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List of works by Jacques Turgeon

A comparison of six major platelet function tests to determine the prevalence of aspirin resistance in patients with stable coronary artery disease

scientific article (publication date: July 2007)

ACE2 as a Therapeutic Target for COVID-19; its Role in Infectious Processes and Regulation by Modulators of the RAAS System

scientific article published on 03 July 2020

Adverse drug event risk assessment by the virtual addition of COVID-19 repurposed drugs to Medicare and commercially insured patients' drug regimens: A drug safety simulation study

scientific article published on 25 August 2021

An evaluation of pharmacists' expectations towards pharmacogenomics

scientific article

Assessing drug distribution in tissues expressing P-glycoprotein through physiologically based pharmacokinetic modeling: model structure and parameters determination

scientific article published on 15 January 2009

Assessing the Mechanism of Fluoxetine-Mediated CYP2D6 Inhibition ⬇️

journal article from 'Pharmaceutics' published in 2021

Assessment of competitive and mechanism-based inhibition by clarithromycin: use of domperidone as a CYP3A probe-drug substrate and various enzymatic sources including a new cell-based assay with freshly isolated human hepatocytes

scientific article published on April 2010

Association of a Novel Medication Risk Score with Adverse Drug Events and Other Pertinent Outcomes Among Participants of the Programs of All-Inclusive Care for the Elderly

scientific article published on 20 May 2020

Chronic Inflammatory Status Observed in Patients with Type 2 Diabetes Induces Modulation of Cytochrome P450 Expression and Activity ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2021

Clinical Practice Recommendations on Genetic Testing of CYP2C9 and VKORC1 Variants in Warfarin Therapy

scientific article

Clinical practice guideline: CYP2D6 genotyping for safe and efficacious codeine therapy

scientific article

Contribution of CYP2D6 Functional Activity to Oxycodone Efficacy in Pain Management: Genetic Polymorphisms, Phenoconversion, and Tissue-Selective Metabolism ⬇️

journal article from 'Pharmaceutics' published in 2021

Detection and prevention of drug-drug interactions in the hospitalized elderly: utility of new cytochrome p450-based software

scientific article published on 22 October 2011

Development and validation of probe drug cocktails for the characterization of CYP450-mediated metabolism by human heart microsomes

scientific article published on 16 February 2018

Disease-Induced Modulation of Drug Transporters at the Blood–Brain Barrier Level ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2021

Domperidone and sudden cardiac death: How much longer should we wait?

scientific article published in March 2013

Drug-induced long QT syndrome and torsade de pointes.

scientific article

Drug-induced long QT syndrome in women: review of current evidence and remaining gaps

scientific article published on June 2008

Effect of a single dose of ritonavir on the pharmacokinetic behavior of elvucitabine, a nucleoside reverse transcriptase inhibitor, administered in healthy volunteers

scientific article

Effectiveness of an Advanced Clinical Decision Support System on Clinical Decision-Making Skills in a Call Center Medication Therapy Management Pharmacy Setting: A Pilot Study

scientific article published on 25 November 2020

Effects of ciprofloxacin on the stereoselective disposition of mexiletine in man.

scientific article published in October 2004

Effects of β-blockers and tricyclic antidepressants on the activity of human organic anion transporting polypeptide 1A2 (OATP1A2).

scientific article

Emerging Non-statin Treatment Options for Lowering Low-Density Lipoprotein Cholesterol ⬇️

journal article from 'Frontiers in Cardiovascular Medicine' published in 2021

Enantioselective quantification of carvedilol in human plasma by HPLC in heavily medicated heart failure patients

scientific article published on 10 February 2010

Evaluating the impact of type 2 diabetes mellitus on CYP450 metabolic activities: protocol for a case-control pharmacokinetic study

scientific article published on 8 February 2018

Factors predisposing to coma and delirium: fentanyl and midazolam exposure; CYP3A5, ABCB1, and ABCG2 genetic polymorphisms; and inflammatory factors.

scientific article published in April 2013

Gender-related differences in drug-induced prolongation of cardiac repolarization in prepubertal guinea pigs

scientific article published in March 2009

Genetic determinants of response to aspirin: appraisal of 4 candidate genes

scientific article published on 22 March 2011

Highly sensitive LC-MS/MS methods for the determination of seven human CYP450 activities using small oral doses of probe-drugs in human

scientific article published on 6 December 2016

Impact of glucose concentration on cardiac ventricular repolarization under I Kr/I Ks blocking agents

scientific article

Implementation of a Standardized Medication Therapy Management Plus Approach within Primary Care

scientific article published in November 2017

Implementation of a pharmacist-led pharmacogenomics service for the Program of All-Inclusive Care for the Elderly (PHARM-GENOME-PACE).

scientific article published on 27 March 2018

Lengthening of cardiac repolarization in isolated guinea pigs hearts by sequential or concomitant administration of two IKr blockers

scientific article published on 23 December 2010

Mechanisms of CYP450 Inhibition: Understanding Drug-Drug Interactions Due to Mechanism-Based Inhibition in Clinical Practice

scientific article published on 04 September 2020

Medication Risk Mitigation: Coordinating and Collaborating with Health Care Systems, Universities, and Researchers to Facilitate the Design and Execution of Practice-Based Research

scientific article published on March 2017

Metabolic Activity and mRNA Levels of Human Cardiac CYP450s Involved in Drug Metabolism ⬇️

scientific article published on December 14, 2010

Multiple-dose pharmacokinetic behavior of elvucitabine, a nucleoside reverse transcriptase inhibitor, administered over 21 days with lopinavir-ritonavir in human immunodeficiency virus type 1-infected subjects

scientific article published on 17 November 2008

Olanzapine prolongs cardiac repolarization by blocking the rapid component of the delayed rectifier potassium current

scientific article published on 8 November 2006

Opioids, Polypharmacy, and Drug Interactions: A Technological Paradigm Shift Is Needed to Ameliorate the Ongoing Opioid Epidemic

scientific article published on 25 August 2020

Platelet count, not oxidative stress, may contribute to inadequate platelet inhibition by aspirin

scientific article published on 11 February 2009

Precision medication: An illustrative case series guiding the clinical application of multi-drug interactions and pharmacogenomics

scientific article published on 23 December 2019

QRS widening and QT prolongation under bupropion: a unique cardiac electrophysiological profile

scientific article published on 30 May 2011

Quantifying Anticholinergic Burden and Sedative Load in Older Adults with Polypharmacy: A Systematic Review of Risk Scales and Models ⬇️

publication published on 09 November 2021

Risk assessment of drug-induced Long QT Syndrome for some COVID-19 repurposed drugs

scientific article published on 05 September 2020

Risk of Adverse Drug Events Following the Virtual Addition of COVID-19 Repurposed Drugs to Drug Regimens of Frail Older Adults with Polypharmacy

scientific article published on 10 August 2020

Risk of drug-induced Long QT Syndrome associated with the use of repurposed COVID-19 drugs: a systematic review

scientific article published on 25 April 2020

Risperidone prolongs cardiac repolarization by blocking the rapid component of the delayed rectifier potassium current

scientific article published in June 2003

Role of CYP2D6 in the stereoselective disposition of venlafaxine in humans

scientific article

Rosuvastatin Blocks hERG Current and Prolongs Cardiac Repolarization ⬇️

scientific article published on November 11, 2011

Study of Statin- and Loratadine-Induced Muscle Pain Mechanisms Using Human Skeletal Muscle Cells

scientific article published on 10 October 2017

Ten renin-angiotensin system-related gene polymorphisms in maximally treated Canadian Caucasian patients with heart failure

scientific article published on 12 February 2008

The ATP-binding cassette transporters and their implication in drug disposition: a special look at the heart

scientific article

The Dangers of Polypharmacy in Elderly Patients

scientific article published in October 2017

The dual role of pharmacogenetics in HIV treatment: mutations and polymorphisms regulating antiretroviral drug resistance and disposition.

scientific article published on July 2012

The influence of CYP2D6 phenotype on the clinical response of nebivolol in patients with essential hypertension

scientific article

The pharmacokinetics of ezetimibe

scientific article published on January 1, 2003

Tissue Specific Modulation of cyp2c and cyp3a mRNA Levels and Activities by Diet-Induced Obesity in Mice: The Impact of Type 2 Diabetes on Drug Metabolizing Enzymes in Liver and Extra-Hepatic Tissues.

scientific article published on 26 September 2017

Understanding clopidogrel efficacy in the presence of cytochrome P450 polymorphism

scientific article published on June 2006

Week-long high-maintenance dose clopidogrel regimen achieves better platelet aggregation inhibition than a standard loading dose before percutaneous coronary intervention: results of a double-blind, randomized clinical trial

scientific article published in August 2009

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