Search filters

List of works by Susruta Majumdar

7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects

scientific article published on 29 May 2019

7-Hydroxymitragynine is an Active Metabolite of Mitragynine and a Key Mediator of its Analgesic Effects

article published in 2019

Broad-spectrum analgesic efficacy of IBNtxA is mediated by exon 11-associated splice variants of the mu-opioid receptor gene

scientific article

Fentanyl-related designer drugs W-18 and W-15 lack appreciable opioid activity in vitro and in vivo

scientific article

G protein-biased kratom-alkaloids and synthetic carfentanil-amide opioids as potential treatments for alcohol use disorder

scientific article published on 24 January 2020

Generation of novel radiolabeled opiates through site-selective iodination

scientific article

Genetic dissociation of morphine analgesia from hyperalgesia in mice

scientific article published on 25 March 2017

Imaging Sigma-1 Receptor (S1R) Expression Using Iodine-124-Labeled 1-(4-Iodophenyl)-3-(2-adamantyl)guanidine ([124I]IPAG)

scientific article published on 01 April 2020

Isocyanide-Based Multicomponent Reactions for the Synthesis of Heterocycles

scientific article

MP1104, a mixed kappa-delta opioid receptor agonist has anti-cocaine properties with reduced side-effects in rats

scientific article published on 13 February 2019

Mediation of buprenorphine analgesia by a combination of traditional and truncated mu opioid receptor splice variants

scientific article published on 25 May 2016

Mediation of opioid analgesia by a truncated 6-transmembrane GPCR.

scientific article

Mild, Pd-catalyzed stannylation of radioiodination targets

scientific article published on 2 March 2015

Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β-Arrestin-2.

scientific article

Natural products for the treatment of pain: chemistry and pharmacology of salvinorin A, mitragynine and collybolide

scientific article published on 15 September 2020

Novel 6β-acylaminomorphinans with analgesic activity

scientific article published on 22 September 2013

Oxidative Metabolism as a Modulator of Kratom’s Biological Actions

Pharmacologic characterization in the rat of a potent analgesic lacking respiratory depression, IBNtxA.

scientific article

Pharmacological Characterization of Levorphanol, a G-Protein Biased Opioid Analgesic.

scientific article published on 11 April 2018

Pharmacological characterization of novel synthetic opioids (NSO) found in the recreational drug marketplace.

scientific article published on 12 August 2017

Predicted Mode of Binding to and Allosteric Modulation of the μ-Opioid Receptor by Kratom's Alkaloids with Reported Antinociception <i>In Vivo</i>

scientific article published on 04 December 2020

Radioligand Binding Assay for an Exon 11-Associated Mu Opioid Receptor Target

scientific article published in January 2015

Sandmeyer reaction repurposed for the site-selective, non-oxidizing radioiodination of fully-deprotected peptides: studies on the endogenous opioid peptide α-neoendorphin.

scientific article published on 06 June 2013

Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor.

scientific article published on 3 January 2018

Synthesis and Characterization of Azido Aryl Analogs of IBNtxA for Radio-Photoaffinity Labeling Opioid Receptors in Cell Lines and in Mouse Brain

scientific article published on 18 May 2020

Synthesis and Evaluation of Aryl-Naloxamide Opiate Analgesics Targeting Truncated Exon 11-Associated μ Opioid Receptor (MOR-1) Splice Variants ⬇️

scientific article published on July 16, 2012

Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template

scientific article published on 10 November 2020

Synthesis and characterization of a dual kappa-delta opioid receptor agonist analgesic blocking cocaine reward behavior

scientific article

Synthesis and pharmacological evaluation of novel selective MOR agonist 6β-pyridinyl amidomorphines exhibiting long-lasting antinociception

scientific article published on 18 October 2016

Synthesis and pharmacology of halogenated δ-opioid-selective [d-Ala(2)]deltorphin II peptide analogues

scientific article published on 14 April 2015

Synthesis of Carfentanil Amide Opioids Using the Ugi Multicomponent Reaction.

scientific article published on 6 July 2015

Synthesis of spiro-2,6-dioxopiperazine and spiro-2,6-dioxopyrazine scaffolds using amino acids in a three-component reaction to generate potential Sigma-1 (σ1) receptor selective ligands

scientific article published on 22 December 2018

Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators

scientific article

Tetrapeptide Endomorphin Analogs Require Both Full Length and Truncated Splice Variants of the Mu Opioid Receptor Gene Oprm1 for Analgesia

scientific article

The mixed kappa and delta opioid receptor agonist, MP1104, attenuates chemotherapy-induced neuropathic pain

scientific article published on 28 December 2020

Three-component coupling approach for the synthesis of diverse heterocycles utilizing reactive nitrilium trapping.

scientific article published on 28 February 2014

Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects

scientific article

Truncated mu opioid GPCR variant involvement in opioid-dependent and opioid-independent pain modulatory systems within the CNS.

scientific article published on 14 March 2016

Truncated μ-Opioid Receptors With 6 Transmembrane Domains Are Essential for Opioid Analgesia

scientific article published on 4 October 2017

Paulina is supported by:

About Paulina

Help