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List of works by Karl Deisseroth

5-HT release in nucleus accumbens rescues social deficits in mouse autism model

scientific article published in Nature

A Brainstem-Spinal Cord Inhibitory Circuit for Mechanical Pain Modulation by GABA and Enkephalins

scientific article published on 31 January 2017

A Conversation with Karl Deisseroth

scientific article published in January 2014

A Genetically Defined Compartmentalized Striatal Direct Pathway for Negative Reinforcement

scientific article published on 10 September 2020

A Guide to Creating and Testing New INTRSECT Constructs.

scientific article published on 5 July 2017

A Look Inside the Brain

scientific article published in September 2016

A Molecular Calcium Integrator Reveals a Striatal Cell Type Driving Aversion

scientific article published on 04 December 2020

A Neural Circuit Mechanism for Encoding Aversive Stimuli in the Mesolimbic Dopamine System

scientific article published on 29 November 2018

A causal link between prediction errors, dopamine neurons and learning

scientific article

A coaxial optrode as multifunction write-read probe for optogenetic studies in non-human primates

scientific article published on 15 July 2013

A community-developed open-source computational ecosystem for big neuro data

A community-developed open-source computational ecosystem for big neuro data

article published in 2018

A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior.

scientific article

A fourth generation of neuroanatomical tracing techniques: exploiting the offspring of genetic engineering

scientific article

A hypothalamus-habenula circuit controls aversion

scientific article published on 12 February 2019

A major external source of cholinergic innervation of the striatum and nucleus accumbens originates in the brainstem

scientific article published on March 2014

A neuronal circuit for activating descending modulation of neuropathic pain

scientific article published on 09 September 2019

A new mode of corticothalamic transmission revealed in the Gria4(-/-) model of absence epilepsy

scientific article

A prefrontal cortex-brainstem neuronal projection that controls response to behavioural challenge

scientific article published in December 2012

A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.

scientific article published on 11 September 2017

A restriction fragment length polymorphism for human topoisomerase II: possible relationship to drug-resistance.

scientific article

A role for circuit homeostasis in adult neurogenesis

scientific article

A skin-inspired organic digital mechanoreceptor

scientific article published on October 2015

A unique population of ventral tegmental area neurons inhibits the lateral habenula to promote reward

scientific article

Activation of a novel p70 S6 kinase 1-dependent intracellular cascade in the basolateral nucleus of the amygdala is required for the acquisition of extinction memory

scientific article published on 2 May 2017

Activation of corticostriatal circuitry relieves chronic neuropathic pain.

scientific article

Activation of specific interneurons improves V1 feature selectivity and visual perception

scientific article

Active expiration induced by excitation of ventral medulla in adult anesthetized rats

scientific article

Activity in grafted human iPS cell-derived cortical neurons integrated in stroke-injured rat brain regulates motor behavior

scientific article published on 06 April 2020

Activity-dependent CREB phosphorylation: convergence of a fast, sensitive calmodulin kinase pathway and a slow, less sensitive mitogen-activated protein kinase pathway

scholarly article

Advanced CLARITY for rapid and high-resolution imaging of intact tissues

scientific article

All-Optical Interrogation of Neural Circuits

scientific article

Altered profile of basket cell afferent synapses in hyper-excitable dentate gyrus revealed by optogenetic and two-pathway stimulations.

scientific article published on 18 April 2012

Amygdala circuitry mediating reversible and bidirectional control of anxiety

scientific article

Amygdala-Midbrain Connections Modulate Appetitive and Aversive Learning

scientific article published on 02 April 2020

An Open Resource for Non-human Primate Optogenetics

scientific article published on 12 October 2020

An Ultra-Sensitive Step-Function Opsin for Minimally Invasive Optogenetic Stimulation in Mice and Macaques

scientific article published on 14 April 2020

An Ultra-Sensitive Step-Function Opsin for Minimally Invasive Optogenetic Stimulation in Mice and Macaques

scientific article published on 01 July 2020

An interactive framework for whole-brain maps at cellular resolution

scientific article published on 4 December 2017

An optical neural interface: in vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology

scientific article

An optogenetic toolbox designed for primates

scientific article

Ancestral Circuits for the Coordinated Modulation of Brain State

scientific article published on 31 October 2017

Antidepressant effect of optogenetic stimulation of the medial prefrontal cortex

scientific article

Approaches to optical neuromodulation from rodents to non-human primates by integrated optoelectronic devices

scientific article published in January 2011

Arc/Arg3.1 is a postsynaptic mediator of activity-dependent synapse elimination in the developing cerebellum.

scientific article published on June 2013

Astrocyte Intermediaries of Septal Cholinergic Modulation in the Hippocampus

scientific article published on 4 May 2016

Astrocytes control breathing through pH-dependent release of ATP

scientific article

Basal Forebrain Parvalbumin Neurons Mediate Arousals from Sleep Induced by Hypercarbia or Auditory Stimuli

scientific article published on 30 April 2020

Basolateral amygdala bidirectionally modulates stress-induced hippocampal learning and memory deficits through a p25/Cdk5-dependent pathway

scientific article published on 20 May 2015

Basomedial amygdala mediates top-down control of anxiety and fear

scientific article

Beyond the brain: Optogenetic control in the spinal cord and peripheral nervous system

scientific article published on May 2016

Bi-stable neural state switches

scientific article

Bidirectional Control of Generalized Epilepsy Networks via Rapid Real-Time Switching of Firing Mode

scientific article published on 14 December 2016

Brain circuit dynamics

scientific article

Brain-Derived Neurotrophic Factor in the Mesolimbic Reward Circuitry Mediates Nociception in Chronic Neuropathic Pain

scientific article published in March 2017

Brain-wide Electrical Spatiotemporal Dynamics Encode Depression Vulnerability

scientific article published in March 2018

CLARITY for mapping the nervous system ⬇️

scientific article published on June 1, 2013

CLARITY reveals dynamics of ovarian follicular architecture and vasculature in three-dimensions

scientific article

CREB phosphorylation and dephosphorylation: a Ca(2+)- and stimulus duration-dependent switch for hippocampal gene expression

scientific article

Ca2+-dependent regulation in neuronal gene expression

scientific article published on June 1997

CaV3.2 calcium channels control NMDA receptor-mediated transmission: a new mechanism for absence epilepsy

scientific article

Calmodulin priming: Nuclear translocation of a calmodulin complex and the memory of prior neuronal activity ⬇️

scientific article published on December 11, 2001

Calmodulin supports both inactivation and facilitation of L-type calcium channels

scientific article published in May 1999

Cardiogenic control of affective behavioural state

scientific article published on 01 March 2023

Causal interactions between fronto-parietal central executive and default-mode networks in humans

scientific article

Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward

scientific article

Cell type–specific channelrhodopsin-2 transgenic mice for optogenetic dissection of neural circuitry function

scientific article

Cerebellar Purkinje cell activity drives motor learning

scientific article

Cerebellar nuclei evolved by repeatedly duplicating a conserved cell-type set

scientific article published on 01 December 2020

Challenges and Opportunities for Next-Generation Intracortically Based Neural Prostheses ⬇️

scientific article published on January 20, 2011

Channelrhodopsin-2 and optical control of excitable cells

scientific article

Cholinergic Interneurons Control Local Circuit Activity and Cocaine Conditioning ⬇️

scientific article published on December 17, 2010

Chronic optogenetic activation augments aβ pathology in a mouse model of Alzheimer disease

scientific article

Circuit dynamics of adaptive and maladaptive behaviour

scientific article

Circuit-breakers: optical technologies for probing neural signals and systems

scientific article

Closed-loop and activity-guided optogenetic control

scientific article

Cognitive neuroscience: In search of lost time

scientific article published in February 2017

Color-tuned channelrhodopsins for multiwavelength optogenetics ⬇️

scientific article published on July 27, 2012

Communication in Neural Circuits: Tools, Opportunities, and Challenges

scientific article

Comparison of diffusion MRI and CLARITY fiber orientation estimates in both gray and white matter regions of human and primate brain

scientific article published on 29 December 2020

Competition between engrams influences fear memory formation and recall.

scientific article published in July 2016

Comprehensive Dual- and Triple-Feature Intersectional Single-Vector Delivery of Diverse Functional Payloads to Cells of Behaving Mammals

scientific article published on 20 June 2020

Controlling neuronal activity

scientific article

Controlling the Brain with Light

scientific article published on November 1, 2010

Coordinated Reductions in Excitatory Input to the Nucleus Accumbens Underlie Food Consumption

scientific article published on 23 August 2018

Coordination of Brain-Wide Activity Dynamics by Dopaminergic Neurons

scientific article

Corrigendum: Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression

scientific article published on 17 June 2015

Cortical Observation by Synchronous Multifocal Optical Sampling Reveals Widespread Population Encoding of Actions

scientific article published on 14 May 2020

Cortical and Subcortical Contributions to Short-Term Memory for Orienting Movements.

scientific article published on 30 September 2015

Cortical layer-specific critical dynamics triggering perception

scientific article published on 18 July 2019

Cortically projecting basal forebrain parvalbumin neurons regulate cortical gamma band oscillations

scientific article

Critical dependence of cAMP response element-binding protein phosphorylation on L-type calcium channels supports a selective response to EPSPs in preference to action potentials.

scientific article published on January 2000

Cross-resistance of an amsacrine-resistant human leukemia line to topoisomerase II reactive DNA intercalating agents. Evidence for two topoisomerase II directed drug actions ⬇️

scientific article published on April 23, 1991

Crystal structure of the channelrhodopsin light-gated cation channel

scientific article

Crystal structure of the natural anion-conducting channelrhodopsin GtACR1

scientific article published in Nature

Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice

scientific article

Daytime spikes in dopaminergic activity drive rapid mood-cycling in mice.

scientific article published on 17 February 2015

Deep brain optogenetics without intracranial surgery

scientific article published on 05 October 2020

Deep posteromedial cortical rhythm in dissociation

scientific article published on 16 September 2020

Dendritic calcium signals in rhesus macaque motor cortex drive an optical brain-computer interface

scientific article

Dendritic inhibition provided by interneuron-specific cells controls the firing rate and timing of the hippocampal feedback inhibitory circuitry.

scientific article published in March 2014

Depression: the best way forward

scientific article published in November 2014

Designer receptors show role for ventral pallidum input to ventral tegmental area in cocaine seeking

scientific article published on 02 March 2014

Development of an optogenetic toolkit for neural circuit dissection in squirrel monkeys.

scientific article

Developmental Dysfunction of VIP Interneurons Impairs Cortical Circuits

scientific article

Differential modulation of excitatory and inhibitory striatal synaptic transmission by histamine.

scientific article

Direct excitation of parvalbumin-positive interneurons by M1 muscarinic acetylcholine receptors: roles in cellular excitability, inhibitory transmission and cognition

scientific article published on 30 May 2014

Distinct Signaling by Ventral Tegmental Area Glutamate, GABA, and Combinatorial Glutamate-GABA Neurons in Motivated Behavior

scientific article published on 01 September 2020

Distinct Thalamic Reticular Cell Types Differentially Modulate Normal and Pathological Cortical Rhythms

scientific article published on June 2017

Diverging neural pathways assemble a behavioural state from separable features in anxiety.

scientific article published on 20 March 2013

Dlx5 and Dlx6 regulate the development of parvalbumin-expressing cortical interneurons

scientific article

Dopamine Modulation of Prefrontal Cortex Activity Is Manifold and Operates at Multiple Temporal and Spatial Scales

scientific article published on 01 April 2019

Dopamine neurons modulate neural encoding and expression of depression-related behaviour

scientific article

Dopaminergic Dynamics Contributing to Social Behavior

scientific article published on January 2014

Dopaminergic dynamics underlying sex-specific cocaine reward

scientific article published on 10 January 2017

Driving fast-spiking cells induces gamma rhythm and controls sensory responses

scientific article

Drug-driven AMPA receptor redistribution mimicked by selective dopamine neuron stimulation

scientific article

Dynamic changes in neural circuitry during adolescence are associated with persistent attenuation of fear memories

scientific article

Dynamic multiphosphorylation passwords for activity-dependent gene expression

scientific article published in April 2002

Dynamics of retrieval strategies for remote memories

scientific article published on 20 October 2011

Dysregulation of Prefrontal Cortex-Mediated Slow-Evolving Limbic Dynamics Drives Stress-Induced Emotional Pathology

scientific article published on 21 June 2016

Encoding of conditioned fear in central amygdala inhibitory circuits

scientific article published on November 2010

Endocannabinoid Modulation of Orbitostriatal Circuits Gates Habit Formation

scientific article

Engineering approaches to illuminating brain structure and dynamics

scientific article

Enhancing the performance of the light field microscope using wavefront coding

scientific article

Escape behavior elicited by single, channelrhodopsin-2-evoked spikes in zebrafish somatosensory neurons

scientific article

Establishing a fiber-optic-based optical neural interface

scientific article published on August 2014

Excitation of Diverse Classes of Cholecystokinin Interneurons in the Basal Amygdala Facilitates Fear Extinction

scientific article published on 07 November 2019

Excitation-neurogenesis coupling in adult neural stem/progenitor cells

scientific article

Excitatory synapses and gap junctions cooperate to improve Pv neuronal burst firing and cortical social cognition in Shank2-mutant mice

scientific article

Excitatory transmission at thalamo-striatal synapses mediates susceptibility to social stress

scientific article published on June 2015

Excitatory transmission from the amygdala to nucleus accumbens facilitates reward seeking

scientific article

Expanding the repertoire of optogenetically targeted cells with an enhanced gene expression system

scientific article

Experience-independent transformation of single-cell 3D genome structure and transcriptome during postnatal development of the mammalian brain

scientific article

Extended field-of-view and increased-signal 3D holographic illumination with time-division multiplexing

scientific article published in December 2015

Fast near-whole-brain imaging in adult Drosophila during responses to stimuli and behavior

article

Form Meets Function in the Brain: Observing the Activity and Structure of Specific Neural Connections

Frequency-dependent, cell type-divergent signaling in the hippocamposeptal projection.

scientific article

Functional Control of Transplantable Human ESC-Derived Neurons Via Optogenetic Targeting ⬇️

scientific article published on November 1, 2010

Functional integration of grafted neural stem cell-derived dopaminergic neurons monitored by optogenetics in an in vitro Parkinson model

scientific article

Functional maturation of human neural stem cells in a 3D bioengineered brain model enriched with fetal brain-derived matrix

scientific article published on 29 November 2019

GABA excitation in the adult brain: a mechanism for excitation- neurogenesis coupling.

scientific article

GABA neurons of the VTA drive conditioned place aversion.

scientific article published on 21 March 2012

GABAergic circuits mediate the reinforcement-related signals of striatal cholinergic interneurons

scientific article

GABAergic projection neurons route selective olfactory inputs to specific higher-order neurons

scientific article

Gamma oscillations organize top-down signalling to hypothalamus and enable food seeking

scientific article published in February 2017

Gating of social reward by oxytocin in the ventral tegmental area.

scientific article published on 28 September 2017

Genetic dissection of an amygdala microcircuit that gates conditioned fear

scientific article

Genetic reactivation of cone photoreceptors restores visual responses in retinitis pigmentosa

scientific article

Genetically encoded voltage sensor goes live

scientific article published in November 2013

Genetically identified amygdala-striatal circuits for valence-specific behaviors

scientific article published on 18 October 2021

Genetically targeted chemical assembly of functional materials in living cells, tissues, and animals

scientific article published on 19 March 2020

Genetically targeted chemical assembly of polymers specifically localized extracellularly to surface membranes of living neurons

scientific article published on 09 August 2023

Global Representations of Goal-Directed Behavior in Distinct Cell Types of Mouse Neocortex

scientific article published in May 2017

Global and local fMRI signals driven by neurons defined optogenetically by type and wiring

scientific article

Glutamatergic Neurotransmission between the C1 Neurons and the Parasympathetic Preganglionic Neurons of the Dorsal Motor Nucleus of the Vagus ⬇️

scientific article published on January 23, 2013

Glutamatergic signaling by mesolimbic dopamine neurons in the nucleus accumbens

scientific article

Hebbian and neuromodulatory mechanisms interact to trigger associative memory formation

scientific article

Hemisphere-specific optogenetic stimulation reveals left-right asymmetry of hippocampal plasticity ⬇️

scientific article published on September 25, 2011

Hierarchical neural architecture underlying thirst regulation

scientific article

High-efficiency channelrhodopsins for fast neuronal stimulation at low light levels

scientific article

High-frequency hippocampal oscillations activated by optogenetic stimulation of transplanted human ESC-derived neurons

scientific article

High-speed imaging reveals neurophysiological links to behavior in an animal model of depression

scientific article

High-speed interferometric imaging reveals dynamics of neuronal deformation during the action potential

scientific article published on 27 April 2020

High-speed mapping of synaptic connectivity using photostimulation in Channelrhodopsin-2 transgenic mice

scientific article

Hilar somatostatin interneuron loss reduces dentate gyrus inhibition in a mouse model of temporal lobe epilepsy

scientific article published on 31 March 2016

Hippocampal "cholinergic interneurons" visualized with the choline acetyltransferase promoter: anatomical distribution, intrinsic membrane properties, neurochemical characteristics, and capacity for cholinergic modulation

scientific article

Human pluripotent stem cell tools for cardiac optogenetics

scientific article

Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer

scientific article

Hydrogel-Tissue Chemistry: Principles and Applications

scientific article published on 01 May 2018

Hypothalamic control of male aggression-seeking behavior

scientific article

Hypothalamic neurotensin projections promote reward by enhancing glutamate transmission in the VTA.

scientific article published on May 2013

Identification of a point mutation in the topoisomerase II gene from a human leukemia cell line containing an amsacrine-resistant form of topoisomerase II ⬇️

scientific article (publication date: September 1991)

Illuminating circuitry relevant to psychiatric disorders with optogenetics

scientific article

Illuminating next-generation brain therapies

scientific article published on 18 January 2016

Improved expression of halorhodopsin for light-induced silencing of neuronal activity

scientific article

In Vivo Fiber Photometry Reveals Signature of Future Stress Susceptibility in Nucleus Accumbens

scientific article published on 07 June 2017

In vivo imaging identifies temporal signature of D1 and D2 medium spiny neurons in cocaine reward

scientific article

In vivo light-induced activation of neural circuitry in transgenic mice expressing channelrhodopsin-2.

scientific article

In vivo optogenetic stimulation of neocortical excitatory neurons drives brain-state-dependent inhibition

scientific article

Induced chromosome deletions cause hypersociability and other features of Williams-Beuren syndrome in mice

scientific article

Input-specific control of reward and aversion in the ventral tegmental area

scientific article

Intact-Brain Analyses Reveal Distinct Information Carried by SNc Dopamine Subcircuits

scientific article published on July 2015

Integrated device for combined optical neuromodulation and electrical recording for chronic in vivo applications

scientific article

Integrated device for optical stimulation and spatiotemporal electrical recording of neural activity in light-sensitized brain tissue

scientific article

Integration of light-controlled neuronal firing and fast circuit imaging.

scientific article

Interacting neural ensembles in orbitofrontal cortex for social and feeding behaviour

Investigating the feasibility of channelrhodopsin variants for nanoscale optogenetics

scientific article published on 01 January 2019

In Vivo Interrogation of Spinal Mechanosensory Circuits

scientific article published on November 2016

L-type calcium channels and GSK-3 regulate the activity of NF-ATc4 in hippocampal neurons

scientific article published on October 1999

LSPS/Optogenetics to Improve Synaptic Connectivity Mapping: Unmasking the Role of Basket Cell-Mediated Feedforward Inhibition

scientific article

Lee et al. reply

scientific article published in Nature

Left-right dissociation of hippocampal memory processes in mice

scientific article

Leptin regulates the reward value of nutrient

scientific article

Lifelong restructuring of 3D genome architecture in cerebellar granule cells

scientific article published on 07 September 2023

Light microscopy mapping of connections in the intact brain

scientific article

Locus coeruleus and dopaminergic consolidation of everyday memory

scientific article published on 07 September 2016

Long-Range GABAergic Inputs Regulate Neural Stem Cell Quiescence and Control Adult Hippocampal Neurogenesis

scientific article published in November 2017

Making waves: initiation and propagation of corticothalamic Ca2+ waves in vivo

scientific article published in March 2013

Manipulating a "cocaine engram" in mice.

scientific article

Manipulation of an innate escape response in Drosophila: photoexcitation of acj6 neurons induces the escape response

scientific article

Mapping Anatomy to Behavior in Thy1:18 ChR2-YFP Transgenic Mice Using Optogenetics

scientific article published in June 2015

Mapping Brain-Wide Afferent Inputs of Parvalbumin-Expressing GABAergic Neurons in Barrel Cortex Reveals Local and Long-Range Circuit Motifs

scientific article published on 01 September 2019

Mapping projections of molecularly defined dopamine neuron subtypes using intersectional genetic approaches

scientific article published on 13 August 2018

Medial prefrontal D1 dopamine neurons control food intake

scientific article

Mesolimbic dopamine dynamically tracks, and is causally linked to, discrete aspects of value-based decision making

scientific article published on 13 November 2014

Midbrain circuits for defensive behaviour

scientific article

Millisecond-timescale, genetically targeted optical control of neural activity

scientific article (publication date: September 2005)

Modular organization of the brainstem noradrenaline system coordinates opposing learning states.

scientific article published on 18 September 2017

Modulation of prefrontal cortex excitation/inhibition balance rescues social behavior in CNTNAP2-deficient mice.

scientific article published in August 2017

Molecular Dynamics of Channelrhodopsin at the Early Stages of Channel Opening

scientific article published on 26 June 2015

Molecular and Cellular Mechanisms for Trapping and Activating Emotional Memories

scientific article

Molecular and Circuit-Dynamical Identification of Top-Down Neural Mechanisms for Restraint of Reward Seeking

scientific article

Molecular and cellular approaches for diversifying and extending optogenetics

scientific article

Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes

scientific article

Multimodal characterization of the human nucleus accumbens

scientific article published on 08 May 2019

Multimodal fast optical interrogation of neural circuitry

scientific article

Multimodal image registration and connectivity analysis for integration of connectomic data from microscopy to MRI

scientific article published on 03 December 2019

Multiple convergent hypothalamus-brainstem circuits drive defensive behavior

scientific article published on 22 June 2020

Multiple sources of striatal inhibition are differentially affected in Huntington's disease mouse models

scientific article published on April 2013

Multiplexed Intact-Tissue Transcriptional Analysis at Cellular Resolution

scientific article published on February 2016

Multiregion neuronal activity: the forest and the trees

scientific article published on 3 October 2022

Multiscale computational models for optogenetic control of cardiac function

scientific article

Muscarinic excitation of parvalbumin-positive interneurons contributes to the severity of pilocarpine-induced seizures

scientific article

Nanotools for neuroscience and brain activity mapping

scientific article published on 20 March 2013

Natural neural projection dynamics underlying social behavior

scientific article

Neocortical excitation/inhibition balance in information processing and social dysfunction ⬇️

scientific article (publication date: 27 July 2011)

Network-level effects of optogenetic stimulation in a computer model of macaque primary motor cortex.

scientific article published on 21 July 2014

Neural correlates of ingroup bias for prosociality in rats

scientific article

Neural signatures of sleep in zebrafish

scientific article published on 10 July 2019

Neural substrates of awakening probed with optogenetic control of hypocretin neurons

scientific article (publication date: 15 November 2007)

Neuronal Dynamics Regulating Brain and Behavioral State Transitions

scientific article published on 25 April 2019

Neuronal activity regulates neurotransmitter switching in the adult brain following light-induced stress

scientific article published on 23 April 2018

Neuronal calcium-binding proteins 1/2 localize to dorsal root ganglia and excitatory spinal neurons and are regulated by nerve injury

scientific article

Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision

scientific article

Neuronal filtering of multiplexed odour representations ⬇️

scientific article published on November 13, 2011

Neuroscience. The brain activity map

scientific article published on 07 March 2013

Next-generation optical technologies for illuminating genetically targeted brain circuits

scientific article

Next-generation probes, particles, and proteins for neural interfacing

scientific article

Next-generation transgenic mice for optogenetic analysis of neural circuits

scientific article

Nociceptive neurons protect Drosophila larvae from parasitoid wasps

scientific article

Nucleus accumbens D2R cells signal prior outcomes and control risky decision-making

scientific article published on 23 March 2016

Nucleus accumbens-specific interventions in RGS9-2 activity modulate responses to morphine

scientific article published on 24 February 2014

OPTOGENETICS. Expanding the optogenetics toolkit

scientific article published on August 2015

Optetrode: a multichannel readout for optogenetic control in freely moving mice

scientific article

Optical activation of lateral amygdala pyramidal cells instructs associative fear learning

scientific article

Optical and chemical discoveries recognized for impact on biology and psychiatry

scientific article

Optical control of neuronal excitation and inhibition using a single opsin protein, ChR2.

scientific article

Optical deconstruction of parkinsonian neural circuitry

scientific article (publication date: 17 April 2009)

Optical inhibition of motor nerve and muscle activity in vivo

scientific article published on 30 April 2013

Optical neural interfaces

scientific article

Optical suppression of drug-evoked phasic dopamine release

scientific article

Optimization of CLARITY for Clearing Whole-Brain and Other Intact Organs(1,2,3)

scientific article

Optogenetic Dissection of Neuronal Circuits in Zebrafish using Viral Gene Transfer and the Tet System

scientific article published on 11 December 2009

Optogenetic Stimulation of Neural Grafts Enhances Neurotransmission and Downregulates the Inflammatory Response in Experimental Stroke Model

scientific article

Optogenetic activation of an inhibitory network enhances feedforward functional connectivity in auditory cortex

scientific article

Optogenetic and chemogenetic strategies for sustained inhibition of pain

scientific article published on 03 August 2016

Optogenetic and potassium channel gene therapy in a rodent model of focal neocortical epilepsy

scientific article

Optogenetic approaches addressing extracellular modulation of neural excitability

scientific article published on 5 April 2016

Optogenetic control of epileptiform activity

scientific article

Optogenetic control of targeted peripheral axons in freely moving animals

scientific article

Optogenetic delay of status epilepticus onset in an in vivo rodent epilepsy model

scientific article

Optogenetic inhibition of chemically induced hypersynchronized bursting in mice

scientific article published on 31 January 2014

Optogenetic inhibition of cocaine seeking in rats

scientific article

Optogenetic inhibition of dorsal medial prefrontal cortex attenuates stress-induced reinstatement of palatable food seeking in female rats

scientific article published on January 2013

Optogenetic interrogation of dopaminergic modulation of the multiple phases of reward-seeking behavior

scientific article

Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures

scientific article

Optogenetic investigation of neural circuits underlying brain disease in animal models ⬇️

scientific article published on March 20, 2012

Optogenetic manipulation of an ascending arousal system tunes cortical broadband gamma power and reveals functional deficits relevant to schizophrenia

scientific article published on 20 July 2020

Optogenetic neuronal stimulation promotes functional recovery after stroke

scientific article

Optogenetic stimulation of a hippocampal engram activates fear memory recall ⬇️

scientific article published on March 22, 2012

Optogenetic stimulation of cholinergic brainstem neurons during focal limbic seizures: Effects on cortical physiology

scientific article

Optogenetics

scientific article published on 20 December 2010

Optogenetics

scientific article published on 01 October 2013

Optogenetics and psychiatry: applications, challenges, and opportunities

scientific article published on 13 April 2012

Optogenetics and the circuit dynamics of psychiatric disease

scientific article published on May 2015

Optogenetics enables functional analysis of human embryonic stem cell-derived grafts in a Parkinson's disease model

scientific article

Optogenetics in Freely Moving Mammals: Dopamine and Reward

scientific article published on 3 August 2015

Optogenetics in neural systems

scientific article (publication date: 14 July 2011)

Optogenetics reveal delayed afferent synaptogenesis on grafted human-induced pluripotent stem cell-derived neural progenitors

scientific article published in December 2014

Optogenetics: 10 years of microbial opsins in neuroscience

scientific article

Optogenetics: background and concepts for neurosurgery

scientific article published in July 2011

Optogenetics: opsins and optical interfaces in neuroscience

scientific article published in August 2014

Orderly recruitment of motor units under optical control in vivo

scientific article

Parvalbumin neurons and gamma rhythms enhance cortical circuit performance

scientific article (publication date: 4 June 2009)

Pathways to clinical CLARITY: volumetric analysis of irregular, soft, and heterogeneous tissues in development and disease

scientific article

Patterned photostimulation via visible-wavelength photonic probes for deep brain optogenetics

scientific article published on 6 December 2016

Phasic Dopamine Signals in the Nucleus Accumbens that Cause Active Avoidance Require Endocannabinoid Mobilization in the Midbrain

scientific article published on 16 April 2018

Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning

scientific article (publication date: 22 May 2009)

Phototactic guidance of a tissue-engineered soft-robotic ray.

scientific article

Photothermal Genetic Engineering ⬇️

scientific article published on September 6, 2012

Place field assembly distribution encodes preferred locations

scientific article published on 12 September 2017

Pontomesencephalic Tegmental Afferents to VTA Non-dopamine Neurons Are Necessary for Appetitive Pavlovian Learning

scientific article published on 25 August 2016

Positive reinforcement mediated by midbrain dopamine neurons requires D1 and D2 receptor activation in the nucleus accumbens

scientific article

Posttraining optogenetic manipulations of basolateral amygdala activity modulate consolidation of inhibitory avoidance memory in rats

scientific article published on 11 February 2013

Prefrontal D1 dopamine signaling is required for temporal control ⬇️

scientific article published on November 26, 2012

Prefrontal Parvalbumin Neurons in Control of Attention

scientific article

Prefrontal cortex neuronal ensembles encoding fear drive fear expression during long-term memory retrieval

scientific article published on 24 July 2019

Prefrontal cortical regulation of brainwide circuit dynamics and reward-related behavior

scientific article published on January 2016

Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsins

scientific article

Proceedings of the Eighth Annual Deep Brain Stimulation Think Tank: Advances in Optogenetics, Ethical Issues Affecting DBS Research, Neuromodulatory Approaches for Depression, Adaptive Neurostimulation, and Emerging DBS Technologies

scientific article

Projections from neocortex mediate top-down control of memory retrieval

scientific article

Publisher Correction: An interactive framework for whole-brain maps at cellular resolution

scientific article published on 18 December 2017

Publisher Correction: Development of an optogenetic toolkit for neural circuit dissection in squirrel monkeys

scientific article published on 05 December 2019

Publisher Correction: Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity

scientific article published on 01 January 2018

Quantitative validation of immunofluorescence and lectin staining using reduced CLARITY acrylamide formulations

scientific article published on 14 December 2017

Rabies screen reveals GPe control of cocaine-triggered plasticity

scientific article published on 13 September 2017

Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons

scientific article

Rational Engineering of XCaMPs, a Multicolor GECI Suite for In Vivo Imaging of Complex Brain Circuit Dynamics

scientific article published on 09 May 2019

Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri

scientific article

Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry

scientific article

Repeated Cortico-Striatal Stimulation Generates Persistent OCD-Like Behavior ⬇️

scientific article published on June 7, 2013

Retrograde endocannabinoid signaling at inhibitory synapses in vivo

scientific article published on 29 February 2024

Reversible online control of habitual behavior by optogenetic perturbation of medial prefrontal cortex

scientific article

Reversible temporally-specific inhibition of muscle using a light-activated chloride channel

SNCA triplication Parkinson's patient's iPSC-derived DA neurons accumulate α-synuclein and are susceptible to oxidative stress

scientific article

SPED Light Sheet Microscopy: Fast Mapping of Biological System Structure and Function

scientific article

Scale-Invariant Visual Capabilities Explained by Topographic Representations of Luminance and Texture in Primate V1

scientific article published on 01 November 2018

Scale-Invariant Visual Capabilities Explained by Topographic Representations of Luminance and Texture in Primate V1.

scientific article published in December 2018

Segregated cholinergic transmission modulates dopamine neurons integrated in distinct functional circuits

scientific article published on 27 June 2016

Septohippocampal transmission from parvalbumin-positive neurons features rapid recovery from synaptic depression

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Serotonin engages an anxiety and fear-promoting circuit in the extended amygdala

scientific article published on 24 August 2016

Signaling from synapse to nucleus: postsynaptic CREB phosphorylation during multiple forms of hippocampal synaptic plasticity

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Signaling from synapse to nucleus: the logic behind the mechanisms

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Simultaneous cellular-resolution optical perturbation and imaging of place cell firing fields

scientific article published on 17 November 2014

Simultaneous fast measurement of circuit dynamics at multiple sites across the mammalian brain

scientific article published on 15 February 2016

Sleep homeostasis modulates hypocretin-mediated sleep-to-wake transitions

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Spaced stimuli stabilize MAPK pathway activation and its effects on dendritic morphology.

scientific article published in February 2001

Special issue on optical neural engineering: advances in optical stimulation technology

scientific article published on 19 July 2010

Stretchable and Fully Degradable Semiconductors for Transient Electronics

scientific article published on 13 November 2019

Striatal Cholinergic Interneurons Control Motor Behavior and Basal Ganglia Function in Experimental Parkinsonism

scientific article published on 14 October 2015

Striatal dopamine release is triggered by synchronized activity in cholinergic interneurons

scientific article published in July 2012

Striosomes Mediate Value-Based Learning Vulnerable in Age and a Huntington's Disease Model

scientific article published on 21 October 2020

Structural and molecular interrogation of intact biological systems

scientific article (publication date: 16 May 2013)

Structural foundations of optogenetics: Determinants of channelrhodopsin ion selectivity

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Structural mechanisms of selectivity and gating in anion channelrhodopsins

scientific article published in Nature

Structural model of channelrhodopsin

scientific article published on 11 January 2012

Structure-guided transformation of channelrhodopsin into a light-activated chloride channel

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Sustained Attentional States Require Distinct Temporal Involvement of the Dorsal and Ventral Medial Prefrontal Cortex

scientific article published on 31 August 2016

Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation

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Synaptic activity unmasks dopamine D2 receptor modulation of a specific class of layer V pyramidal neurons in prefrontal cortex ⬇️

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Synaptic encoding of fear extinction in mPFC-amygdala circuits

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Synaptic plasticity: A molecular mechanism for metaplasticity

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Targeted optogenetic stimulation and recording of neurons in vivo using cell-type-specific expression of Channelrhodopsin-2.

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Targeting Neural Circuits

scientific article published on April 2016

Targeting and readout strategies for fast optical neural control in vitro and in vivo

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Targeting cells with single vectors using multiple-feature Boolean logic

scientific article (publication date: July 2014)

Temporally precise in vivo control of intracellular signalling

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Thalamic Reticular Nucleus Parvalbumin Neurons Regulate Sleep Spindles and Electrophysiological Aspects of Schizophrenia in Mice

scientific article published on 05 March 2019

Thalamic control of sensory selection in divided attention

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The BRAIN Initiative: developing technology to catalyse neuroscience discovery

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The Open Connectome Project Data Cluster: Scalable Analysis and Vision for High-Throughput Neuroscience

scientific article (publication date: 2013)

The central amygdala controls learning in the lateral amygdala

scientific article published on 23 October 2017

The contribution of raised intraneuronal chloride to epileptic network activity

scientific article published on May 2015

The development and application of optogenetics

scientific article (publication date: 2011)

The form and function of channelrhodopsin

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The microbial opsin family of optogenetic tools

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The need for calcium imaging in nonhuman primates: New motor neuroscience and brain-machine interfaces

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The separate effects of lipids and proteins on brain MRI contrast revealed through tissue clearing

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Thirst regulates motivated behavior through modulation of brainwide neural population dynamics.

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Thirst-associated preoptic neurons encode an aversive motivational drive.

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Three-dimensional intact-tissue sequencing of single-cell transcriptional states

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Tracking Stem Cell Differentiation in the Setting of Automated Optogenetic Stimulation ⬇️

scientific article published on January 1, 2011

Translocation of calmodulin to the nucleus supports CREB phosphorylation in hippocampal neurons ⬇️

scientific article published on March 12, 1998

Tuning arousal with optogenetic modulation of locus coeruleus neurons

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Two eARCHT3.0 Lines for Optogenetic Silencing of Dopaminergic and Serotonergic Neurons

scientific article published on 01 February 2019

Two genetically, anatomically and functionally distinct cell types segregate across anteroposterior axis of paraventricular thalamus

scientific article published on 13 January 2020

Two-photon optogenetic toolbox for fast inhibition, excitation and bistable modulation

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Two-photon optogenetics of dendritic spines and neural circuits

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Ultrafast optogenetic control.

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Uneven balance of power between hypothalamic peptidergic neurons in the control of feeding

article published in the Proceedings of the National Academy of Sciences of the United States of America

Vasopressin excites interneurons to suppress hippocampal network activity across a broad span of brain maturity at birth

scientific article published on 28 November 2017

Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression

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Ventromedial prefrontal cortex pyramidal cells have a temporal dynamic role in recall and extinction of cocaine-associated memory

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Virally mediated optogenetic excitation and inhibition of pain in freely moving nontransgenic mice

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Visualizing hypothalamic network dynamics for appetitive and consummatory behaviors

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Wave optics theory and 3-D deconvolution for the light field microscope

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When the electricity (and the lights) go out: transient changes in excitability ⬇️

scientific article published on July 26, 2012

Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity

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Wirelessly powered, fully internal optogenetics for brain, spinal and peripheral circuits in mice

scientific article published on 17 August 2015

Wiring and Molecular Features of Prefrontal Ensembles Representing Distinct Experiences

scientific article published on 25 May 2016

eNpHR: a Natronomonas halorhodopsin enhanced for optogenetic applications

scientific article

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