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List of works by Beth Karlan

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Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013
Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer

scientific article
Periostin secreted by epithelial ovarian carcinoma is a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins and promotes cell motility

scientific article
Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer

scientific article
Gene expression profile of BRCAness that correlates with responsiveness to chemotherapy and with outcome in patients with epithelial ovarian cancer.

scientific article
Salpingo-oophorectomy and the risk of ovarian, fallopian tube, and peritoneal cancers in women with a BRCA1 or BRCA2 Mutation

scientific article
Secondary somatic mutations restoring BRCA1/2 predict chemotherapy resistance in hereditary ovarian carcinomas.

scientific article
GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

scientific article published on April 2013
A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

scientific article
Impact of oophorectomy on cancer incidence and mortality in women with a BRCA1 or BRCA2 mutation

scientific article
Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article
Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

scientific article published on 5 December 2011
Common variants at 19p13 are associated with susceptibility to ovarian cancer

scientific article
Adverse health outcomes in women exposed in utero to diethylstilbestrol

scientific article
Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

scientific article (publication date: 2013)
Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

scientific article
Phase I clinical study of pertuzumab, a novel HER dimerization inhibitor, in patients with advanced cancer

scientific article published on 07 February 2005
Identification of six new susceptibility loci for invasive epithelial ovarian cancer

scientific article published on 12 January 2015
Regulation of miR-200 family microRNAs and ZEB transcription factors in ovarian cancer: evidence supporting a mesothelial-to-epithelial transition

scientific article
Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer

scientific article published on 27 August 2015
Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction

scientific article
Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

scientific article published in 2013
Discovery and preclinical validation of salivary transcriptomic and proteomic biomarkers for the non-invasive detection of breast cancer

scientific article (publication date: 31 December 2010)
Reproductive risk factors for ovarian cancer in carriers of BRCA1 or BRCA2 mutations: a case-control study

article
Tumorgrafts as in vivo surrogates for women with ovarian cancer.

scientific article published on 07 January 2014
Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.

scientific article published on January 2013
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

scientific article
Clinical cancer advances 2008: major research advances in cancer treatment, prevention, and screening--a report from the American Society of Clinical Oncology

scientific article published on 22 December 2008
Rapid progression of prostate cancer in men with a BRCA2 mutation

scientific article published on 24 June 2008
Coexisting ovarian malignancy in young women with endometrial cancer

scientific article
Clinicopathological analysis of endometrial carcinomas harboring somatic POLE exonuclease domain mutations

scientific article
Comprehensive Characterization of Cancer Driver Genes and Mutations

article
Genome-Wide Meta-Analyses of Breast, Ovarian, and Prostate Cancer Association Studies Identify Multiple New Susceptibility Loci Shared by at Least Two Cancer Types

scientific article published in September 2016
Dose-Response Association of CD8+ Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer.

scientific article published on 12 October 2017
Germline mutation in BRCA1 or BRCA2 and ten-year survival for women diagnosed with epithelial ovarian cancer

scientific article
Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

scientific article
Evaluation of MCF10A as a Reliable Model for Normal Human Mammary Epithelial Cells

scientific article published on July 6, 2015
Mutational Spectrum in a Worldwide Study of 29,700 Families with BRCA1 or BRCA2 Mutations

scientific article published on 15 February 2018
A phase II, randomized, placebo-controlled study of vismodegib as maintenance therapy in patients with ovarian cancer in second or third complete remission.

scientific article published on 02 October 2012
The BRCA1-Δ11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin

scientific article published on May 2016
Platinum sensitivity-related germline polymorphism discovered via a cell-based approach and analysis of its association with outcome in ovarian cancer patients

scientific article
Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.

scientific article published on 2 November 2011
Plasma cell-free DNA in ovarian cancer: an independent prognostic biomarker

scientific article
Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriers

scientific article published on 18 May 2011
PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

scientific article published in December 2016
Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.

scientific article
BRCA2 Polymorphic Stop Codon K3326X and the Risk of Breast, Prostate, and Ovarian Cancers

scientific article
Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriers

scientific article
Refined histopathological predictors of BRCA1 and BRCA2 mutation status: a large-scale analysis of breast cancer characteristics from the BCAC, CIMBA, and ENIGMA consortia

scientific article
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer

scientific article published on 27 April 2016

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