Search filters

List of works by Margaret Sullivan Pepe

A Framework for Evaluating Markers Used to Select Patient Treatment ⬇️

scientific article published on June 27, 2013

A Randomized Study Comparing Digital Imaging to Traditional Glass Slide Microscopy for Breast Biopsy and Cancer Diagnosis

scientific article published on 10 March 2017

A data-analytic strategy for protein biomarker discovery: profiling of high-dimensional proteomic data for cancer detection

scientific article

A framework for evaluating diagnostic discordance in pathology discovered during research studies

scientific article

A practical multifaceted approach to selecting differentially expressed genes

scientific article published on January 2007

Accommodating Covariates in ROC Analysis

scientific article published on January 2009

Adding Rigor to Biomarker Evaluations - EDRN Experience

scientific article published on 10 November 2020

Adjusting for covariate effects on classification accuracy using the covariate-adjusted receiver operating characteristic curve

scientific article

Adjusting for covariates in studies of diagnostic, screening, or prognostic markers: an old concept in a new setting

scientific article published on 13 May 2008

Adopting nested case–control quota sampling designs for the evaluation of risk markers ⬇️

scientific article published on June 27, 2013

An approach to evaluating and comparing biomarkers for patient treatment selection

scientific article published on 01 January 2014

Assessing the value of risk predictions by using risk stratification tables

scientific article

Assessment of Second-Opinion Strategies for Diagnoses of Cutaneous Melanocytic Lesions

scientific article published on 02 October 2019

Association Between Benign Breast Disease in African American and White American Women and Subsequent Triple-Negative Breast Cancer

scientific article published on 22 December 2016

Combining biomarkers to detect disease with application to prostate cancer ⬇️

scientific article published on October 1, 2003

Commentary: Reporting standards are needed for evaluations of risk reclassification ⬇️

scientific article published on May 13, 2011

Comparing the predictive values of diagnostic tests: sample size and analysis for paired study designs

scientific article published in January 2006

Concordance and Reproducibility of Melanoma Staging According to the 7th vs 8th Edition of the AJCC Cancer Staging Manual

scientific article published on 01 May 2018

Construction and analysis of the NCI-EDRN breast cancer reference set for circulating markers of disease

scientific article

Designing a study to evaluate the benefit of a biomarker for selecting patient treatment

scientific article

Development of a diagnostic test set to assess agreement in breast pathology: practical application of the Guidelines for Reporting Reliability and Agreement Studies (GRRAS).

scientific article

Diagnostic Reproducibility: What Happens When the Same Pathologist Interprets the Same Breast Biopsy Specimen at Two Points in Time?

scientific article

Diagnostic concordance among pathologists interpreting breast biopsy specimens

scientific article published in March 2015

Discordant Interpretations of Breast Biopsy Specimens by Pathologists--Reply

scientific article published in July 2015

Do erythropoietin receptors on cancer cells explain unexpected clinical findings?

scientific article published on 01 October 2006

Does the Net Reclassification Improvement Help Us Evaluate Models and Markers?

article

Early-Phase Studies of Biomarkers: What Target Sensitivity and Specificity Values Might Confer Clinical Utility?

scientific article published on 21 March 2016

Effect of recombinant canine granulocyte-macrophage colony-stimulating factor on hematopoietic recovery after otherwise lethal total body irradiation

scientific article published on 01 April 1994

Effects of recombinant canine stem cell factor, a c-kit ligand, and recombinant granulocyte colony-stimulating factor on hematopoietic recovery after otherwise lethal total body irradiation ⬇️

scientific article published on 01 January 1993

Endoscopic ultrasound, positron emission tomography, and computerized tomography for lung cancer

scientific article published on 06 August 2003

Estimation and Comparison of Receiver Operating Characteristic Curves

scientific article published on March 2009

Evaluating the ROC performance of markers for future events

scientific article published on 7 December 2007

Evaluation of 12 strategies for obtaining second opinions to improve interpretation of breast histopathology: simulation study

scientific article published on 22 June 2016

Further insight into the incremental value of new markers: the interpretation of performance measures and the importance of clinical context

scientific article published on 8 August 2012

Gauging the performance of SNPs, biomarkers, and clinical factors for predicting risk of breast cancer

scientific article published on 8 July 2008

Identifying target populations for screening or not screening using logic regression

scientific article published on 01 May 2005

Improving Biomarker Identification with Better Designs and Reporting ⬇️

scientific article published on August 1, 2011

Improving risk classification of critical illness with biomarkers: a simulation study

scientific article published on 06 April 2013

Improving the quality of biomarker discovery research: the right samples and enough of them

scientific article published on 2 April 2015

Inactivation of p16, RUNX3, and HPP1 occurs early in Barrett's-associated neoplastic progression and predicts progression risk

scientific article (publication date: 9 June 2005)

Integrating the predictiveness of a marker with its performance as a classifier

scientific article

Joint modeling, covariate adjustment, and interaction: contrasting notions in risk prediction models and risk prediction performance

scientific article published on November 2011

LOGISTIC REGRESSION ANALYSIS WITH STANDARDIZED MARKERS.

scientific article published on September 2013

Letter by Pepe et al regarding article, "Use and misuse of the receiver operating characteristic curve in risk prediction"

scientific article published on 01 August 2007

Matching in studies of classification accuracy: implications for analysis, efficiency, and assessment of incremental value

scientific article published on 14 May 2007

Measures to summarize and compare the predictive capacity of markers.

scientific article

Measuring the Performance of Markers for Guiding Treatment Decisions ⬇️

scientific article published on February 15, 2011

Methods for Assessing Improvement in Specificity when a Biomarker is Combined with a Standard Screening Test

scientific article

Net reclassification indices for evaluating risk prediction instruments: a critical review

scientific article published on January 2014

Net risk reclassification p values: valid or misleading?

scientific article published on 28 March 2014

Partial AUC Estimation and Regression ⬇️

scientific article published on September 1, 2003

Partially supervised learning using an EM-boosting algorithm

scientific article published in March 2004

Pathologist characteristics associated with accuracy and reproducibility of melanocytic skin lesion interpretation

scientific article published on 7 March 2018

Pathologists' diagnosis of invasive melanoma and melanocytic proliferations: observer accuracy and reproducibility study

scientific article

Pivotal evaluation of the accuracy of a biomarker used for classification or prediction: standards for study design

scientific article published on 07 October 2008

Postprandial suppression of plasma ghrelin level is proportional to ingested caloric load but does not predict intermeal interval in humans

scientific article published on 01 March 2004

Problems With Risk Reclassification Methods for Evaluating Prediction Models ⬇️

scientific article published on May 9, 2011

Quantifying and comparing the accuracy of binary biomarkers when predicting a failure time outcome

scientific article published on 01 May 2004

Quantifying and comparing the predictive accuracy of continuous prognostic factors for binary outcomes

scientific article published on 01 January 2004

Re: "Clinical Usefulness of the Framingham Cardiovascular Risk Profile beyond Its Statistical Performance: The Tehran Lipid and Glucose Study" ⬇️

scientific article published on March 22, 2013

Recommendation to use exact P-values in biomarker discovery research in place of approximate P-values

scientific article published on 10 August 2018

Sample size calculations for comparative studies of medical tests for detecting presence of disease

scientific article published in March 2002

Second opinion strategies in breast pathology: a decision analysis addressing over-treatment, under-treatment, and care costs.

scientific article published on 6 September 2017

Statistical inference for net benefit measures in biomarker validation studies

scientific article published on 16 November 2019

The Early Detection Research Network's Specimen Reference Sets: Paving the Way for Rapid Evaluation of Potential Biomarkers ⬇️

scientific article published on November 27, 2012

The Fundamental Difficulty With Evaluating the Accuracy of Biomarkers for Guiding Treatment

scientific article

The Net Reclassification Index (NRI): a Misleading Measure of Prediction Improvement Even with Independent Test Data Sets

scientific article

The diagnostic challenge of low-grade ductal carcinoma in situ

scientific article published on 20 May 2017

The optimal ratio of cases to controls for estimating the classification accuracy of a biomarker

scientific article published on 20 January 2006

The potential of genes and other markers to inform about risk

scientific article

Time-dependent Predictive Values of Prognostic Biomarkers with Failure Time Outcome.

scientific article published on January 2008

Using the ROC curve for gauging treatment effect in clinical trials

scientific article

Variability in Pathologists' Interpretations of Individual Breast Biopsy Slides: A Population Perspective

scientific article published on 22 March 2016

Paulina is supported by:

About Paulina

Help