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List of works by Georg-Wilhelm Bornkamm

12/15-lipoxygenase-derived lipid peroxides control receptor tyrosine kinase signaling through oxidation of protein tyrosine phosphatases

scientific article

A computer-assisted two-dimensional gel electrophoresis approach for studying the variations in protein expression related to an induced functional repression of NFkB in lymphoblastoid cell lines

AP4 is a mediator of epithelial-mesenchymal transition and metastasis in colorectal cancer

scientific article published on 10 June 2013

Activated Notch1 alters differentiation of embryonic stem cells into mesodermal cell lineages at multiple stages of development

scientific article published on 25 May 2006

Active NF-kappaB signalling is a prerequisite for influenza virus infection.

scientific article published on August 2004

Alternative splicing generates putative soluble CD83 proteins that inhibit T cell proliferation

scientific article

An Epstein-Barr virus anti-apoptotic protein constitutively expressed in transformed cells and implicated in burkitt lymphomagenesis: the Wp/BHRF1 link

scientific article published in March 2009

Autoactivation of the Epstein-Barr virus oncogenic protein LMP1 during type II latency through opposite roles of the NF-kappaB and JNK signaling pathways

scientific article published on August 2006

B-cell-specific elements enhance sustained gene expression mediated by self-replicating extrachromosomal vectors ⬇️

scientific article published on 01 July 2010

B1 and Marginal Zone B Cells but Not Follicular B2 Cells Require Gpx4 to Prevent Lipid Peroxidation and Ferroptosis

scientific article published on 01 November 2019

Burkitt lymphoma: the role of Epstein‐Barr virus revisited ⬇️

scientific article published on March 1, 2012

C-myc activation impairs the NF-kappaB and the interferon response: implications for the pathogenesis of Burkitt's lymphoma

scientific article published on April 2007

Combined deficiency in glutathione peroxidase 4 and vitamin E causes multiorgan thrombus formation and early death in mice

scientific article published on 14 June 2013

Control of Epstein-Barr virus infection in vitro by T helper cells specific for virion glycoproteins.

scientific article

Control of Epstein–Barr virus reactivation by activated CD40 and viral latent membrane protein 1 ⬇️

scientific article published on December 18, 2001

Cytoplasmic thioredoxin reductase is essential for embryogenesis but dispensable for cardiac development

scientific journal article

Differential roles of STAT1alpha and STAT1beta in fludarabine-induced cell cycle arrest and apoptosis in human B cells

scientific article

EBV latency III immortalization program sensitizes B cells to induction of CD95-mediated apoptosis via LMP1: role of NF-kappaB, STAT1, and p53.

scientific article published on 29 November 2005

Efficient generation and expansion of antigen-specific CD4+ T cells by recombinant influenza viruses

scientific article published on December 2003

Elevation of c-MYC disrupts HLA class II-mediated immune recognition of human B cell tumors

scientific article

Embryonic expression profile of phospholipid hydroperoxide glutathione peroxidase

scientific article published on 2 February 2006

Endogenous presentation of a nuclear antigen on MHC class II by autophagy in the absence of CRM1-mediated nuclear export

scientific article

Epstein-Barr virus and its role in the pathogenesis of Burkitt's lymphoma: an unresolved issue

scientific article published on 18 July 2009

Epstein-Barr virus and the pathogenesis of Burkitt's lymphoma: more questions than answers

scientific article

Epstein-Barr virus latent membrane protein 2A mimics B-cell receptor-dependent virus reactivation

scientific article

Epstein-Barr virus nuclear antigen 1 evades direct immune recognition by CD4+ T helper cells

scientific article published on September 2004

Essential role for mitochondrial thioredoxin reductase in hematopoiesis, heart development, and heart function

scientific article

Glutathione peroxidase 4 and vitamin E control reticulocyte maturation, stress erythropoiesis and iron homeostasis

scientific article published on 27 June 2019

Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors

scientific article published on 13 October 2015

Glutathione peroxidase 4 senses and translates oxidative stress into 12/15-lipoxygenase dependent- and AIF-mediated cell death

scientific article

Humanized c-Myc mouse

scientific article

Identification of Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA2) target proteins by proteome analysis: activation of EBNA2 in conditionally immortalized B cells reflects early events after infection of primary B cells by EBV.

scientific article published on April 2004

Identification of MHC II-Restricted Minor Histocompatibility Antigens After HLA-Identical Stem-Cell Transplantation ⬇️

scientific article published on November 15, 2010

Immunodominance of lytic cycle antigens in Epstein-Barr virus-specific CD4+ T cell preparations for therapy

scientific article

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

scientific article

Latent membrane protein 1 of Epstein-Barr virus induces CD83 by the NF-kappaB signaling pathway

scientific article

Latent membrane protein 1 regulates STAT1 through NF-kappaB-dependent interferon secretion in Epstein-Barr virus-immortalized B cells

scientific article

Loss of thioredoxin reductase 1 renders tumors highly susceptible to pharmacologic glutathione deprivation

scientific article published on 2 November 2010

MYC overexpression imposes a nonimmunogenic phenotype on Epstein-Barr virus-infected B cells

scientific article

Major histocompatibility complex class II-restricted presentation of a cytosolic antigen by autophagy

scientific article published on May 2003

Mammalian WDR12 is a novel member of the Pes1-Bop1 complex and is required for ribosome biogenesis and cell proliferation

scientific article

Mitochondrial and cytosolic thioredoxin reductase knockout mice

Mouse Genetics Suggests Cell-Context Dependency for Myc-Regulated Metabolic Enzymes during Tumorigenesis ⬇️

scientific article published on March 15, 2012

Mutations in the mitochondrial thioredoxin reductase gene TXNRD2 cause dilated cardiomyopathy

scientific article

Neuronal selenoprotein expression is required for interneuron development and prevents seizures and neurodegeneration

scientific journal article

Novel function of STAT1beta in B cells: induction of cell death by a mechanism different from that of STAT1alpha.

scientific article

Optimized vector for conditional gene targeting in mouse embryonic stem cells

scientific article

Physiological role of phospholipid hydroperoxide glutathione peroxidase in mammals

scientific article

Rapid conditional knock-down-knock-in system for mammalian cells

scientific article published on 14 December 2006

Recombination signal sequence-binding protein Jkappa alters mesodermal cell fate decisions by suppressing cardiomyogenesis

scientific article

Requirements for control of B-cell lymphoma by NK cells

scientific article

STAT1-dependent IgG cell-surface expression in a human B cell line derived from a STAT1-deficient patient

scientific article

Selenium deficiency abrogates inflammation-dependent plasma cell tumors in mice

scientific article published in April 2004

Stringent doxycycline-dependent control of gene activities using an episomal one-vector system

scientific article

Stromal interferon-γ signaling and cross-presentation are required to eliminate antigen-loss variants of B cell lymphomas in mice

scientific article (publication date: 2012)

Suppression of the tumorigenic growth of Burkitt's lymphoma cells in immunodeficient mice by cytokine gene transfer using EBV-derived episomal expression vectors

article

System x(c)- and thioredoxin reductase 1 cooperatively rescue glutathione deficiency

scientific article published on 12 May 2010

T cell lipid peroxidation induces ferroptosis and prevents immunity to infection.

scientific article

Targeting c-MYC with T-cells

scientific article

Targeting high-grade B cell lymphoma with CD19-specific T cells

scientific article published on 20 February 2014

Testis-specific expression of the nuclear form of phospholipid hydroperoxide glutathione peroxidase (PHGPx).

scientific article published in April 2003

The infectious kiss: newly infected B cells deliver Epstein-Barr virus to epithelial cells

scholarly article

The role of virus-specific CD4+ T cells in the control of Epstein-Barr virus infection ⬇️

scientific article published on April 1, 2011

The thioredoxin-1 and glutathione/glutaredoxin-1 systems redundantly fuel murine B-cell development and responses

scientific article published on 01 March 2019

Virus and autoantigen-specific CD4+ T cells are key effectors in a SCID mouse model of EBV-associated post-transplant lymphoproliferative disorders

scientific article

c-MYC impairs immunogenicity of human B cells

scientific article published on January 2007

c-Myc and Rel/NF-kappaB are the two master transcriptional systems activated in the latency III program of Epstein-Barr virus-immortalized B cells

scientific article published on 04 March 2009

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