List of works - Tsutomu Shimada

Activation of procarcinogens by human cytochrome P450 enzymes ⬇️

scientific article published on May 25, 1998

Characterization of cytochrome P450 enzymes involved in drug oxidations in mouse intestinal microsomes

scientific article published in October 2000

Contributions of human liver cytochrome P450 enzymes to the N-oxidation of 4,4′-methylene-bis(2-chloroaniline) ⬇️

scientific article published on February 1, 1992

Cytochrome P450 2A6 and other human P450 enzymes in the oxidation of flavone and flavanone.

scientific article

Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes

scientific article published on October 1, 1992

Cytochrome P450 Reconstitution Systems

scientific article published on 01 January 1998

Docking and QSAR comparative studies of polycyclic aromatic hydrocarbons and other procarcinogen interactions with cytochromes P450 1A1 and 1B1 ⬇️

scientific article published on December 8, 2011

Dose-response studies on the induction of liver cytochromes P4501A1 and 1B1 by polycyclic aromatic hydrocarbons in arylhydrocarbon-responsive C57BL/6J mice ⬇️

scientific article published on September 1, 2003

Effects of arachidonic acid, prostaglandins, retinol, retinoic acid and cholecalciferol on xenobiotic oxidations catalysed by human cytochrome P450 enzymes

Elucidation of catalytic specificities of human cytochrome P450 and glutathione S-transferase enzymes and relevance to molecular epidemiology ⬇️

scientific article published on November 1, 1992

Ethnic-related differences in the frequency distribution of genetic polymorphisms in the CYP1A1 and CYP1B1 genes in Japanese and Caucasian populations

Inhibition of human cytochrome P450 1A1-, 1A2-, and 1B1-mediated activation of procarcinogens to genotoxic metabolites by polycyclic aromatic hydrocarbons

Inhibition of mono-oxygenase activities by 1,1,1-trichloropropene 2,3-oxide, an inhibitor of epoxide hydrase, in rat liver microsomes

scientific article published on 01 June 1979

Mutagenic Activation of 3-Methoxy-4-aminoazobenzene by Mouse Renal Cytochrome-P450 CYP4B1: Cloning and Characterization of Mouse CYP4B1 ⬇️

scientific article published on August 1, 1995

Nicotinamide N-oxide formation by rat liver microsomes ⬇️

scientific article published on 01 March 1983

Oxidation of 1-chloropyrene by human CYP1 family and CYP2A subfamily cytochrome P450 enzymes: catalytic roles of two CYP1B1 and five CYP2A13 allelic variants.

scientific article published on 21 July 2017

Participation of rat liver cytochrome P450 2E1 in the activation of N-nitrosodimethylamine and N-nitrosodiethylainine to products genotoxic in an acetyltransferase–overexpressing Salmonella typhimurium strain (NM2009) ⬇️

scientific article published on June 1, 1992

Possible occurrence of P450 related to P450 HFLb in extrahepatic tissues of human fetuses and its contribution to metabolic activation of promutagens ⬇️

scientific article published on 01 October 1994

Role of phospholipids in reconstituted cytochrome P 450 3A form and mechanism of their activation of catalytic activity ⬇️

scientific article (publication date: 7 July 1992)

Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2',5'-Tetrachlorobiphenyl

scientific article published on 13 September 2016

Spectral Modification and Catalytic Inhibition of Human Cytochromes P450 1A1, 1A2, 1B1, 2A6, and 2A13 by Four Chemopreventive Organoselenium Compounds ⬇️

scientific article published on July 20, 2011

Structure-Function Studies of Naphthalene, Phenanthrene, Biphenyl, and Their Derivatives in Interaction with and Oxidation by Cytochromes P450 2A13 and 2A6.

scientific article published on 3 May 2016

List of works by Tsutomu Shimada