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List of works by Masatoshi Okamatsu

A Low Pathogenic H5N2 Influenza Virus Isolated in Taiwan Acquired High Pathogenicity by Consecutive Passages in Chickens ⬇️

scientific article published on February 3, 2011

A Single Amino Acid in the M1 Protein Responsible for the Different Pathogenic Potentials of H5N1 Highly Pathogenic Avian Influenza Virus Strains.

scientific article published on 14 September 2015

A chicken influenza virus recognizes fucosylated α2,3 sialoglycan receptors on the epithelial cells lining upper respiratory tracts of chickens.

scientific article published on 4 April 2014

A cloned classical swine fever virus derived from the vaccine strain GPE- causes cytopathic effect in CPK-NS cells via type-I interferon-dependent necroptosis

scientific article published on 09 November 2019

A systematic study towards evolutionary and epidemiological dynamics of currently predominant H5 highly pathogenic avian influenza viruses in Vietnam

scientific article published on 22 May 2019

A vaccine prepared from a non-pathogenic H5N1 influenza virus strain from the influenza virus library conferred protective immunity to chickens against the challenge with antigenically drifted highly pathogenic avian influenza virus

scientific article published on February 1, 2011

Amino acid residues at positions 222 and 227 of the hemagglutinin together with the neuraminidase determine binding of H5 avian influenza viruses to sialyl Lewis X.

scientific article

An H5N1 highly pathogenic avian influenza virus that invaded Japan through waterfowl migration.

scientific article

An H9N2 Influenza Virus Vaccine Prepared from a Non-Pathogenic Isolate from a Migratory Duck Confers Protective Immunity in Mice against Challenge with an H9N2 Virus Isolated from a Girl in Hong Kong ⬇️

scientific article published on November 25, 2011

Analysis of a pair of END+ and END- viruses derived from the same bovine viral diarrhea virus stock reveals the amino acid determinants in Npro responsible for inhibition of type I interferon production

scientific article published on 28 December 2014

Antigenic and genetic analysis of H3N8 influenza viruses isolated from horses in Japan and Mongolia, and imported from Canada and Belgium during 2007-2010 ⬇️

scientific article published on April 20, 2011

Antigenic diversity of H5 highly pathogenic avian influenza viruses of clade 2.3.4.4 isolated in Asia.

scientific article published on 30 March 2017

Antigenic structure of the hemagglutinin of H9N2 influenza viruses

scientific article published on 07 November 2008

Antigenic, genetic, and pathogenic characterization of H5N1 highly pathogenic avian influenza viruses isolated from dead whooper swans (Cygnus cygnus) found in northern Japan in 2008 ⬇️

scientific article published on September 17, 2010

Characterization of H5N1 highly pathogenic avian influenza virus strains isolated from migratory waterfowl in Mongolia on the way back from the southern Asia to their northern territory

scientific article published on 31 July 2010

Characterization of H5N6 highly pathogenic avian influenza viruses isolated from wild and captive birds in the winter season of 2016-2017 in northern Japan

scientific article published on 16 August 2017

Characterization of H7N9 influenza A viruses isolated from humans.

scientific article

Characterization of Highly Pathogenic Avian Influenza Virus A(H5N6), Japan, November 2016

scientific article published on April 2017

Characterization of a non-pathogenic H5N1 influenza virus isolated from a migratory duck flying from Siberia in Hokkaido, Japan, in October 2009.

scientific article published on 11 February 2011

Characterization of avian influenza viruses isolated from domestic ducks in Vietnam in 2009 and 2010 ⬇️

scientific article published on November 9, 2011

Comparison of pathogenicities of H7 avian influenza viruses via intranasal and conjunctival inoculation in cynomolgus macaques.

scientific article published on 17 March 2016

Detection of highly pathogenic avian influenza virus infection in vaccinated chicken flocks by monitoring antibodies against non-structural protein 1 (NS1) ⬇️

scientific article published on July 7, 2010

E190V substitution of H6 hemagglutinin is one of key factors for binding to sulfated sialylated glycan receptor and infection to chickens

scientific article published on 14 January 2020

Efficacy of a cap-dependent endonuclease inhibitor and neuraminidase inhibitors against H7N9 highly pathogenic avian influenza virus causing severe viral pneumonia in cynomolgus macaques

scientific article published on 30 November 2020

Efficacy of neuraminidase inhibitors against H5N6 highly pathogenic avian influenza virus in a non-human primate model

scientific article published on 13 April 2020

Emergence of H7N9 Influenza A Virus Resistant to Neuraminidase Inhibitors in Nonhuman Primates.

scientific article published on 8 June 2015

Evaluation of a rapid isothermal nucleic acid amplification kit, Alere™ i Influenza A&B, for the detection of avian influenza viruses

scientific article published on 08 January 2019

Evaluation of the reverse transcription loop-mediated isothermal amplification (RT-LAMP) as a screening method for the detection of influenza viruses in the fecal materials of water birds

scientific article published on 28 January 2011

Excessive cytokine response to rapid proliferation of highly pathogenic avian influenza viruses leads to fatal systemic capillary leakage in chickens

scientific article

Experimental infection of highly and low pathogenic avian influenza viruses to chickens, ducks, tree sparrows, jungle crows, and black rats for the evaluation of their roles in virus transmission.

scientific article published on 17 November 2015

Factors responsible for pathogenicity in chickens of a low-pathogenic H7N7 avian influenza virus isolated from a feral duck.

scientific article published on 19 June 2013

Fluorescence polarization-based assay using N-glycan-conjugated quantum dots for screening in hemagglutinin blockers for influenza A viruses

scientific article published on 16 November 2012

Fluorescent immunochromatography for rapid and sensitive typing of seasonal influenza viruses

scientific article

Genetic analysis of an H5N2 highly pathogenic avian influenza virus isolated from a chicken in a live bird market in Northern Vietnam in 2012.

scientific article

Genetic and antigenic characterization of H5 and H7 avian influenza viruses isolated from migratory waterfowl in Mongolia from 2017 to 2019

scientific article published on 19 May 2020

Genetic and antigenic characterization of H5 and H7 influenza viruses isolated from migratory water birds in Hokkaido, Japan and Mongolia from 2010 to 2014.

scientific article

Genetic and antigenic characterization of H5, H6 and H9 avian influenza viruses circulating in live bird markets with intervention in the center part of Vietnam

scientific article published on 25 July 2016

Genetic and antigenic characterization of bovine viral diarrhea viruses isolated from cattle in Hokkaido, Japan

scientific article published on 21 September 2015

Genetic and antigenic characterization of the first H7N7 low pathogenic avian influenza viruses isolated in Vietnam

scientific article published on 21 November 2019

Genetic characterization and susceptibility on poultry and mammal of H7N6 subtype avian influenza virus isolated in Japan in 2009 ⬇️

scientific article published on January 10, 2011

H13 influenza viruses in wild birds have undergone genetic and antigenic diversification in nature

H9N2 influenza virus acquires intravenous pathogenicity on the introduction of a pair of di-basic amino acid residues at the cleavage site of the hemagglutinin and consecutive passages in chickens ⬇️

scientific article published on February 10, 2011

Humoral immune response to influenza A(H1N1)pdm2009 in patients with natural infection and in vaccine recipients in the 2009 pandemic.

scientific article

Improvement of the H5N1 influenza virus vaccine strain to decrease the pathogenicity in chicken embryos ⬇️

scientific article published on January 4, 2011

In vitro characterization of baloxavir acid, a first-in-class cap-dependent endonuclease inhibitor of the influenza virus polymerase PA subunit

scientific article published on 11 October 2018

Infection of newly identified phleboviruses in ticks and wild animals in Hokkaido, Japan indicating tick-borne life cycles

scientific article published on 16 November 2018

Inhibition of avian-origin influenza A(H7N9) virus by the novel cap-dependent endonuclease inhibitor baloxavir marboxil

scientific article published on 05 March 2019

Intracellular membrane association of the N-terminal domain of classical swine fever virus NS4B determines viral genome replication and virulence

scientific article published on 26 May 2015

Intranasal administration of a live non-pathogenic avian H5N1 influenza virus from a virus library confers protective immunity against H5N1 highly pathogenic avian influenza virus infection in mice: comparison of formulations and administration rout

scientific article

Is the optimal pH for membrane fusion in host cells by avian influenza viruses related to host range and pathogenicity?

scientific article published on 26 May 2016

Long lasting immunity in chickens induced by a single shot of influenza vaccine prepared from inactivated non-pathogenic H5N1 virus particles against challenge with a highly pathogenic avian influenza virus

scientific article published on 9 July 2009

Low replicative fitness of neuraminidase inhibitor-resistant H7N9 avian influenza a virus with R292K substitution in neuraminidase in cynomolgus macaques compared with I222T substitution

scientific article published on 06 April 2020

Memory immune responses against pandemic (H1N1) 2009 influenza virus induced by a whole particle vaccine in cynomolgus monkeys carrying Mafa-A1*052:02

scientific article

Novel trivalent anti-influenza reagent

scientific article

PB2 protein of a highly pathogenic avian influenza virus strain A/chicken/Yamaguchi/7/2004 (H5N1) determines its replication potential in pigs

scientific article published on 03 December 2008

Pathogenicity of pandemic H1N1 influenza A virus in immunocompromised cynomolgus macaques

scientific article (publication date: 2013)

Polymerase complex with lysine at position 627 of the PB2 of influenza virus A/Hong Kong/483/97 (H5N1) efficiently transcribes and replicates virus genes in mouse cells

scientific article published on 23 September 2013

Potency of a vaccine prepared from A/swine/Hokkaido/2/1981 (H1N1) against A/Narita/1/2009 (H1N1) pandemic influenza virus strain

scientific article

Potency of an Inactivated Influenza Vaccine against a Challenge with A/Swine/Missouri/A01727926/2015 (H4N6) in Mice for Pandemic Preparedness

scientific article published on 16 December 2020

Potency of an inactivated influenza vaccine prepared from A/duck/Hong Kong/960/1980 (H6N2) against a challenge with A/duck/Vietnam/OIE-0033/2012 (H6N2) in mice.

scientific article

Potency of an inactivated influenza vaccine prepared from A/duck/Mongolia/119/2008 (H7N9) against the challenge with A/Anhui/1/2013 (H7N9).

scientific article

Potency of an inactivated influenza vaccine prepared from a non-pathogenic H5N1 virus against a challenge with antigenically drifted highly pathogenic avian influenza viruses in chickens

scientific article published on 8 February 2013

Potency of whole virus particle and split virion vaccines using dissolving microneedle against challenges of H1N1 and H5N1 influenza viruses in mice.

scientific article published on 18 April 2017

Protection against H5N1 highly pathogenic avian and pandemic (H1N1) 2009 influenza virus infection in cynomolgus monkeys by an inactivated H5N1 whole particle vaccine

scientific article

Protective efficacy of passive immunization with monoclonal antibodies in animal models of H5N1 highly pathogenic avian influenza virus infection

scientific article (publication date: June 2014)

Protective efficacy of stockpiled vaccine against H5N8 highly pathogenic avian influenza virus isolated from a chicken in Kumamoto prefecture, Japan, in 2014.

scientific article published on 20 August 2015

Proteins of duck influenza virus responsible for acquisition of pathogenicity in chickens

scientific article published on 19 February 2013

Purification of human and avian influenza viruses using cellulose sulfate ester (Cellufine Sulfate) in the process of vaccine production ⬇️

scientific article published on 01 July 2012

Rapid and broad detection of H5 hemagglutinin by an immunochromatographic kit using novel monoclonal antibody against highly pathogenic avian influenza virus belonging to the genetic clade 2.3.4.4.

scientific article published on 7 August 2017

Recent developments in the diagnosis of avian influenza.

scientific article

Reintroduction of H5N1 highly pathogenic avian influenza virus by migratory water birds, causing poultry outbreaks in the 2010–2011 winter season in Japan ⬇️

scientific article published on November 23, 2011

Repeated detection of H7N9 avian influenza viruses in raw poultry meat illegally brought to Japan by international flight passengers

Selection of H3 avian influenza viruses with SAα2,6Gal receptor specificity in pigs

scientific article

Selection of antigenic variants of an H5N1 highly pathogenic avian influenza virus in vaccinated chickens

scientific article

Selection of classical swine fever virus with enhanced pathogenicity reveals synergistic virulence determinants in E2 and NS4B

scientific article

Spatiotemporal and risk analysis of H5 highly pathogenic avian influenza in Vietnam, 2014-2017

scientific article published on 22 April 2019

The N-terminal domain of Npro of classical swine fever virus determines its stability and regulates type I IFN production.

scientific article

The PB2, PA, HA, NP, and NS genes of a highly pathogenic avian influenza virus A/whooper swan/Mongolia/3/2005 (H5N1) are responsible for pathogenicity in ducks ⬇️

scientific article published on February 2, 2013

The clinically used serine protease inhibitor nafamostat reduces influenza virus replication and cytokine production in human airway epithelial cells and viral replication in mice

scientific article published on 28 November 2020

The genetic and antigenic diversity of avian influenza viruses isolated from domestic ducks, muscovy ducks, and chickens in northern and southern Vietnam, 2010-2012.

scientific article published on 17 July 2013

The nucleoprotein is responsible for intracerebral pathogenicity of A/duck/Mongolia/47/2001 (H7N1) in chicks ⬇️

scientific article published on July 26, 2012

Therapeutic efficacy of peramivir against H5N1 highly pathogenic avian influenza viruses harboring the neuraminidase H275Y mutation

scientific article published on 21 December 2016

Vaccination against H9N2 avian influenza virus reduces bronchus-associated lymphoid tissue formation in cynomolgus macaques after intranasal virus challenge infection.

scientific article

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