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List of works by James Brett Case

A Potently Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection

scientific article published on 26 June 2020

A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies

scientific article published on 10 June 2020

A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2

scientific article published on 19 August 2020

A single intranasal or intramuscular immunization with chimpanzee adenovirus vectored SARS-CoV-2 vaccine protects against pneumonia in hamsters

scientific article published on 03 December 2020

Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses.

scientific article

Bruton's Tyrosine Kinase Synergizes with Notch2 To Govern Marginal Zone B Cells in Nonobese Diabetic Mice

scientific article

Bruton's tyrosine kinase promotes persistence of mature anti-insulin B cells.

scientific article

Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion

scholarly article

Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion

scientific article

Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease.

scientific article

Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody

scientific article published on 18 May 2020

De novo design of picomolar SARS-CoV-2 miniprotein inhibitors

scientific article published on 09 September 2020

Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail

scientific article published on 21 September 2021

Inhibition of PIKfyve kinase prevents infection by EBOV and SARS-CoV-2

scientific article published on 22 April 2020

JIB-04 Has Broad-Spectrum Antiviral Activity and Inhibits SARS-CoV-2 Replication and Coronavirus Pathogenesis

scientific article published on 18 January 2022

LDLRAD3 is a receptor for Venezuelan equine encephalitis virus

scientific article published on 18 November 2020

Mouse hepatitis virus nsp14 exoribonuclease activity is required for resistance to innate immunity

scientific article published on 30 August 2017

Murine hepatitis virus nsp14 exoribonuclease activity is required for resistance to innate immunity

scientific article published on 18 October 2017

Mutagenesis of S-Adenosyl-l-Methionine-Binding Residues in Coronavirus nsp14 N7-Methyltransferase Demonstrates Differing Requirements for Genome Translation and Resistance to Innate Immunity.

scientific article published on June 2016

Mutations in coronavirus nonstructural protein 10 decrease virus replication fidelity

scientific article published on 8 April 2015

Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2

scientific article published on 27 May 2020

Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2

scientific article published on 03 July 2020

Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2

scientific article published on 19 May 2020

Potently neutralizing and protective human antibodies against SARS-CoV-2

scientific article published on 15 July 2020

Potently neutralizing human antibodies that block SARS-CoV-2 receptor binding and protect animals

scientific article published on 22 May 2020

Proofreading-Deficient Coronaviruses Adapt for Increased Fitness over Long-Term Passage without Reversion of Exoribonuclease-Inactivating Mutations.

scientific article published on 7 November 2017

Proofreading-deficient coronaviruses adapt over long-term passage for increased fidelity and fitness without reversion of exoribonuclease-inactivating mutations

scientific article published on 12 August 2017

Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein

scientific article published on 14 May 2020

Rapid isolation and profiling of a diverse panel of human monoclonal antibodies targeting the SARS-CoV-2 spike protein

scientific article published on 10 July 2020

Replication-Competent Vesicular Stomatitis Virus Vaccine Vector Protects against SARS-CoV-2-Mediated Pathogenesis in Mice

scientific article published on 30 July 2020

Replication-competent vesicular stomatitis virus vaccine vector protects against SARS-CoV-2-mediated pathogenesis

scientific article published on 10 July 2020

Structural and functional analysis of a potent sarbecovirus neutralizing antibody

scientific article published on 09 April 2020

The SARS-CoV-2 B.1.1.529 Omicron virus causes attenuated infection and disease in mice and hamsters

Tolerant Anti-Insulin B Cells Are Effective APCs ⬇️

scientific article published on February 8, 2013

Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms

scientific article

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