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List of works by Christoph Huber

A methodological framework to enhance the clinical success of cancer immunotherapy ⬇️

scientific article published on October 13, 2011

A neoepitope generated by an FLT3 internal tandem duplication (FLT3-ITD) is recognized by leukemia-reactive autologous CD8+ T cells

scientific article published on April 2007

A phase I dose-escalation study of IMAB362 (Zolbetuximab) in patients with advanced gastric and gastro-oesophageal junction cancer

scientific article published on 21 June 2018

A phase I vaccination study with tyrosinase in patients with stage II melanoma using recombinant modified vaccinia virus Ankara (MVA-hTyr).

scientific article published on 31 December 2004

A placenta-specific gene ectopically activated in many human cancers is essentially involved in malignant cell processes

scientific article

Actively personalized vaccination trial for newly diagnosed glioblastoma

scientific article published on 19 December 2018

Altered expression of nonclassical HLA class Ib antigens in human renal cell carcinoma and its association with impaired immune response

scientific article published on 01 November 2003

An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma

scientific article published on 29 July 2020

An immune escape screen reveals Cdc42 as regulator of cancer susceptibility to lymphocyte-mediated tumor suppression

scientific article published on 30 October 2007

An open-label, prospective phase I/II study evaluating the immunogenicity and safety of a ras peptide vaccine plus GM-CSF in patients with non-small cell lung cancer

scientific article published on 27 June 2007

Analysis of the structural integrity of the TAP2 gene in renal cell carcinoma

scientific article published on 01 October 2003

Aortic root dimensions among patients with severe aortic stenosis undergoing transcatheter aortic valve replacement

scientific article published in January 2013

Atrial fibrillation and aortic stenosis: impact on clinical outcomes among patients undergoing transcatheter aortic valve implantation

scientific article published on 5 February 2013

Awareness and understanding of cancer immunotherapy in Europe

scientific article

CD8+ cytotoxic T lymphocytes isolated from allogeneic healthy donors recognize HLA class Ia/Ib-associated renal carcinoma antigens with ubiquitous or restricted tissue expression

scientific article published in July 2004

Cancer classification using the Immunoscore: a worldwide task force

scientific article

Cerebrovascular accidents complicating transcatheter aortic valve implantation: frequency, timing and impact on outcomes

scientific article published in May 2012

Characterization of human lymphocyte antigen class I antigen-processing machinery defects in renal cell carcinoma lesions with special emphasis on transporter-associated with antigen-processing down-regulation ⬇️

scientific article published on May 1, 2003

Claudin-18 splice variant 2 is a pan-cancer target suitable for therapeutic antibody development

scientific article

Clinical outcome and predictors for adverse events after transcatheter aortic valve implantation with the use of different devices and access routes

scientific article published on 11 May 2011

Clinical outcome of high-risk patients with severe aortic stenosis and reduced left ventricular ejection fraction undergoing medical treatment or TAVI

scientific article (publication date: 2011)

Clinical outcomes and revascularization strategies in patients with low-flow, low-gradient severe aortic valve stenosis according to the assigned treatment modality

scientific article published on April 2015

Clinical outcomes of patients with estimated low or intermediate surgical risk undergoing transcatheter aortic valve implantation

scientific article published on 13 March 2013

Clinical outcomes of patients with severe aortic stenosis at increased surgical risk according to treatment modality

scientific article published on 01 November 2011

Cloning and functional analyses of the mouse tapasin promoter

scientific article published on 26 August 2003

Coexpression of the T-cell receptor constant alpha domain triggers tumor reactivity of single-chain TCR-transduced human T cells

scientific article published on 8 April 2010

Comparison of procedural and clinical outcomes with Evolut R versus Medtronic CoreValve: a Swiss TAVI registry analysis

scientific article published on 10 January 2017

Cooperation of Human Tumor-Reactive CD4+ and CD8+ T Cells after Redirection of Their Specificity by a High-Affinity p53A2.1-Specific TCR

scientific article published on 01 January 2005

Coronary artery disease severity and aortic stenosis: clinical outcomes according to SYNTAX score in patients undergoing transcatheter aortic valve implantation.

scientific article published on 28 March 2014

CrELISA: a fast and robust enzyme-linked immunosorbent assay bypassing the need for purification of recombinant protein.

scientific article

Current results on the use of imatinib mesylate in patients with relapsed philadelphia chromosome positive leukemia after allogeneic or syngeneic hematopoietic stem cell transplantation ⬇️

scientific article published on September 1, 2003

Defining the critical hurdles in cancer immunotherapy

scientific article published on 14 December 2011

Detection of a germline mutation and somatic homozygous loss of the von Hippel-Lindau tumor-suppressor gene in a family with a de novo mutation

article

Dissection and molecular analysis of alloreactive CD8+ T cell responses in allogeneic haematopoietic stem cell transplantation

scientific article published on 15 November 2007

Editorial Comment: Re-operation: a thing of the past? Transcatheter aortic valve-in-valve implantation for failed surgical bioprosthesis ⬇️

scientific article published on March 16, 2012

Effect of Pulmonary Hypertension Hemodynamic Presentation on Clinical Outcomes in Patients With Severe Symptomatic Aortic Valve Stenosis Undergoing Transcatheter Aortic Valve Implantation: Insights From the New Proposed Pulmonary Hypertension Classi

scientific article published on July 2015

Effect of resting heart rate on two-year clinical outcomes of high-risk patients with severe symptomatic aortic stenosis undergoing transcatheter aortic valve implantation

scientific article published on 01 July 2016

Efficacy and safety of imatinib in adult patients with c-kit-positive acute myeloid leukemia

scientific article

Erratum: Mutant MHC class II epitopes drive therapeutic immune responses to cancer

scientific article published in Nature

Evaluation of genetic melanoma vaccines in cdk4-mutant mice provides evidence for immunological tolerance against authochthonous melanomas in the skin.

scientific article published in January 2006

Expanding Indications of Transcatheter Heart Valve Interventions

scientific article

Exploiting the mutanome for tumor vaccination.

scientific article published on 11 January 2012

Expression of multiple epigenetically regulated cancer/germline genes in nonsmall cell lung cancer

scientific article

FLT3 ligand enhances the cancer therapeutic potency of naked RNA vaccines.

scientific article

Frequent nonrandom activation of germ-line genes in human cancer

scientific article published in September 2004

Functional role of human leukocyte antigen-G up-regulation in renal cell carcinoma

scientific article published on 01 July 2003

Graft preservation solutions in cardiovascular surgery.

scientific article published on 10 April 2016

High frequency of a non-functional TAP1/LMP2 promoter polymorphism in human tumors

scientific article published on 01 February 2002

Identification of T cell epitopes by the use of rapidly generated mRNA fragments

scientific article published on 31 March 2005

Impact of coronary artery disease and percutaneous coronary intervention on outcomes in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation

scientific article published on 01 September 2011

Impact of mitral regurgitation on clinical outcomes of patients with low-ejection fraction, low-gradient severe aortic stenosis undergoing transcatheter aortic valve implantation

scientific article published in February 2015

Impact of new technologies and experience on procedural aspects of surgical aortic valve replacement - a process analysis

scientific article published on 11 July 2017

Impact of permanent pacemaker implantation on clinical outcome among patients undergoing transcatheter aortic valve implantation

scientific article published on 20 June 2012

Impaired transporter associated with antigen processing (TAP) function attributable to a single amino acid alteration in the peptide TAP subunit TAP1.

scientific article published on January 2003

Increased Antigen Presentation Efficiency by Coupling Antigens to MHC Class I Trafficking Signals

scientific article published on 01 January 2008

Increased tumorigenicity, but unchanged immunogenicity, of transporter for antigen presentation 1-deficient tumors

scientific article

Infective Endocarditis After Transcatheter Aortic Valve Replacement

scientific article published on 01 June 2020

Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity.

scientific article published on 2 November 2010

Is surgery in acute aortic dissection type A still contraindicated in the presence of preoperative neurological symptoms?

scientific article published on 20 January 2015

Long-term follow-up after implantation of the Shelhigh® No-React® complete biological aortic valved conduit

scientific article published on 30 December 2015

Long-term outcome of elderly patients with severe aortic stenosis as a function of treatment modality

scientific article published on 27 August 2014

MS4A12 is a colon-selective store-operated calcium channel promoting malignant cell processes

scientific article

Minimally invasive extracorporeal circulation: excellent outcome and life expectancy after coronary artery bypass grafting surgery

scientific article published on 11 July 2017

Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells.

scientific article

Molecular design of the Calphabeta interface favors specific pairing of introduced TCRalphabeta in human T cells

scientific article published on 01 January 2008

Multiple splice variants of lactate dehydrogenase C selectively expressed in human cancer.

scientific article published in November 2002

Mutant MHC class II epitopes drive therapeutic immune responses to cancer

scientific article published on 22 April 2015

Partial tyrosinase-specific self tolerance by HLA-A*0201-restricted cytotoxic T lymphocytes in mice and man

scientific article published on 01 February 2004

Percutaneous Transcatheter Closure for Aortic Puncture and Paravalvular Leak Closure With the New Amplatzer III Device

scientific article published on 24 June 2015

Percutaneous management of vascular complications in patients undergoing transcatheter aortic valve implantation

scientific article published in May 2012

Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer

scientific article published on 5 July 2017

Pitfalls in TAMVI: experience with the repositionable Lotus® Valve System

scientific article

Predicting Mortality After Transcatheter Aortic Valve Replacement: External Validation of the Transcatheter Valve Therapy Registry Model.

scientific article

Predictors of clinical outcomes in patients with severe aortic stenosis undergoing TAVI: a multistate analysis

scientific article published on 20 November 2012

Predictors of functional decline in elderly patients undergoing transcatheter aortic valve implantation (TAVI).

scientific article published on 24 September 2012

Procedural Results and Clinical Outcomes of Transcatheter Aortic Valve Implantation in Switzerland: An Observational Cohort Study of Sapien 3 Versus Sapien XT Transcatheter Heart Valves

scientific article published on October 2015

Proteasome-inhibited dendritic cells demonstrate improved presentation of exogenous synthetic and natural HLA-class I peptide epitopes

scientific article published on 28 November 2005

Publisher Correction: Actively personalized vaccination trial for newly diagnosed glioblastoma

scientific article published on 01 February 2019

Quality of life in high-risk patients: comparison of transcatheter aortic valve implantation with surgical aortic valve replacement

scientific article published on 24 April 2012

Rapid and sensitive identification of major histocompatibility complex class I-associated tumor peptides by Nano-LC MALDI MS/MS.

scientific article published on 19 August 2005

Rapid identification and sorting of viable virus-reactive CD4(+) and CD8(+) T cells based on antigen-triggered CD137 expression

scientific article published on 27 August 2008

Rapid identification of an HLA-B*1501-restricted vaccinia peptide antigen

scientific article published on 25 April 2007

Recovery of varicella-zoster virus-specific T cell immunity after T cell-depleted allogeneic transplantation requires symptomatic virus reactivation

scientific article published in December 2008

Redirection of T cells by delivering a transgenic mouse-derived MDM2 tumor antigen-specific TCR and its humanized derivative is governed by the CD8 coreceptor and affects natural human TCR expression

scientific article published on January 2006

Reduced-intensity conditioning followed by allografting of CD34-selected stem cells and < or =10(6)/kg T cells may have an adverse effect on transplant-related mortality

scientific article

Repositionable Versus Balloon-Expandable Devices for Transcatheter Aortic Valve Implantation in Patients With Aortic Stenosis

scientific article

Response To Letter Regarding Article, "Effect of Pulmonary Hypertension Hemodynamic Presentation on Clinical Outcomes in Patients With Severe Symptomatic Aortic Valve Stenosis Undergoing Transcatheter Aortic Valve Implantation: Insights From the New

scientific article published in September 2015

Results of a multicenter phase II trial for older patients with c-Kit-positive acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (HR-MDS) using low-dose Ara-C and Imatinib

scientific article published in March 2007

Second valve implantation for the treatment of a malpositioned transcatheter aortic valve

scientific article published in September 2012

Selective activation of trophoblast-specific PLAC1 in breast cancer by CCAAT/enhancer-binding protein beta (C/EBPbeta) isoform 2.

scientific article published on 03 August 2009

Selective activation of tumor growth-promoting Ca2+ channel MS4A12 in colon cancer by caudal type homeobox transcription factor CDX2.

scientific article published on 25 September 2009

Selective depletion of alloreactive T lymphocytes using patient-derived nonhematopoietic stimulator cells in allograft engineering

scientific article published in November 2008

SeroGRID: an improved method for the rapid selection of antigens with disease related immunogenicity.

scientific article

Short-term clinical outcomes among patients undergoing transcatheter aortic valve implantation in Switzerland: the Swiss TAVI registry

scholarly article by Peter Wenaweser et al published December 2014 in EuroIntervention

Simplified Approach for Repair of Early Pseudoaneurysm of the Left Coronary Button Following Composite Graft Due to Acute Type A Aortic Dissection

scientific article published on December 2016

Simultaneous ex vivo quantification of antigen-specific CD4+ and CD8+ T cell responses using in vitro transcribed RNA

article

Successful adenovirus-mediated wild-type p53 gene transfer in patients with bladder cancer by intravesical vector instillation

article

Superior antitumor in vitro responses of allogeneic matched sibling compared with autologous patient CD8+ T cells

scientific article published on December 2006

Surgical antegrade transcatheter mitral valve implantation for symptomatic mitral valve disease and heavily calcified annulus

scientific article published on 01 February 2017

Sustained complete hematologic remission after administration of the tyrosine kinase inhibitor imatinib mesylate in a patient with refractory, secondary AML.

scientific article published on 12 December 2002

Sustained complete molecular remissions after treatment with imatinib-mesylate in patients with failure after allogeneic stem cell transplantation for chronic myelogenous leukemia: results of a prospective phase II open-label multicenter study

scientific article published in October 2005

Sustained remissions and low rate of BCR-ABL resistance mutations with imatinib treatment chronic myelogenous leukemia in patients treated in late chronic phase: a 5-year follow up

scientific article published on 01 March 2008

Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy

scientific article (publication date: June 2016)

Targeting AKT signaling sensitizes cancer to cellular immunotherapy

scientific article

Targeting BCL-2 family proteins to overcome drug resistance in non-small cell lung cancer

scientific article published on December 2007

Targeting positive regulatory domain I-binding factor 1 and X box-binding protein 1 transcription factors by multiple myeloma-reactive CTL

scientific article

Targeting the Heterogeneity of Cancer with Individualized Neoepitope Vaccines.

scientific article published on April 2016

Targeting the activation-induced antigen CD137 can selectively deplete alloreactive T cells from antileukemic and antitumor donor T-cell lines

scientific article

Temporal Trends in Adoption and Outcomes of Transcatheter Aortic Valve Implantation: A Swisstavi Registry Analysis

scientific article published on 01 July 2019

The European Regulatory Environment of RNA-Based Vaccines

scientific article published on January 2017

The hospital results and 1-year outcomes of transcatheter aortic valve-in-valve procedures and transcatheter aortic valve implantations in the native valves: the results from the Swiss-TAVI Registry

scientific article published on 01 July 2019

The human X chromosome is enriched for germline genes expressed in premeiotic germ cells of both sexes.

scientific article

The kinase inhibitor LS104 induces apoptosis, enhances cytotoxic effects of chemotherapeutic drugs and is targeting the receptor tyrosine kinase FLT3 in acute myeloid leukemia

scientific article published on 16 June 2008

The regulatory landscape for actively personalized cancer immunotherapies

article published in 2013

The response of autologous T cells to a human melanoma is dominated by mutated neoantigens

scientific article

The role of the reporting framework MIATA within current efforts to advance immune monitoring

scholarly article by Sylvia Janetzki et al published July 2014 in Journal of Immunological Methods

The self-expanding Symetis Acurate does not increase cerebral microembolic load when compared to the balloon-expandable Edwards Sapien prosthesis: a transcranial Doppler study in patients undergoing transapical aortic valve implantation

scientific article

The use of clonal mRNA as an antigenic format for the detection of antigen-specific T lymphocytes in IFN-gamma ELISPOT assays

scientific article published in April 2004

Therapeutic vaccines for cancer: an overview of clinical trials

scientific article published on 08 July 2014

Transapical transcatheter aortic valve implantation using the second-generation self-expanding Symetis ACURATE TA valve.

scientific article published on 8 October 2014

Transcarotid aortic valve-in-valve implantation for degenerated stentless aortic root conduits with severe regurgitation: a case series

scientific article published on 15 March 2015

Transcatheter aortic valve implantation or surgical aortic valve replacement as redo procedure after prior coronary artery bypass grafting

scientific article published on 31 August 2011

Transcranial Doppler-detected cerebral embolic load during transcatheter aortic valve implantation

scientific article published in December 2011

Transporter (TAP)‐ and proteasome‐independent presentation of a melanoma‐associated tyrosinase epitope

Validation of 3D-reconstructed computed tomography images using OsiriX® software for pre-transcatheter aortic valve implantation aortic annulus sizing

scientific article published on 8 May 2017

Validation of the Valve Academic Research Consortium Bleeding Definition in Patients With Severe Aortic Stenosis Undergoing Transcatheter Aortic Valve Implantation.

scientific article published on 25 September 2015

mTOR inhibition improves antitumor effects of vaccination with antigen-encoding RNA.

scientific article published on 20 September 2013

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