List of works - Andreas Betz

Contribution of interactions with the core domain of hirudin to the stability of its complex with thrombin.

scientific article published on March 1994

Electrostatic steering and ionic tethering in the formation of thrombin-hirudin complexes: the role of the thrombin anion-binding exosite-I

scientific article published on 01 April 2001

Exosites Determine Macromolecular Substrate Recognition by Prothrombinase ⬇️

scientific article published on 01 October 1997

Interaction of the N-terminal region of hirudin with the active-site cleft of thrombin

scientific article published on May 19, 1992

Ionic interactions in the formation of the thrombin-hirudin complex ⬇️

scientific article published on May 1, 1991

Mapping of the thrombin des-ETW conformation by using site-directed mutants of hirudin. Evidence for the induction of nonlocal modifications by mutagenesis

scientific article published on 01 April 1994

Mechanistic studies on thrombin catalysis

scientific article published on 01 October 1991

Methotrexate and a spleen tyrosine kinase inhibitor cooperate to inhibit responses to peripheral blood B cells in rheumatoid arthritis

scientific article

Molecular basis for the inhibition of thrombin by hirudin

scientific article

PRT062607 Achieves Complete Inhibition of the Spleen Tyrosine Kinase at Tolerated Exposures Following Oral Dosing in Healthy Volunteers

scientific article published on 13 July 2016

Role of interactions involving C-terminal nonpolar residues of hirudin in the formation of the thrombin-hirudin complex

scientific article published on 01 October 1991

Selective inhibition of the prothrombinase complex: factor Va alters macromolecular recognition of a tick anticoagulant peptide mutant by factor Xa

scientific article published on 01 January 1997

Specific Inhibition of Spleen Tyrosine Kinase Suppresses Leukocyte Immune Function and Inflammation in Animal Models of Rheumatoid Arthritis ⬇️

scientific article published on October 31, 2011

The novel kinase inhibitor PRT062070 (Cerdulatinib) demonstrates efficacy in models of autoimmunity and B-cell cancer

scientific article published on 24 September 2014

The selective SYK inhibitor P505-15 (PRT062607) inhibits B cell signaling and function in vitro and in vivo and augments the activity of fludarabine in chronic lymphocytic leukemia

scientific article published on 7 December 2012

Transient hydrogen bonds identified on the surface of the NMR solution structure of Hirudin

scientific article published on 01 August 1994

pH Dependence of the interaction of hirudin with thrombin ⬇️

scientific article published on 01 February 1992

List of works by Andreas Betz