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List of works by Lauralyn McIntyre

7 versus 14 days of antibiotic treatment for critically ill patients with bloodstream infection: a pilot randomized clinical trial

scientific article published on 17 February 2018

A Randomized Controlled Trial of Corticosteroids in Pediatric Septic Shock: A Pilot Feasibility Study.

scientific article published on 12 April 2017

A Systematic Review of the Impact of Surgical Special Care Units on Patient Outcomes and Health Care Resource Utilization

scientific article published on 01 March 2019

A pilot randomized controlled trial of 7 versus 14 days of antibiotic treatment for bloodstream infection on non-intensive care versus intensive care wards

scientific article published on 15 January 2020

A systematic review of pediatric clinical trials of high dose vitamin D.

scientific article

Age of transfused blood in critically ill adults

scientific article published on 17 March 2015

Ancillary testing for diagnosis of brain death: a protocol for a systematic review and meta-analysis

scientific article

Anemia prevalence and incidence and red blood cell transfusion practices in aneurysmal subarachnoid hemorrhage: results of a multicenter cohort study.

scientific article published on 4 July 2018

Assessment of Circulating LncRNAs Under Physiologic and Pathologic Conditions in Humans Reveals Potential Limitations as Biomarkers.

scientific article

Assessment of safety and efficacy of mesenchymal stromal cell therapy in preclinical models of acute myocardial infarction: a systematic review protocol

scientific article published on 7 November 2017

Association of hydroxyethyl starch administration with mortality and acute kidney injury in critically ill patients requiring volume resuscitation: a systematic review and meta-analysis

scientific article

Audit and feedback to improve laboratory test and transfusion ordering in critical care: a systematic review

scientific article published on 19 June 2020

Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness (BALANCE): study protocol for a pilot randomized controlled trial

scientific article published on 18 April 2015

Blood component transfusion in critically ill patients.

scientific article published on August 2013

Caloric intake and the fat-to-carbohydrate ratio in hypercapnic acute respiratory failure: Post-hoc analysis of the PermiT trial

scientific article published on 13 November 2018

Cell therapy with intravascular administration of mesenchymal stromal cells continues to appear safe: An updated systematic review and meta-analysis

scientific article published on 17 January 2020

Choice of crystalloid fluid in the treatment of hyperglycemic emergencies: a systematic review protocol

scientific article published on 03 September 2019

Clinical Studies of Ex Vivo Expansion to Accelerate Engraftment After Umbilical Cord Blood Transplantation: A Systematic Review

scientific article

Clinical effects of blood donor characteristics in transfusion recipients: protocol of a framework to study the blood donor-recipient continuum

scientific article

Comparison of Consent Models in a Randomized Trial of Corticosteroids in Pediatric Septic Shock

scientific article

Comparison of crystalloid resuscitation fluids for treatment of acute brain injury: a clinical and pre-clinical systematic review and network meta-analysis protocol

scientific article published on 17 August 2018

Comparison of freshly cultured versus freshly thawed (cryopreserved) mesenchymal stem cells in preclinical in vivo models of inflammation: a protocol for a preclinical systematic review and meta-analysis

scientific article published on 19 August 2020

Comparison of standard and accelerated initiation of renal replacement therapy in acute kidney injury.

scientific article published on 8 July 2015

Continuous multi-parameter heart rate variability analysis heralds onset of sepsis in adults

scientific article

Cost-effectiveness of dalteparin vs unfractionated heparin for the prevention of venous thromboembolism in critically ill patients

scientific article

Critically ill patients with 2009 influenza A(H1N1) infection in Canada

scientific article published on 12 October 2009

Design of nutrition trials in critically ill patients: food for thought.

scientific article published on May 2016

Developing a framework for the ethical design and conduct of pragmatic trials in healthcare: a mixed methods research protocol

article

Do heart and respiratory rate variability improve prediction of extubation outcomes in critically ill patients?

scientific article

Do patient-reported outcome measures for SAH include patient, family, and caregiver priorities? A scoping review

scientific article published on 09 January 2019

Duration of Antimicrobial Treatment for Bacteremia in Canadian Critically Ill Patients

scientific article published on 22 October 2015

Economic evaluation of the prophylaxis for thromboembolism in critical care trial (E-PROTECT): study protocol for a randomized controlled trial

scientific article published on 20 December 2014

Effect of Blood Donor Characteristics on Transfusion Outcomes: A Systematic Review and Meta-Analysis

scientific article

Effect of blood donor characteristics on transfusion outcomes: a protocol for systematic review and meta-analysis.

scientific article published on 20 March 2014

Effect of intravenous immunoglobulins in critically ill adults with sepsis: a meta-analysis

scientific article published on 01 April 2006

Efficacy and safety of mesenchymal stromal cells in preclinical models of acute lung injury: a systematic review protocol.

scientific article

Efficacy and safety of regenerative cell therapy for pulmonary arterial hypertension in animal models: a preclinical systematic review protocol

scientific article published on 25 May 2016

Enriched administrative data can be used to retrospectively identify all known cases of primary subarachnoid hemorrhage.

scientific article

Epidemiology and management of atrial fibrillation in medical and noncardiac surgical adult intensive care unit patients ⬇️

scientific article published on January 4, 2012

Erratum to: Do heart and respiratory rate variability improve prediction of extubation outcomes in critically ill patients?

scientific article published on 2 December 2014

Erythropoietin-receptor agonists in critically ill patients: a meta-analysis of randomized controlled trials

scientific article published on 5 September 2007

Evaluating mesenchymal stem cell therapy for sepsis with preclinical meta-analyses prior to initiating a first-in-human trial

scientific article

Evidence-based emergency medicine/systematic review abstract. Albumin administration in the management of critically ill patients: is it safe?

scientific article published on 23 September 2008

FLUID trial: a protocol for a hospital-wide open-label cluster crossover pragmatic comparative effectiveness randomised pilot trial

Failure of anticoagulant thromboprophylaxis: risk factors in medical-surgical critically ill patients*.

scientific article published on February 2015

Haemoperfusion should only be used for COVID-19 in the context of randomized trials

scientific article published on 08 September 2020

Hemoglobin thresholds and red blood cell transfusion in adult patients with moderate or severe traumatic brain injuries: A retrospective cohort study.

scientific article published on 31 January 2018

Heparin-induced thrombocytopenia in medical surgical critical illness

scientific article

Heparin-induced thrombocytopenia in the critically ill: interpreting the 4Ts test in a randomized trial

scientific article

Impact of balanced versus unbalanced fluid resuscitation on clinical outcomes in critically ill children: protocol for a systematic review and meta-analysis

scientific article published on 05 August 2019

Incidence of postintubation hemodynamic instability associated with emergent intubations performed outside the operating room: a systematic review

scientific article published on January 2014

Informed Consent Documents Used in Critical Care Trials Often Do Not Implement Recommendations

scientific article published on 28 October 2017

Intensive insulin therapy and starch (HES 200/0.5) had some risk and no clear benefit in severe sepsis

scientific article published on 01 June 2008

Interventions to prevent hemodynamic instability during renal replacement therapy for acute kidney injury: a systematic review protocol

scientific article

Interventions to prevent hemodynamic instability during renal replacement therapy in critically ill patients: a systematic review.

scientific article published on 22 February 2018

Is a restrictive transfusion strategy safe for resuscitated and critically ill trauma patients?

scientific article published in September 2004

Is hemoglobin good for cerebral oxygenation and clinical outcome in acute brain injury?

scientific article published on 3 February 2018

Meta-analysis: Intravenous Immunoglobulin in Critically Ill Adult Patients with Sepsis

scientific article published on 01 February 2007

Mortality Risk Profiles for Sepsis: A Novel Longitudinal and Multivariable Approach

scientific article published on 01 August 2019

Multicountry survey of emergency and critical care medicine physicians' fluid resuscitation practices for adult patients with early septic shock

scientific article published on 07 July 2016

Neuromuscular blocking agents in acute respiratory distress syndrome: updated systematic review and meta-analysis of randomized trials

scientific article published on 23 October 2020

Nonleg venous thrombosis in critically ill adults: a nested prospective cohort study

scientific article published on May 2014

Pathogens and antimicrobial susceptibility profiles in critically ill patients with bloodstream infections: a descriptive study

scientific article published on 13 October 2016

Pentastarch resuscitation in severe sepsis and septic shock

scientific article published in January 2010

Permissive Underfeeding or Standard Enteral Feeding in Critically Ill Adults

scientific article

Permissive Underfeeding or Standard Enteral Feeding in High- and Low-Nutritional-Risk Critically Ill Adults. Post Hoc Analysis of the PermiT Trial.

scientific article

Permissive underfeeding versus target enteral feeding in adult critically ill patients (PermiT Trial): a study protocol of a multicenter randomized controlled trial.

scientific article

Poly(I:C) enhances mesenchymal stem cell control of myeloid cells from COVID-19 patients

scientific article published on 01 April 2022

Prevention of post-cardiac surgery vitamin D deficiency in children with congenital heart disease: a pilot feasibility dose evaluation randomized controlled trial

scientific article published on 22 October 2020

Prevention of vitamin D deficiency in children following cardiac surgery: study protocol for a randomized controlled trial

scientific article

Probiotics: Prevention of Severe Pneumonia and Endotracheal Colonization Trial-PROSPECT: a pilot trial

scientific article published on 02 August 2016

Protocol management of severe traumatic brain injury in intensive care units: a systematic review.

scientific article published on February 2013

Random serum free cortisol and total cortisol measurements in pediatric septic shock

scientific article published on 01 July 2018

Rapid normalization of vitamin D levels: a meta-analysis

scientific article

Red blood cell transfusion and mortality effect in aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis protocol.

scientific article

Regenerative cell therapy for pulmonary arterial hypertension in animal models: a systematic review

scientific article published on 06 March 2019

Renal outcomes and mortality following hydroxyethyl starch resuscitation of critically ill patients: systematic review and meta-analysis of randomized trials: ATTENTION: The analysis and conclusions of this article are being revised by the authors.

scientific article published on 27 October 2009

Revisiting transfusion practices in critically ill patients

scientific article

Risk factors and impact of major bleeding in critically ill patients receiving heparin thromboprophylaxis

scientific article published on 14 August 2013

Safety of cell therapy with mesenchymal stromal cells (SafeCell): a systematic review and meta-analysis of clinical trials

scientific article

Saline versus albumin fluid for extracorporeal removal with slow low-efficiency dialysis (SAFER-SLED): study protocol for a pilot trial.

scientific article

Sepsis-Associated Mortality, Resource Use, and Healthcare Costs: A Propensity-Matched Cohort Study

scientific article published on 17 December 2020

Stakeholder views regarding ethical issues in the design and conduct of pragmatic trials: study protocol

scientific article published on 20 November 2018

Standardization of intravenous insulin therapy improves the efficiency and safety of blood glucose control in critically ill adults

scientific article

Steroids in fluid and/or vasoactive infusion dependent pediatric shock: study protocol for a randomized controlled trial

scientific article published on 6 May 2016

Study protocol for a phase II dose evaluation randomized controlled trial of cholecalciferol in critically ill children with vitamin D deficiency (VITdAL-PICU study).

scientific article published on 8 December 2017

Subarachnoid hemorrhage admissions retrospectively identified using a prediction model

scientific article

Substantial variation of both opinions and practice regarding perioperative fluid resuscitation

scientific article published on June 2009

Surrogate Humane Endpoints in Small Animal Models of Acute Lung Injury: A Modified Delphi Consensus Study of Researchers and Laboratory Animal Veterinarians

scientific article published on 16 December 2020

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.

scientific article published on 18 January 2017

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016.

scientific article published on 17 January 2017

Thawed Mesenchymal Stem Cell Product Shows Comparable Immunomodulatory Potency to Cultured Cells In Vitro and in Polymicrobial Septic Animals

scientific article published on 02 December 2019

The Age of Blood Evaluation (ABLE) Randomized Controlled Trial: Study Design ⬇️

scientific article published on May 6, 2011

The Devil Is in the Details: Incomplete Reporting in Preclinical Animal Research.

scientific article

The Effect of Inadequate Initial Empiric Antimicrobial Treatment on Mortality in Critically Ill Patients with Bloodstream Infections: A Multi-Centre Retrospective Cohort Study

scientific article

The Future of Clinical Trials Evaluating Blood Substitutes

scientific article published in The Journal of the American Medical Association

The PRECISE RCT: evolution of an early septic shock fluid resuscitation trial

scientific article published on 4 January 2012

The association between platelet transfusions and bleeding in critically ill patients with thrombocytopenia

scientific article published on 31 May 2017

The conundrum of persistent inappropriate use of frozen plasma ⬇️

scientific article published on May 25, 2011

The efficacy and safety of heparin in patients with sepsis: a systematic review and metaanalysis

scientific article

The impact of perioperative red blood cell transfusions in patients undergoing liver resection: a systematic review

scientific article

Transfusion of red blood cells in patients with traumatic brain injuries admitted to Canadian trauma health centres: a multicentre cohort study

scientific article published on 29 March 2017

Transfusion rates vary significantly amongst Canadian medical centres.

scientific article published in June 2005

Trauma Association of Canada Annual Scientific Meeting, Westin Calgary Calgary, Alberta, Apr. 10–11, 2015Outcomes and opportunities for improvement in self-inflicted blunt and penetrating traumaAbdominal compartment syndrome in the childActive nega

scientific article

Treatment of new-onset atrial fibrillation in noncardiac intensive care unit patients: a systematic review of randomized controlled trials.

scientific article published on May 2008

Value of mesenchymal stem cell therapy for patients with septic shock: an early health economic evaluation

scientific article published on 16 October 2020

Vascular progenitor recruitment in critically ill patients with acute kidney injury.

scientific article published in October 2011

Vital signs after cardiac arrest following withdrawal of life-sustaining therapy: a multicenter prospective observational study

scientific article published on November 2014

Vitamin D deficiency in critically ill children: a systematic review and meta-analysis

scientific article published on 23 November 2017

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