List of works - José Luis Jiménez

A Phase I Randomized Therapeutic MVA-B Vaccination Improves the Magnitude and Quality of the T Cell Immune Responses in HIV-1-Infected Subjects on HAART.

scientific article

ACSM4 polymorphisms are associated with rapid AIDS progression in HIV-infected patients

scientific article

Analysis of ALS-related proteins during herpes simplex virus-2 latent infection

scientific article published on 07 December 2020

Anti-Human Immunodeficiency Virus Activity of Thiol-Ene Carbosilane Dendrimers and Their Potential Development as a Topical Microbicide

scientific article published on October 2015

Bryostatin activates HIV-1 latent expression in human astrocytes through a PKC and NF-ĸB-dependent mechanism

scientific article published on 22 July 2015

CCR5+ CD8 T-cell levels and monocyte activation precede the onset of acute coronary syndrome in HIV-infected patients on antiretroviral therapy.

scientific article published on 9 March 2017

CYP27B1 rs10877012 T allele was linked to non-AIDS progression in ART-naïve HIV-infected patients: a retrospective study

scientific article published on 11 September 2020

Carbosilane dendrimers as gene delivery agents for the treatment of HIV infection.

scientific article published on 8 April 2014

Carbosilane dendrons with fatty acids at the core as a new potential microbicide against HSV-2/HIV-1 co-infection

scientific article

Combination of G2-S16 dendrimer/dapivirine antiretroviral as a new HIV-1 microbicide

scientific article published on 11 November 2019

Correction: Safety and vaccine-induced HIV-1 immune responses in healthy volunteers following a late MVA-B boost 4 years after the last immunization.

scientific article

DBP rs16846876 and rs12512631 polymorphisms are associated with progression to AIDS naïve HIV-infected patients: a retrospective study

scientific article published on 23 October 2019

Dendrimers as topical microbicides with activity against HIV

article

Dendronized PLGA nanoparticles with anionic carbosilane dendrons as antiviral agents against HIV infection

article

Dendronized magnetic nanoparticles for HIV-1 capture and rapid diagnostic

scientific article published on 23 May 2019

Dysregulation of the Immune System in HIV/HCV-Coinfected Patients According to Liver Stiffness Status

article

GCN2 has inhibitory effect on human immunodeficiency virus-1 protein synthesis and is cleaved upon viral infection

scientific article

Gold nanoparticles stabilized by cationic carbosilane dendrons: synthesis and biological properties

scientific article

HIV-1 antiviral behavior of anionic PPI metallo-dendrimers with EDA core

scientific article published on 18 May 2015

High Plasma Levels of sTNF-R1 and CCL11 Are Related to CD4+ T-Cells Fall in Human Immunodeficiency Virus Elite Controllers With a Sustained Virologic Control.

scientific article

IL7RA polymorphisms are not associated with AIDS progression

scientific article published on 10 August 2017

In silico search, chemical characterization and immunogenic evaluation of amino-terminated G4-PAMAM-HIV peptide complexes using three-dimensional models of the HIV-1 gp120 protein

scientific article published on 18 January 2019

Increased CD127+ and decreased CD57+ T cell expression levels in HIV-infected patients on NRTI-sparing regimens

scientific article published on 20 December 2017

Lack of association of HIV-1 biological or molecular properties with neurotropism for brain cells

scientific article published on January 2006

Mechanistic Studies of Viral Entry: An Overview of Dendrimer-Based Microbicides As Entry Inhibitors Against Both HIV and HSV-2 Overlapped Infections.

scientific article published on 12 August 2016

Mitochondrial haplogroups are associated with clinical pattern of AIDS progression in HIV-infected patients

scientific article published in June 2013

Mutations at codons 54 and 82 of HIV protease predict virological response of HIV-infected children on salvage lopinavir/ritonavir therapy.

scientific article

Pediatric HIV BioBank: a new role of the Spanish HIV BioBank in pediatric HIV research

scientific article published in February 2010

Polyanionic N-donor ligands as chelating agents in transition metal complexes: synthesis, structural characterization and antiviral properties against HIV

article

Polyanionic carbosilane dendrimer-conjugated antiviral drugs as efficient microbicides: Recent trends and developments in HIV treatment/therapy.

scientific article published on 31 March 2015

Polyanionic carbosilane dendrimers prevent hepatitis C virus infection in cell culture

scientific article published on 22 August 2016

Prevention vaginally of HIV-1 transmission in humanized BLT mice and mode of antiviral action of polyanionic carbosilane dendrimer G2-S16.

scientific article

Promising PEGylated cationic dendrimers for delivery of miRNAs as a possible therapy against HIV-1 infection

scientific article published on 28 May 2021

Reasons for not participating in a phase 1 preventive HIV vaccine study in a resource-rich country

scientific article published on 13 June 2012

Role of toll-like receptor 4 Asp299Gly polymorphism in the development of cardiovascular diseases in HIV-infected patients.

scientific article

Safety and immunogenicity of a modified pox vector-based HIV/AIDS vaccine candidate expressing Env, Gag, Pol and Nef proteins of HIV-1 subtype B (MVA-B) in healthy HIV-1-uninfected volunteers: A phase I clinical trial (RISVAC02).

scientific article published on 09 September 2011

Safety and immunogenicity of a modified vaccinia Ankara-based HIV-1 vaccine (MVA-B) in HIV-1-infected patients alone or in combination with a drug to reactivate latent HIV-1.

scientific article published on 26 February 2015

Safety and vaccine-induced HIV-1 immune responses in healthy volunteers following a late MVA-B boost 4 years after the last immunization.

scientific article published on 24 October 2017

Synergistic activity profile of carbosilane dendrimer G2-STE16 in combination with other dendrimers and antiretrovirals as topical anti-HIV-1 microbicide

scientific article published on 14 October 2013

Synthesis of new anionic carbosilane dendrimers via thiol-ene chemistry and their antiviral behaviour

scientific article published on 14 April 2014

Synthesis, structure and molecular modelling of anionic carbosilane dendrimers.

scientific article

The HIV/AIDS vaccine candidate MVA-B administered as a single immunogen in humans triggers robust, polyfunctional, and selective effector memory T cell responses to HIV-1 antigens.

scientific article published on 24 August 2011

The Spanish HIV BioBank: a model of cooperative HIV research

scientific article

Triple combination of carbosilane dendrimers, tenofovir and maraviroc as potential microbicide to prevent HIV-1 sexual transmission

scientific article published on January 2015

Vector replication and expression of HIV-1 antigens by the HIV/AIDS vaccine candidate MVA-B is not affected by HIV-1 protease inhibitors

scientific article

Virological phenotype switches under salvage therapy with lopinavir-ritonavir in heavily pretreated HIV-1 vertically infected children.

scientific article published in January 2004

rs2228570 Polymorphism Is Related to Non-Progression to AIDS in Antiretroviral Therapy Naïve HIV-Infected Patients

article

List of works by José Luis Jiménez

A Phase I Randomized Therapeutic MVA-B Vaccination Improves the Magnitude and Quality of the T Cell Immune Responses in HIV-1-Infected Subjects on HAART.

ACSM4 polymorphisms are associated with rapid AIDS progression in HIV-infected patients

Analysis of ALS-related proteins during herpes simplex virus-2 latent infection

Anti-Human Immunodeficiency Virus Activity of Thiol-Ene Carbosilane Dendrimers and Their Potential Development as a Topical Microbicide

Bryostatin activates HIV-1 latent expression in human astrocytes through a PKC and NF-ĸB-dependent mechanism

CCR5+ CD8 T-cell levels and monocyte activation precede the onset of acute coronary syndrome in HIV-infected patients on antiretroviral therapy.

CYP27B1 rs10877012 T allele was linked to non-AIDS progression in ART-naïve HIV-infected patients: a retrospective study

Carbosilane dendrimers as gene delivery agents for the treatment of HIV infection.

Carbosilane dendrons with fatty acids at the core as a new potential microbicide against HSV-2/HIV-1 co-infection

Combination of G2-S16 dendrimer/dapivirine antiretroviral as a new HIV-1 microbicide

Correction: Safety and vaccine-induced HIV-1 immune responses in healthy volunteers following a late MVA-B boost 4 years after the last immunization.

DBP rs16846876 and rs12512631 polymorphisms are associated with progression to AIDS naïve HIV-infected patients: a retrospective study

Dendrimers as topical microbicides with activity against HIV

Dendronized PLGA nanoparticles with anionic carbosilane dendrons as antiviral agents against HIV infection

Dendronized magnetic nanoparticles for HIV-1 capture and rapid diagnostic

Dysregulation of the Immune System in HIV/HCV-Coinfected Patients According to Liver Stiffness Status

GCN2 has inhibitory effect on human immunodeficiency virus-1 protein synthesis and is cleaved upon viral infection

Gold nanoparticles stabilized by cationic carbosilane dendrons: synthesis and biological properties

HIV-1 antiviral behavior of anionic PPI metallo-dendrimers with EDA core

High Plasma Levels of sTNF-R1 and CCL11 Are Related to CD4+ T-Cells Fall in Human Immunodeficiency Virus Elite Controllers With a Sustained Virologic Control.

IL7RA polymorphisms are not associated with AIDS progression

In silico search, chemical characterization and immunogenic evaluation of amino-terminated G4-PAMAM-HIV peptide complexes using three-dimensional models of the HIV-1 gp120 protein

Increased CD127+ and decreased CD57+ T cell expression levels in HIV-infected patients on NRTI-sparing regimens

Lack of association of HIV-1 biological or molecular properties with neurotropism for brain cells

Mechanistic Studies of Viral Entry: An Overview of Dendrimer-Based Microbicides As Entry Inhibitors Against Both HIV and HSV-2 Overlapped Infections.

Mitochondrial haplogroups are associated with clinical pattern of AIDS progression in HIV-infected patients

Mutations at codons 54 and 82 of HIV protease predict virological response of HIV-infected children on salvage lopinavir/ritonavir therapy.

Pediatric HIV BioBank: a new role of the Spanish HIV BioBank in pediatric HIV research

Polyanionic N-donor ligands as chelating agents in transition metal complexes: synthesis, structural characterization and antiviral properties against HIV

Polyanionic carbosilane dendrimer-conjugated antiviral drugs as efficient microbicides: Recent trends and developments in HIV treatment/therapy.

Polyanionic carbosilane dendrimers prevent hepatitis C virus infection in cell culture

Prevention vaginally of HIV-1 transmission in humanized BLT mice and mode of antiviral action of polyanionic carbosilane dendrimer G2-S16.

Promising PEGylated cationic dendrimers for delivery of miRNAs as a possible therapy against HIV-1 infection

Reasons for not participating in a phase 1 preventive HIV vaccine study in a resource-rich country

Role of toll-like receptor 4 Asp299Gly polymorphism in the development of cardiovascular diseases in HIV-infected patients.

Safety and immunogenicity of a modified pox vector-based HIV/AIDS vaccine candidate expressing Env, Gag, Pol and Nef proteins of HIV-1 subtype B (MVA-B) in healthy HIV-1-uninfected volunteers: A phase I clinical trial (RISVAC02).

Safety and immunogenicity of a modified vaccinia Ankara-based HIV-1 vaccine (MVA-B) in HIV-1-infected patients alone or in combination with a drug to reactivate latent HIV-1.

Safety and vaccine-induced HIV-1 immune responses in healthy volunteers following a late MVA-B boost 4 years after the last immunization.

Synergistic activity profile of carbosilane dendrimer G2-STE16 in combination with other dendrimers and antiretrovirals as topical anti-HIV-1 microbicide

Synthesis of new anionic carbosilane dendrimers via thiol-ene chemistry and their antiviral behaviour

Synthesis, structure and molecular modelling of anionic carbosilane dendrimers.

The HIV/AIDS vaccine candidate MVA-B administered as a single immunogen in humans triggers robust, polyfunctional, and selective effector memory T cell responses to HIV-1 antigens.

The Spanish HIV BioBank: a model of cooperative HIV research

Triple combination of carbosilane dendrimers, tenofovir and maraviroc as potential microbicide to prevent HIV-1 sexual transmission

Vector replication and expression of HIV-1 antigens by the HIV/AIDS vaccine candidate MVA-B is not affected by HIV-1 protease inhibitors

Virological phenotype switches under salvage therapy with lopinavir-ritonavir in heavily pretreated HIV-1 vertically infected children.

rs2228570 Polymorphism Is Related to Non-Progression to AIDS in Antiretroviral Therapy Naïve HIV-Infected Patients