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List of works by Vassiliki Papadimitrakopoulou

24-Month Overall Survival From KEYNOTE-021 Cohort G: Pemetrexed and Carboplatin With or Without Pembrolizumab As First-Line Therapy for Advanced Nonsquamous Non-Small-Cell Lung Cancer

article by Hossein Borghaei et al published 20 August 2018 in Journal of Thoracic Oncology

A Phase II study of docetaxel and carboplatin as neoadjuvant therapy for nasopharyngeal carcinoma with early T status and advanced N status

scientific article published in March 2004

A phase I/II study of neoadjuvant chemotherapy followed by radiation with boost chemotherapy for advanced T-stage nasopharyngeal carcinoma

scientific article

AURA3 trial: does Tagrisso (osimertinib) have the potential to become the new standard of care for second-line treatment of patients with EGFR T790M mutation-positive locally advanced or metastatic NSCLC

scientific article published on 01 December 2016

Akt activation correlates with adverse outcome in tongue cancer

article

An Integrated Next-Generation Sequencing System for Analyzing DNA Mutations, Gene Fusions, and RNA Expression in Lung Cancer

article

An attenuated adenovirus, ONYX-015, as mouthwash therapy for premalignant oral dysplasia.

scientific article published on 3 November 2003

Atezolizumab in combination with bevacizumab, paclitaxel and carboplatin for the first-line treatment of patients with metastatic non-squamous non-small cell lung cancer, including patients with EGFR mutations

scientific article published on 12 December 2019

Author Correction: Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer

scientific article published in Nature Communications

Bayesian Two-stage Biomarker-based Adaptive Design for Targeted Therapy Development

scientific article published on 04 December 2014

Biologic correlates of a biochemoprevention trial in advanced upper aerodigestive tract premalignant lesions

scientific article

CD38-Mediated Immunosuppression as a Mechanism of Tumor Cell Escape from PD-1/PD-L1 Blockade

scientific article published on 16 July 2018

CNS Efficacy of Osimertinib in Patients With T790M-Positive Advanced Non-Small-Cell Lung Cancer: Data From a Randomized Phase III Trial (AURA3)

scientific article published on 30 July 2018

Carboplatin and pemetrexed with or without pembrolizumab for advanced, non-squamous non-small-cell lung cancer: a randomised, phase 2 cohort of the open-label KEYNOTE-021 study.

scientific article

Challenges and approaches to implementing master/basket trials in oncology

scientific article published on 01 July 2019

Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer

scientific article published in Nature Communications

Clinical Utility of Comprehensive Cell-free DNA Analysis to Identify Genomic Biomarkers in Patients with Newly Diagnosed Metastatic Non-small Cell Lung Cancer

scientific article published on 15 April 2019

Clinician Perspectives on Current Issues in Lung Cancer Drug Development.

scientific article

Clinicopathologic and genetic features of primary bronchopulmonary mucoepidermoid carcinoma: the MD Anderson Cancer Center experience and comprehensive review of the literature.

scientific article published on 25 March 2017

Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities

scientific article

Combination Treatment with MEK and AKT Inhibitors Is More Effective than Each Drug Alone in Human Non-Small Cell Lung Cancer In Vitro and In Vivo ⬇️

scientific article published on November 29, 2010

Comparison of 2 common radiation therapy techniques for definitive treatment of small cell lung cancer

scientific article published in September 2013

Computed tomography RECIST assessment of histopathologic response and prediction of survival in patients with resectable non-small-cell lung cancer after neoadjuvant chemotherapy

scientific article published on February 2013

Concomitant targeting of the mTOR/MAPK pathways: novel therapeutic strategy in subsets of -altered non-small cell lung cancer

Concordance of oral HPV prevalence between patients with oropharyngeal cancer and their partners

scientific article published on 27 April 2016

Cyclin D1 and cancer development in laryngeal premalignancy patients

scientific article

Cyclin D1 genotype, response to biochemoprevention, and progression rate to upper aerodigestive tract cancer

scientific article

De novo lipogenesis represents a therapeutic target in mutant Kras non-small cell lung cancer

scientific article published on 15 June 2018

Defining tumor resistance to PD-1 pathway blockade: recommendations from the first meeting of the SITC Immunotherapy Resistance Taskforce

scientific article published on 01 March 2020

Development of PI3K/AKT/mTOR Pathway Inhibitors and Their Application in Personalized Therapy for Non–Small-Cell Lung Cancer ⬇️

scientific article published on August 1, 2012

Dose-dense therapy with a novel irinotecan regimen for small-cell lung cancer

scientific article published in July 2003

Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome

scientific article

Effects of amifostine on acute toxicity from concurrent chemotherapy and radiotherapy for inoperable non-small-cell lung cancer: report of a randomized comparative trial

scientific article published on April 2004

Epidermal growth factor receptor expression and gene copy number in the risk of oral cancer

scientific article

Epidermal growth factor receptor inhibitors in development for the treatment of non-small cell lung cancer

scientific article published on July 2006

Epidermal growth factor receptor mutation analysis in tissue and plasma from the AURA3 trial: Osimertinib versus platinum-pemetrexed for T790M mutation-positive advanced non-small cell lung cancer

scientific article published on 26 November 2019

Epithelial-Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma

scientific article published on 5 February 2016

Erlotinib and the Risk of Oral Cancer: The Erlotinib Prevention of Oral Cancer (EPOC) Randomized Clinical Trial.

scientific article published on 5 November 2015

Everolimus and Erlotinib as Second- or Third-Line Therapy in Patients with Advanced Non–Small-Cell Lung Cancer ⬇️

scientific article published on October 1, 2012

Excerpts from the 1st international NTNU symposium on current and future clinical biomarkers of cancer: innovation and implementation, June 16th and 17th 2016, Trondheim, Norway

scientific article published on 19 October 2016

Feasibility of adding everolimus to carboplatin and paclitaxel, with or without bevacizumab, for treatment-naive, advanced non-small cell lung cancer

scientific article

Fenretinide activity in retinoid-resistant oral leukoplakia

scientific article published on 01 May 2006

Focus on head and neck cancer

scientific article published on April 2004

Gene expression profiling predicts the development of oral cancer.

scientific article

High-dose fenretinide in oral leukoplakia

scientific article

Immunotherapy in Non-Small Cell Lung Cancer Treatment: Current Status and the Role of Imaging

scientific article published on 3 August 2017

Immunotherapy in lung cancer

scientific article published in February 2014

Induction chemotherapy and cetuximab for locally advanced squamous cell carcinoma of the head and neck: results from a phase II prospective trial

scientific article

Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy.

scientific article published in January 2003

Intraarterial cisplatin with intravenous paclitaxel and ifosfamide as an organ-preservation approach in patients with paranasal sinus carcinoma

scientific article published in November 2003

JAK1/STAT3 activation through a proinflammatory cytokine pathway leads to resistance to molecularly targeted therapy in non-small cell lung cancer

scientific article published on 20 July 2017

Landscape of EGFR-Dependent and -Independent Resistance Mechanisms to Osimertinib and Continuation Therapy Beyond Progression in EGFR-Mutant NSCLC

scientific article published on 18 September 2018

Local Consolidation Therapy (LCT) After First Line Tyrosine Kinase Inhibitor (TKI) for Patients With EGFR Mutant Metastatic Non-small-cell Lung Cancer (NSCLC)

scientific article published on 24 September 2018

Locoregional Control, Overall Survival, and Disease-Free Survival in Stage IIIA (N2) Non-Small-Cell Lung Cancer: Analysis of Resected and Unresected Patients

scientific article published on 27 January 2020

Long-Term, Prospective Performance of the MD Anderson Dysphagia Inventory in "Low-Intermediate Risk" Oropharyngeal Carcinoma After Intensity Modulated Radiation Therapy.

scientific article published on 15 June 2016

Loss of E-cadherin and p27 expression is associated with head and neck squamous tumorigenesis

scientific article published on 01 March 2005

Lung Master Protocol (Lung-MAP)-A Biomarker-Driven Protocol for Accelerating Development of Therapies for Squamous Cell Lung Cancer: SWOG S1400.

scientific article

Lung-MAP--framework, overview, and design principles

scientific article

Master protocols in lung cancer: experience from Lung Master Protocol

scientific article published on 10 January 2018

Mechanisms and clinical activity of an EGFR and HER2 exon 20-selective kinase inhibitor in non-small cell lung cancer.

scientific article published on 23 April 2018

Met Receptor Tyrosine Kinase and Chemoprevention of Oral Cancer.

scientific article published in March 2018

Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations

scientific article published on 16 December 2015

Mutations and PD-1 Inhibitor Resistance in -Mutant Lung Adenocarcinoma

scientific article published on 17 May 2018

New Treatment Options in Advanced Squamous Cell Lung Cancer

scientific article published on 01 January 2019

Non-Small Cell Lung Cancer beyond Biomarkers: The Evolving Landscape of Clinical Trial Design

scientific article

Optimizing Biomarkers and Endpoints in Oral Cancer Chemoprevention Trials ⬇️

scientific article published on May 1, 2013

Osimertinib in EGFR T790M–Positive Lung Cancer

scientific article published on 01 May 2017

Osimertinib or Platinum-Pemetrexed in EGFR T790M-Positive Lung Cancer.

scientific article published on 6 December 2016

Outcomes of patients with tonsillar carcinoma treated with post-tonsillectomy radiation therapy

scientific article published in April 2010

PD-L1 Expression, Tumor Mutational Burden, and Cancer Gene Mutations Are Stronger Predictors of Benefit from Immune Checkpoint Blockade than HLA Class I Genotype in Non-Small Cell Lung Cancer

scientific article published on 16 February 2019

PS01.53: First-Line Atezolizumab Plus Chemotherapy in Chemotherapy-Naive Patients with Advanced NSCLC: A Phase III Clinical Program: Topic: Medical Oncology.

scientific article

Patient-reported symptoms possibly related to treatment with osimertinib or chemotherapy for advanced non-small cell lung cancer

scientific article published on 07 May 2018

Pembrolizumab and platinum-based chemotherapy as first-line therapy for advanced non-small-cell lung cancer: Phase 1 cohorts from the KEYNOTE-021 study

scientific article published on 25 August 2018

Pembrolizumab in Combination With Erlotinib or Gefitinib as First-Line Therapy for Advanced NSCLC With Sensitizing EGFR Mutation

scientific article published on 04 December 2018

Personalized Medicine Tackles Clinical Resistance: Alectinib in ALK-Positive Non-Small Cell Lung Cancer Progressing on First-Generation ALK Inhibitor

scientific article published on 8 September 2016

Pharmacokinetic study of the phase III, randomized, double-blind, multicenter trial (TRIBUTE) of paclitaxel and carboplatin combined with erlotinib or placebo in patients with advanced Non-small Cell Lung Cancer (NSCLC)

scientific article published on 22 January 2010

Phase 2 study of dasatinib in the treatment of head and neck squamous cell carcinoma ⬇️

scientific article published on November 29, 2010

Phase I Study of Weekly Alternating Therapy with Irinotecan/Cisplatin and Etoposide/Cisplatin for Patients with Small-Cell Lung Cancer ⬇️

scientific article published on July 1, 2003

Phase I Trial of Pembrolizumab and Radiation Therapy after Induction Chemotherapy for Extensive-Stage Small Cell Lung Cancer

scientific article published on 09 October 2019

Phase I pharmacokinetic and pharmacodynamic study of the oral mammalian target of rapamycin inhibitor everolimus in patients with advanced solid tumors

scientific article

Phase I/II study of docetaxel, cisplatin, and concomitant boost radiation for locally advanced squamous cell cancer of the head and neck

scientific article published on 01 September 2006

Phase II Trial of Ipilimumab with Stereotactic Radiation Therapy for Metastatic Disease: Outcomes, Toxicities, and Low-Dose Radiation-Related Abscopal Responses

scientific article published on 28 October 2019

Phase II Trials of Imatinib Mesylate and Docetaxel in Patients with Metastatic Non-small Cell Lung Cancer and Head and Neck Squamous Cell Carcinoma ⬇️

scientific article published on December 1, 2011

Phase II randomized, placebo-controlled trial of green tea extract in patients with high-risk oral premalignant lesions

scientific article

Phase II study of induction chemotherapy with paclitaxel, ifosfamide, and carboplatin (TIC) for patients with locally advanced squamous cell carcinoma of the head and neck

scientific article

Phase II study of pemetrexed in combination with carboplatin in the first-line treatment of advanced nonsmall cell lung cancer

scientific article

Phase II trial of the histone deacetylase inhibitor vorinostat (Zolinza, suberoylanilide hydroxamic acid, SAHA) in patients with recurrent and/or metastatic head and neck cancer

scientific article

Phosphatidykinosital 3-Kinase and Mammalian Target of Rapamycin Pathway in Non–Small-Cell Lung Cancer ⬇️

scientific article published on December 1, 2012

Pilot randomized phase II study of celecoxib in oral premalignant lesions

scientific article

Postoperative radiotherapy for maxillary sinus cancer: long-term outcomes and toxicities of treatment

scientific article published on 01 July 2007

Predictive biomarkers of response to PD-1/PD-L1 immune checkpoint inhibitors in non-small cell lung cancer

scientific article

Randomized trial of 13-cis retinoic acid compared with retinyl palmitate with or without beta-carotene in oral premalignancy

scientific article published on 15 December 2008

Randomized, double-blind, placebo-controlled phase IIb trial of the cyclooxygenase inhibitor ketorolac as an oral rinse in oropharyngeal leukoplakia

scientific article published in March 2004

Rociletinib in EGFR-mutated non-small-cell lung cancer

scientific article

Role of cyclooxygenase-2 in tumor progression and survival of head and neck squamous cell carcinoma

scientific article

STING Pathway Expression Identifies NSCLC With an Immune-Responsive Phenotype

scientific article published on 15 February 2020

SWOG S1400B (NCT02785913), a Phase II Study of GDC-0032 (Taselisib) for Previously Treated PI3K-Positive Patients with Stage IV Squamous Cell Lung Cancer (Lung-MAP Sub-Study)

scientific article published on 31 May 2019

SWOG S1400C (NCT02154490)-A Phase II Study of Palbociclib for Previously Treated Cell Cycle Gene Alteration-Positive Patients with Stage IV Squamous Cell Lung Cancer (Lung-MAP Substudy)

scientific article published on 11 July 2019

SWOG S1400D (NCT02965378), a Phase II Study of the Fibroblast Growth Factor Receptor Inhibitor AZD4547 in Previously Treated Patients With Fibroblast Growth Factor Pathway-Activated Stage IV Squamous Cell Lung Cancer (Lung-MAP Substudy)

scientific article published on 11 June 2019

Scientific Advances in Lung Cancer 2015.

scientific article published on 21 March 2016

TNF-driven adaptive response mediates resistance to EGFR inhibition in lung cancer

scientific article published on 3 April 2018

Targeted Therapy and Imaging Findings.

scientific article

Targeted Therapy and Immunotherapy in the Treatment of Non-Small Cell Lung Cancer

scientific article published in May 2018

Targeted Tissue and Cell-Free Tumor DNA Sequencing of Advanced Lung Squamous-Cell Carcinoma Reveals Clinically Significant Prevalence of Actionable Alterations

Targeting the Gatekeeper: Osimertinib in EGFR T790M Mutation-Positive Non-Small Cell Lung Cancer

scientific article published on 7 November 2016

The Akt/mTOR and mitogen-activated protein kinase pathways in lung cancer therapy.

scientific article published on September 2006

The BATTLE trial: personalizing therapy for lung cancer

scientific article

The BATTLE-2 Study: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer

scientific article published on August 2016

The Importance of Molecular Profiling in Predicting Response to Epidermal Growth Factor Receptor Family Inhibitors in Non–Small-Cell Lung Cancer: Focus on Clinical Trial Results ⬇️

scientific article published on April 11, 2013

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of non-small cell lung cancer (NSCLC).

scientific article published on 17 July 2018

The future of NSCLC: molecular profiles guiding treatment decisions.

scientific article published on June 2011

The novel and effective nonplatinum, nontaxane combination of gemcitabine and vinorelbine in advanced nonsmall cell lung carcinoma: potential for decreased toxicity and combination with biological therapy

scientific article

The prognostic role of loss of insulin-like growth factor-binding protein-3 expression in head and neck carcinogenesis

scientific article published on 21 September 2005

Uncommon Epidermal Growth Factor Receptor mutations in non-small cell lung cancer and their mechanisms of EGFR tyrosine kinase inhibitors sensitivity and resistance ⬇️

scientific article published on February 26, 2013

Validation of the 12-gene predictive signature for Adjuvant Chemotherapy Response in Lung Cancer

article

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