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List of works by Marcus J Schultz

"Why, sometimes I've believed as many as six impossible things before breakfast." Lewis Carroll, In "Through the looking-glass, and what Alice found there".

scientific article

A Molecular Host Response Assay to Discriminate Between Sepsis and Infection-Negative Systemic Inflammation in Critically Ill Patients: Discovery and Validation in Independent Cohorts

scientific article

A change in the Dutch Directive on Medical Research Involving Human Subjects strongly increases the number of eligible intensive care patients: an observational study

scientific article published on 01 November 2006

A comparison of RIFLE with and without urine output criteria for acute kidney injury in critically ill patients

scientific article published on 18 October 2012

A molecular biomarker to diagnose community-acquired pneumonia on intensive care unit admission

scientific article published on 29 June 2015

A new prediction score for critically ill patients-do we need an Apgar score for acute respiratory distress syndrome?

scientific article published on February 2017

A new twist on the legend of granulocyte colony-stimulating factor in acute lung injury?

scientific article published in April 2009

A short course of infusion of a hydrogen sulfide-donor attenuates endotoxemia induced organ injury via stimulation of anti-inflammatory pathways, with no additional protection from prolonged infusion

scientific article

A simple breath sampling method in intubated and mechanically ventilated critically ill patients.

scientific article

A systematic review on quality indicators for tight glycaemic control in critically ill patients: need for an unambiguous indicator reference subset

scientific article

ARDS: challenges in patient care and frontiers in research.

scientific article published on 24 January 2018

Accuracy and limitations of continuous glucose monitoring using spectroscopy in critically ill patients

scientific article

Activated protein C in the treatment of acute lung injury and acute respiratory distress syndrome ⬇️

scientific article published on March 1, 2009

Acute coagulopathy of trauma: hypoperfusion induces systemic anticoagulation and hyperfibrinolysis

scientific article published on 01 May 2008

Acute pancreatitis in mice impairs bacterial clearance from the lungs, whereas concurrent pneumonia prolongs the course of pancreatitis

scientific article

Acute phase response impairs host defense against Pseudomonas aeruginosa pneumonia in mice

scientific article published in February 2008

Adaptive Support Ventilation May Deliver Unwanted Respiratory Rate–Tidal Volume Combinations in Patients with Acute Lung Injury Ventilated According to an Open Lung Concept ⬇️

scientific article published on 01 May 2011

Adaptive support ventilation with percutaneous dilatational tracheotomy: a clinical study

scientific article published on 01 September 2008

Adaptive support ventilation with protocolized de-escalation and escalation does not accelerate tracheal extubation of patients after nonfast-track cardiothoracic surgery

scientific article published on 01 September 2010

Adaptive support ventilation: a translational study evaluating the size of delivered tidal volumes.

scientific article published in May 2010

Adaptive support ventilation: an inappropriate mechanical ventilation strategy for acute respiratory distress syndrome?

scientific article published on 01 May 2010

Admission Hyperglycemia in Critically Ill Sepsis Patients: Association With Outcome and Host Response.

scientific article

Adoption of lower tidal volume ventilation improves with feedback and education

scientific article published on 01 December 2007

Age-Dependent Changes in the Pulmonary Renin-Angiotensin System Are Associated With Severity of Lung Injury in a Model of Acute Lung Injury in Rats

scientific article

Age-dependent differences in pulmonary host responses in ARDS: a prospective observational cohort study

article

Alterations in exhaled breath metabolite-mixtures in two rat models of lipopolysaccharide-induced lung injury

scientific article published on 01 August 2013

Alterations in lipoprotein homeostasis during human experimental endotoxemia and clinical sepsis

scientific article published on 12 October 2007

Alveolar but not intravenous S-ketamine inhibits alveolar sodium transport and lung fluid clearance in rats

scientific article published on 2 June 2010

Alveolar fibrinolytic capacity suppressed by injurious mechanical ventilation.

scientific article published on 8 March 2005

Analysis of efficacy and safety of drotrecogin alfa (activated) in surgical patients, using an international integrated database

scientific article published on 01 June 2007

Analyzing effects of providing performance feedback at ward rounds on guideline adherence - the importance of feedback usage analysis and statistical control charts

scientific article published on January 1, 2010

Angiopoietin-1 treatment reduces inflammation but does not prevent ventilator-induced lung injury

scientific article

Anti-C5a antibody IFX-1 (vilobelimab) treatment versus best supportive care for patients with severe COVID-19 (PANAMO): an exploratory, open-label, phase 2 randomised controlled trial

scientific article published on 28 September 2020

Antibiotic-Induced Within-Host Resistance Development of Gram-Negative Bacteria in Patients Receiving Selective Decontamination or Standard Care

scientific article published on 7 October 2015

Antibiotics or probiotics as preventive measures against ventilator-associated pneumonia: a literature review ⬇️

scientific article published on January 13, 2011

Anticoagulant Therapy for Acute Lung Injury or Pneumonia ⬇️

scientific article published on May 1, 2003

Antithrombin inhibits bronchoalveolar activation of coagulation and limits lung injury during Streptococcus pneumoniae pneumonia in rats*

scientific article published on 01 January 2008

Are height and weight estimates in ED patients reliable for setting the ventilator?

scientific article published on 5 June 2017

Are nondepolarizing neuromuscular blocking agents truly a risk factor for late-onset ventilator-associated pneumonia?

scientific article published on 2 June 2005

Assembly 2: respiratory intensive care

scientific article

Assessing Extravascular Lung Water in Critically Ill Patients Using Lung Ultrasound: A Systematic Review on Methodological Aspects in Diagnostic Accuracy Studies

scientific article published on 03 April 2020

Assessment of intensive care unit-acquired weakness in young and old mice: An E. coli septic peritonitis model

scientific article

Assessment of ventilation during the performance of elective endoscopic-guided percutaneous tracheostomy

scientific article published in June 2005

Association between Maturation and Aging and Pulmonary Responses in Animal Models of Lung Injury: A Systematic Review

scientific article published on August 2015

Association between driving pressure and development of postoperative pulmonary complications in patients undergoing mechanical ventilation for general anaesthesia: a meta-analysis of individual patient data.

scientific article

Association between pre-operative biological phenotypes and postoperative pulmonary complications: An unbiased cluster analysis

scientific article published on 01 September 2018

Association between static and dynamic thenar near-infrared spectroscopy and mortality in patients with sepsis: a systematic review and meta-analysis

scientific article published on January 2014

Association between tidal volume size, duration of ventilation, and sedation needs in patients without acute respiratory distress syndrome: an individual patient data meta-analysis.

scientific article

Association between use of lung-protective ventilation with lower tidal volumes and clinical outcomes among patients without acute respiratory distress syndrome: a meta-analysis

scientific article published on 01 October 2012

Association of Gender With Outcome and Host Response in Critically Ill Sepsis Patients

scientific article published on 11 August 2017

Association of diabetes and diabetes treatment with the host response in critically ill sepsis patients

scientific article published on 06 August 2016

Associations between bolus infusion of hydrocortisone, glycemic variability and insulin infusion rate variability in critically Ill patients under moderate glycemic control.

scientific article

Associations between changes in oxygenation, dead space and driving pressure induced by the first prone position session and mortality in patients with acute respiratory distress syndrome

scientific article published on 01 December 2019

Associations between dynamics of the blood glucose level after hypoglycemia and intensive care unit mortality: a retrospective multicenter study

scientific article published on 10 July 2015

Associations between positive end-expiratory pressure and outcome of patients without ARDS at onset of ventilation: a systematic review and meta-analysis of randomized controlled trials.

scientific article

Associations between ventilator settings during extracorporeal membrane oxygenation for refractory hypoxemia and outcome in patients with acute respiratory distress syndrome: a pooled individual patient data analysis : Mechanical ventilation during E

article

Atelectasis during general anaesthesia for surgery: should we treat atelectasis or the patient?

scientific article published on 06 April 2020

Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children

scientific article (published 2014-06-10)

Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children ⬇️

scientific article (published 2013-06-06)

Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children

scientific article

Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children: a cochrane systematic review and meta-analysis

scientific article

Bacterial pneumonia as an influenza complication

scientific article

Bagging--an (early) harmful or (late) beneficial maneuver?

scientific article published on 01 December 2008

Balanced versus isotonic saline resuscitation-a systematic review and meta-analysis of randomized controlled trials in operation rooms and intensive care units.

scientific article published on August 2017

Bench to bedside: targeting coagulation and fibrinolysis in acute lung injury

scientific article published on 28 April 2006

Bench-to-bedside review: Damage-associated molecular patterns in the onset of ventilator-induced lung injury

scientific article

Bench-to-bedside review: bacterial pneumonia with influenza - pathogenesis and clinical implications

scientific article

Bench-to-bedside review: the effects of hyperoxia during critical illness

scientific article (publication date: 2015)

Benefits and risks of manual hyperinflation in intubated and mechanically ventilated intensive care unit patients: a systematic review ⬇️

scientific article published on August 3, 2012

Benefits of early tracheotomy: underpowered or overestimated?

scientific article published on 14 October 2008

Between-trial heterogeneity in ARDS research

publication published on 13 March 2021

Beyond sepsis: activated protein C and ischemia-reperfusion injury

scientific article published on May 2004

Blood transfusion during cardiac surgery is associated with inflammation and coagulation in the lung: a case control study.

scientific article published on 11 February 2011

Body mass index and mortality in patients with acute lung injury

scientific article published on 01 February 2007

Brain computer tomography in critically ill patients--a prospective cohort study.

scientific article published on 12 December 2012

BreathDx - molecular analysis of exhaled breath as a diagnostic test for ventilator-associated pneumonia: protocol for a European multicentre observational study

scientific article

Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis

scientific article

Bronchoalveolar coagulation and fibrinolysis in endotoxemia and pneumonia

scientific article

Bronchoalveolar levels of plasminogen activator inhibitor-1 and soluble tissue factor are sensitive and specific markers of pulmonary inflammation

scientific article published on 14 April 2006

Can we abandon daily routine chest radiography in intensive care patients?

scientific article

Cardiac arrest patients have an impaired immune response, which is not influenced by induced hypothermia

scientific article

Case report: a ball valve blood clot in the airways - life-saving whole tube suction

scientific article

Central venous catheter use in severe malaria: time to reconsider the World Health Organization guidelines?

scientific article published on 14 November 2011

Challenges and Opportunities for Lung Ultrasound in Novel Coronavirus Disease (COVID-19)

scientific article published on 24 April 2020

Changes in Attitudes and Actual Practice of Oxygen Therapy in ICUs after Implementation of a Conservative Oxygenation Guideline

scientific article published on 24 March 2020

Changes in ventilator settings and ventilation-induced lung injury in burn patients-A systematic review

scientific article published on 12 June 2019

Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN): evolution of a content management system for point-of-care clinical decision support.

scientific article

Chest radiography practice in critically ill patients: a postal survey in the Netherlands

scientific article

Choosing the correct metrics for glucose control

scientific article

Chronic antiplatelet therapy is not associated with alterations in the presentation, outcome, or host response biomarkers during sepsis: a propensity-matched analysis.

scientific article published on 14 January 2016

Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study

scientific article published on 29 August 2017

Clinical Characteristics and Outcomes of Patients With Cellulitis Requiring Intensive Care

scientific article published on 15 March 2017

Clinical and hemostatic responses to treatment in ventilator-associated pneumonia: role of bacterial pathogens

scientific article published in February 2007

Clinical practice of respiratory virus diagnostics in critically ill patients with a suspected pneumonia: A prospective observational study.

scientific article published on 16 August 2016

Clinical review: Strict or loose glycemic control in critically ill patients--implementing best available evidence from randomized controlled trials

scientific article published on 07 June 2010

Clinically relevant differences in accuracy of enteral nutrition feeding pump systems

scientific article published on 01 July 2006

Coagulation biomarkers in critically ill patients

scientific article

Coagulopathy as a therapeutic target for TRALI: rationale and possible sites of action

scientific article published on January 2012

Comment on "antibacterial-coated tracheal tubes cleaned with a Mucus Shaver" by Berra et al

scientific article published on 13 October 2006

Comparative Analysis of the Host Response to Community-acquired and Hospital-acquired Pneumonia in Critically Ill Patients

scientific article published on 6 June 2016

Comparison of classification methods in breath analysis by electronic nose.

scientific article published on 15 December 2015

Compartmentalisation of cytokines and cytokine inhibitors in ventilator-associated pneumonia

scientific article published on 21 November 2003

Complications of percutaneous dilating tracheostomy

scientific article

Computer-driven protocolized weaning from mechanical ventilation

scientific article published on 01 May 2007

Continuous glucose monitoring in the ICU: clinical considerations and consensus.

scientific article published on 31 July 2017

Contrast media inhibit exogenous surfactant therapy in rats with acute respiratory distress syndrome

scientific article published in March 2006

Correct conclusions, but doubtful implications

scientific article

Correction of subclinical coagulation disorders before percutaneous dilatational tracheotomy ⬇️

scientific article published on February 13, 2012

Correction to: External confirmation and exploration of the Kigali modification for diagnosing moderate or severe ARDS.

scientific article published on 20 February 2018

Correlation of biomarkers for parasite burden and immune activation with acute kidney injury in severe falciparum malaria

scientific article published on 12 March 2014

Critical Care in Resource-Restricted Settings

scientific article

Critical care outcomes in resource-limited settings

scientific article published on 01 October 2018

Critical illness in developing countries: dying in the dark ⬇️

scientific article published on April 23, 2011

Critically ill patients demonstrate large interpersonal variation in intestinal microbiota dysregulation: a pilot study.

scientific article published on 11 November 2016

Cumulative fluid balance predicts mortality and increases time on mechanical ventilation in ARDS patients: An observational cohort study

scientific article published on 30 October 2019

Current challenges in the management of sepsis in ICUs in resource-poor settings and suggestions for the future

scientific article published on 27 March 2017

Current research priorities in perioperative intensive care medicine.

scientific article published on 08 June 2017

Cyclin-Dependent Kinase Inhibition Reduces Lung Damage in a Mouse Model of Ventilator-Induced Lung Injury ⬇️

scientific article published on 01 October 2012

Cystatin C in critically ill patients treated with continuous venovenous hemofiltration

scientific article published on 01 October 2006

Cytomegalovirus reactivation and mortality in patients with acute respiratory distress syndrome.

scientific article published on 28 September 2015

Cytomegalovirus seroprevalence as a risk factor for poor outcome in acute respiratory distress syndrome*.

scientific article published on February 2015

DETECT the Extremes That Usually Remain Undetected in Conventional Observational Studies

scientific article published on 17 March 2016

Decision making in interhospital transport of critically ill patients: national questionnaire survey among critical care physicians

scientific article published on 19 February 2008

Decisional responsibility for mechanical ventilation and weaning: an international survey ⬇️

scientific article published on December 14, 2011

Decreased alveolar fibrinolysis in patients with ventilator-associated pneumonia: a species-specific event

scientific article published in October 2007

Detection of Invasive Aspergillosis in Critically Ill Patients with Influenza: The Role of Plasma Galactomannan

scientific article published on 01 September 2019

Determinants of tidal volumes with adaptive support ventilation: a multicenter observational study

scientific article published on 01 September 2008

Determinants of transfusion decisions in a mixed medical-surgical intensive care unit: a prospective cohort study

scientific article published on April 2009

Detrimental factors during positive-pressure ventilation: pressure, flow, and/or volume?

scientific article published on 01 June 2007

Developing specific therapeutic strategies for transfusion-related acute lung injury. An overview of potentially useful animal models

scientific article published on October 2007

Development of a model for anemia of inflammation that is relevant to critical care

scientific article published on 25 July 2019

Dexamethasone Attenuates VEGF Expression and Inflammation but Not Barrier Dysfunction in a Murine Model of Ventilator–Induced Lung Injury ⬇️

scientific article published on February 25, 2013

Diabetic status and the relation of the three domains of glycemic control to mortality in critically ill patients: an international multicenter cohort study

scientific article published on March 2013

Diagnostic accuracy of quantitative neuromuscular ultrasound for the diagnosis of intensive care unit-acquired weakness: a cross-sectional observational study

scientific article

Discrepancies between observed and predicted continuous venovenous hemofiltration removal of antimicrobial agents in critically ill patients and the effects on dosing

scientific article published on 17 October 2006

Disseminated intravascular coagulation in infectious disease

scientific article published on June 2010

Do We Need to Pay Toll on the Bridge from Innate Immunity to Ventilator-induced Diaphragm Atrophy? ⬇️

scientific article published on 01 August 2012

Dobutamine to rescue the microcirculation?

scientific article published on 01 October 2006

Draining all pleural effusions in the intensive care unit?

scientific article

ECMO Centers and Mortality From Influenza A(H1N1) ⬇️

scientific article published on 01 February 2012

EEG reactivity testing for prediction of good outcome in patients after cardiac arrest

scientific article published on 10 July 2020

ERS International Congress, Madrid, 2019: highlights from the Respiratory Intensive Care Assembly

scientific article published on 01 January 2020

ERS statement on chest imaging in acute respiratory failure

scientific article published on 19 September 2019

ESA Clinical Trials Network 2012: LAS VEGAS--Local Assessment of Ventilatory Management during General Anaesthesia for Surgery and its effects on Postoperative Pulmonary Complications: a prospective, observational, international, multicentre cohort

scientific article published on 01 May 2013

Early Lessons on the Importance of Lung Imaging in Novel Coronavirus Disease (COVID-19)

scientific article published on 03 April 2020

Early Prediction of Intensive Care Unit-Acquired Weakness: A Multicenter External Validation Study

scientific article published on 01 January 2018

Early intravenous unfractionated heparin and outcome in acute lung injury and acute respiratory distress syndrome – a retrospective propensity matched cohort study ⬇️

scientific article published on August 15, 2012

Early intravenous unfractioned heparin--also beneficial in acute lung injury?

scientific article published on 01 April 2009

Early or late tracheostomy

scientific article published in February 2005

Early prediction of intensive care unit-acquired weakness using easily available parameters: a prospective observational study

scientific article

Early procoagulant shift in the bronchoalveolar compartment of patients with secondary peritonitis

scientific article published on 22 September 2006

Early versus delayed initiation of renal replacement therapy for acute kidney injury: an updated systematic review, meta-analysis, meta-regression and trial sequential analysis of randomized controlled trials

article

Effect of Intraoperative High Positive End-Expiratory Pressure (PEEP) With Recruitment Maneuvers vs Low PEEP on Postoperative Pulmonary Complications in Obese Patients: A Randomized Clinical Trial

scientific article published on 01 June 2019

Effect of On-Demand vs Routine Nebulization of Acetylcysteine With Salbutamol on Ventilator-Free Days in Intensive Care Unit Patients Receiving Invasive Ventilation: A Randomized Clinical Trial

scientific article published on 01 March 2018

Effect of a Low vs Intermediate Tidal Volume Strategy on Ventilator-Free Days in Intensive Care Unit Patients Without ARDS: A Randomized Clinical Trial

scientific article published in The Journal of the American Medical Association

Effect of a clinical decision support system on adherence to a lower tidal volume mechanical ventilation strategy

scientific article published on 20 February 2009

Effect of cytomegalovirus reactivation on the time course of systemic host response biomarkers in previously immunocompetent critically ill patients with sepsis: a matched cohort study

Effect of extracorporeal CO2 removal on right ventricular and hemodynamic parameters in a patient with acute respiratory distress syndrome

scientific article published on 6 December 2015

Effectiveness and Clinical Outcomes of a Two-Step Implementation of Conservative Oxygenation Targets in Critically Ill Patients: A Before and After Trial.

scientific article published on 11 November 2015

Effects of Protective Mechanical Ventilation With Different PEEP Levels on Alveolar Damage and Inflammation in a Model of Open Abdominal Surgery: A Randomized Study in Obese Versus Non-obese Rats

scientific article published on 17 December 2019

Effects of Volatile Anesthetics on Mortality and Postoperative Pulmonary and Other Complications in Patients Undergoing Surgery: A Systematic Review and Meta-analysis.

scientific article published on 11 April 2016

Effects of peep on lung injury, pulmonary function, systemic circulation and mortality in animals with uninjured lungs-a systematic review

scientific article published in January 2018

Effects of selective decontamination of digestive tract on mortality and acquisition of resistant bacteria in intensive care: a randomised controlled trial ⬇️

scientific article published on September 27, 2003

Effects of two different levels of computerized decision support on blood glucose regulation in critically ill patients

scientific article published on 8 November 2011

Electrical impedance tomography--a new toy for boys or the future for mechanically ventilated patients?

scientific article published on 01 April 2008

Electroencephalographic reactivity as predictor of neurological outcome in postanoxic coma: A multicenter prospective cohort study

scientific article published on 08 June 2019

Electronic implementation of a novel surveillance paradigm for ventilator-associated events. Feasibility and validation.

scientific article published on April 2014

Elimination of daily routine chest radiographs does not change on-demand radiography practice in post-cardiothoracic surgery patients

scientific article published on 01 July 2007

Elimination of daily routine chest radiographs in a mixed medical-surgical intensive care unit

scientific article

Endogenous tissue factor pathway inhibitor has a limited effect on host defence in murine pneumococcal pneumonia.

scientific article published on 2 April 2015

Epidemiological characteristics, practice of ventilation, and clinical outcome in patients at risk of acute respiratory distress syndrome in intensive care units from 16 countries (PRoVENT): an international, multicentre, prospective study

scientific article published on 4 October 2016

Epidemiology and outcomes of source control procedures in critically ill patients with intra-abdominal infection

scientific article published on 01 May 2019

Epidemiology of Multiple Herpes Viremia in Previously Immunocompetent Patients With Septic Shock

scientific article published on 4 February 2017

Erratum to: Recommendations for sepsis management in resource-limited settings

scholarly article published in Intensive Care Medicine

Estimated dead space fraction and the ventilatory ratio are associated with mortality in early ARDS

scientific article published on 21 November 2019

European Respiratory Society International Congress 2018: highlights from Assembly 2 on respiratory intensive care

article

Evaluating tele-ICU reengineering of critical care processes

scientific article published on 01 October 2011

Evaluation of consulting and critiquing decision support systems: effect on adherence to a lower tidal volume mechanical ventilation strategy

scientific article published on 14 December 2011

Evidence--lost to tight glycemic control?

scientific article published on 20 October 2008

Evidence-based nutrition guidelines for critically ill adults

scientific article published on 01 April 2009

Evolution of ventilator settings during general anaesthesia for neurosurgery: An observational study in a German centre over 15 years

scientific article

Exhaled Breath Metabolomics for the Diagnosis of Pneumonia in Intubated and Mechanically-Ventilated Intensive Care Unit (ICU)-Patients.

scientific article published on 19 February 2017

Exhaled breath metabolomics as a noninvasive diagnostic tool for acute respiratory distress syndrome

scientific article published on 17 April 2014

Exhaled breath metabolomics reveals a pathogen-specific response in a rat pneumonia model for two human pathogenic bacteria: a proof-of-concept study

scientific article published on 13 February 2019

Exhaled breath profiling for diagnosing acute respiratory distress syndrome ⬇️

scientific article

External confirmation and exploration of the Kigali modification for diagnosing moderate or severe ARDS.

scientific article published on 24 January 2018

External validation confirms the legitimacy of a new clinical classification of ARDS for predicting outcome

scientific article published on 23 July 2015

External validation of the APPS, a new and simple outcome prediction score in patients with the acute respiratory distress syndrome.

scientific article published on 15 September 2016

Extracellular histone H3 levels are inversely correlated with antithrombin levels and platelet counts and are associated with mortality in sepsis patients

scientific article published on 23 July 2015

Extracorporeal life support. A "breath-taking" technology?

scientific article published in June 2014

Factors Influencing Continuous Breath Signal in Intubated and Mechanically-Ventilated Intensive Care Unit Patients Measured by an Electronic Nose.

scientific article published on 22 August 2016

Feasibility and Safety of Local Treatment with Recombinant Human Tissue Factor Pathway Inhibitor in a Rat Model of Streptococcus pneumoniae Pneumonia

scientific article published on 18 May 2015

Feasibility and diagnostic accuracy of early electrophysiological recordings for ICU-acquired weakness: an observational cohort study

scientific article published on 01 June 2015

Feedback and education improve physician compliance in use of lung-protective mechanical ventilation

scientific article

Fluid resuscitation with hydroxyethyl starches in patients with sepsis is associated with an increased incidence of acute kidney injury and use of renal replacement therapy: a systematic review and meta-analysis of the literature

scientific article

From "inconvenient truth" to "assault on reason".

scientific article published in April 2008

From protective ventilation to super-protective ventilation for acute respiratory distress syndrome ⬇️

scientific article published on January 10, 2013

From the dark side of ventilation toward a brighter look at lungs

scientific article published in May 2013

Gene expression profiling of apoptosis regulators in patients with sepsis

scientific article published on 23 June 2010

Glucontrol, no control, or out of control?

scientific article published on 24 September 2009

Glucose levels of critically ill patients to calculate the hyperglycemic index

scientific article published on 01 August 2006

Glucose prediction by analysis of exhaled metabolites - a systematic review

scientific article

Glucose variability measures and their effect on mortality: a systematic review

scientific article published on 29 January 2011

Glycemic variability is complex--is glucose complexity variable?

scientific article published on 21 November 2012

Glycine does not add to the beneficial effects of perioperative oral immune-enhancing nutrition supplements in high-risk cardiac surgery patients

scientific article published on 01 May 2007

HEPBURN - investigating the efficacy and safety of nebulized heparin versus placebo in burn patients with inhalation trauma: study protocol for a multi-center randomized controlled trial.

scientific article published on 25 March 2014

HETRASE study--did heparin treatment benefit patients with ALI/ARDS?

scientific article published on 01 August 2009

Haemodynamic assessment and support in sepsis and septic shock in resource-limited settings

scientific article published on 9 February 2018

Health Economic Evaluation of a Strict Glucose Control Guideline Implemented Using Point-of-Care Testing in Three Intensive Care Units in The Netherlands

scientific article published on August 2015

Hematologic Failure ⬇️

scientific article published on October 11, 2011

Hemofiltration in sepsis and systemic inflammatory response syndrome: the role of dosing and timing

scientific article published on 31 January 2007

High Levels of S100A8/A9 Proteins Aggravate Ventilator-Induced Lung Injury via TLR4 Signaling ⬇️

scientific article published on July 18, 2013

High versus low PEEP in non-recruitable collapsed lung tissue: possible implications for patients with COVID-19

scientific article published on 20 April 2020

High versus low positive end-expiratory pressure during general anaesthesia for open abdominal surgery (PROVHILO trial): a multicentre randomised controlled trial.

scientific article published on 2 June 2014

How integration of global omics-data could help preparing for pandemics - a scent of influenza.

scientific article

How to detect tidal recruitment and/or alveolar hyperinflation--computed tomography, electrical impedance tomography, or stress index?

scientific article published in March 2008

How to improve quality of research in intensive care medicine

scientific article published in January 2018

How to optimize critical care resources in surgical patients: intensive care without physical borders

scientific article published on 01 December 2018

How to ventilate patients without acute respiratory distress syndrome?

scientific article

Hydrogen sulfide donor NaHS reduces organ injury in a rat model of pneumococcal pneumosepsis, associated with improved bio-energetic status

scientific article

Hydrogen sulfide: a hot molecule

scientific article published on 01 November 2011

Hyperoxia provokes a time- and dose-dependent inflammatory response in mechanically ventilated mice, irrespective of tidal volumes

scientific article published on 26 May 2017

Immunomodulation by macrolides: therapeutic potential for critical care

scientific article published on 01 June 2020

Impact of Different Ventilation Strategies on Driving Pressure, Mechanical Power, and Biological Markers During Open Abdominal Surgery in Rats

scientific article published on 27 July 2017

Impact of HIV infection on the presentation, outcome and host response in patients admitted to the intensive care unit with sepsis; a case control study

scientific article published on 10 October 2016

Impact of ICU-acquired weakness on post-ICU physical functioning: a follow-up study

scientific article published on 27 April 2015

Impact of Positive End-Expiratory Pressure on Thermodilution-Derived Right Ventricular Parameters in Mechanically Ventilated Critically Ill Patients

scientific article published on 25 September 2015

Impact of a structured ICU training programme in resource-limited settings in Asia

scientific article

Implementing glucose control in intensive care: a multicenter trial using statistical process control

scientific article

Improving ICU services in resource-limited settings: Perceptions of ICU workers from low-middle-, and high-income countries

scientific article published on 14 December 2017

In the critically ill patient, diabetes predicts mortality independent of statin therapy but is not associated with acute lung injury: a cohort study

scientific article

Incidence and Mortality of Acute Respiratory Distress Syndrome in Children: A Systematic Review and Meta-Analysis

scientific article

Incidence of mortality and morbidity related to postoperative lung injury in patients who have undergone abdominal or thoracic surgery: a systematic review and meta-analysis.

scientific article

Incidence, Predictors, and Outcomes of New-Onset Atrial Fibrillation in Critically Ill Patients with Sepsis. A Cohort Study.

scientific article

Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in the Intensive Care Unit After Admission for Sepsis

scientific article published on 15 March 2016

Incorporation of Daily Goals in Daily Care Planning Does Not Shorten Length of Stay in the Intensive Care Unit

scientific article published on 01 April 2018

Increased Early Systemic Inflammation in ICU-Acquired Weakness; A Prospective Observational Cohort Study

scientific article published on 27 March 2017

Increased incidence of co-infection in critically ill patients with influenza

scientific article published on 5 October 2016

Increased mortality in elderly patients with acute respiratory distress syndrome is not explained by host response

scientific article published on 29 October 2019

Individual and joint expert judgments as reference standards in artifact detection

scientific article published on 20 December 2007

Induced hypothermia is protective in a rat model of pneumococcal pneumonia associated with increased adenosine triphosphate availability and turnover*.

scientific article published in March 2012

Induced normothermia ameliorates the procoagulant host response in human endotoxaemia

scientific article published on 23 April 2021

Infection and Inflammation as Risk Factors for Thrombosis and Atherosclerosis ⬇️

scientific article published on 07 March 2012

Influence of severity of illness, medication and selective decontamination on defecation

scientific article

Influenza and other respiratory viruses are underdiagnosed in critically ill patients

scientific article

Intensive care unit patients with lower respiratory tract nosocomial infections: the ENIRRIs project.

scientific article published in October 2017

Intensive insulin therapy in intensive care: an example of the struggle to implement evidence-based medicine

scientific article published in December 2006

Interaction between peri-operative blood transfusion, tidal volume, airway pressure and postoperative ARDS: an individual patient data meta-analysis

scientific article published in January 2018

Interference by new-generation mobile phones on critical care medical equipment.

scientific article

International Surviving Sepsis Campaign guidelines 2016: the perspective from low-income and middle-income countries

scientific article published on September 2017

International multicenter observational study on assessment of ventilatory management during general anaesthesia for robotic surgery and its effects on postoperative pulmonary complication (AVATaR): study protocol and statistical analysis plan

scientific article published on 23 August 2018

Interobserver Agreement of Centers for Disease Control and Prevention Criteria for Classifying Infections in Critically Ill Patients* ⬇️

scientific article published on October 1, 2013

Intraabdominal Pressure Targeted Positive End-expiratory Pressure during Laparoscopic Surgery: An Open-label, Nonrandomized, Crossover, Clinical Trial

scientific article published on 01 April 2020

Intraoperative Ventilation Strategies to Reduce Pulmonary Complications in Obese Patients-Reply

scientific article published on 01 November 2019

Intraoperative immunomodulatory effects of sevoflurane versus total intravenous anesthesia with propofol in bariatric surgery (the OBESITA trial): study protocol for a randomized controlled pilot trial.

scientific article published on 28 May 2019

Intraoperative protective mechanical ventilation for prevention of postoperative pulmonary complications: a comprehensive review of the role of tidal volume, positive end-expiratory pressure, and lung recruitment maneuvers

scientific article published on 29 June 2015

Intraoperative ventilation strategies to prevent postoperative pulmonary complications: Systematic review, meta-analysis, and trial sequential analysis

scientific article

Intraoperative ventilator settings and their association with postoperative pulmonary complications in neurosurgical patients: post-hoc analysis of LAS VEGAS study

scientific article published on 02 April 2020

Intraoperative ventilatory strategies to prevent postoperative pulmonary complications: a meta-analysis

scientific article published on April 2013

Intratidal Analysis of Intraoperative Respiratory System Mechanics: Keep it Simple.

scientific article published in February 2018

Investigating associations between ICU level and quality of care in the Netherlands: reporting only SMRs is not the whole story

scientific article published on 12 June 2015

Iron metabolism in critically ill patients developing anemia of inflammation: a case control study.

scientific article published on 2 May 2018

Is Critical Illness Neuromyopathy and Duration of Mechanical Ventilation Decreased by Strict Glucose Control? ⬇️

scientific article published on June 1, 2011

Is gender inequity in ventilator management a "women's issue"?

scientific article published on 17 October 2019

Is gentamicin affecting the neuromuscular system of critically ill patients?

scientific article published on 10 March 2015

Is mechanical power the final word on ventilator-induced lung injury?-no

scholarly article by Robert Huhle et al published October 2018 in Annals of translational medicine

Is surfactant a promising additive drug in ALI/ARDS-patients?

scientific article published in July 2004

Kinase activity is impaired in neutrophils of sepsis patients

scientific article published on 04 December 2018

Kinetics of plasma biomarkers of inflammation and lung injury in surgical patients with or without postoperative pulmonary complications.

scientific article published on 9 February 2017

Known and unknown potentially modifiable factors contributing to outcome in brain-injured patients who need mechanical ventilatory support. Discussion on 'The BI-VILI project: a nationwide quality improvement project'.

scientific article published on 2 May 2017

Laboratory prediction of the requirement for renal replacement in acute falciparum malaria

scientific article

Legislation on research involving patients who are (temporarily) unable to give informed consent: differences between European countries

scientific article published on 8 August 2007

Levels of cytokines in broncho-alveolar lavage fluid, but not in plasma, are associated with levels of markers of lipid peroxidation in breath of ventilated ICU patients.

scientific article published on 03 September 2015

Likelihood of infection in patients with presumed sepsis at the time of intensive care unit admission: a cohort study

scientific article

Limitations and practicalities of CAM-ICU implementation, a delirium scoring system, in a Dutch intensive care unit

scientific article published on 21 June 2009

Low tidal volume ventilation ameliorates left ventricular dysfunction in mechanically ventilated rats following LPS-induced lung injury

scientific article

Low value of routine chest radiographs in a mixed medical-surgical ICU.

scientific article published on September 2007

Lower tidal volumes in Brazil, also in patients without acute respiratory distress syndrome?

scientific article published on 12 June 2013

Lung Microbiota Predict Clinical Outcomes in Critically Ill Patients

scientific article published on 01 March 2020

Lung epithelial injury markers are not influenced by use of lower tidal volumes during elective surgery in patients without preexisting lung injury

scientific article published on 14 December 2007

Lung ultrasound and neonatal ARDS: is Montreux closer to Berlin than to Kigali?

scientific article

Lung-Protective Ventilation With Low Tidal Volumes and the Occurrence of Pulmonary Complications in Patients Without Acute Respiratory Distress Syndrome: A Systematic Review and Individual Patient Data Analysis

scientific article

Lung-protective mechanical ventilation does not protect against acute kidney injury in patients without lung injury at onset of mechanical ventilation ⬇️

scientific article published on June 28, 2011

Lung-protective mechanical ventilation with lower tidal volumes in patients not suffering from acute lung injury: a review of clinical studies.

scientific article published on February 2008

Macrolide therapy is associated with reduced mortality in acute respiratory distress syndrome (ARDS) patients

scientific article published in January 2018

Magnetic Resonance Imaging for Quantitative Assessment of Lung Aeration: A Pilot Translational Study

scientific article published on 13 August 2018

Maldistribution of interalveolar perfusion--one early step in the pathogenesis of lung injury?

scientific article published in February 2008

Management of tracheostomy: a survey of Dutch intensive care units

scientific article published in December 2008

Mandatory checklists at discharge may have the potential to prevent readmissions

scientific article published on 01 April 2010

Manipulation of the microbiome in critical illness-probiotics as a preventive measure against ventilator-associated pneumonia

scientific article published on 25 July 2019

Manual hyperinflation of intubated and mechanically ventilated patients in Dutch intensive care units--a survey into current practice and knowledge

scientific article published on 27 May 2009

Manual hyperinflation partly prevents reductions of functional residual capacity in cardiac surgical patients - a randomized controlled trial ⬇️

scientific article published on August 5, 2011

Manual hyperinflation: Positive end-expiratory pressure to recruit or rapid release for clearance of airway secretions? ⬇️

scientific article published on 01 May 2011

Matrix metalloproteinase-8: a useful biomarker to refine the diagnosis of community-acquired pneumonia upon intensive care unit admission?

scientific article published on 20 June 2019

May frequency of blood glucose measurement be blurring the association between mean absolute glucose change per hour and mortality?

scientific article published on 01 January 2011

Measuring metabolomics in acute lung injury: choosing the correct compartment?

scientific article published on 01 April 2012

Mechanical Ventilation Management during Extracorporeal Membrane Oxygenation for Acute Respiratory Distress Syndrome. An International Multicenter Prospective Cohort

scientific article published on 01 October 2019

Mechanical power of ventilation is associated with mortality in critically ill patients: an analysis of patients in two observational cohorts

scientific article published on 05 October 2018

Mechanical ventilation in critically ill patients with 2009 influenza A(H1N1)

scientific article published on 01 March 2010

Mechanical ventilation in neurocritical care patients: a systematic literature review

scientific article published on 16 September 2016

Mechanical ventilation of the healthy lungs: lessons learned from recent trials

scientific article published on 10 December 2020

Mechanical ventilation strategies for the surgical patient

scientific article published on August 2015

Mechanical ventilation using non-injurious ventilation settings causes lung injury in the absence of pre-existing lung injury in healthy mice

scientific article published on 19 January 2009

Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents alveolar coagulation in patients without lung injury

scientific article published in October 2006

Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents pulmonary inflammation in patients without preexisting lung injury

scientific article published in January 2008

Mechanical ventilation with lower tidal volumes does not influence the prescription of opioids or sedatives

scientific article

Medical-grade honey does not reduce skin colonization at central venous catheter-insertion sites of critically ill patients: a randomized controlled trial ⬇️

scientific article published on October 30, 2012

Medical-grade honey kills antibiotic-resistant bacteria in vitro and eradicates skin colonization

scientific article published in June 2008

Metrics of Arterial Hyperoxia and Associated Outcomes in Critical Care

scientific article published on 19 October 2016

Microbiological profile of nosocomial infections following cardiac arrest: Insights from the targeted temperature management (TTM) trial

scientific article published on 04 February 2020

Microparticles: Still Far From Being the Ideal Biomarker for Ventilator-Associated Lung Injury

scientific article published on 01 December 2015

Mild hypoglycemia is independently associated with increased mortality in the critically ill.

scientific article

Mild hypoglycemia is strongly associated with increased intensive care unit length of stay ⬇️

scientific article published on November 24, 2011

Mild hypothermia reduces ventilator-induced lung injury, irrespective of reducing respiratory rate

scientific article published on 10 November 2011

Mixing up old data

scientific article

Modeling intra-abdominal volume and respiratory driving pressure during pneumoperitoneum insufflation - a patient-level data meta-analysis

scientific article published on 24 December 2020

Modulation of innate immune responses in the treatment of sepsis and pneumonia

scientific article published on March 2004

Modulation of pulmonary innate immunity during bacterial infection: animal studies

scientific article

Molecular Biomarker to Assist in Diagnosing Abdominal Sepsis upon ICU Admission

scientific article published on 01 April 2018

Muscle and nerve inflammation in intensive care unit-acquired weakness: a systematic translational review

scientific article

Muscle weakness in a S. pneumoniae sepsis mouse model

scientific article published on 01 January 2019

Myeloid-related protein-8/14 facilitates bacterial growth during pneumococcal pneumonia

scientific article published on September 2014

Myocardial Function during Low versus Intermediate Tidal Volume Ventilation in Patients without Acute Respiratory Distress Syndrome

scientific article published on 11 February 2020

Myocardial Function during Ventilation with Lower versus Higher Positive End-Expiratory Pressure in Patients without ARDS

scientific article published on 21 April 2022

Nebulized C1-Esterase Inhibitor does not Reduce Pulmonary Complement Activation in Rats with Severe Streptococcus Pneumoniae Pneumonia.

scientific article published on 28 September 2016

Nebulized Heparin in Burn Patients with Inhalation Trauma-Safety and Feasibility

scientific article published on 25 March 2020

Nebulized Recombinant Human Tissue Factor Pathway Inhibitor Attenuates Coagulation and Exerts Modest Anti-inflammatory Effects in Rat Models of Lung Injury

scientific article published on 15 December 2016

Nebulized anticoagulants for acute lung injury - a systematic review of preclinical and clinical investigations

scientific article published on 12 December 2012

Nebulized anticoagulants in lung injury in critically ill patients-an updated systematic review of preclinical and clinical studies

scientific article published in November 2017

Nebulized anticoagulants limit coagulopathy but not inflammation in pseudomonas aeruginosa-induced pneumonia in rats

scientific article published on 01 October 2011

Nebulized anticoagulants limit pulmonary coagulopathy, but not inflammation, in a model of experimental lung injury

scientific article published on 01 April 2010

Nebulized antithrombin limits bacterial outgrowth and lung injury in Streptococcus pneumoniae pneumonia in rats

scientific article published on 9 September 2009

Nebulized fibrinolytic agents improve pulmonary fibrinolysis but not inflammation in rat models of direct and indirect acute lung injury

scientific article

Nebulized heparin for patients under mechanical ventilation: an individual patient data meta-analysis

scientific article

Nebulized heparin is associated with fewer days of mechanical ventilation in critically ill patients: a randomized controlled trial ⬇️

scientific article published on October 11, 2010

Nebulized heparin reduces levels of pulmonary coagulation activation in acute lung injury ⬇️

scientific article published on October 20, 2010

Need for critical appraisal of implementation of use of lower tidal volumes

scientific article published in November 2005

Neurally adjusted ventilatory assist decreases ventilator-induced lung injury and non-pulmonary organ dysfunction in rabbits with acute lung injury

scientific article published in November 2009

Neurofilaments as a plasma biomarker for ICU-acquired weakness: an observational pilot study

scientific article

Neuromuscular blocking agents and postoperative pulmonary complications

scientific article published on 14 September 2018

Neuromuscular blocking agents in patients with acute respiratory distress syndrome: a summary of the current evidence from three randomized controlled trials

scientific article published on 26 July 2012

New Surviving Sepsis Campaign guidelines: back to the art of medicine

scientific article published on 11 July 2018

Nlrp3 plays no role in acute cardiac infarction due to low cardiac expression

scientific article published on 10 October 2014

No association between systemic complement activation and intensive care unit-acquired weakness.

scientific article

Non-invasive breath monitoring with eNose does not improve glucose diagnostics in critically ill patients in comparison to continuous glucose monitoring in blood.

scientific article published on 6 March 2017

Normalization of mechanical power to anthropometric indices: impact on its association with mortality in critically ill patients

scientific article published on 08 October 2019

Notice of Retraction and Replacement: Oostdijk et al. Effects of Decontamination of the Oropharynx and Intestinal Tract on Antibiotic Resistance in ICUs: A Randomized Clinical Trial. JAMA. 2014;312(14):1429-1437.

scientific article published on April 2017

Nurses versus physician-led interhospital critical care transport: a randomized non-inferiority trial

scientific article published on 11 May 2016

Of hypes and hopes: N-acetylcysteine and cystatin C.

scientific article

On-demand rather than daily-routine chest radiography prescription may change neither the number nor the impact of chest computed tomography and ultrasound studies in a multidisciplinary intensive care unit

scientific article published in January 2008

Open-lung Ventilation Strategy during General Anesthesia

scientific article published on 24 September 2020

Opinions and Management of Hypothermic Sepsis: Results from an Online Survey

scientific article published on 24 June 2019

Optimizing perioperative mechanical ventilation as a key quality improvement target

scientific article published on April 2015

Optimizing respiratory management in resource-limited settings

Optimizing the Settings on the Ventilator: High PEEP for All?

scientific article published on 21 March 2017

Outcomes of Patients Presenting with Mild Acute Respiratory Distress Syndrome

scientific article published on 01 February 2019

Overweight in ICU patients: is the body mass index reliable?

scientific article published on 01 February 2005

PCT and sTREM-1: the markers of infection in critically ill patients?

scientific article published on December 2008

PReVENT--protective ventilation in patients without ARDS at start of ventilation: study protocol for a randomized controlled trial

scientific article published on 24 May 2015

Patients with uninjured lungs may also benefit from lung-protective ventilator settings

scientific article published on 22 November 2017

Percutaneous tracheostomies are preferable to surgical tracheostomies

scientific article published on 01 February 2007

Performance of manual hyperinflation: a skills lab study among trained intensive care unit nurses.

scientific article published in August 2009

Perioperative Lung Protection: Clinical Implications

scientific article published on 01 December 2020

Pharmacokinetics and pharmacodynamics of danaparoid during continuous venovenous hemofiltration: a pilot study

scientific article

Plasma CC16 levels are associated with development of ALI/ARDS in patients with ventilator-associated pneumonia: a retrospective observational study

scientific article

Plasma fractalkine is a sustained marker of disease severity and outcome in sepsis patients.

scientific article

Plasma levels of surfactant protein D and KL-6 for evaluation of lung injury in critically ill mechanically ventilated patients

scientific article

Plasma sRAGE is independently associated with increased mortality in ARDS: a meta-analysis of individual patient data

article

Plasma suPAR as a prognostic biological marker for ICU mortality in ARDS patients

scientific article published on 23 June 2015

Plasminogen activator inhibitor-type I gene deficient mice show reduced influx of neutrophils in ventilator-induced lung injury

scientific article

Platelet Toll-like receptor expression and activation induced by lipopolysaccharide and sepsis

scientific article published on 12 March 2018

Pneumonia models and innate immunity to respiratory bacterial pathogens

scientific article

Point accuracy and reliability of an interstitial continuous glucose-monitoring device in critically ill patients: a prospective study

scientific article

Point of care ultrasound for sepsis management in resource-limited settings: response to Via et al

Point-of-care lung ultrasound for the detection of pulmonary manifestations of malaria and sepsis: An observational study

scientific article published in PLoS ONE

Positive blood cultures or Gram-negative pathogens with ventilator-associated pneumonia: What's the real killer?

scientific article published on 01 September 2007

Positive end-expiratory pressure during surgery - Authors' reply

scientific article published on 7 November 2014

Post-anaesthesia pulmonary complications after use of muscle relaxants (POPULAR): a multicentre, prospective observational study

scientific article published on 14 September 2018

Postoperative pneumonia or ventilator-induced lung injury?

scientific article published on 20 December 2014

Potential Diagnostic Properties of Chest Ultrasound in Thoracic Tuberculosis-A Systematic Review

scientific article published on 12 October 2018

Potential applications of hydrogen sulfide-induced suspended animation

scientific article published on January 2009

Potential of Parameters of Iron Metabolism for the Diagnosis of Anemia of Inflammation in the Critically Ill

scientific article published on 03 May 2019

Potentially modifiable respiratory variables contributing to outcome in ICU patients without ARDS: a secondary analysis of PRoVENT.

scientific article

Practice of mechanical ventilation in cardiac arrest patients and effects of targeted temperature management: A substudy of the targeted temperature management trial

scientific article published on 12 May 2018

Practice of strict glycemic control in critically ill patients

scientific article

Pre-treatment with allopurinol or uricase attenuates barrier dysfunction but not inflammation during murine ventilator-induced lung injury ⬇️

scientific article published on November 30, 2012

Predicting Fluid Responsiveness by Passive Leg Raising: A Systematic Review and Meta-Analysis of 23 Clinical Trials

scientific article

Prediction of extubation failure in Intensive Care Unit: systematic review of parameters investigated

scientific article published on 09 July 2018

Prediction of postoperative pulmonary complications

scientific article published on 01 June 2019

Predictive value of plasma biomarkers for mortality and organ failure development in patients with acute respiratory distress syndrome

scientific article published on 6 September 2014

Prescription of rh-APC differs substantially among western European countries

scientific article published on 07 March 2006

Preventing TRALI: ladies first, what follows?

scientific article published on 01 December 2008

Preventing mucus plugging in invasively ventilated intensive care unit patients-routine or personalized care and 'primum non nocere'

scientific article published on 01 December 2018

Prevention of VAP: "WHAP" should we do?

scientific article published on 01 February 2010

Preventive nebulization of mucolytic agents and bronchodilating drugs in invasively ventilated intensive care unit patients (NEBULAE): study protocol for a randomized controlled trial

scientific article

Prior Use of Calcium Channel Blockers Is Associated With Decreased Mortality in Critically Ill Patients With Sepsis: A Prospective Observational Study.

scientific article published on 10 January 2017

Procoagulant and fibrinolytic activity in cerebrospinal fluid from adults with bacterial meningitis

scientific article published on 4 January 2007

Promising but still uncertain steps towards better prediction of functional outcome in ICU patients

scientific article published on August 2016

Protease-Activated Receptor 2 Facilitates Bacterial Dissemination in Pneumococcal Pneumonia

scientific article published on 5 February 2018

Protective mechanical ventilation during general anesthesia for open abdominal surgery improves postoperative pulmonary function

scientific article published on June 2013

Protective ventilation for patients without acute respiratory distress syndrome--reply

scientific article published in February 2013

Protective versus Conventional Ventilation for Surgery: A Systematic Review and Individual Patient Data Meta-analysis.

scientific article

Protocol for a systematic review and individual patient data meta-analysis of benefit of so-called lung-protective ventilation settings in patients under general anesthesia for surgery

scientific article

Pulmonary activation of coagulation and inhibition of fibrinolysis after burn injuries and inhalation trauma

scientific article published on 01 June 2011

Pulmonary coagulopathy as a new target in lung injury--a review of available pre-clinical models

scientific article published on January 2008

Pulmonary coagulopathy as a new target in therapeutic studies of acute lung injury or pneumonia--a review

scientific article

Pulmonary coagulopathy: a potential therapeutic target in different forms of lung injury

scientific article published on July 2007

Pulmonary complement depositions in autopsy of critically ill patients have no relation with ARDS

scientific article published on 25 July 2019

Pulmonary complications after cardiac surgery: ventilator associated lung injury?

scientific article published in March 2007

Pulmonary levels of biomarkers for inflammation and lung injury in protective versus conventional one-lung ventilation for oesophagectomy: A randomised clinical trial

scientific article published on 04 December 2019

Pulmonary levels of high-mobility group box 1 during mechanical ventilation and ventilator-associated pneumonia

scientific article published on 01 April 2008

Pulse pressure variation does not reflect stroke volume variation in mechanically ventilated rats with lipopolysaccharide-induced pneumonia

scientific article published in January 2014

RELAx - REstricted versus Liberal positive end-expiratory pressure in patients without ARDS: protocol for a randomized controlled trial.

scientific article published on 9 May 2018

RETRACTED: Effects of decontamination of the oropharynx and intestinal tract on antibiotic resistance in ICUs: a randomized clinical trial

retracted scientific article published on October 2014

Rationale and study design of PROVHILO - a worldwide multicenter randomized controlled trial on protective ventilation during general anesthesia for open abdominal surgery ⬇️

scientific article

Recent advances in mechanical ventilation in patients without acute respiratory distress syndrome

scientific article

Recombinant human activated protein C in the treatment of acute respiratory distress syndrome: a randomized clinical trial.

scientific article

Recombinant human activated protein C inhibits local and systemic activation of coagulation without influencing inflammation during Pseudomonas aeruginosa pneumonia in rats

scientific article published on 01 May 2007

Recombinant human soluble tumor necrosis factor-alpha receptor fusion protein partly attenuates ventilator-induced lung injury

scientific article published on 01 March 2009

Recommendations for sepsis management in resource-limited settings

scientific article

Recommendations on infrastructure and organization of adult ICUs in resource-limited settings.

scientific article published on 20 November 2017

Reduced Cardiac Index Reserve and Hypovolemia in Severe Falciparum Malaria

scientific article published on 01 April 2020

Reduced Responsiveness of Blood Leukocytes to Lipopolysaccharide Does not Predict Nosocomial Infections in Critically Ill Patients

scientific article

Relative Tissue Factor Deficiency Attenuates Ventilator-Induced Coagulopathy but Does Not Protect against Ventilator-Induced Lung Injury in Mice.

scientific article

Reliability of height and weight estimates in patients acutely admitted to intensive care units.

scientific article published in October 2007

Reply to: high versus low positive end-expiratory pressure for abdominal surgery

scientific article published on 01 January 2018

Resolved versus confirmed ARDS after 24 h: insights from the LUNG SAFE study

scientific article published on 9 April 2018

Respiratory Support in Novel Coronavirus Disease (COVID-19) Patients, with a Focus on Resource-Limited Settings

scientific article published on 21 April 2020

Respiratory System Mechanics During Low Versus High Positive End-Expiratory Pressure in Open Abdominal Surgery: A Substudy of PROVHILO Randomized Controlled Trial.

scientific article published on 19 June 2017

Respiratory Viruses in Invasively Ventilated Critically Ill Patients-A Prospective Multicenter Observational Study

scientific article published on 6 October 2017

Respiratory support in patients with acute respiratory distress syndrome: an expert opinion

scientific article published on 12 September 2017

Review of a large clinical series: the value of routinely obtained chest radiographs on admission to a mixed medical--surgical intensive care unit

scientific article published on 18 May 2010

Risk factors and outcome of transfusion-related acute lung injury in the critically ill: a nested case-control study

scientific article

Risk factors, host response and outcome of hypothermic sepsis.

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Risk stratification using SpO2/FiO2 and PEEP at initial ARDS diagnosis and after 24 h in patients with moderate or severe ARDS.

scientific article published on 25 October 2017

Role of shear stress in ventilator-induced lung injury - Authors' reply

scientific article published on 20 June 2016

SEPsis REcognition and MAnagement (SEPREMA survey).

scientific article published on 11 January 2016

Selective decontamination of the digestive tract halves the prevalence of ventilator-associated pneumonia compared to selective oral decontamination.

scientific article published on 11 May 2017

Selective decontamination of the digestive tract reduces mortality in critically ill patients ⬇️

scientific article published on January 24, 2003

Self-reported attitudes versus actual practice of oxygen therapy by ICU physicians and nurses

scientific article

Sepsis Patients Display a Reduced Capacity to Activate Nuclear Factor-κB in Multiple Cell Types

scientific article published on 24 February 2017

Sepsis and Thrombosis ⬇️

scientific article published on April 27, 2013

Serial changes in soluble triggering receptor expressed on myeloid cells in the lung during development of ventilator-associated pneumonia

scientific article

Serum and urine cystatin C are poor biomarkers for acute kidney injury and renal replacement therapy

scientific article

Serum cystatin C-A useful endogenous marker of renal function in intensive care unit patients at risk for or with acute renal failure?

scientific article published on January 2007

Serum levels of N–terminal proB–type natriuretic peptide in mechanically ventilated critically ill patients – relation to tidal volume size and development of acute respiratory distress syndrome ⬇️

scientific article published on July 9, 2013

Should mechanical ventilation care be centralized and should we thus transfer all ventilated patients to high volume units? Take a breath first

scientific article published on 07 February 2014

Should the lungs be rested or open during anaesthesia to prevent postoperative complications?

scientific article published on 19 January 2018

Should we or should we not allow delays in antimicrobial administration? Of course not! ⬇️

scientific article published on 01 March 2012

Silver coated endotracheal tubes for prevention of ventilator-associated pneumonia in critically ill patients

scientific article

Silver-coated endotracheal tubes for prevention of ventilator-associated pneumonia in critically ill patients

scientific article published on 12 August 2015

Slurping at the inside--do not forget to clean the outside too.

scientific article

Soluble receptor for advanced glycation end products as an indicator of pulmonary vascular injury after cardiac surgery

scientific article

Soluble triggering receptor expressed on myeloid cells 1: a biomarker for bacterial meningitis

scientific article published on 20 June 2006

Soluble triggering receptor expressed on myeloid cells-1 is not a sufficient biological marker for infection of the urinary tract

scientific article published on 06 March 2007

Soluble urokinase plasminogen activator receptor for the prediction of ventilator-associated pneumonia

scientific article published on 01 February 2019

Soluble urokinase-type plasminogen activator receptor levels in patients with burn injuries and inhalation trauma requiring mechanical ventilation: an observational cohort study

scientific article

Spontaneous hypothermia on intensive care unit admission is a predictor of unfavorable neurological outcome in patients after resuscitation: an observational cohort study

scientific article

Standards for definitions and use of outcome measures for clinical effectiveness research in perioperative medicine

scientific article published on 01 February 2015

Struggle for implementation of new strategies in intensive care medicine: anticoagulation, insulin, and lower tidal volumes

scientific article

SuPAR in pleural fluid may function as a biological marker for infection in critically ill patients with pleural effusions

scientific article published on 15 February 2014

Supernatant of Aged Erythrocytes Causes Lung Inflammation and Coagulopathy in a “Two-Hit” In Vivo Syngeneic Transfusion Model

scientific article published on 01 July 2010

Supernatant of stored platelets causes lung inflammation and coagulopathy in a novel in vivo transfusion model

scientific article published on 17 May 2010

Suspended animation inducer hydrogen sulfide is protective in an in vivo model of ventilator-induced lung injury

scientific article

Sweet Spot: Glucose Control in the Intensive Care Unit

scientific article published on 28 January 2016

Symbiotics as a preventive measure against ventilator-associated pneumonia

scientific article published on 01 June 2010

Systemic and urinary neutrophil gelatinase-associated lipocalins are poor predictors of acute kidney injury in unselected critically ill patients

scientific article published on 20 October 2012

Systemic tobramycin concentrations during selective decontamination of the digestive tract in intensive care unit patients on continuous venovenous hemofiltration

scientific article published on 19 February 2008

Systemic versus localized coagulation activation contributing to organ failure in critically ill patients

scientific article published on 30 July 2011

TLR2 deficiency aggravates lung injury caused by mechanical ventilation

scientific article published on July 2014

Temporal Changes in Ventilator Settings in Patients With Uninjured Lungs: A Systematic Review

scientific article published on 01 July 2019

Tenascin C Plasma Levels in Critically Ill Patients with or Without Sepsis: A Multicentre Observational Study

scientific article published on 19 November 2019

The 25th birthday and premature death of the open lung approach?-from science, through art, towards precision medicine

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The Effects of Escalation of Respiratory Support and Prolonged Invasive Ventilation on Outcomes of Cardiac Surgical Patients: A Retrospective Cohort Study

scientific article published on 08 November 2019

The Host Response in Patients with Sepsis Developing Intensive Care Unit-acquired Secondary Infections

scientific article published on 20 January 2017

The Impact of HIV Co-Infection on the Genomic Response to Sepsis

scientific article published on 12 February 2016

The LAS VEGAS risk score for prediction of postoperative pulmonary complications: An observational study

scientific article published on 01 September 2018

The LAS VEGAS study on epidemiology, ventilator management and outcome in patients receiving intra-operative ventilation: Cohort stratified for types of surgery and airway device

scientific article published on 01 February 2021

The LUNG SAFE: a biased presentation of the prevalence of ARDS!

scientific article

The Stability and Workload Index for Transfer score predicts unplanned intensive care unit patient readmission: initial development and validation

scientific article published on March 2008

The authors respond

scientific article published on 01 January 2007

The calculation of mechanical power is not suitable for intra-patient monitoring under pressure-controlled ventilation

scientific article published on 06 February 2019

The clinical value of daily routine chest radiographs in a mixed medical-surgical intensive care unit is low.

scientific article

The clinical value of routine chest radiographs in the first 24 hours after cardiac surgery

scientific article published on 03 November 2010

The clinical value of routinely obtained postoperative chest radiographs in post-anaesthesia care unit patients seems poor-a prospective observational study

The diagnostic accuracy for ARDS of global versus regional lung ultrasound scores - a post hoc analysis of an observational study in invasively ventilated ICU patients

scientific article published on 25 July 2019

The dynamics of the pulmonary microbiome during mechanical ventilation in the intensive care unit and the association with occurrence of pneumonia.

scientific article published on 18 January 2017

The effect of blood transfusion on pulmonary permeability in cardiac surgery patients: a prospective multicenter cohort study ⬇️

scientific article published on July 11, 2011

The effects of preoperative moderate to severe anaemia on length of hospital stay: A propensity score-matched analysis in non-cardiac surgery patients

scientific article published on 04 January 2021

The extent of ventilator-induced lung injury in mice partly depends on duration of mechanical ventilation.

scientific article published on 17 April 2013

The host response in critically ill sepsis patients on statin therapy: a prospective observational study.

scientific article published on 18 January 2018

The incidence and microbial spectrum of ventilator-associated pneumonia after tracheotomy in a selective decontamination of the digestive tract-setting

scientific article published on 26 November 2007

The incidence of low venous oxygen saturation on admission to the intensive care unit: a multi-center observational study in The Netherlands.

scientific article published on 4 March 2008

The incidence, risk factors, and outcome of transfusion-related acute lung injury in a cohort of cardiac surgery patients: a prospective nested case-control study ⬇️

scientific article published on February 16, 2011

The inflammation-coagulation axis as an important intermediate pathway in acute lung injury

scientific article published on 30 April 2008

The influence of body composition on therapeutic hypothermia: a prospective observational study of patients after cardiac arrest

scientific article published on 10 July 2008

The influence of rewarming after therapeutic hypothermia on outcome after cardiac arrest ⬇️

scientific article published on April 18, 2012

The long sepsis journey in low- and middle-income countries begins with a first step...but on which road?

scientific article published on 9 March 2018

The new Surviving Sepsis Campaign recommendations on glucose control should be reconsidered

scientific article published on 20 February 2008

The potential role of exhaled breath analysis in the diagnostic process of pneumonia - a systematic review.

scientific article

The practice of and documentation on withholding and withdrawing life support: a retrospective study in two Dutch intensive care units

scientific article published in September 2009

The practice of reporting transfusion-related acute lung injury: a national survey among clinical and preclinical disciplines

scientific article published on 5 October 2009

The pulmonary protein C system: preventive or therapeutic target in acute lung injury?

scientific article published on 01 February 2009

The receptor for advanced glycation end products in ventilator-induced lung injury

scientific article published on 2 August 2014

The relationship between inflammation and the coagulation system

scientific article published on 01 March 2006

The role of bronchoalveolar hemostasis in the pathogenesis of acute lung injury

scientific article published on July 2008

The role of hypercapnia in acute respiratory failure

scientific article published on 25 July 2019

The tidal volume fix and more…

scientific article published on 01 August 2019

The volatile metabolic fingerprint of ventilator-associated pneumonia

scientific article published on 11 March 2014

There is more than tidal volumes in mechanical ventilation

scientific article published in May 2015

Thrombocytopenia impairs host defense during murine Streptococcus pneumoniae pneumonia

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Thrombocytopenia is associated with a dysregulated host response in critically ill sepsis patients

scientific article

Tidal Volume Ventilation Strategy in ICU Patients Without ARDS-Reply

scientific article published on 01 April 2019

Tight glycaemic control: a survey of intensive care practice in the Netherlands

scientific article published on 25 February 2006

Tight glycaemic control: intelligent technology or a nurse-wise strategy?

scientific article published in January 2007

Time to wean after tracheotomy differs among subgroups of critically ill patients: retrospective analysis in a mixed medical/surgical intensive care unit

scientific article published on 01 December 2006

Timing of drotrecogin alfa (activated) treatment in severe sepsis

scientific article published on January 2006

Timing of tracheostomy in adult patients: conclusions may be premature

scientific article published on August 2005

Tracheostomy During the COVID-19 Pandemic: Comparison of International Perioperative Care Protocols and Practices in 26 Countries

scientific article published on 03 November 2020

Tracheotomy does not affect reducing sedation requirements of patients in intensive care--a retrospective study

scientific article published on January 2006

Transfusion and mechanical ventilation: two interrelated causes of acute lung injury?

scientific article

Transfusion of platelets, but not of red blood cells, is independently associated with nosocomial infections in the critically ill. ⬇️

scientific article published on 19 July 2016

Transfusion-related acute lung injury in cardiac surgery patients is characterized by pulmonary inflammation and coagulopathy: a prospective nested case-control study

scientific article published in October 2012

Traumatic brain injury in rats induces lung injury and systemic immune suppression

scientific article

Treatment of hypophosphatemia in the intensive care unit: a review.

scientific article published on 03 August 2010

Treatment with broadly neutralizing influenza antibodies reduces severity of secondary pneumococcal pneumonia in mice

scientific article published on 12 June 2018

Tumor necrosis factor receptor 1 (TNFRI) for ventilator-associated pneumonia diagnosis by cytokine multiplex analysis

scientific article published on 16 September 2015

Two cases of tetanus?

scientific article published on 01 November 2006

Ultra-low-dose sequential computed tomography for quantitative lung aeration assessment-a translational study

scientific article published on 4 April 2017

Understanding Heterogeneity in Biologic Phenotypes of Acute Respiratory Distress Syndrome by Leukocyte Expression Profiles

scientific article published on 01 July 2019

Updated guidance on the management of COVID-19: from an American Thoracic Society/European Respiratory Society coordinated International Task Force (29 July 2020)

scientific article published on 01 September 2020

Usefulness of suPAR as a biological marker in patients with systemic inflammation or infection: a systematic review

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Validation of a Host Response Assay, Septicyte™ LAB, for Discriminating Sepsis from SIRS in the ICU.

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Validation of a Novel Molecular Host Response Assay to Diagnose Infection in Hospitalized Patients Admitted to the ICU With Acute Respiratory Failure

scientific article published in March 2018

Validation of a novel surveillance paradigm for ventilator-associated events

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Variable versus conventional lung protective mechanical ventilation during open abdominal surgery: study protocol for a randomized controlled trial

scientific article published on 2 May 2014

Variation in Definition of Prolonged Mechanical Ventilation.

scientific article published on 13 June 2017

Ventilation management and clinical outcomes in invasively ventilated patients with COVID-19 (PRoVENT-COVID): a national, multicentre, observational cohort study

scientific article published on 23 October 2020

Ventilation with high versus low peep levels during general anaesthesia for open abdominal surgery does not affect postoperative spirometry: A randomised clinical trial.

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Ventilation with lower tidal volumes as compared with conventional tidal volumes for patients without acute lung injury: a preventive randomized controlled trial

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Ventilation with lower tidal volumes for critically ill patients without the acute respiratory distress syndrome: a systematic translational review and meta-analysis

scientific article published on February 2014

Ventilator-Associated Pneumonia Reduced—Mortality Untouched ⬇️

scientific article published on June 1, 2013

Ventilator-associated pneumonia prevention: WHAP, positive end-expiratory pressure, or both?

scientific article published on 01 August 2008

Ventilator-induced lung injury is mediated by the NLRP3 inflammasome

scientific article published in May 2012

Ventilatory support of patients with sepsis or septic shock in resource-limited settings

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Volatile metabolites of pathogens: a systematic review

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Volatile organic compound profiles in outlet air from extracorporeal life-support devices differ from breath profiles in critically ill patients

scientific article published on 01 April 2019

Walking the line between benefit and harm from tracheostomy in COVID-19

scientific article published on 15 May 2020

Weaning automation with adaptive support ventilation: a randomized controlled trial in cardiothoracic surgery patients

scientific article published in February 2009

Weaning from mechanical ventilation: stay poised between load and strength

scientific article published on 01 August 2010

What do sepsis-induced coagulation test result abnormalities mean to intensivists?

scientific article published on 20 February 2017

What tidal volumes should be used in patients without acute lung injury?

scientific article published on June 2007

What's new in ARDS: ARDS also exists in resource-constrained settings

scientific article published on 16 March 2016

Why translational research matters: proceedings of the third international symposium on acute lung injury translational research (INSPIRES III)

scientific article published on 25 July 2019

Year in review 2006: Critical Care--Resource management.

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