List of works by Clement C. Zai

A common polymorphism in the cannabinoid receptor 1 (CNR1) gene is associated with antipsychotic-induced weight gain in Schizophrenia

scientific article

A contribution of novel CNVs to schizophrenia from a genome-wide study of 41,321 subjects

A hypothesis-driven association study of 28 nuclear-encoded mitochondrial genes with antipsychotic-induced weight gain in schizophrenia

scientific article

A psycho-genetic study of associations between the symptoms of binge eating disorder and those of attention deficit (hyperactivity) disorder

scientific article published on 28 November 2008

Admixture analysis of age at onset in schizophrenia: genetic association study of 45 candidate loci

scientific article published on 20 December 2011

An examination of genes, stress and suicidal behavior in two First Nations communities: The role of the brain-derived neurotropic factor gene

scientific article published on 18 February 2019

Analysis of 34 candidate genes in bupropion and placebo remission

scientific article published on 4 September 2012

Analysis of CpG SNPs in 34 genes: association test with suicide attempt in schizophrenia.

scientific article published on 14 May 2013

Analysis of treatment-resistant schizophrenia and 384 markers from candidate genes

scientific article

Antidepressant-Associated Mania in Bipolar Disorder: A Review and Meta-analysis of Potential Clinical and Genetic Risk Factors

scientific article published on 01 March 2020

Association Study of Serotonin 3 Receptor Subunit Gene Variants in Antipsychotic-Induced Weight Gain

scientific article published on 23 May 2017

Association Study of the Complement Component C4 Gene in Tardive Dyskinesia

scientific article published on 26 November 2019

Association between the -2548G/A polymorphism of the leptin gene and antipsychotic-induced weight gain: Analysis of the CATIE sample and meta-analysis

scientific article published on 23 April 2020

Association of a functional polymorphism in neuropeptide Y with antipsychotic-induced weight gain in schizophrenia patients.

scientific article published in February 2013

Association of orexin receptor polymorphisms with antipsychotic-induced weight gain

scientific article published on 8 October 2015

Association of polymorphisms in the BDNF, DRD1 and DRD3 genes with tobacco smoking in schizophrenia

scientific article published on 25 April 2010

Association of the alpha 2A adrenergic receptor -1291C/G polymorphism and antipsychotic-induced weight gain in European-Americans.

scientific article published in July 2009

Association of the orphan nuclear receptor NR4A1 with tardive dyskinesia

scientific article

Association study between the neurexin-1 gene and tardive dyskinesia

scientific article published in January 2017

Association study of BDNF and DRD3 genes in schizophrenia diagnosis using matched case-control and family based study designs.

scientific article published on 24 July 2010

Association study of Disrupted-In-Schizophrenia-1 gene variants and tardive dyskinesia

scientific article published on 15 August 2018

Association study of GABAA α2 receptor subunit gene variants in antipsychotic-associated weight gain

scientific article published in February 2015

Association study of GABRG2 polymorphisms with suicidal behaviour in schizophrenia patients with alcohol use disorder

scientific article

Association study of GRIK1 gene polymorphisms in schizophrenia: case-control and family-based studies

scientific article published on 22 June 2012

Association study of polymorphisms in cholecystokinin gene and its receptors with antipsychotic induced weight gain in schizophrenia patients

scientific article published on 20 August 2010

Association study of polymorphisms in insulin induced gene 2 (INSIG2) with antipsychotic-induced weight gain in European and African-American schizophrenia patients

scientific article published in April 2010

Association study of tardive dyskinesia and twelve DRD2 polymorphisms in schizophrenia patients

scientific article published on 7 September 2006

Association study of the gamma-aminobutyric acid type a receptor gamma2 subunit gene with schizophrenia

scientific article published on 13 August 2009

Association study of the vesicular monoamine transporter gene SLC18A2 with tardive dyskinesia

scientific article

BDNF Val66Met polymorphism and clinical response to antipsychotic treatment in schizophrenia and schizoaffective disorder patients: a meta-analysis

scientific article published on 05 September 2018

Catechol-O-Methyltransferase Val158Met Polymorphism and Clinical Response to Antipsychotic Treatment in Schizophrenia and Schizo-Affective Disorder Patients: a Meta-Analysis

scientific article published on 8 January 2016

Childhood trauma predicts multiple, high lethality suicide attempts in patients with schizophrenia

scientific article published on 13 September 2019

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

scientific article

Copy number variant syndromes are frequent in schizophrenia: Progressing towards a CNV-schizophrenia model

scientific article published on 10 May 2019

Corrigendum to “Summary of the 1st Schizophrenia International Research Society Conference oral sessions, Venice, Italy, June 21–25, 2008: The rapporteur reports”

article

DNA methylation and clinical response to antidepressant medication in major depressive disorder: A review and recommendations

scientific article published on 4 January 2017

DRD4 VNTR polymorphism and age at onset of severe mental illnesses

scientific article published on 20 April 2012

Does a history of violence predict higher antipsychotic dosage in schizophrenia?

scientific article published on 17 January 2019

Dopamine D4 and D5 receptor gene variant effects on clozapine response in schizophrenia: replication and exploration

scientific article published on 8 December 2011

Early onset schizophrenia: Gender analysis of genome-wide potential methylation

scientific article published on April 2015

Early-life stressful events and suicide attempt in schizophrenia: Machine learning models

scientific article published on 20 January 2020

Epigenome-wide association study of suicide attempt in schizophrenia

scientific article published on 20 July 2018

Ethical and Policy Considerations in the Application of Pharmacogenomic Testing for Tardive Dyskinesia: Case Study of the Dopamine D3 Receptor

scientific article published on June 2011

F1. GENOME-WIDE ASSOCIATION STUDIES SUGGESTED ASSOCIATION BETWEEN DGKB AND ANTIPSYCHOTIC INDUCED WEIGHT GAIN IN EUROPEANS AND AFRICAN AMERICANS.

scientific article

FKBP5 interacts with maltreatment in children with extreme, pervasive, and persistent aggression

scientific article published on 7 June 2016

Fat mass- and obesity-associated (FTO) gene and antipsychotic-induced weight gain: an association study

scientific article published on 30 January 2014

Finite mixture regression model analysis on antipsychotics induced weight gain: investigation of the role of the serotonergic genes

scientific article published on 26 July 2012

GWAS analysis of suicide attempt in schizophrenia: Main genetic effect and interaction with early life trauma

scientific article

GWAS analysis of treatment resistant schizophrenia: interaction effect of childhood trauma

scientific article published on 28 April 2017

Genetic Factors and Suicidal Behavior

Genetic association and post-mortem brain mRNA analysis of DISC1 and related genes in schizophrenia

scientific article published on 24 July 2009

Genetic interactions in the adrenergic system genes: analysis of antipsychotic-induced weight gain

scientific article published on 8 August 2011

Genetic study of BDNF, DRD3, and their interaction in tardive dyskinesia

scientific article published on 13 February 2009

Genetic study of eight AKT1 gene polymorphisms and their interaction with DRD2 gene polymorphisms in tardive dyskinesia

scientific article published on 5 October 2008

Genetic study of neuregulin 1 and receptor tyrosine-protein kinase erbB-4 in tardive dyskinesia

scientific article

Genetic validation study of protein tyrosine phosphatase receptor type D (PTPRD) gene variants and risk for antipsychotic-induced weight gain

scientific article published on 18 September 2018

Genetic variation in the GCG and in the GLP1R genes and antipsychotic-induced weight gain

scientific article published in March 2014

Genetics of human startle reactivity: A systematic review to acquire targets for an anxiety endophenotype

scientific article published on 12 October 2020

Genetics of tardive dyskinesia: Promising leads and ways forward.

scientific article published on 5 February 2018

Genome-Wide Association Study of Sleep Disturbances in Depressive Disorders

scientific article published on 08 January 2020

Genome-wide association analysis to predict optimal antipsychotic dosage in schizophrenia: a pilot study

scientific article published on 28 January 2016

Genome-wide association study of aggression and violence in schizophrenia

scientific article published on 20 May 2020

Genome-wide association study on antipsychotic-induced weight gain in Europeans and African-Americans

scientific article published on 22 August 2019

Genome-wide methylation association with current suicidal ideation in schizophrenia

scientific article published on 13 July 2020

Genomic dissection of bipolar disorder and schizophrenia including 28 subphenotypes

scientific article published on 8 August 2017

Impact of histamine receptors H1 and H3 polymorphisms on antipsychotic-induced weight gain

scientific article published on 18 November 2016

Independent effect of childhood trauma and recent stress as predictors for current suicidal ideation in schizophrenia

scientific article published on 24 October 2019

Interaction between Methylation and CpG Single-Nucleotide Polymorphisms in the HTR2A Gene: Association Analysis with Suicide Attempt in Schizophrenia

scientific article published on 27 January 2016

Investigation of TSPO variants in schizophrenia and antipsychotic treatment outcomes

scientific article published on January 2015

Investigation of accelerated epigenetic aging in individuals experiencing suicidal ideation

scientific article published on 09 October 2020

Investigation of the Gene in Tardive Dyskinesia - New Data and Meta-Analysis

article

Lack of association between dopamine-β hydroxylase gene and a history of suicide attempt in schizophrenia: comparison of molecular and statistical haplotype analyses

scientific article

Linkage study of two polymorphisms at the dopamine D3 receptor gene and attention-deficit hyperactivity disorder

article

Liver enzyme CYP2D6 gene and tardive dyskinesia

scientific article published on 24 September 2020

MDR1 gene in tardive dyskinesia scale scores: comparison of strategies for quantitative trait haplotype analysis.

scientific article published on 17 March 2009

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

scientific article published on 8 April 2022

Maternal immune activation during gestation interacts with Disc1 point mutation to exacerbate schizophrenia-related behaviors in mice.

scientific article published in May 2013

Multiple tissue methylation analysis of HTR2A exon I in suicidal behavior

scientific article published in December 2017

New findings in pharmacogenetics of schizophrenia.

scientific article published on 9 March 2018

New insights into tardive dyskinesia genetics: Implementation of whole-exome sequencing approach

scientific article published on 30 May 2019

No evidence for a role of the peroxisome proliferator-activated receptor gamma (PPARG) and adiponectin (ADIPOQ) genes in antipsychotic-induced weight gain

scientific article

Oligodendrocyte genes, white matter tract integrity, and cognition in schizophrenia

scientific article

Oxidative stress in tardive dyskinesia: genetic association study and meta-analysis of NADPH quinine oxidoreductase 1 (NQO1) and Superoxide dismutase 2 (SOD2, MnSOD) genes

scientific article published on 22 September 2009

PM389. Preliminary Genetic Model Predicting Clozapine Response.

scientific article published on 27 May 2016

Peripheral Biomarkers in Schizophrenia: A Meta-Analysis of Microarray Gene Expression Datasets

scientific article published on 01 March 2019

Polymorphisms of the HTR2C gene and antipsychotic-induced weight gain: an update and meta-analysis

scientific article published in November 2010

Predicting risk of suicidal ideation in youth using a multigene panel for impulsive aggression

scientific article published on 02 December 2019

Preliminary evidence for association of genome-wide significant DRD2 schizophrenia risk variant with clozapine response

scientific article published on 15 December 2015

Proof-of-concept study of a multi-gene risk score in adolescent bipolar disorder

scientific article published on 05 November 2019

Recent health-related stressful life events predictive of emergent suicidal ideation in schizophrenia

scientific article published on 11 January 2019

Role of 5-HT(2C) receptor gene variants in antipsychotic-induced weight gain

scientific article

Role of ethnicity in antipsychotic-induced weight gain and tardive dyskinesia: genes or environment?

scientific article

S191. INVESTIGATION OF THE PREVALENCE OF COPY NUMBER VARIANT SYNDROMES IN A LARGE SCHIZOPHRENIA COHORT.

scientific article published in April 2018

S222. CLINICAL UTILITY OF PHARMACOGENETIC TESTING IN SCHIZOPHRENIA TREATMENT.

scientific article

SU3. Preliminary Study for Association of Genome-Wide Significant Glutamate Receptor Schizophrenia Risk Variants With Clozapine Response.

scientific article

Schizophrenia-associated gene dysbindin-1 and tardive dyskinesia

scientific article published on 11 May 2020

Sequence Analysis of Drug Target Genes with Suicidal Behavior in Bipolar Disorder Patients

scientific article published on 03 May 2018

Specific Alterations in Astrocyte Properties via the GluA2-GAPDH Complex Associated with Multiple Sclerosis

scientific article published in Scientific Reports

Summaries from the XIX World Congress of Psychiatric Genetics, Washington, DC, September 10-14, 2011.

scientific article published on January 2012

Summary of the 1st Schizophrenia International Research Society Conference oral sessions, Venice, Italy, June 21-25, 2008: the rapporteur reports

scientific article published on 26 September 2008

T11. THE STRUCTURAL VARIANTS OF COMPLEMENT COMPONENT (C4) IN THE RISK AND CLINICAL CHARACTERISTICS OF SCHIZOPHRENIA

T7. PHARMACOGENETIC OF TARDIVE DYSKINESIA -- A FOLLOW-UP ON THE VALBENAZINE TARGET VMAT2/SLC18A2.

scientific article published in April 2018

The AmpliChip® CYP450 test and response to treatment in schizophrenia and obsessive compulsive disorder: a pilot study and focus on cases with abnormal CYP2D6 drug metabolism

scientific article

The Effects of Age and Sex on the Interaction Between Monoamine Oxidase A VNTR and Psychopathic Traits in Children and Adolescents

scientific article published in 2021

The Role of the Catechol-o-Methyltransferase (COMT) GeneVal158Met in Aggressive Behavior, a Review of Genetic Studies

scientific article published on November 2015

The brain-derived neurotrophic factor gene in suicidal behaviour: a meta-analysis

scientific article published on 30 August 2011

The catechol-O-methyl-transferase gene in tardive dyskinesia

scientific article published in September 2010

The effect of ethnicity and immigration on treatment resistance in schizophrenia

scientific article published on 07 December 2018

The effect of polymorphisms in startle-related genes on anxiety symptom severity

scientific article published on 03 April 2020

The pharmacogenetics of antipsychotic-induced adverse events

scientific article

The pharmacogenetics of opioid treatment for pain management

scientific article published on 25 July 2020

The role of brain-derived neurotrophic factor (BDNF) gene variants in antipsychotic response and antipsychotic-induced weight gain

scientific article published on 27 May 2012

The role of tyrosine hydroxylase gene variants in suicide attempt in schizophrenia.

scientific article published on 23 November 2013

Towards precision medicine in generalized anxiety disorder: Review of genetics and pharmaco(epi)genetics

scientific article published on 06 September 2019

Use of candidate gene markers to guide antipsychotic dosage adjustment

scientific article

Weak association of the platelet-derived growth factor beta (PDGFB) and PDGF receptor beta (PDGFRB) genes with schizophrenia and schizoaffective disorder

scientific article published on October 18, 2010