List of works - Gianluca Degliesposti

A computational workflow for the design of irreversible inhibitors of protein kinases.

scientific article published on 21 March 2010

Activation of the Endonuclease that Defines mRNA 3' Ends Requires Incorporation into an 8-Subunit Core Cleavage and Polyadenylation Factor Complex

scientific article published on 05 February 2019

Architecture of eukaryotic mRNA 3'-end processing machinery

scientific article

Architecture of the mycobacterial type VII secretion system

scientific article published on 09 October 2019

Atomic structure of the entire mammalian mitochondrial complex I.

scientific article

Author Correction: RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex

scientific article published in Nature Communications

BEAR, a novel virtual screening methodology for drug discovery.

scientific article

Binding estimation after refinement, a new automated procedure for the refinement and rescoring of docked ligands in virtual screening

scientific article published in March 2009

Crystal structure of the N-terminal domain of human Timeless and its interaction with Tipin

scientific article published on 25 February 2017

Crystal structure of the N-terminal domain of human Timeless and its interaction with Tipin

scientific article published on 01 January 2020

Design and discovery of plasmepsin II inhibitors using an automated workflow on large-scale grids.

scientific article published on July 2009

Exploring the binding site of C-terminal hsp90 inhibitors

scientific article published on 01 September 2010

Fast and accurate predictions of binding free energies using MM-PBSA and MM-GBSA.

scientific article published in March 2010

First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study

scientific article published on 22 May 2019

In vitro effects of Plasmodium falciparum dihydrofolate reductase inhibitors on normal and cancer cell proliferation.

scientific article published on March 2008

Inter-membrane association of the Sec and BAM translocons for bacterial outer-membrane biogenesis

scientific article published on 04 November 2020

Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells

scientific article published on 25 April 2024

Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch

scientific article published on 01 December 2020

Purification of Ovine Respiratory Complex I Results in a Highly Active and Stable Preparation

scientific article published on 26 September 2016

RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex

scientific article published on 16 April 2018

Structural models and binding site prediction of the C-terminal domain of human Hsp90: a new target for anticancer drugs

scientific article published on 25 March 2008

Structure of the Fanconi anaemia monoubiquitin ligase complex

scientific article published on 30 October 2019

Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone

scientific article

Structures of Respiratory Supercomplex I+III2 Reveal Functional and Conformational Crosstalk

scientific article published on 03 September 2019

The Structure of the R2TP Complex Defines a Platform for Recruiting Diverse Client Proteins to the HSP90 Molecular Chaperone System

scientific article

Validation of an automated procedure for the prediction of relative free energies of binding on a set of aldose reductase inhibitors

scientific article

WISDOM-II: screening against multiple targets implicated in malaria using computational grid infrastructures

scientific article

List of works by Gianluca Degliesposti

A computational workflow for the design of irreversible inhibitors of protein kinases.

Activation of the Endonuclease that Defines mRNA 3' Ends Requires Incorporation into an 8-Subunit Core Cleavage and Polyadenylation Factor Complex

Architecture of eukaryotic mRNA 3'-end processing machinery

Architecture of the mycobacterial type VII secretion system

Atomic structure of the entire mammalian mitochondrial complex I.

Author Correction: RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex

BEAR, a novel virtual screening methodology for drug discovery.

Binding estimation after refinement, a new automated procedure for the refinement and rescoring of docked ligands in virtual screening

Crystal structure of the N-terminal domain of human Timeless and its interaction with Tipin

Crystal structure of the N-terminal domain of human Timeless and its interaction with Tipin

Design and discovery of plasmepsin II inhibitors using an automated workflow on large-scale grids.

Exploring the binding site of C-terminal hsp90 inhibitors

Fast and accurate predictions of binding free energies using MM-PBSA and MM-GBSA.

First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study

In vitro effects of Plasmodium falciparum dihydrofolate reductase inhibitors on normal and cancer cell proliferation.

Inter-membrane association of the Sec and BAM translocons for bacterial outer-membrane biogenesis

Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells

Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch

Purification of Ovine Respiratory Complex I Results in a Highly Active and Stable Preparation

RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex

Structural models and binding site prediction of the C-terminal domain of human Hsp90: a new target for anticancer drugs

Structure of the Fanconi anaemia monoubiquitin ligase complex

Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone

Structures of Respiratory Supercomplex I+III2 Reveal Functional and Conformational Crosstalk

The Structure of the R2TP Complex Defines a Platform for Recruiting Diverse Client Proteins to the HSP90 Molecular Chaperone System

Validation of an automated procedure for the prediction of relative free energies of binding on a set of aldose reductase inhibitors

WISDOM-II: screening against multiple targets implicated in malaria using computational grid infrastructures