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List of works by Samuel H Speck

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Efficient transcription of the Epstein-Barr virus immediate-early BZLF1 and BRLF1 genes requires protein synthesis

scientific article published on December 1991
Host-cell-determined methylation of specific Epstein-Barr virus promoters regulates the choice between distinct viral latency programs

scientific article published on January 1997
Disruption of gammaherpesvirus 68 gene 50 demonstrates that Rta is essential for virus replication

scientific article
Murine gammaherpesvirus 68 encodes a functional regulator of complement activation

scientific article
Antibody to a lytic cycle viral protein decreases gammaherpesvirus latency in B-cell-deficient mice

scientific article published on November 2002
Critical role of complement and viral evasion of complement in acute, persistent, and latent gamma-herpesvirus infection

scientific article published on August 2002
The murine gammaherpesvirus 68 v-cyclin gene is an oncogene that promotes cell cycle progression in primary lymphocytes

scientific article
Gammaherpesvirus-driven plasma cell differentiation regulates virus reactivation from latently infected B lymphocytes

scientific article
Identification of infected B-cell populations by using a recombinant murine gammaherpesvirus 68 expressing a fluorescent protein

scientific article published on 22 April 2009
Binding of the ubiquitous cellular transcription factors Sp1 and Sp3 to the ZI domains in the Epstein-Barr virus lytic switch BZLF1 gene promoter

scientific article published on February 1997
ZEBRA and a Fos-GCN4 chimeric protein differ in their DNA-binding specificities for sites in the Epstein-Barr virus BZLF1 promoter

scientific article published on August 1, 1991
Ongoing viral replication is required for gammaherpesvirus 68-induced vascular damage

scientific article
Complex transcription of the Epstein-Barr virus BamHI fragment H rightward open reading frame 1 (BHRF1) in latently and lytically infected B lymphocytes

scientific article
A gammaherpesvirus-secreted activator of Vbeta4+ CD8+ T cells regulates chronic infection and immunopathology

scientific article published on 10 March 2008
The murine gammaherpesvirus 68 M2 gene is required for efficient reactivation from latently infected B cells

scientific article
Synergistic autoactivation of the Epstein-Barr virus immediate-early BRLF1 promoter by Rta and Zta.

scientific article published on June 2003
Regulation of the BZLF1 promoter of Epstein-Barr virus by second messengers in anti-immunoglobulin-treated B cells

scientific article
Identification and initial characterization of the murine gammaherpesvirus 68 gene M3, encoding an abundantly secreted protein

scientific article published on May 1999
Identification of a Negative cis Element within the ZII Domain of the Epstein-Barr Virus Lytic Switch BZLF1 Gene Promoter

scientific article published on October 1, 1998
A surface groove essential for viral Bcl-2 function during chronic infection in vivo

scientific article
An optimized CD4 T-cell response can control productive and latent gammaherpesvirus infection

scientific article
Effective vaccination against long-term gammaherpesvirus latency

scientific article
The MHV68 M2 protein drives IL-10 dependent B cell proliferation and differentiation

scientific article
Signaling through Toll-like receptors induces murine gammaherpesvirus 68 reactivation in vivo

scientific article published on 19 November 2008
Definition of cytochrome c binding domains by chemical modification: Kinetics of reaction with beef mitochondrial reductase and functional organization of the respiratory chain

scientific article published on January 1, 1979
Tracking Murine Gammaherpesvirus 68 Infection of Germinal Center B Cells In Vivo

scientific article published on March 13, 2012
Epstein-Barr virus BZLF1 trans activator induces the promoter of a cellular cognate gene, c-fos

scientific article published on September 1990
Differential methylation of Epstein-Barr virus latency promoters facilitates viral persistence in healthy seropositive individuals.

scientific article published on December 1999
Characterization of the ZI domains in the Epstein-Barr virus BZLF1 gene promoter: role in phorbol ester induction

scientific article published in June 1996
ORF73-null murine gammaherpesvirus 68 reveals roles for mLANA and p53 in virus replication

scientific article published on 15 August 2007
A gammaherpesvirus 68 gene 50 null mutant establishes long-term latency in the lung but fails to vaccinate against a wild-type virus challenge.

scientific article
Establishment of B-cell lines latently infected with reactivation-competent murine gammaherpesvirus 68 provides evidence for viral alteration of a DNA damage-signaling cascade

scientific article published on 21 May 2008
DNA-binding-defective mutants of the Epstein-Barr virus lytic switch activator Zta transactivate with altered specificities

scientific article published on May 1994
Role for MyD88 signaling in murine gammaherpesvirus 68 latency

scientific article
Maintenance of gammaherpesvirus latency requires viral cyclin in the absence of B lymphocytes

scientific article
Isolation and characterization of cDNA clones corresponding to transcripts from the BamHI H and F regions of the Epstein-Barr virus genome

scientific article
Characterization of a spontaneous 9.5-kilobase-deletion mutant of murine gammaherpesvirus 68 reveals tissue-specific genetic requirements for latency

scientific article
Role of B-cell proliferation in the establishment of gammaherpesvirus latency

scientific article
Alternative splicing dictates translational start in Epstein-Barr virus transcripts

scientific article
The Epstein-Barr virus BamHI F promoter is an early lytic promoter: lack of correlation with EBNA 1 gene transcription in group 1 Burkitt's lymphoma cell lines

scientific article
NF-kappaB p50 plays distinct roles in the establishment and control of murine gammaherpesvirus 68 latency

scientific article published on 04 March 2009
Alternatively initiated gene 50/RTA transcripts expressed during murine and human gammaherpesvirus reactivation from latency

scientific article published on 29 October 2008
Transcription of the tumor necrosis factor alpha gene is rapidly induced by anti-immunoglobulin and blocked by cyclosporin A and FK506 in human B cells

scientific article published on December 15, 1992
Murine Gammaherpesvirus M2 Protein Induction of IRF4 via the NFAT Pathway Leads to IL-10 Expression in B Cells

scientific article published on January 2, 2014
Identification of candidate gammaherpesvirus 68 genes required for virus replication by signature-tagged transposon mutagenesis

scientific article published in October 2004
Ex vivo stimulation of B cells latently infected with gammaherpesvirus 68 triggers reactivation from latency

scientific article
Disruption of the gene encoding the gammaHV68 v-GPCR leads to decreased efficiency of reactivation from latency

scientific article published in March 2003
Regulation of EBNA gene transcription in lymphoblastoid cell lines: characterization of sequences downstream of BCR2 (Cp).

scientific article
Antibody-independent control of gamma-herpesvirus latency via B cell induction of anti-viral T cell responses

scientific article published on 23 June 2006
The reaction of primate cytochromes c with cytochrome c oxidase. Analysis of the polarographic assay

scientific article published on May 10, 1983

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