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List of works by Włodzimierz Krzyżosiak

2D and 3D FISH of expanded repeat RNAs in human lymphoblasts.

scientific article published on 9 April 2017

A Potential Role of Extended Simple Sequence Repeats in Competing Endogenous RNA Crosstalk

scholarly article by Tomasz Witkos published in November 2018

A new humanized ataxin-3 knock-in mouse model combines the genetic features, pathogenesis of neurons and glia and late disease onset of SCA3/MJD.

scientific article published on 7 October 2014

Accurate and sensitive analysis of triplet repeat expansions by capillary electrophoresis

scientific article published in June 2005

An evaluation of oligonucleotide-based therapeutic strategies for polyQ diseases

scientific article

Analysis of MicroRNA Length Variety Generated by Recombinant Human Dicer ⬇️

scientific article published on January 1, 2013

Artificial miRNAs targeting CAG repeat expansion in ORFs cause rapid deadenylation and translation inhibition of mutant transcripts

scientific article published on 21 July 2020

Atomic resolution structure of CAG RNA repeats: structural insights and implications for the trinucleotide repeat expansion diseases

scientific article

CAG and CTG repeat polymorphism in exons of human genes shows distinct features at the expandable loci

scientific article published on 01 May 2007

CAG repeat RNA as an auxiliary toxic agent in polyglutamine disorders ⬇️

scientific article published on July 1, 2011

CAG repeats mimic CUG repeats in the misregulation of alternative splicing

scientific article published on 27 July 2011

Cellular toxicity of expanded RNA repeats: focus on RNA foci ⬇️

scientific article published on 04 July 2011

Coiled-coil motifs enhance the toxicity of polyQ proteins (comment on DOI 10.1002/bies.201300001).

scientific article published in June 2013

Cooperation meets competition in microRNA-mediated DMPK transcript regulation

scientific article

Copy number variation of microRNA genes in the human genome

scientific article

Crystal structures of CGG RNA repeats with implications for fragile X-associated tremor ataxia syndrome

scientific article

Crystallographic characterization of CCG repeats

scientific article

Current understanding of the role of microRNAs in spinocerebellar ataxias

scientific article

Diced Triplets Expose Neurons to RISC ⬇️

scientific article published on February 23, 2012

Discriminating RNA variants with single-molecule allele-specific FISH.

scientific article published on 14 September 2016

Economical protocol for combined single-strand conformation polymorphism and heteroduplex analysis on a standard capillary electrophoresis apparatus

scientific article published on January 2010

Expression characteristics of triplet repeat-containing RNAs and triplet repeat-interacting proteins in human tissues

scientific article published on 30 January 2008

Facile FMR1 mRNA structure regulation by interruptions in CGG repeats

scientific article

Genotyping of simple sequence repeats--factors implicated in shadow band generation revisited

scientific article published on 01 October 2006

Germline Mutations in BRCA1 and BRCA2 in Polish Families Predisposed to Breast and Ovary Cancers.

scientific article published in January 1999

Hairpin structure within the 3'UTR of DNA polymerase beta mRNA acts as a post-transcriptional regulatory element and interacts with Hax-1

scientific article

High-Resolution Northern Blot for a Reliable Analysis of MicroRNAs and Their Precursors ⬇️

scientific article published on January 5, 2011

Huntington disease iPSCs show early molecular changes in intracellular signaling, the expression of oxidative stress proteins and the p53 pathway

scientific article

Identifying proteins that bind to specific RNAs - focus on simple repeat expansion diseases

scientific article published on 12 September 2016

In Vitro Expansion of CAG, CAA, and Mixed CAG/CAA Repeats

scientific article

Inhibition of mutant huntingtin expression by RNA duplex targeting expanded CAG repeats

scientific article published on 22 March 2011

Molecular architecture of CAG repeats in human disease related transcripts

scientific article published in July 2004

Mouse ataxin-3 functional knock-out model.

scientific article published on 14 October 2010

Mouse models of polyglutamine diseases in therapeutic approaches: review and data table. Part II.

scientific article

Mouse models of polyglutamine diseases: review and data table. Part I

scientific article

Mutant CAG Repeats Effectively Targeted by RNA Interference in SCA7 Cells

scientific article published on 17 December 2016

Mutant CAG repeats of Huntingtin transcript fold into hairpins, form nuclear foci and are targets for RNA interference

scientific article published on 18 January 2011

Northern blotting analysis of microRNAs, their precursors and RNA interference triggers

scientific article

Nuclear speckles are detention centers for transcripts containing expanded CAG repeats.

scientific article

Nuclear speckles: molecular organization, biological function and role in disease

scientific article published on September 2017

Nucleotide sequence of miRNA precursor contributes to cleavage site selection by Dicer

scientific article

Oligonucleotide-based strategies to combat polyglutamine diseases

scientific article

Optimum sample medium for single-nucleotide polymorphism and mutation detection by capillary electrophoresis.

scientific article

Pathogenesis of spinocerebellar ataxias viewed from the RNA perspective

scientific article

Patterns of CAG repeat interruptions in SCA1 and SCA2 genes in relation to repeat instability

scientific article published in September 2004

Precise Excision of the CAG Tract from the Huntingtin Gene by Cas9 Nickases.

scientific article published on 26 February 2018

Pseudouridylation of U(35) in the anticodon of Arabidopsis thaliana pre-tRNA(Tyr) depends on length rather than structure of an intron

scientific article published in March 2002

RAN translation and frameshifting as translational challenges at simple repeats of human neurodegenerative disorders

scientific article

RNA FISH for detecting expanded repeats in human diseases

scientific article published on 23 November 2015

RNA imaging in living cells - methods and applications

scientific article

RNA structure analysis assisted by capillary electrophoresis

scientific article published in November 2002

RNA structure of trinucleotide repeats associated with human neurological diseases

scientific article

RNA toxicity in polyglutamine disorders: concepts, models, and progress of research

scientific article published on 20 March 2013

RNAimmuno: a database of the nonspecific immunological effects of RNA interference and microRNA reagents

scientific article published on 12 March 2012

Rapid heteroduplex analysis by capillary electrophoresis

scientific article published in March 2005

Recent advances in understanding of the immunological off-target effects of siRNA.

scientific article published on December 2011

Reduction of Huntington's Disease RNA Foci by CAG Repeat-Targeting Reagents

scientific article published on 28 March 2017

Regulation of huntingtin gene expression by miRNA-137, -214, -148a, and their respective isomiRs

scientific article published on 19 August 2013

Repetitive sequences that shape the human transcriptome

scientific article published on June 2004

Ribonuclease dicer cleaves triplet repeat hairpins into shorter repeats that silence specific targets

scientific article published on 01 February 2007

Self-duplexing CUG repeats selectively inhibit mutant huntingtin expression

scientific article published on 13 September 2013

Sequence features of Drosha and Dicer cleavage sites affect the complexity of isomiRs

scientific article published on 10 April 2015

Sequence-non-specific effects generated by various types of RNA interference triggers

scientific article published on 22 November 2015

Sequence-non-specific effects of RNA interference triggers and microRNA regulators

scientific article

Silencing of genes responsible for polyQ diseases using chemically modified single-stranded siRNAs

scientific article published on 21 October 2016

Small RNA Detection by in Situ Hybridization Methods

scientific article

Small molecule kinase inhibitors alleviate different molecular features of myotonic dystrophy type 1.

scientific article published on 24 April 2014

Stress-induced changes in miRNA biogenesis and functioning

scientific article

Structural Characteristics of Simple RNA Repeats Associated with Disease and their Deleterious Protein Interactions

scientific article published on 11 April 2017

Structural aspects of microRNA biogenesis

scientific article published on February 2004

Structural basis of microRNA length variety.

scientific article

Structural diversity of triplet repeat RNAs

scientific article published on 16 February 2010

Structural factors determining DNA length limitations in conformation-sensitive mutation detection methods

scientific article published on 01 January 2005

Structural features of microRNA (miRNA) precursors and their relevance to miRNA biogenesis and small interfering RNA/short hairpin RNA design

scientific article

Structural insights into CUG repeats containing the 'stretched U-U wobble': implications for myotonic dystrophy

scientific article

Structure analysis of microRNA precursors

scientific article published on January 2006

Structures of trinucleotide repeats in human transcripts and their functional implications.

scientific article published on October 2003

The panorama of miRNA-mediated mechanisms in mammalian cells

scientific article

The role of Dicer protein partners in the processing of microRNA precursors

scientific article

The role of the immune system in triplet repeat expansion diseases

scientific article

The role of the precursor structure in the biogenesis of microRNA

scientific article

Trinucleotide repeat system for sequence specificity analysis of RNA structure probing reagents

scientific article published on 17 March 2010

Trinucleotide repeats in human genome and exome.

scientific article published on 09 March 2010

Trinucleotide repeats: triggers for genomic disorders?

scientific article published on 30 April 2010

Triplet repeat RNA structure and its role as pathogenic agent and therapeutic target

scientific article published on 9 September 2011

Triplet repeats in transcripts: structural insights into RNA toxicity

scientific article

miRNAmotif-A Tool for the Prediction of Pre-miRNA⁻Protein Interactions ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2018

qEva-CRISPR: a method for quantitative evaluation of CRISPR/Cas-mediated genome editing in target and off-target sites

scientific article published on 01 September 2018

siRNA release from pri-miRNA scaffolds is controlled by the sequence and structure of RNA.

scientific article published on 24 February 2016

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