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List of works by Ding-Shinn Chen

A Hospital-Based Study on the use of Alternative Medicine in Patients with Chronic Liver and Gastrointestinal Diseases

scientific article published on 01 January 2002

A Predisposition Toward Edwardsiella tarda Bacteremia in Individuals with Preexisting Liver Disease

scientific article published on 01 September 1995

A mass vaccination program in Taiwan against hepatitis B virus infection in infants of hepatitis B surface antigen-carrier mothers

scientific article published on May 1987

A pilot study of add-on oral hypoglycemic agents in treatment-naïve genotype-1 chronic hepatitis C patients receiving peginterferon alfa-2b plus ribavirin

scientific article published on 25 June 2014

A program for eradication of hepatitis B from Taiwan by a 10-year, four-dose vaccination program.

scientific article published on May 1996

ADAR2-mediated editing of miR-214 and miR-122 precursor and antisense RNA transcripts in liver cancers

scientific article

APRI-M6 for predicting long-term outcome of chronic hepatitis C patients after interferon-based therapy: More questions than answers

scientific article published on 01 June 2007

Absence or delayed appearance of hepatitis B core antibody in chronic hepatitis B surface antigen carrier children

scientific article published on 01 February 1993

Activation of protooncogene c-jun by the X protein of hepatitis B virus

scientific article published in January 1993

Acute rhabdomyolysis and chylous ascites in a patient with cirrhosis and malignant hepatic tumor

scientific article published on 22 May 2012

Adipocytokines and liver fibrosis stages in patients with chronic hepatitis B virus infection.

scientific article published on 12 March 2015

Age-related immune clearance of hepatitis B virus infection requires the establishment of gut microbiota

scientific article

Albumin messenger RNA is not specific for circulating hepatoma cells

scientific article published on 01 August 1994

Alcoholism, Hepatitis B and C Viral Infections, and Impaired Liver Function among Taiwanese Aboriginal Groups

scientific article published on 01 May 1996

Allelotype and loss of heterozygosity of p53 in primary and recurrent hepatocellular carcinomas. A study of 150 patients

scientific article published in January 1994

Amniocentesis in mothers who are hepatitis B virus carriers does not expose the infant to an increased risk of hepatitis B virus infection

scientific article published in January 1994

An ELISA for RNA helicase activity: application as an assay of the NS3 helicase of hepatitis C virus.

scientific article published in December 1998

An oath for bioscientists

scientific article

Androgen pathway stimulates MicroRNA-216a transcription to suppress the tumor suppressor in lung cancer-1 gene in early hepatocarcinogenesis

article

Applicability of staging systems for patients with hepatocellular carcinoma is dependent on treatment method – Analysis of 2010 Taiwanese patients

article

Association of HLA-DR14—DR52 with low responsiveness to hepatitis B vaccine in Chinese residents in Taiwan

article

Association of SCARB1 Gene Polymorphisms with Virological Response in Chronic Hepatitis C Patients Receiving Pegylated Interferon plus Ribavirin Therapy.

scientific article published on 26 August 2016

Association of chronic hepatitis B virus infection with insulin resistance and hepatic steatosis.

scientific article published on 19 November 2007

Association of pre-S deletion mutant of hepatitis B virus with risk of hepatocellular carcinoma

scientific article

Associations between hepatitis B virus genotype and mutants and the risk of hepatocellular carcinoma

scientific article published on 11 August 2008

Baseline seroepidemiology of hepatitis B virus infection in children in Taipei, 1984: a study just before mass hepatitis B vaccination program in Taiwan.

scientific article

Biologic and prognostic significance of hepatocyte hepatitis B core antigen expressions in the natural course of chronic hepatitis B virus infection

scientific article published in August 1987

Biologic significance of the detection of HBsAg and HBcAg in liver and tumor from 204 HBsAg-positive patients with primary hepatocellular carcinoma

scientific article

Biphasic pattern of depression and its predictors during pegylated interferon-based therapy in chronic hepatitis B and C patients.

scientific article published on 17 October 2012

Both insulin resistance and alanine aminotransferase level increase the risks of cardiovascular disease in fatty liver disease.

scientific article published in September 2009

Cancer prevention in Asia: resource-stratified guidelines from the Asian Oncology Summit 2013.

scientific article

Caput Medusae

scientific article published on 01 November 2005

Changes in ploidy distributions in human liver carcinogenesis

scientific article published in November 1988

Changing aetiologic patterns of acute viral hepatitis in Taiwanese children

Changing disease burden of hepatocellular carcinoma in the Far East and Southeast Asia.

scientific article

Changing seroepidemiology of hepatitis A virus infection in Taiwan

scientific article

Characterization of cytokeratin 19-positive hepatocyte foci in the regenerating rat liver after 2-AAF/CCl4 injury.

scientific article published on 28 July 2007

Characterization of hepatocyte growth factor expressed by baculovirus.

scientific article published on December 1993

Characterization of metastatic tumor antigen 1 and its interaction with hepatitis B virus X protein in NF-κB signaling and tumor progression in a woodchuck hepatocellular carcinoma model

scientific article published on 13 June 2016

Characterization of severe acute respiratory syndrome coronavirus genomes in Taiwan: molecular epidemiology and genome evolution

scholarly article

Childhood hepatocellular carcinoma develops exclusively in hepatitis B surface antigen carriers in three decades in Taiwan. Report of 51 cases strongly associated with rapid development of liver cirrhosis

scientific article

Chronic oral etoposide and tamoxifen in the treatment of far-advanced hepatocellular carcinoma

Clinical features, etiology, and survival of hepatocellular carcinoma among different countries

scientific article published on 01 February 2002

Clinical relevance of hepatitis B virus genotype in children with chronic infection and hepatocellular carcinoma

scientific article published in December 2004

Clinical significance and evolution of hepatic HBsAg expression in HBeAg-positive patients receiving interferon therapy

scientific article

Clinical significance of occult hepatitis B virus infection cannot be overlooked.

scientific article

Co-delivery of GM-CSF gene enhances the immune responses of hepatitis C viral core protein-expressing DNA vaccine: role of dendritic cells.

scientific article published on March 2002

Combining antiangiogenic therapy with immunotherapy exerts better therapeutical effects on large tumors in a woodchuck hepatoma model ⬇️

scientific article published on August 2, 2010

Comparative immunoproteomics of identification and characterization of virulence factors from Helicobacter pylori related to gastric cancer.

scientific article

Comparison of a 6-month course peginterferon alpha-2b plus ribavirin and interferon alpha-2b plus ribavirin in treating Chinese patients with chronic hepatitis C in Taiwan.

scientific article

Consolidation therapy for HBeAg-positive Asian chronic hepatitis B patients receiving lamivudine treatment: a multicentre study

scientific article published on 24 June 2013

Continuing Decrease in Hepatitis B Virus Infection 30 Years After Initiation of Infant Vaccination Program in Taiwan

scientific article published on 4 May 2016

Correlation of HBV DNA levels in serum and liver of chronic hepatitis B patients with cirrhosis

scientific article published on 01 April 2002

Correlation of hepatocyte HBsAg expression with virus replication and liver pathology

scientific article

Cytophotometric measurements of nuclear DNA content in hepatocellular carcinomas

scientific article published on 01 March 1987

Decreased incidence of hepatocellular carcinoma in hepatitis B vaccinees: a 20-year follow-up study.

scientific article published on 16 September 2009

Delta-agent infection in Taiwan

Depletion of β-catenin from mature hepatocytes of mice promotes expansion of hepatic progenitor cells and tumor development

scientific article published on 31 October 2011

Detection of Helicobacter pylori in gastric biopsy tissue by polymerase chain reaction

scientific article published on 01 May 1993

Detection of hepatitis B virus DNA by polymerase chain reaction in plasma of volunteer blood donors negative for hepatitis B surface antigen.

scientific article published on February 1991

Detection of replicative form of hepatitis C virus RNA in peripheral blood mononuclear cells.

scientific article published on November 1992

Determination of immune memory to hepatitis B vaccination through early booster response in college students

scientific article published in May 2010

Differences in hepatitis viral etiology of hepatocellular carcinoma in Taiwan and China

scientific article published on 10 December 2015

Distinct hepatitis B virus dynamics in the immunotolerant and early immunoclearance phases.

scientific article

Diverse virological, histopathological and prognostic implications of seroconversion from hepatitis B e antigen to anti-HBe in chronic hepatitis B virus infection

scientific article published in January 1986

Dual chronic hepatitis B virus and hepatitis C virus infection

scientific article published on 08 August 2009

Dynamics of hepatitis B e antigen index ratio correlate with treatment response in chronic hepatitis B patients

article

Early predictor of the efficacy of immunoprophylaxis against perinatal hepatitis B transmission: analysis of prophylaxis failure

scientific article published in June 1991

Efficacy of maternal tenofovir disoproxil fumarate in interrupting mother-to-infant transmission of hepatitis B virus

scientific article published on 7 April 2015

Epidemiologic features of Kawasaki disease in Taiwan, 1996-2002.

scientific article published in December 2004

Epidemiology of HBV infection in Asian blood donors: emphasis on occult HBV infection and the role of NAT.

scientific article published on May 2006

Expression and hypomethylation of alpha-fetoprotein gene in unicentric and multicentric human hepatocellular carcinomas

scientific article published on 01 January 1993

Fighting against viral hepatitis: lessons from Taiwan.

scientific article published in August 2011

From the big three to the big four

scientific article published on 17 May 2015

Fulminant hepatitis in children in Taiwan: the important role of hepatitis B virus.

scientific article

Fulminant hepatitis in infants in Taiwan: Strong association with hepatitis B e antigen-negative but antibody-positive maternal hepatitis B surface antigen carriage

Functional measurement of hepatitis C virus core-specific CD8(+) T-cell responses in the livers or peripheral blood of patients by using autologous peripheral blood mononuclear cells as targets or stimulators.

scientific article

GB virus C/hepatitis G virus infection in patients on continuous ambulatory peritoneal dialysis.

scientific article published on November 1998

Geographical distribution of the subtype of hepatitis b surface antigen in chinese ⬇️

scientific article published on January 1, 1977

Global control of hepatitis B virus infection.

scientific article

HBV genotypes and outcome of HBV infection.

scientific article published in January 2005

Hepatitis A vaccine in healthy adults: a comparison of immunogenicity and reactogenicity between two- and three-dose regimens

scientific article

Hepatitis B e antigen and antibody in asymptomatic Chinese with hepatitis B surface antigenemia in Taiwan

article

Hepatitis B post-partum e antigen clearance in hepatitis B carrier mothers: Correlation with viral characteristics

scientific article published on 01 March 2006

Hepatitis B vaccination in children: The Taiwan experience

scientific article published on 29 January 2010

Hepatitis B vaccination: The key towards elimination and eradication of hepatitis B

scientific article published on 03 February 2009

Hepatitis B vaccination: to boost or not to boost?

scientific article published in The Lancet

Hepatitis B viral genotypes and lamivudine resistance.

scientific article published in February 2002

Hepatitis B virus X protein enhances androgen receptor-responsive gene expression depending on androgen level

scholarly article

Hepatitis B virus basal core promoter mutation and DNA load correlate with expression of hepatitis B core antigen in patients with chronic hepatitis B.

scientific article published in March 2009

Hepatitis B virus infection, its sequelae, and prevention by vaccination ⬇️

scientific article published on January 21, 2011

Hepatitis B virus reactivation in patients receiving cancer chemotherapy: natural history, pathogenesis, and management

scientific article published on 14 June 2011

Hepatitis C Virus Infection in Pregnant Women: Detection by Different Anti-HCV Immunoassays and Serum HCV-RNA

article published in 2010

Hepatitis C virus RNA in saliva of patients with posttransfusion hepatitis and low efficiency of transmission among spouses ⬇️

scientific article published on January 1, 1992

Hepatitis C virus in a prospective study of posttransfusion non-A, non-B hepatitis in Taiwan.

scientific article published on October 1990

Hepatitis D virus infection in children with acute or chronic hepatitis B virus infection in Taiwan.

scientific article published in June 1988

Humoral and cellular immune responses to a hepatitis B vaccine booster 15-18 years after neonatal immunization

scientific article published in May 2008

Hypoxia-activated cytotoxic agent tirapazamine enhances hepatic artery ligation-induced killing of liver tumor in HBx transgenic mice

scientific article published on 04 October 2016

Icteric type hepatocellular carcinoma: Revisited 20 years later

scientific article published on 01 February 1998

Improved serodiagnosis of posttransfusion hepatitis C virus infection by a second-generation immunoassay based on multiple recombinant antigens

scientific article published on January 1, 1992

Incidence and clinical presentation of posttransfusion TT virus infection in prospectively followed transfusion recipients: emphasis on its relevance to hepatitis.

scientific article published in May 2000

Increased incidence of gastroesophageal reflux disease in patients with chronic hepatitis B virus infection ⬇️

scientific article published on July 1, 2010

Increased risk of cirrhosis and its decompensation in chronic hepatitis B patients with newly diagnosed diabetes: a nationwide cohort study

scientific article published on 18 September 2013

Increased risk of cirrhosis and its decompensation in chronic hepatitis C patients with new-onset diabetes: a nationwide cohort study

scientific article published on 17 July 2014

Increased risk of hepatocellular carcinoma in chronic hepatitis B patients with new onset diabetes: a nationwide cohort study.

scientific article published on 6 April 2015

Increased risk of hepatocellular carcinoma in chronic hepatitis C patients with new onset diabetes: a nation-wide cohort study.

scientific article published on 27 July 2015

Induction of liver alpha-1 acid glycoprotein gene expression involves both positive and negative transcription factors

scientific article published on January 1993

Inhibition of the membrane translocation and activation of protein kinase C, and potentiation of doxorubicin-induced apoptosis of hepatocellular carcinoma cells by tamoxifen ⬇️

scientific article published on February 15, 1998

Interferon-ribavirin for chronic hepatitis C with and without cirrhosis: analysis of individual patient data of six controlled trials. Eurohep Study Group for Viral Hepatitis.

scientific article

Kinetics of hepatitis B virus reactivation after chemotherapy: more questions than answers

scientific article published in November 2006

Laserthermia for the treatment of small hepatocellular carcinoma: a preliminary study.

scientific article

Least microtransfusion from mother to fetus in elective cesarean delivery.

scientific article published in February 1996

Local ablation vs. resection for the treatment of hepatocellular carcinoma

scientific article published on 01 February 2006

Long term immune response of universal hepatitis B vaccination in infancy: a community-based study in Taiwan.

scientific article published in May 1999

Long-term Effects of Hepatitis B Immunization of Infants in Preventing Liver Cancer

scientific article

Long-term immunogenicity and efficacy of universal hepatitis B virus vaccination in Taiwan.

scientific article published on 13 December 2002

Longitudinal change of HBsAg in HBeAg-negative patients with genotype B or C infection

scientific article

Low prevalence of hepatitis C virus infection among dentists in Taiwan ⬇️

scientific article published on May 1, 1993

Low-power laserthermia for the treatment of small hepatocellular carcinoma.

scientific article published in January 1991

Maternal Transmission of Hepatitis B Surface Antigen in Patients with Hepatocellular Carcinoma in Taiwan

article

Milder clinical manifestation of scrub typhus in Kinmen, Taiwan ⬇️

scientific article published on May 22, 2012

Minimal role of hepatitis C virus infection in childhood liver diseases in an area hyperendemic for hepatitis B infection.

scientific article published in August 1993

Minimization of hepatitis B infection by a 25-year universal vaccination program

article by Yen-Hsuan Ni et al published October 2012 in Journal of Hepatology

Mixed hepatitis B virus genotype infections: the more, the worse?

scientific article published in September 2006

Mother-to-infant transmission of hepatitis B virus infection: significance of maternal viral load and strategies for intervention

scientific article published on 26 February 2013

Multiple hepatocellular carcinomas at the early stage have different clonality

scientific article published in November 1993

Natural history of chronic hepatitis B virus infection: new light on an old story.

scientific article

No more excuses: viral hepatitis can be eliminated

scientific article published on April 2016

Non-A, non-B hepatitis in children: a clinical, histologic, and serologic study.

scientific article published on September 1991

Pediatric fulminant hepatic failure in endemic areas of hepatitis B infection: 15 years after universal hepatitis B vaccination

scientific article published in January 2004

Peginterferon alfa-2a plus ribavirin for the treatment of dual chronic infection with hepatitis B and C viruses

scientific article published on 29 October 2008

Peginterferon α in the treatment of chronic hepatitis B.

scientific article published on 16 April 2014

Pegylated IFN-α suppresses hepatitis C virus by promoting the DAPK-mTOR pathway.

scientific article published on 06 December 2016

Persistence of IgM hepatitis A antibody after clinical type A hepatitis

scientific article published on 01 July 1985

Plasma des-gamma-carboxyprothrombin in the early stage of hepatocellular carcinoma

scientific article (publication date: March 1990)

Posttransfusion hepatitis revisited by hepatitis C antibody assays and polymerase chain reaction

scientific article published on August 1, 1992

Prevalence of anti-HCV and HCV viremia in hemodialysis patients in Taiwan

scientific article published on June 1, 1992

Prevention of hepatitis B.

scientific article

Prevention of hepatocellular carcinoma by universal vaccination against hepatitis B virus: the effect and problems

scientific article

Prognostic Implications of Serum α-Fetoprotein Levels in Neonatal Hepatitis ⬇️

scientific article published on July 1, 1990

Prospects for hepatitis B virus eradication and control of hepatocellular carcinoma

article

Public health measures to control hepatitis B virus infection in the developing countries of the Asia-Pacific region

scientific article published in May 2000

Purification and characterization of nucleolin and its identification as a transcription repressor.

scientific article published on September 1994

Rapid growth of a hepatocellular carcinoma and the driving mutations revealed by cell-population genetic analysis of whole-genome data

scientific article

Recent advances in the research of hepatitis B virus-related hepatocellular carcinoma: epidemiologic and molecular biological aspects

scientific article published on January 2010

Recent updates in hepatitis vaccination and the prevention of hepatocellular carcinoma

scientific article

Recombinant immunoblot assay for hepatitis C antibody in patients with posttransfusion non-A, non-B hepatitis ⬇️

scientific article published on July 1, 1991

Reduced doses of hepatitis B immune globulin in the prevention of perinatal transmission of hepatitis B.

scientific article published in April 1987

Regression of Established Mouse Leukemia by GM-CSF-Transduced Tumor Vaccine: Implications for Cytotoxic T Lymphocyte Responses and Tumor Burdens ⬇️

scientific article published on November 1, 1997

Report from a Viral Hepatitis Policy Forum on implementing the WHO framework for global action on viral hepatitis in North Asia ⬇️

scientific article published on July 12, 2013

Ribavirin Enhances the Action of Interferon-α against Hepatitis C Virus by Promoting the p53 Activity through the ERK1/2 Pathway ⬇️

scientific article published on September 4, 2012

Ribavirin and interferon is effective for hepatitis C virus clearance in hepatitis B and C dually infected patients

scientific article published in March 2003

Ribavirin enhancement of hepatitis C virus core antigen-specific type 1 T helper cell response correlates with the increased IL-12 level

scientific article published in November 2000

Safety and immunogenicity of hepatitis A vaccine in healthy adult volunteers

scientific article published in July 1993

Searching for HLA-DRB1*1206 in volunteer marrow donors in four US population groups

scientific article published in November 2006

Secular trend of age-specific prevalence of hepatitis B surface and e antigenemia in pregnant women in Taiwan

scholarly article by Ho-Hsiung Lin published in February 2003

Seroepidemiologic survey for hepatitis B virus infection in Taiwan: the effect of hepatitis B mass immunization

scientific article published in February 1999

Seroprevalence of hepatitis B virus infection in children in Taipei, 1989: five years after a mass hepatitis B vaccination program

scientific article

Serum HBsAg, HBeAg, anti-HBe, and hepatitis B viral DNA in asymptomatic carriers in Taiwan

scientific article

Serum adiponectin correlates with viral characteristics but not histologic features in patients with chronic hepatitis C.

scientific article published in August 2005

Serum hepatitis B virus DNA in healthy HBsAg-negative Chinese adults evaluated by polymerase chain reaction

scientific article published in December 1990

Serum α-Fetoprotein Levels in Normal Infants

Somatic mutations at the trinucleotide repeats of androgen receptor gene in male hepatocellular carcinoma

scientific article

Somatosensory evoked potentials in subclinical portosystemic encephalopathy: a comparison with psychometric tests

scientific article

Sorafenib and its derivative SC-1 exhibit antifibrotic effects through signal transducer and activator of transcription 3 inhibition

scientific article published on 26 May 2015

Statements from the Taormina expert meeting on occult hepatitis B virus infection

scientific article published on 31 July 2008

Strategies to control hepatitis B: Public policy, epidemiology, vaccine and drugs

scientific article published on April 2015

Structure and Expression of Mouse α1-Acid Glycoprotein Gene-3 (AGP-3) ⬇️

scientific article published on May 1, 1992

Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase

scientific article

Surgical resection for recurrent hepatocellular carcinoma: prognosis and analysis of risk factors

scientific article published in July 1996

Systematic Review: Impact of Interferon-based Therapy on HCV-related Hepatocellular Carcinoma

scientific article published on 12 May 2015

Taiwan is on track of accelerating hepatitis C elimination by 2025

scientific article published on 22 February 2020

The conserved serine 177 in the delta antigen of hepatitis delta virus is one putative phosphorylation site and is required for efficient viral RNA replication

scientific article

Therapeutic implications of hepatitis B virus genotypes.

scientific article

Toward elimination and eradication of hepatitis B.

scientific article published on January 2010

Towards the eradication of hepatitis B in Taiwan

scientific article published on 16 December 2011

Transmission of occult hepatitis B virus by transfusion to adult and pediatric recipients in Taiwan

scientific article

Transplacental leakage of HBeAg-positive maternal blood as the most likely route in causing intrauterine infection with hepatitis B virus

scientific article published in December 1987

Tumor-induced immunosuppression: a barrier to immunotherapy of large tumors by cytokine-secreting tumor vaccine.

scientific article

Two decades of universal hepatitis B vaccination in taiwan: impact and implication for future strategies

scientific article published on 25 February 2007

Ultrasound-guided cutting biopsy for the diagnosis of hepatocellular carcinoma — a study based on 420 patients

scientific article published on 01 September 1996

Universal Hepatitis B Vaccination: Killing 2 Birds with 1 Stone

scientific article published on 01 December 2008

Universal hepatitis B vaccination and the decreased mortality from fulminant hepatitis in infants in Taiwan.

scientific article published in September 2001

Viremia profiles in children with chronic hepatitis B virus infection and spontaneous e antigen seroconversion

scientific article published on 11 April 2007

δ Agent Infection in Patients with Chronic Liver Diseases and Hepatocellular Carcinoma-An Infrequent Finding in Taiwan

scientific article published on 01 May 1984

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