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List of works by Catherine C Y Chang

A novel mouse model of Niemann-Pick type C disease carrying a D1005G-Npc1 mutation comparable to commonly observed human mutations.

scientific article

A stable upstream stem-loop structure enhances selection of the first 5'-ORF-AUG as a main start codon for translation initiation of human ACAT1 mRNA

scientific article

ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD.

scientific article

ACAT1/SOAT1 as a therapeutic target for Alzheimer's disease

scientific article

Acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) is induced in monocyte-derived macrophages: in vivo and in vitro studies

scientific article

Cholesterol is superior to 7-ketocholesterol or 7 alpha-hydroxycholesterol as an allosteric activator for acyl-coenzyme A:cholesterol acyltransferase 1

scientific article (publication date: 28 March 2003)

Cholesterol loading in macrophages stimulates formation of ER-derived vesicles with elevated ACAT1 activity

scientific article

Enhancement of human ACAT1 gene expression to promote the macrophage-derived foam cell formation by dexamethasone

scientific article

Functionality of the seventh and eighth transmembrane domains of acyl-coenzyme A:cholesterol acyltransferase 1

scientific article (publication date: 4 September 2007)

Human acyl-coenzyme A:cholesterol acyltransferase 1 (acat1) sequences located in two different chromosomes (7 and 1) are required to produce a novel ACAT1 isoenzyme with additional sequence at the N terminus

scientific article

Human acyl-coenzyme A:cholesterol acyltransferase expressed in chinese hamster ovary cells: membrane topology and active site location

scientific article published in June 2003

Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearance

scientific article

Niemann-Pick type C disease and intracellular cholesterol trafficking

scientific article

RNA secondary structures located in the interchromosomal region of human ACAT1 chimeric mRNA are required to produce the 56-kDa isoform

scientific article

Structural insights into the inhibition mechanism of human sterol O-acyltransferase 1 by a competitive inhibitor

scientific article published on 18 May 2020

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