binding affinity and in situ at the blood-brain barrier.

scientific article published on 07 February 2014

Role of NO in endothelin-regulated drug transport in the renal proximal tubule

scientific article published in March 2002

Seizure-induced up-regulation of P-glycoprotein at the blood-brain barrier through glutamate and cyclooxygenase-2 signaling

scientific article

Selective increase of two ABC drug efflux transporters at the blood–spinal cord barrier suggests induced pharmacoresistance in ALS ⬇️

scientific article published on April 11, 2012

Selective induction of P-glycoprotein at the CNS barriers during symptomatic stage of an ALS animal model

scientific article published on 20 December 2016

Short- and long-term influences of heavy metals on anionic drug efflux from renal proximal tubule.

scientific article published in May 2002

Short-term exposure of renal proximal tubules to gentamicin increases long-term multidrug resistance protein 2 (Abcc2) transport function and reduces nephrotoxicant sensitivity.

scientific article published on 5 August 2005

Signaling pathways that regulate basal ABC transporter activity at the blood- brain barrier

scientific article published on January 2014

Sphingolipid signaling reduces basal P-glycoprotein activity in renal proximal tubule

scientific article published on 02 January 2014

Targeting blood-brain barrier sphingolipid signaling reduces basal P-glycoprotein activity and improves drug delivery to the brain

scientific article

Texas Red transport across rat and dogfish shark (Squalus acanthias) choroid plexus

scientific article published on 23 July 2008

The flounder organic anion transporter fOat has sequence, function, and substrate specificity similarity to both mammalian Oat1 and Oat3.

scientific article published on 20 July 2006

The outdoor air pollution and brain health workshop

journal article published in 2012

The role of A2E in prevention or enhancement of light damage in human retinal pigment epithelial cells

scientific article published in February 2002

The xenobiotic transporter, MRP2, in epithelia from insects, sharks, and the human breast: Implications for health and disease ⬇️

scientific article published on November 1, 2003

Toward eradicating HIV reservoirs in the brain: inhibiting P-glycoprotein at the blood-brain barrier with prodrug abacavir dimers ⬇️

scientific article published on September 9, 2011

Transepithelial organic anion transport by shark choroid plexus

scientific article published on May 2002

Transport of a fluorescent cAMP analog in teleost proximal tubules

scientific article published on 12 September 2007

Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo

scientific article

Tumor necrosis factor alpha and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier

scientific article published on 28 November 2006

Xenobiotic efflux pumps in isolated fish brain capillaries

scientific article published in January 2002

Zinc chloride rapidly stimulates efflux transporters in renal proximal tubules of killifish (Fundulus heteroclitus).

scientific article

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