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List of works by Natalia Issaeva

6-thioguanine selectively kills BRCA2-defective tumors and overcomes PARP inhibitor resistance

scientific article

Attenuated TRAF3 Fosters Activation of Alternative NF-κB and Reduced Expression of Antiviral Interferon, TP53, and RB to Promote HPV-Positive Head and Neck Cancers

scientific article published on 19 June 2018

Demethylation therapy as a targeted treatment for human papilloma virus-associated head and neck cancer

scientific article published on 15 September 2017

Downregulation of SMG-1 in HPV-positive head and neck squamous cell carcinoma due to promoter hypermethylation correlates with improved survival.

scientific article

Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.

scientific article

LZAP is a novel Wip1 binding partner and positive regulator of its phosphatase activity in vitro

scientific article published on 27 December 2016

Mutant p53-dependent growth suppression distinguishes PRIMA-1 from known anticancer drugs: a statistical analysis of information in the National Cancer Institute database.

scientific article

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

scientific article (publication date: 30 November 2006)

PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination.

scientific article published on 23 July 2009

Poly(ADP-ribose) polymerase is hyperactivated in homologous recombination-defective cells

scientific article published on 15 June 2010

RPA mediates recombination repair during replication stress and is displaced from DNA by checkpoint signalling in human cells

scientific article

Reactivation of mutant p53 and induction of apoptosis in human tumor cells by maleimide analogs

scientific article published in December 2017

Reactivation of mutant p53 and induction of apoptosis in human tumor cells by maleimide analogs.

scientific article published on July 2005

Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.

scientific article

Reverse-phase protein array profiling of oropharyngeal cancer and significance of PIK3CA mutations in HPV-associated head and neck cancer

scientific article

SMG-1 suppresses CDK2 and tumor growth by regulating both the p53 and Cdc25A signaling pathways

scientific article published on 04 October 2013

TRAF3/CYLD mutations identify a distinct subset of human papillomavirus-associated head and neck squamous cell carcinoma

scientific article

TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior ⬇️

scientific article published on August 8, 2013

Tumor suppressor Lzap regulates cell cycle progression, doming, and zebrafish epiboly ⬇️

scientific article published on April 26, 2011

Tumour suppressor Fus1 provides a molecular link between inflammatory response and mitochondrial homeostasis ⬇️

scientific article published on June 6, 2012

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