List of works - Karel Bezouška

1(st) Central and Eastern European Proteomic Conference & 3(rd) Czech Proteomic Conference 29 - 31 October 2007, Prague, Czech Republic

scientific article published on 01 March 2008

A chemoenzymatic route to mannosamine derivatives bearing different N-acyl groups

scientific article published in January 2005

Carbohydrate and Non-Carbohydrate Ligands for the C-Type Lectin-Like Receptors of Natural Killer Cells. A Review

scientific article published in 2004

Carbohydrate synthesis and biosynthesis technologies for cracking of the glycan code: recent advances.

scientific article published on 28 March 2012

Carboxylated calixarenes bind strongly to CD69 and protect CD69(+) killer cells from suicidal cell death induced by tumor cell surface ligands

scientific article published on 11 January 2010

Chemical Cross-Linking and H/D Exchange for Fast Refinement of Protein Crystal Structure

scientific article published on 23 December 2011

Comblike dendrimers containing Tn antigen modulate natural killing and induce the production of Tn specific antibodies

scientific article published on 01 October 2006

Cooperation between subunits is essential for high-affinity binding of N-acetyl-D-hexosamines to dimeric soluble and dimeric cellular forms of human CD69

scientific article published on 01 May 2010

Crystallization and diffraction analysis of β-N-acetylhexosaminidase from Aspergillus oryzae.

scientific article

Crystallization and preliminary crystallographic characterization of the iron-regulated outer membrane lipoprotein FrpD from Neisseria meningitidis

scientific article published on 28 August 2010

Deoxynojirimycin and its hexosaminyl derivatives bind to natural killer cell receptors rNKR-P1A and hCD69.

scientific article published on 8 June 2010

Design, functional evaluation and biomedical applications of carbohydrate dendrimers (glycodendrimers).

scientific article

Dimerization of an immunoactivating peptide derived from mycobacterial hsp65 using N-hydroxysuccinimide based bifunctional reagents is critical for its antitumor properties.

scientific article

Effects of N-acetyl-glucosamine-coated glycodendrimers as biological modulators in the B16F10 melanoma model in vivo.

scientific article

Enzymatic characterization and molecular modeling of an evolutionarily interesting fungal β-N-acetylhexosaminidase.

scientific article

Enzymatic synthesis of dimeric glycomimetic ligands of NK cell activation receptors

scientific article published on 03 May 2011

Erratum to: Purification and characterization of a nitrilase from Aspergillus niger K10.

scientific article published in April 2013

Erratum to: Purification and characterization of heterologously expressed nitrilases from filamentous fungi

scholarly article published in Applied Microbiology and Biotechnology

Facile production of Aspergillus niger α-N-acetylgalactosaminidase in yeast.

scientific article published on 29 September 2011

Fluorescent labelled thiourea-bridged glycodendrons

scientific article

Fragmentation of human erythrocyte actin following exposure to hypoxia.

scientific article

Fungal nitrilases as biocatalysts: Recent developments.

scientific article published on 07 May 2009

Genome mining for the discovery of new nitrilases in filamentous fungi

scientific article published on 30 September 2010

Glycosylation protects proteins against free radicals generated from toxic xenobiotics

scientific article

Heterologous expression, purification and characterization of nitrilase from Aspergillus niger K10

scientific article

High-level expression of soluble form of mouse natural killer cell receptor NKR-P1C(B6) in Escherichia coli.

scientific article published in February 2011

Humoral response against Mycobacterium bovis Hsp65 derived fragments in children and young people with various disorders

scientific article published in January 2008

Identification of the N-glycosylation sites on glutamate carboxypeptidase II necessary for proteolytic activity

scientific article

Induction and characterization of an unusual α-d-galactosidase from Talaromyces flavus

scientific article published in January 2007

Large Propeptides of Fungal β-N-Acetylhexosaminidases Are Novel Enzyme Regulators That Must Be Intracellularly Processed to Control Activity, Dimerization, and Secretion into the Extracellular Environment†

scientific article published on 16 February 2007

Long-Read Genome Sequence of the Sugar Beet Rhizosphere Mycoparasite Pythium oligandrum

scientific article published on 06 February 2020

Mass spectrometric analysis of the glycosphingolipid-enriched microdomains of rat natural killer cells.

scientific article published on January 2005

Modified electrophoretic and digestion conditions allow a simplified mass spectrometric evaluation of disulfide bonds.

scientific article

Molecular architecture of mouse activating NKR-P1 receptors

scientific article

Molecular characterization of binding of calcium and carbohydrates by an early activation antigen of lymphocytes CD69

scientific journal article

Monitoring of in vitro deamidation of gliadin peptic fragment by mass spectrometry may reflect one of the molecular mechanisms taking place in celiac disease development

scientific article

Mouse Clr-g, a ligand for NK cell activation receptor NKR-P1F: crystal structure and biophysical properties

scientific article

N-acetyl-D-glucosamine substituted calix[4]arenes as stimulators of NK cell-mediated antitumor immune response

scientific article published on 06 May 2007

Preparation of soluble isotopically labeled NKp30, a human natural cytotoxicity receptor, for structural studies using NMR

scientific article published on 08 October 2012

Purification and characterization of a nitrilase from Aspergillus niger K10

scientific article published on 24 October 2006

Purification and characterization of heterologously expressed nitrilases from filamentous fungi.

scientific article published on 3 September 2011

Retraction notice to “Carboxylated calixarenes bind strongly to CD69 and protect CD69+ killer cells from suicidal cell death induced by tumor cell surface ligands” [Bioorg. Med. Chem. 18 (4) (2010) 1434–1440]

scientific article published on 01 June 2014

Retraction of Cooperation between Subunits Is Essential for High-Affinity Binding of N-Acetyl-d-hexosamines to Dimeric Soluble and Dimeric Cellular Forms of Human CD69

scientific article published on 15 April 2014

Retraction of “Synthesis of Multivalent Glycoconjugates Containing the Immunoactive LELTE Peptide: Effect of Glycosylation on Cellular Activation and Natural Killing by Human Peripheral Blood Mononuclear Cells”

scientific article published in 2014

Retraction: Heterologous expression, purification and characterization of nitrilase from Aspergillus niger K10

Retraction: Oligosaccharide ligands for NKR-P1 protein activate NK cells and cytotoxicity

scientific article published on 03 July 2013

Retraction: Synthetic N-acetyl-D-glucosamine based fully branched tetrasaccharide, a mimetic of the endogenous ligand for CD69, activates CD69⁺ killer lymphocytes upon dimerization via a hydrophilic flexible linker. Journal of Medicinal Chemistry 20

scientific article published on 5 June 2014

Soluble recombinant CD69 receptors optimized to have an exceptional physical and chemical stability display prolonged circulation and remain intact in the blood of mice

scientific article

Structural analysis of natural killer cell receptor protein 1 (NKR-P1) extracellular domains suggests a conserved long loop region involved in ligand specificity.

scientific article published on 14 September 2010

Structure of the H107R variant of the extracellular domain of mouse NKR-P1A at 2.3 Å resolution

scientific article

Structure of the dimeric N-glycosylated form of fungal beta-N-acetylhexosaminidase revealed by computer modeling, vibrational spectroscopy, and biochemical studies.

scientific article

Sugar-mediated lattice contacts in crystals of a plant glycoprotein

scientific article published on 26 September 2002

Synthesis and biological activity of glycosyl-1H-1,2,3-triazoles.

scientific article published on 15 May 2010

Synthesis of LacdiNAc-terminated glycoconjugates by mutant galactosyltransferase--a way to new glycodrugs and materials

scientific article published on 29 January 2009

Synthesis of Linear and Branched Regioisomeric Chitooligosaccharides as Potential Mimetics of Natural Oligosaccharide Ligands of Natural Killer Cells NKR-P1 and CD69 Lectin Receptors

scientific article published in 2004

Synthesis of multivalent glycoconjugates containing the immunoactive LELTE peptide: effect of glycosylation on cellular activation and natural killing by human peripheral blood mononuclear cells.

scientific article

Synthetic N-acetyl-D-glucosamine based fully branched tetrasaccharide, a mimetic of the endogenous ligand for CD69, activates CD69+ killer lymphocytes upon dimerization via a hydrophilic flexible linker.

scientific article

The Isoforms of Rat Natural Killer Cell Receptor NKR-P1 Display a Distinct Binding of Complex Saccharide Ligands - RETRACTED

scientific article published in 2004

The high-resolution structure of the extracellular domain of human CD69 using a novel polymer

scientific article

The α-galactosidase type A gene aglA from Aspergillus niger encodes a fully functional α-N-acetylgalactosaminidase.

scientific article

List of works by Karel Bezouška

1(st) Central and Eastern European Proteomic Conference & 3(rd) Czech Proteomic Conference 29 - 31 October 2007, Prague, Czech Republic

A chemoenzymatic route to mannosamine derivatives bearing different N-acyl groups

Carbohydrate and Non-Carbohydrate Ligands for the C-Type Lectin-Like Receptors of Natural Killer Cells. A Review

Carbohydrate synthesis and biosynthesis technologies for cracking of the glycan code: recent advances.

Carboxylated calixarenes bind strongly to CD69 and protect CD69(+) killer cells from suicidal cell death induced by tumor cell surface ligands

Chemical Cross-Linking and H/D Exchange for Fast Refinement of Protein Crystal Structure

Comblike dendrimers containing Tn antigen modulate natural killing and induce the production of Tn specific antibodies

Cooperation between subunits is essential for high-affinity binding of N-acetyl-D-hexosamines to dimeric soluble and dimeric cellular forms of human CD69

Crystallization and diffraction analysis of β-N-acetylhexosaminidase from Aspergillus oryzae.

Crystallization and preliminary crystallographic characterization of the iron-regulated outer membrane lipoprotein FrpD from Neisseria meningitidis

Deoxynojirimycin and its hexosaminyl derivatives bind to natural killer cell receptors rNKR-P1A and hCD69.

Design, functional evaluation and biomedical applications of carbohydrate dendrimers (glycodendrimers).

Dimerization of an immunoactivating peptide derived from mycobacterial hsp65 using N-hydroxysuccinimide based bifunctional reagents is critical for its antitumor properties.

Effects of N-acetyl-glucosamine-coated glycodendrimers as biological modulators in the B16F10 melanoma model in vivo.

Enzymatic characterization and molecular modeling of an evolutionarily interesting fungal β-N-acetylhexosaminidase.

Enzymatic synthesis of dimeric glycomimetic ligands of NK cell activation receptors

Erratum to: Purification and characterization of a nitrilase from Aspergillus niger K10.

Erratum to: Purification and characterization of heterologously expressed nitrilases from filamentous fungi

Facile production of Aspergillus niger α-N-acetylgalactosaminidase in yeast.

Fluorescent labelled thiourea-bridged glycodendrons

Fragmentation of human erythrocyte actin following exposure to hypoxia.

Fungal nitrilases as biocatalysts: Recent developments.

Genome mining for the discovery of new nitrilases in filamentous fungi

Glycosylation protects proteins against free radicals generated from toxic xenobiotics

Heterologous expression, purification and characterization of nitrilase from Aspergillus niger K10

High-level expression of soluble form of mouse natural killer cell receptor NKR-P1C(B6) in Escherichia coli.

Humoral response against Mycobacterium bovis Hsp65 derived fragments in children and young people with various disorders

Identification of the N-glycosylation sites on glutamate carboxypeptidase II necessary for proteolytic activity

Induction and characterization of an unusual α-d-galactosidase from Talaromyces flavus

Large Propeptides of Fungal β-N-Acetylhexosaminidases Are Novel Enzyme Regulators That Must Be Intracellularly Processed to Control Activity, Dimerization, and Secretion into the Extracellular Environment†

Long-Read Genome Sequence of the Sugar Beet Rhizosphere Mycoparasite Pythium oligandrum

Mass spectrometric analysis of the glycosphingolipid-enriched microdomains of rat natural killer cells.

Modified electrophoretic and digestion conditions allow a simplified mass spectrometric evaluation of disulfide bonds.

Molecular architecture of mouse activating NKR-P1 receptors

Molecular characterization of binding of calcium and carbohydrates by an early activation antigen of lymphocytes CD69

Monitoring of in vitro deamidation of gliadin peptic fragment by mass spectrometry may reflect one of the molecular mechanisms taking place in celiac disease development

Mouse Clr-g, a ligand for NK cell activation receptor NKR-P1F: crystal structure and biophysical properties

N-acetyl-D-glucosamine substituted calix[4]arenes as stimulators of NK cell-mediated antitumor immune response

Preparation of soluble isotopically labeled NKp30, a human natural cytotoxicity receptor, for structural studies using NMR

Purification and characterization of a nitrilase from Aspergillus niger K10

Purification and characterization of heterologously expressed nitrilases from filamentous fungi.

Retraction notice to “Carboxylated calixarenes bind strongly to CD69 and protect CD69+ killer cells from suicidal cell death induced by tumor cell surface ligands” [Bioorg. Med. Chem. 18 (4) (2010) 1434–1440]

Retraction of Cooperation between Subunits Is Essential for High-Affinity Binding of N-Acetyl-d-hexosamines to Dimeric Soluble and Dimeric Cellular Forms of Human CD69

Retraction of “Synthesis of Multivalent Glycoconjugates Containing the Immunoactive LELTE Peptide: Effect of Glycosylation on Cellular Activation and Natural Killing by Human Peripheral Blood Mononuclear Cells”

Retraction: Heterologous expression, purification and characterization of nitrilase from Aspergillus niger K10

Retraction: Oligosaccharide ligands for NKR-P1 protein activate NK cells and cytotoxicity

Retraction: Synthetic N-acetyl-D-glucosamine based fully branched tetrasaccharide, a mimetic of the endogenous ligand for CD69, activates CD69⁺ killer lymphocytes upon dimerization via a hydrophilic flexible linker. Journal of Medicinal Chemistry 20

Soluble recombinant CD69 receptors optimized to have an exceptional physical and chemical stability display prolonged circulation and remain intact in the blood of mice

Structural analysis of natural killer cell receptor protein 1 (NKR-P1) extracellular domains suggests a conserved long loop region involved in ligand specificity.

Structure of the H107R variant of the extracellular domain of mouse NKR-P1A at 2.3 Å resolution

Structure of the dimeric N-glycosylated form of fungal beta-N-acetylhexosaminidase revealed by computer modeling, vibrational spectroscopy, and biochemical studies.

Sugar-mediated lattice contacts in crystals of a plant glycoprotein

Synthesis and biological activity of glycosyl-1H-1,2,3-triazoles.

Synthesis of LacdiNAc-terminated glycoconjugates by mutant galactosyltransferase--a way to new glycodrugs and materials

Synthesis of Linear and Branched Regioisomeric Chitooligosaccharides as Potential Mimetics of Natural Oligosaccharide Ligands of Natural Killer Cells NKR-P1 and CD69 Lectin Receptors

Synthesis of multivalent glycoconjugates containing the immunoactive LELTE peptide: effect of glycosylation on cellular activation and natural killing by human peripheral blood mononuclear cells.

Synthetic N-acetyl-D-glucosamine based fully branched tetrasaccharide, a mimetic of the endogenous ligand for CD69, activates CD69+ killer lymphocytes upon dimerization via a hydrophilic flexible linker.

The Isoforms of Rat Natural Killer Cell Receptor NKR-P1 Display a Distinct Binding of Complex Saccharide Ligands - RETRACTED

The high-resolution structure of the extracellular domain of human CD69 using a novel polymer

The α-galactosidase type A gene aglA from Aspergillus niger encodes a fully functional α-N-acetylgalactosaminidase.