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List of works by Hazel M Girvan

A single mutation in cytochrome P450 BM3 induces the conformational rearrangement seen upon substrate binding in the wild-type enzyme.

scientific article published on 12 March 2004

Analysis of Heme Iron Coordination in DGCR8: The Heme-Binding Component of the Microprocessor Complex.

scientific article published on 20 August 2016

Analysis of the interactions of cytochrome b5 with flavocytochrome P450 BM3 and its domains.

scientific article published in January 2007

Analysis of the oxidation of short chain alkynes by flavocytochrome P450 BM3

scientific article published on 23 March 2011

Applications of microbial cytochrome P450 enzymes in biotechnology and synthetic biology

scientific article

Biophysical characterization of the sterol demethylase P450 from Mycobacterium tuberculosis, its cognate ferredoxin, and their interactions

scientific journal article

Catalytic Determinants of Alkene Production by the Cytochrome P450 Peroxygenase OleTJE.

scientific article published on 4 January 2017

Characterization of Cytochrome P450 Enzymes and Their Applications in Synthetic Biology

scientific article published on 20 August 2018

Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches

scientific article published on 17 April 2020

Clobetasol Propionate Is a Heme-Mediated Selective Inhibitor of Human Cytochrome P450 3A5

scientific article published on 22 January 2020

Conformational dynamics of the cytochrome P450 BM3/N-palmitoylglycine complex: the proposed "proximal-distal" transition probed by temperature-jump spectroscopy.

scientific article published on 16 June 2007

Cytochrome P450--redox partner fusion enzymes.

scientific article published on 30 August 2006

Cytochrome P450/redox partner fusion enzymes: biotechnological and toxicological prospects

scientific article published on December 2007

Cytochrome P450s: creating novel ligand sets.

scientific article

Expression, Purification, and Biochemical Characterization of the Flavocytochrome P450 CYP505A30 from Myceliophthora thermophila

scientific article published on 18 August 2017

Flavocytochrome P450 BM3 mutant A264E undergoes substrate-dependent formation of a novel heme iron ligand set.

scientific article published on 12 March 2004

Flavocytochrome P450 BM3 mutant W1046A is a NADH-dependent fatty acid hydroxylase: implications for the mechanism of electron transfer in the P450 BM3 dimer

scientific article published on 22 September 2010

Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3

scientific article

Heme and Hemoproteins

scientific article

Heme sensor proteins

scientific article published on 28 March 2013

Interaction of nitric oxide with cytochrome P450 BM3.

scientific article published in December 2004

Laser photoexcitation of NAD(P)H induces reduction of P450 BM3 heme domain on the microsecond time scale

scientific article

Novel haem co-ordination variants of flavocytochrome P450BM3

scientific article

Novel insights into P450 BM3 interactions with FDA-approved antifungal azole drugs

scientific article published in Scientific Reports

Probing the molecular determinants of coenzyme selectivity in the P450 BM3 FAD/NADPH domain

scientific article

Structural Characterization and Ligand/Inhibitor Identification Provide Functional Insights into the Mycobacterium tuberculosis Cytochrome P450 CYP126A1

scientific article (publication date: 27 January 2017)

Structural and catalytic properties of the peroxygenase P450 enzyme CYP152K6 from Bacillus methanolicus

scientific article published on 03 August 2018

Structural and spectroscopic characterization of P450 BM3 mutants with unprecedented P450 heme iron ligand sets. New heme ligation states influence conformational equilibria in P450 BM3.

scientific article published on 31 October 2006

The crystal structure of the FAD/NADPH-binding domain of flavocytochrome P450 BM3

scientific article

The dimeric form of flavocytochrome P450 BM3 is catalytically functional as a fatty acid hydroxylase.

scientific article published on 28 September 2005

Variations on a (t)heme--novel mechanisms, redox partners and catalytic functions in the cytochrome P450 superfamily

scientific article

What makes a P450 tick?

scientific article published on 26 January 2013

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