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List of works by Spyros A Kalams

A phase IIA randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade rAd5 HIV-1 vaccine boost in healthy adults (HVTN204)

scientific article (publication date: 2011)

Abacavir-reactive memory T cells are present in drug naïve individuals

scientific article

Abnormal Immune Responses in Persons with Previous Extrapulmonary Tuberculosis in anIn VitroModel That SimulatesIn VivoInfection with Mycobacterium tuberculosis ⬇️

scientific article published on June 6, 2012

Association of VH4-59 Antibody Variable Gene Usage with Recognition of an Immunodominant Epitope on the HIV-1 Gag Protein

scientific article published on 30 July 2015

B cell responses to HIV antigen are a potent correlate of viremia in HIV-1 infection and improve with PD-1 blockade

scientific article

Cellular Immunity for Prevention and Clearance of HIV Infection ⬇️

scientific article published on May 1, 2003

Cellular recognition of Mycobacterium tuberculosis ESAT-6 and KatG peptides in systemic sarcoidosis

scientific article published on 6 November 2006

Characteristics of the earliest cross-neutralizing antibody response to HIV-1.

scientific article

Clonal expansion and TCR-independent differentiation shape the HIV-specific CD8+ effector-memory T-cell repertoire in vivo

scientific article

Cocaine enhances HIV-1-induced CD4(+) T-cell apoptosis: implications in disease progression in cocaine-abusing HIV-1 patients.

scientific article published on 31 January 2014

Comparison of overlapping peptide sets for detection of antiviral CD8 and CD4 T cell responses

scientific article published in April 2003

Cytomegalovirus (CMV) Epitope-Specific CD4(+) T Cells Are Inflated in HIV(+) CMV(+) Subjects

scientific article published on 2 October 2017

DNA and Modified Vaccinia Virus Ankara Vaccines Encoding Multiple Cytotoxic and Helper T-Lymphocyte Epitopes of Human Immunodeficiency Virus Type 1 (HIV-1) Are Safe but Weakly Immunogenic in HIV-1-Uninfected, Vaccinia Virus-Naive Adults ⬇️

scientific article published on March 7, 2012

Determinant of HIV-1 mutational escape from cytotoxic T lymphocytes

scientific article

Early CD4+ T Cell Responses Are Associated with Subsequent CD8+ T Cell Responses to an rAd5-Based Prophylactic Prime-Boost HIV Vaccine Strategy

scientific article

Emergence of broadly neutralizing antibodies and viral coevolution in two subjects during the early stages of infection with human immunodeficiency virus type 1

scientific article

Envelope variants circulating as initial neutralization breadth developed in two HIV-infected subjects stimulate multiclade neutralizing antibodies in rabbits.

scientific article

Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infection

scientific article

First-in-Human Evaluation of the Safety and Immunogenicity of a Recombinant Vesicular Stomatitis Virus Human Immunodeficiency Virus-1 gag Vaccine (HVTN 090).

scientific article published on 5 June 2015

Fluctuations of functionally distinct CD8+ T-cell clonotypes demonstrate flexibility of the HIV-specific TCR repertoire

scientific article published on December 2005

HIV-DNA priming alters T cell responses to HIV-adenovirus vaccine even when responses to DNA are undetectable

scientific article

Human Antibodies that Recognize Novel Immunodominant Quaternary Epitopes on the HIV-1 Env Protein

scientific article

Identification of a CCR5-expressing T cell subset that is resistant to R5-tropic HIV infection

scientific article

Impacts of Avidity and Specificity on the Antiviral Efficiency of HIV-1-Specific CTL ⬇️

scientific article published on October 1, 2003

Increased breadth of HIV-1 neutralization achieved by diverse antibody clones each with limited neutralization breadth

scientific article published in PLoS ONE

Increased frequency of regulatory T cells and T lymphocyte activation in persons with previously treated extrapulmonary tuberculosis

scientific article published on 28 October 2011

Kinetic Analysis by Real-Time PCR of Hepatitis C Virus (HCV)-Specific T Cells in Peripheral Blood and Liver after Challenge with HCV

scientific article (publication date: November 2008)

Limited T Cell Receptor Diversity of HCV-specific T Cell Responses Is Associated with CTL Escape

scientific article (publication date: 2 August 2004)

Limited sequence evolution within persistently targeted CD8 epitopes in chronic human immunodeficiency virus type 1 infection

scientific article

Maternal transmission of human immunodeficiency virus escape mutations subverts HLA-B57 immunodominance but facilitates viral control in the haploidentical infant

scientific article published on 10 June 2009

Mitochondrial Genomics and CD4 T-Cell Count Recovery After Antiretroviral Therapy Initiation in AIDS Clinical Trials Group Study 384 ⬇️

scientific article published on December 1, 2011

Mitochondrial Haplogroups as a Risk Factor for Herpes Zoster.

scientific article published on 19 October 2016

Multiparameter analysis of stimulated human peripheral blood mononuclear cells: A comparison of mass and fluorescence cytometry.

scientific article published on 24 November 2015

Mycobacterium tuberculosis Antigen 85A induces Th-1 immune responses in systemic sarcoidosis

scientific article published on 15 March 2007

Neither vaginal nor buccal administration of 800 μg misoprostol alters mucosal and systemic immune activation or the cervicovaginal microbiome: a pilot study.

scientific article

OpenCyto: an open source infrastructure for scalable, robust, reproducible, and automated, end-to-end flow cytometry data analysis

scientific article

Phase 1 safety and immunogenicity testing of DNA and recombinant modified vaccinia Ankara vaccines expressing HIV-1 virus-like particles

scientific article

Phase I/II randomized trial of safety and immunogenicity of LIPO-5 alone, ALVAC-HIV (vCP1452) alone, and ALVAC-HIV (vCP1452) prime/LIPO-5 boost in healthy, HIV-1-uninfected adult participants

scientific article

Postpartum viral load rebound in HIV-1-infected women treated with highly active antiretroviral therapy: AIDS Clinical Trials Group Protocol A5150.

scientific article published on January 2011

Reducing the activity and secretion of microbial antioxidants enhances the immunogenicity of BCG.

scientific article

Safety and Immunogenicity of a Recombinant Adenovirus Serotype 35-Vectored HIV-1 Vaccine in Adenovirus Serotype 5 Seronegative and Seropositive Individuals

scientific article

Safety and Immunogenicity of an HIV-1 Gag DNA Vaccine with or without IL-12 and/or IL-15 Plasmid Cytokine Adjuvant in Healthy, HIV-1 Uninfected Adults ⬇️

scientific article published on January 5, 2012

Safety and comparative immunogenicity of an HIV-1 DNA vaccine in combination with plasmid interleukin 12 and impact of intramuscular electroporation for delivery

scientific article published on 08 July 2013

Safety and immunogenicity of a CTL multiepitope peptide vaccine for HIV with or without GM-CSF in a phase I trial

scientific article

Specificity and 6-month durability of immune responses induced by DNA and recombinant modified vaccinia Ankara vaccines expressing HIV-1 virus-like particles

scientific article

Suppression of HIV-specific and allogeneic T cell activation by human regulatory T cells is dependent on the strength of signals

scientific article

T Cell Activation Markers and African Mitochondrial DNA Haplogroups among Non-Hispanic Black Participants in AIDS Clinical Trials Group Study 384 ⬇️

scientific article published on August 27, 2012

The metabolic and cardiovascular consequences of obesity in persons with HIV on long-term antiretroviral therapy

scientific article

The potential role of epitope-specific T-cell receptor diversity in the control of HIV replication

scientific article published on May 2007

Vaccination With Heterologous HIV-1 Envelope Sequences and Heterologous Adenovirus Vectors Increases T-Cell Responses to Conserved Regions: HVTN 083

scientific article

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