List of works - Szczepan Mogilski

Alkyl derivatives of 1,3,5-triazine as histamine H4 receptor ligands

scientific article published on 12 February 2019

Anti-aggregation effect of aroxyalkyl derivatives of 2-methoxyphenylpiperazine is due to their 5-HT2A and α2-adrenoceptor antagonistic properties. A comparison with ketanserin, sarpogrelate, prazosin, yohimbine and ARC239.

scientific article published on 27 October 2017

Anti-inflammatory activity of lipoic acid in mice peritonitis model

Antiallodynic and antihyperalgesic activity of 3-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-dihydrofuran-2-one compared to pregabalin in chemotherapy-induced neuropathic pain in mice.

scientific article published on 12 April 2014

Antiarrhythmic properties of some 1,4-disubstituted piperazine derivatives with α1-adrenoceptor affinities.

scientific article published on 23 October 2013

Antidepressant-like activity of aroxyalkyl derivatives of 2-methoxyphenylpiperazine and evidence for the involvement of serotonin receptor subtypes in their mechanism of action

scientific article published on 29 November 2015

Antinociceptive, anti-inflammatory and smooth muscle relaxant activities of the pyrrolo[3,4-d]pyridazinone derivatives: Possible mechanisms of action

scientific article published on 3 April 2015

Are anti-inflammatory properties of lipoic acid associated with the formation of hydrogen sulfide?

scientific article published in January 2013

Aryl-1,3,5-triazine ligands of histamine H4 receptor attenuate inflammatory and nociceptive response to carrageen, zymosan and lipopolysaccharide

scientific article published on 20 October 2016

Beneficial effects of non-quinazoline α1-adrenolytics on hypertension and altered metabolism in fructose-fed rats. A comparison with prazosin

scientific article published on 13 April 2019

Biofunctional studies of new 2-methoxyphenylpiperazine xanthone derivatives with α₁-adrenolytic properties

scientific article published on 28 October 2014

Bioresearch of New 1<i>H</i>-pyrrolo[3,4-c]pyridine-1,3(2<i>H</i>)-diones

scientific article published on 12 December 2020

Biphenylalkoxyamine Derivatives-Histamine H Receptor Ligands with Butyrylcholinesterase Inhibitory Activity

scientific article published on 11 June 2021

Biphenyloxy-alkyl-piperidine and azepane derivatives as histamine H3 receptor ligands

scientific article published on 29 July 2017

Chemically Homogenous Compounds with Antagonistic Properties at All α1-Adrenoceptor Subtypes but not β1-Adrenoceptor Attenuate Adrenaline-Induced Arrhythmia in Rats

scientific article published on 3 August 2016

Identification of New Compounds with Anticonvulsant and Antinociceptive Properties in a Group of 3-substituted (2,5-dioxo-pyrrolidin-1-yl)(phenyl)-Acetamides

scientific article published on 3 December 2021

Involvement of the NO/sGC/cGMP/K+ channels pathway in vascular relaxation evoked by two non-quinazoline α1-adrenoceptor antagonists.

scientific article

KA-104, a new multitargeted anticonvulsant with potent antinociceptive activity in preclinical models

scientific article published on 14 September 2020

KA-11, a Novel Pyrrolidine-2,5-dione Derived Broad-Spectrum Anticonvulsant: Its Antiepileptogenic, Antinociceptive Properties and in Vitro Characterization

scientific article published on 10 October 2018

KSK19 - Novel histamine H3 receptor ligand reduces body weight in diet induced obese mice

scientific article published on 08 July 2019

Multifunctional Hybrid Compounds Derived from 2-(2,5-Dioxopyrrolidin-1-yl)-3-methoxypropanamides with Anticonvulsant and Antinociceptive Properties

scientific article published on 21 September 2017

Multitargeted Compounds Derived from (2,5-Dioxopyrrolidin-1-yl)(phenyl)-Acetamides as Candidates for Effective Anticonvulsant and Antinociceptive Agents

scientific article published on 01 June 2020

Novel naphthyloxy derivatives - Potent histamine H3 receptor ligands. Synthesis and pharmacological evaluation.

scientific article published on 11 April 2018

Optimization and preclinical evaluation of novel histamine H3receptor ligands: Acetyl and propionyl phenoxyalkyl piperazine derivatives

scientific article published on 10 November 2018

Pharmacological evaluation of the anxiolytic-like effects of EMD 386088, a partial 5-HT6 receptor agonist, in the rat elevated plus-maze and Vogel conflict tests.

scientific article published on 4 June 2014

Pharmacophore models based studies on the affinity and selectivity toward 5-HT1A with reference to α1-adrenergic receptors among arylpiperazine derivatives of phenytoin

scientific article published on 05 December 2010

Rational design of new multitarget histamine H3 receptor ligands as potential candidates for treatment of Alzheimer's disease

scientific article published on 21 August 2020

Relaxant effects of selected sildenafil analogues in the rat aorta.

scientific article published on 23 March 2015

Reversal of cardiac, vascular, and renal dysfunction by non-quinazoline α1-adrenolytics in DOCA-salt hypertensive rats: a comparison with prazosin, a quinazoline-based α1-adrenoceptor antagonist

scientific article published on 12 March 2019

Synthesis and activity of newly designed aroxyalkyl or aroxyethoxyethyl derivatives of piperazine on the cardiovascular and the central nervous systems

scientific article published on 15 September 2016

Synthesis and biological activity of novel tert-butyl and tert-pentylphenoxyalkyl piperazine derivatives as histamine H3R ligands

Synthesis and pharmacological evaluation of novel arylpiperazine oxicams derivatives as potent analgesics without ulcerogenicity

scientific article published on 02 March 2019

Synthesis, alpha 1-adrenoceptor antagonist activity, and SAR study of novel arylpiperazine derivatives of phenytoin.

scientific article published on 26 April 2008

The Search for New Anticonvulsants in a Group of (2,5-Dioxopyrrolidin-1-yl)(phenyl)Acetamides with Hybrid Structure-Synthesis and In Vivo/In Vitro Studies

scientific article published on 20 November 2020

The effect of GABA transporter 1 (GAT1) inhibitor, tiagabine, on scopolamine-induced memory impairments in mice.