List of works - Nathan McDannold

500-element ultrasound phased array system for noninvasive focal surgery of the brain: a preliminary rabbit study with ex vivo human skulls.

scientific article published in July 2004

5th International Symposium on Focused Ultrasound: North Bethesda, MD, USA. 28 August- 1 September 2016.

scientific article published on 21 November 2016

A magnetic resonance imaging-compatible, large-scale array for trans-skull ultrasound surgery and therapy

scientific article published in August 2005

Acoustic feedback enables safe and reliable carboplatin delivery across the blood-brain barrier with a clinical focused ultrasound system and improves survival in a rat glioma model

scientific article published on 14 August 2019

Association between tumor architecture derived from generalized Q-space MRI and survival in glioblastoma

scientific article published on 16 March 2017

Blood-brain barrier disruption and delivery of irinotecan in a rat model using a clinical transcranial MRI-guided focused ultrasound system

scientific article published on 29 May 2020

Blood-brain barrier disruption and vascular damage induced by ultrasound bursts combined with microbubbles can be influenced by choice of anesthesia protocol

scientific article

Blood-brain barrier disruption induced by focused ultrasound and circulating preformed microbubbles appears to be characterized by the mechanical index

scientific article

Brain arterioles show more active vesicular transport of blood-borne tracer molecules than capillaries and venules after focused ultrasound-evoked opening of the blood-brain barrier

scientific article

CADD-32. MECHANISMS OF ENHANCED DRUG DELIVERY IN BRAIN TUMORS WITH FOCUSED ULTRASOUND-INDUCED TRANSIENT BLOOD-TUMOR BARRIER DISRUPTION

Can ultrasound contrast agents increase the treatment envelope?

scientific article published on 30 June 2015

Cavitation-enhanced nonthermal ablation in deep brain targets: feasibility in a large animal model.

scientific article

Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles

scientific article published in July 2004

Combined ultrasound and MR imaging to guide focused ultrasound therapies in the brain

scientific article

Controlled ultrasound-induced blood-brain barrier disruption using passive acoustic emissions monitoring

scientific article

Current status and future potential of MRI-guided focused ultrasound surgery

scientific article published on February 2008

Disruption of Vascular Barriers in Tumors and in the Brain.

scientific article published on 30 June 2015

Does the phase of menstrual cycle affect MR-guided focused ultrasound surgery of uterine leiomyomas?

scientific article published in August 2006

Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endothelium

scientific article

Effects of acoustic parameters and ultrasound contrast agent dose on focused-ultrasound induced blood-brain barrier disruption

scientific article

Effects on P-Glycoprotein Expression after Blood-Brain Barrier Disruption Using Focused Ultrasound and Microbubbles

scientific article

Enhancement in blood-tumor barrier permeability and delivery of liposomal doxorubicin using focused ultrasound and microbubbles: evaluation during tumor progression in a rat glioma model

scientific article

Evaluation of permeability, doxorubicin delivery, and drug retention in a rat brain tumor model after ultrasound-induced blood-tumor barrier disruption

scientific article published on 11 October 2016

Evaluation of referenceless thermometry in MRI-guided focused ultrasound surgery of uterine fibroids

scientific article published on October 2008

Evaluation of three-dimensional temperature distributions produced by a low-frequency transcranial focused ultrasound system within ex vivo human skulls

scientific article

Evolution of Movement Disorders Surgery Leading to Contemporary Focused Ultrasound Therapy for Tremor

scientific article

Focal beam distortion and treatment planning in abdominal focused ultrasound surgery

scientific article published in May 2005

Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery

scientific article

Focused ultrasound induced opening of the blood-brain barrier disrupts inter-hemispheric resting state functional connectivity in the rat brain

scientific article published on 29 May 2018

Heat-activated liposomal MR contrast agent: initial in vivo results in rabbit liver and kidney

scientific article published on 5 February 2004

Image guided focused ultrasound: development of a comprehensive treatment planning, monitoring and control, and assessment.

scientific article published on 30 June 2015

Image-guided thermal therapy of uterine fibroids

scientific article

Improved Anti-Tumor Effect of Liposomal Doxorubicin After Targeted Blood-Brain Barrier Disruption by MRI-Guided Focused Ultrasound in Rat Glioma ⬇️

scientific article published on July 19, 2012

Induction of apoptosis in vivo in the rabbit brain with focused ultrasound and Optison

scientific article published in December 2006

Integrated ultrasound and magnetic resonance imaging for simultaneous temperature and cavitation monitoring during focused ultrasound therapies

scientific article

International Society for Therapeutic Ultrasound Conference 2016: Tel Aviv, Israel. 14-18 March, 2016.

scientific article published on 17 March 2017

Intraoperative magnetic resonance imaging and magnetic resonance imaging-guided therapy for brain tumors

scientific article

Local and reversible blood-brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications

scientific article

MR imaging-controlled focused ultrasound ablation: a noninvasive image-guided surgery

scientific article

MR imaging-guided focused ultrasound surgery of uterine leiomyomas: a feasibility study

scientific article published in March 2003

MRI Monitoring and Quantification of Ultrasound-Mediated Delivery of Liposomes Dually Labeled with Gadolinium and Fluorophore through the Blood-Brain Barrier

scientific article published on 19 April 2019

MRI investigation of the threshold for thermally induced blood-brain barrier disruption and brain tissue damage in the rabbit brain

scientific article published in May 2004

MRI monitoring of heating produced by ultrasound absorption in the skull: in vivo study in pigs

scientific article published in May 2004

MRI-based thermal dosimetry and diffusion-weighted imaging of MRI-guided focused ultrasound thermal ablation of uterine fibroids.

scientific article published on February 2009

MRI-guided focused ultrasound surgery in the brain: tests in a primate model.

scientific article

MRI-guided targeted blood-brain barrier disruption with focused ultrasound: histological findings in rabbits

scientific article

MRI-guided ultrasonic heating allows spatial control of exogenous luciferase in canine prostate

scientific article

Magnetic resonance acoustic radiation force imaging

scientific article

Mechanisms of enhanced drug delivery in brain metastases with focused ultrasound-induced blood-tumor barrier disruption

scientific article published on 27 August 2018

Modulation of brain function by targeted delivery of GABA through the disrupted blood-brain barrier

scientific article published on 16 January 2019

Multiple sessions of liposomal doxorubicin and focused ultrasound mediated blood-brain barrier disruption: safety study.

scientific article published on 30 June 2015

Multiple sessions of liposomal doxorubicin delivery via focused ultrasound mediated blood-brain barrier disruption: a safety study.

scientific article

Multiple treatments with liposomal doxorubicin and ultrasound-induced disruption of blood-tumor and blood-brain barriers improve outcomes in a rat glioma model

scientific article

Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption

scientific article

Noninvasive thermal ablation of hepatocellular carcinoma by using magnetic resonance imaging-guided focused ultrasound

scientific article published in November 2004

Nonthermal ablation in the rat brain using focused ultrasound and an ultrasound contrast agent: long-term effects

scientific article published on 5 February 2016

Nonthermal ablation with microbubble-enhanced focused ultrasound close to the optic tract without affecting nerve function

scientific article

Observed Effects of Whole-Brain Radiation Therapy on Focused Ultrasound Blood-Brain Barrier Disruption

scientific article published on 22 May 2020

Passive Acoustic Mapping with the Angular Spectrum Method.

scientific article published on 21 December 2016

Pre-clinical testing of a phased array ultrasound system for MRI-guided noninvasive surgery of the brain--a primate study.

scientific article

Preclinical evaluation of a low-frequency transcranial MRI-guided focused ultrasound system in a primate model.

scientific article published on 14 October 2016

Progress and problems in the application of focused ultrasound for blood-brain barrier disruption

scientific article

Quality assurance and system stability of a clinical MRI-guided focused ultrasound system: four-year experience

scientific article published in November 2006

Safety Validation of Repeated Blood-Brain Barrier Disruption Using Focused Ultrasound.

scientific article

Secondary effects on brain physiology caused by focused ultrasound-mediated disruption of the blood-brain barrier

scientific article published on 26 May 2020

Targeted delivery of GABA via ultrasound-induced blood-brain barrier disruption blocks somatosensory-evoked potentials.

scientific article published on 30 June 2015

Targeted delivery of antibodies through the blood-brain barrier by MRI-guided focused ultrasound

scientific article

Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI-guided focused ultrasound

scientific article

Targeted, noninvasive blockade of cortical neuronal activity

scientific article

Temperature mapping considerations in the breast with line scan echo planar spectroscopic imaging

scientific article

Temporary disruption of the blood-brain barrier by use of ultrasound and microbubbles: safety and efficacy evaluation in rhesus macaques

scientific article

The Effects of Oxygen on Ultrasound-Induced Blood-Brain Barrier Disruption in Mice

scientific article published on 24 October 2016

The neurovascular response is attenuated by focused ultrasound-mediated disruption of the blood-brain barrier

scientific article published on 11 July 2019

The threshold for brain damage in rabbits induced by bursts of ultrasound in the presence of an ultrasound contrast agent (Optison®) ⬇️

scientific article published on March 1, 2003

The use of quantitative temperature images to predict the optimal power for focused ultrasound surgery: in vivo verification in rabbit muscle and brain

scientific article published on 01 March 2002

Three-year follow-up of prospective trial of focused ultrasound thalamotomy for essential tremor

scientific article published on 20 November 2019

Transcranial Assessment and Visualization of Acoustic Cavitation: Modeling and Experimental Validation

scientific article

Transcranial magnetic resonance imaging- guided focused ultrasound surgery of brain tumors: initial findings in 3 patients

scientific article

Ultrasound-induced suppression of visually-evoked potentials: experience in nonhuman primates with a clinical transcranial MRI-guided focused ultrasound system.

scientific article published on 30 June 2015

Ultrasound-mediated blood-brain barrier disruption for targeted drug delivery in the central nervous system

scientific article

Ultrasound-mediated blood‐brain/blood-tumor barrier disruption improves outcomes with trastuzumab in a breast cancer brain metastasis model ⬇️

scientific article published on September 18, 2012

Update on Clinical Magnetic Resonance-Guided Focused Ultrasound Applications

scientific article

Use of ultrasound pulses combined with Definity for targeted blood-brain barrier disruption: a feasibility study

scientific article

Uterine leiomyomas: MR imaging-based thermometry and thermal dosimetry during focused ultrasound thermal ablation

scientific article

Volumetric analysis of magnetic resonance-guided focused ultrasound thalamotomy lesions

scientific article published in February 2018

“Non-thermal” ablation using focused ultrasound and an ultrasound contrast agent.

scientific article published on 30 June 2015

List of works by Nathan McDannold

500-element ultrasound phased array system for noninvasive focal surgery of the brain: a preliminary rabbit study with ex vivo human skulls.

5th International Symposium on Focused Ultrasound: North Bethesda, MD, USA. 28 August- 1 September 2016.

A magnetic resonance imaging-compatible, large-scale array for trans-skull ultrasound surgery and therapy

Acoustic feedback enables safe and reliable carboplatin delivery across the blood-brain barrier with a clinical focused ultrasound system and improves survival in a rat glioma model

Association between tumor architecture derived from generalized Q-space MRI and survival in glioblastoma

Blood-brain barrier disruption and delivery of irinotecan in a rat model using a clinical transcranial MRI-guided focused ultrasound system

Blood-brain barrier disruption and vascular damage induced by ultrasound bursts combined with microbubbles can be influenced by choice of anesthesia protocol

Blood-brain barrier disruption induced by focused ultrasound and circulating preformed microbubbles appears to be characterized by the mechanical index

Brain arterioles show more active vesicular transport of blood-borne tracer molecules than capillaries and venules after focused ultrasound-evoked opening of the blood-brain barrier

CADD-32. MECHANISMS OF ENHANCED DRUG DELIVERY IN BRAIN TUMORS WITH FOCUSED ULTRASOUND-INDUCED TRANSIENT BLOOD-TUMOR BARRIER DISRUPTION

Can ultrasound contrast agents increase the treatment envelope?

Cavitation-enhanced nonthermal ablation in deep brain targets: feasibility in a large animal model.

Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles

Combined ultrasound and MR imaging to guide focused ultrasound therapies in the brain

Controlled ultrasound-induced blood-brain barrier disruption using passive acoustic emissions monitoring

Current status and future potential of MRI-guided focused ultrasound surgery

Disruption of Vascular Barriers in Tumors and in the Brain.

Does the phase of menstrual cycle affect MR-guided focused ultrasound surgery of uterine leiomyomas?

Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endothelium

Effects of acoustic parameters and ultrasound contrast agent dose on focused-ultrasound induced blood-brain barrier disruption

Effects on P-Glycoprotein Expression after Blood-Brain Barrier Disruption Using Focused Ultrasound and Microbubbles

Enhancement in blood-tumor barrier permeability and delivery of liposomal doxorubicin using focused ultrasound and microbubbles: evaluation during tumor progression in a rat glioma model

Evaluation of permeability, doxorubicin delivery, and drug retention in a rat brain tumor model after ultrasound-induced blood-tumor barrier disruption

Evaluation of referenceless thermometry in MRI-guided focused ultrasound surgery of uterine fibroids

Evaluation of three-dimensional temperature distributions produced by a low-frequency transcranial focused ultrasound system within ex vivo human skulls

Evolution of Movement Disorders Surgery Leading to Contemporary Focused Ultrasound Therapy for Tremor

Focal beam distortion and treatment planning in abdominal focused ultrasound surgery

Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery

Focused ultrasound induced opening of the blood-brain barrier disrupts inter-hemispheric resting state functional connectivity in the rat brain

Heat-activated liposomal MR contrast agent: initial in vivo results in rabbit liver and kidney

Image guided focused ultrasound: development of a comprehensive treatment planning, monitoring and control, and assessment.

Image-guided thermal therapy of uterine fibroids

Improved Anti-Tumor Effect of Liposomal Doxorubicin After Targeted Blood-Brain Barrier Disruption by MRI-Guided Focused Ultrasound in Rat Glioma ⬇️

Induction of apoptosis in vivo in the rabbit brain with focused ultrasound and Optison

Integrated ultrasound and magnetic resonance imaging for simultaneous temperature and cavitation monitoring during focused ultrasound therapies

International Society for Therapeutic Ultrasound Conference 2016: Tel Aviv, Israel. 14-18 March, 2016.

Intraoperative magnetic resonance imaging and magnetic resonance imaging-guided therapy for brain tumors

Local and reversible blood-brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications

MR imaging-controlled focused ultrasound ablation: a noninvasive image-guided surgery

MR imaging-guided focused ultrasound surgery of uterine leiomyomas: a feasibility study

MRI Monitoring and Quantification of Ultrasound-Mediated Delivery of Liposomes Dually Labeled with Gadolinium and Fluorophore through the Blood-Brain Barrier

MRI investigation of the threshold for thermally induced blood-brain barrier disruption and brain tissue damage in the rabbit brain

MRI monitoring of heating produced by ultrasound absorption in the skull: in vivo study in pigs

MRI-based thermal dosimetry and diffusion-weighted imaging of MRI-guided focused ultrasound thermal ablation of uterine fibroids.

MRI-guided focused ultrasound surgery in the brain: tests in a primate model.

MRI-guided targeted blood-brain barrier disruption with focused ultrasound: histological findings in rabbits

MRI-guided ultrasonic heating allows spatial control of exogenous luciferase in canine prostate

Magnetic resonance acoustic radiation force imaging

Mechanisms of enhanced drug delivery in brain metastases with focused ultrasound-induced blood-tumor barrier disruption

Modulation of brain function by targeted delivery of GABA through the disrupted blood-brain barrier

Multiple sessions of liposomal doxorubicin and focused ultrasound mediated blood-brain barrier disruption: safety study.

Multiple sessions of liposomal doxorubicin delivery via focused ultrasound mediated blood-brain barrier disruption: a safety study.

Multiple treatments with liposomal doxorubicin and ultrasound-induced disruption of blood-tumor and blood-brain barriers improve outcomes in a rat glioma model

Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption

Noninvasive thermal ablation of hepatocellular carcinoma by using magnetic resonance imaging-guided focused ultrasound

Nonthermal ablation in the rat brain using focused ultrasound and an ultrasound contrast agent: long-term effects

Nonthermal ablation with microbubble-enhanced focused ultrasound close to the optic tract without affecting nerve function

Observed Effects of Whole-Brain Radiation Therapy on Focused Ultrasound Blood-Brain Barrier Disruption

Passive Acoustic Mapping with the Angular Spectrum Method.

Pre-clinical testing of a phased array ultrasound system for MRI-guided noninvasive surgery of the brain--a primate study.

Preclinical evaluation of a low-frequency transcranial MRI-guided focused ultrasound system in a primate model.

Progress and problems in the application of focused ultrasound for blood-brain barrier disruption

Quality assurance and system stability of a clinical MRI-guided focused ultrasound system: four-year experience

Safety Validation of Repeated Blood-Brain Barrier Disruption Using Focused Ultrasound.

Secondary effects on brain physiology caused by focused ultrasound-mediated disruption of the blood-brain barrier

Targeted delivery of GABA via ultrasound-induced blood-brain barrier disruption blocks somatosensory-evoked potentials.

Targeted delivery of antibodies through the blood-brain barrier by MRI-guided focused ultrasound

Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI-guided focused ultrasound

Targeted, noninvasive blockade of cortical neuronal activity

Temperature mapping considerations in the breast with line scan echo planar spectroscopic imaging

Temporary disruption of the blood-brain barrier by use of ultrasound and microbubbles: safety and efficacy evaluation in rhesus macaques

The Effects of Oxygen on Ultrasound-Induced Blood-Brain Barrier Disruption in Mice

The neurovascular response is attenuated by focused ultrasound-mediated disruption of the blood-brain barrier

The threshold for brain damage in rabbits induced by bursts of ultrasound in the presence of an ultrasound contrast agent (Optison®) ⬇️

The use of quantitative temperature images to predict the optimal power for focused ultrasound surgery: in vivo verification in rabbit muscle and brain

Three-year follow-up of prospective trial of focused ultrasound thalamotomy for essential tremor

Transcranial Assessment and Visualization of Acoustic Cavitation: Modeling and Experimental Validation

Transcranial magnetic resonance imaging- guided focused ultrasound surgery of brain tumors: initial findings in 3 patients

Ultrasound-induced suppression of visually-evoked potentials: experience in nonhuman primates with a clinical transcranial MRI-guided focused ultrasound system.