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List of works by Gene P. Siegal

A Phase I Study of a Tropism-Modified Conditionally Replicative Adenovirus for Recurrent Malignant Gynecologic Diseases ⬇️

scientific article published on October 26, 2010

A canine conditionally replicating adenovirus for evaluating oncolytic virotherapy in a syngeneic animal model

scientific article published in February 2003

A fiber-modified mesothelin promoter-based conditionally replicating adenovirus for treatment of ovarian cancer

scientific article

A fiber-modified, secretory leukoprotease inhibitor promoter-based conditionally replicating adenovirus for treatment of ovarian cancer.

scientific article published on February 2005

A mosaic fiber adenovirus serotype 5 vector containing reovirus sigma 1 and adenovirus serotype 3 knob fibers increases transduction in an ovarian cancer ex vivo system via a coxsackie and adenovirus receptor-independent pathway

scientific article

A new generation of serotype chimeric infectivity-enhanced conditionally replicative adenovirals: the safety profile of ad5/3-Δ24 in advance of a phase I clinical trial in ovarian cancer patients

scientific article

A novel t(6;13)(q15;q34) translocation in a giant cell reparative granuloma (solid aneurysmal bone cyst) ⬇️

scientific article published on January 26, 2012

A phase I clinical trial of Ad5.SSTR/TK.RGD, a novel infectivity-enhanced bicistronic adenovirus, in patients with recurrent gynecologic cancer

scientific article

A phase I clinical trial of Ad5/3-Δ24, a novel serotype-chimeric, infectivity-enhanced, conditionally-replicative adenovirus (CRAd), in patients with recurrent ovarian cancer

scientific article published on 10 June 2013

Adenovirus infection activates akt1 and induces cell proliferation in pancreatic islets1.

scientific article

Adenovirus-mediated p53 tumor suppressor gene therapy of osteosarcoma

scientific article

Adenoviruses with an RGD-4C modification of the fiber knob elicit a neutralizing antibody response but continue to allow enhanced gene delivery

scientific article published in February 2005

Administration of a conditionally replicative oncolytic canine adenovirus in normal dogs

article

An adenovirus vector with a chimeric fiber derived from canine adenovirus type 2 displays novel tropism

scientific article published on June 2004

Anterior gradient protein-2 is a regulator of cellular adhesion in prostate cancer

scientific article published in 2014

Antiangiogenic cancer gene therapy by adeno-associated virus 2-mediated stable expression of the soluble FMS-like tyrosine kinase-1 receptor

scientific article published on January 2005

Breast cancer subtypes predispose the site of distant metastases

scientific article published in April 2015

CD138 (syndecan-1) expression in bone-forming tumors

scientific article published on 01 March 2012

Cancer-specific targeting of a conditionally replicative adenovirus using mRNA translational control

scientific article

Changing prognostic factors in osteosarcoma: analysis of 381 cases from two institutions

scientific article

Characterization of CXCR4 Expression in Chondrosarcoma of Bone ⬇️

scientific article published on 01 June 2011

Characterization of estrogen receptor-negative/progesterone receptor-positive breast cancer

scientific article published on 4 August 2015

Chondroblastoma-like tumor of the skull in a patient with cardio-facio-cutaneous syndrome

scientific article published on 07 August 2018

Clinical and pathological factors related to brain relapse-free survival in breast cancer patients-reply

scientific article published on 24 June 2017

Clinicopathological factors associated with survival in patients with breast cancer brain metastasis

scientific article published on 17 April 2017

Combining high selectivity of replication via CXCR4 promoter with fiber chimerism for effective adenoviral oncolysis in breast cancer

scientific article published on February 2007

Comparison of AJCC Anatomic and Clinical Prognostic Stage Groups in Breast Cancer: Analysis of 3322 Cases From a Single Institution

scientific article published on 17 July 2018

Complex analysis of a recurrent pleomorphic hyalinizing angiectatic tumor of soft parts

scientific article published on 05 July 2011

Conditionally Replicating Adenovirus Expressing TIMP2 Increases Survival in a Mouse Model of Disseminated Ovarian Cancer ⬇️

scientific article published on October 12, 2011

Conditionally replicating adenovirus expressing TIMP2 for ovarian cancer therapy

scientific article

Corrigendum to "Diagnostic utility of IDH1/2 mutations to distinguish dedifferentiated chondrosarcoma from undifferentiated pleomorphic sarcoma of bone" [Hum Pathol 2017;65:239-46].

scientific article published on 13 November 2017

Cytologic grade independently predicts survival of patients with pancreatic adenocarcinoma.

scientific article published in November 2005

Depletion of plasmacytoid dendritic cells inhibits tumor growth and prevents bone metastasis of breast cancer cells

scientific article

Detection of BRAF V600E Mutations With Next-Generation Sequencing in Infarcted Thyroid Carcinomas After Fine-Needle Aspiration

scientific article published on 01 July 2018

Detection of Merkel cell polyomavirus in formalin-fixed, paraffin-embedded tissue of Merkel cell carcinoma and correlation with prognosis

scientific article published on January 2014

Development of an optimized conditionally replicative adenoviral agent for ovarian cancer

scientific article

Diagnostic utility of IDH1/2 mutations to distinguish dedifferentiated chondrosarcoma from undifferentiated pleomorphic sarcoma of bone.

scientific article

E-cadherin/beta-catenin and CD10: a limited immunohistochemical panel to distinguish pancreatic endocrine neoplasm from solid pseudopapillary neoplasm of the pancreas on endoscopic ultrasound-guided fine-needle aspirates of the pancreas

scientific article published in December 2009

Effect of adenoviral mediated overexpression of fibromodulin on human dermal fibroblasts and scar formation in full-thickness incisional wounds

scientific article published on 12 January 2007

Enhancement of antitumor immunity in lung cancer by targeting myeloid-derived suppressor cell pathways

scientific article published on October 2013

Evaluation of lymph node numbers for adequate staging of Stage II and III colon cancer ⬇️

scientific article published on May 28, 2011

Evaluation of tissue-specific promoters in carcinomas of the cervix uteri

scientific article published on November 2004

Ex vivo transfer of the Hoxc-8-interacting domain of Smad1 by a tropism-modified adenoviral vector results in efficient bone formation in a rabbit model of spinal fusion

scientific article

Expression of osteoprotegerin from a replicating adenovirus inhibits the progression of prostate cancer bone metastases in a murine model

scientific article published on 28 January 2013

Extraskeletal aneurysmal bone cyst: Report of a case and review of the literature

scientific article published on 06 July 2017

Fluorescently tagged canine adenovirus via modification with protein IX-enhanced green fluorescent protein

scientific article published on December 2005

Foxp3 expression patterns in microscopic colitides: a clinicopathologic study of 69 patients

scientific article published on 01 June 2012

GATA3 expression in advanced breast cancer: prognostic value and organ-specific relapse.

scientific article

Gene transfer to carcinoma of the breast with fiber-modified adenoviral vectors in a tissue slice model system

scientific article published on 8 November 2005

Gene transfer to ovarian cancer versus normal tissues with fiber-modified adenoviruses

scientific article

Genetic incorporation of the protein transduction domain of Tat into Ad5 fiber enhances gene transfer efficacy

scientific article published on 24 October 2007

Identifying the safety profile of Ad5.SSTR/TK.RGD, a novel infectivity-enhanced bicistronic adenovirus, in anticipation of a phase I clinical trial in patients with recurrent ovarian cancer.

scientific article

Incorporating the survivin promoter in an infectivity enhanced CRAd-analysis of oncolysis and anti-tumor effects in vitro and in vivo.

scientific article published on July 2005

Infectivity enhanced, cyclooxygenase-2 promoter-based conditionally replicative adenovirus for pancreatic cancer ⬇️

scientific article published on October 1, 2003

Inflammatory myofibroblastic tumor of bone harboring an ALK gene amplification

scientific article published on 13 July 2019

Inter-patient variation in efficacy of five oncolytic adenovirus candidates for ovarian cancer therapy

scientific article

Intravenous delivery of adenovirus-mediated soluble FLT-1 results in liver toxicity.

scientific article published in July 2003

Introducing Biological Perspectives.

scientific article

Involvement of vitronectin in lipopolysaccaride-induced acute lung injury

scientific article published on 01 November 2007

Juvenile juxtacortical chondromyxoid fibroma of bone: a case report

scientific article published on 08 April 2008

Juxtatumoral Stromal Reactions in Uterine Endometrioid Adenocarcinoma and Their Prognostic Significance ⬇️

scientific article published on November 1, 2010

LL‐37 as a therapeutic target for late stage prostate cancer ⬇️

scientific article published on October 18, 2010

Large, clear cytoplasmic vacuolation: an under-recognized cytologic clue to distinguish solid pseudopapillary neoplasms of the pancreas from pancreatic endocrine neoplasms on fine-needle aspiration

scientific article published on 01 August 2008

Location of tumor affects local and distant immune cell type and number

scientific article published on 23 February 2017

MUC1 and MUC2 expression in pancreatic ductal carcinoma obtained by fine-needle aspiration

scientific article

Mammary analog secretory carcinoma, low-grade salivary duct carcinoma, and mimickers: a comparative study

scientific article published on 01 February 2017

Mammary analog secretory carcinoma, low-grade salivary duct carcinoma, and mimickers: a comparative study.

scientific article

Merkel cell carcinoma: correlation of KIT expression with survival and evaluation of KIT gene mutational status

scientific article

Mesenchymal stem cells as a vehicle for targeted delivery of CRAds to lung metastases of breast carcinoma

scientific article published on 13 January 2007

Metastatic inflammatory myofibroblastic tumor identified by EUS-FNA in mediastinal lymph nodes with ancillary FISH studies for ALK rearrangement.

scientific article

Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis

article

Microanatomic Distribution of Myeloid Heme Oxygenase-1 Protects against Free Radical-Mediated Immunopathology in Human Tuberculosis

scientific article published on 01 September 2019

Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression.

scientific article published in February 2003

Novel Infectivity-Enhanced Oncolytic Adenovirus with a Capsid-Incorporated Dual-Imaging Moiety for Monitoring Virotherapy in Ovarian Cancer

article

Novel infectivity-enhanced oncolytic adenovirus with a capsid-incorporated dual-imaging moiety for monitoring virotherapy in ovarian cancer

scientific article published on September 2009

Osteosarcoma in a patient with McCune-Albright syndrome and Mazabraud's syndrome: a case report emphasizing the cytological and cytogenetic findings

scientific article

PAX8 Expression in Solitary Fibrous Tumor: A Potential Diagnostic Pitfall

scientific article published on 01 March 2019

Preclinical evaluation of transcriptional targeting strategies for carcinoma of the breast in a tissue slice model system

scientific article

Productive replication of human adenovirus type 5 in canine cells.

scientific article

Prognostic Value of E-Cadherin and β-Catenin in Triple-Negative Breast Cancer

scientific article published on 25 October 2016

Prognostic factors in advanced breast cancer: Race and receptor status are significant after development of metastasis

scientific article published on 10 November 2015

Prognostic factors in patients with metastatic breast cancer at the time of diagnosis

scientific article published on 12 February 2014

Prognostic outcomes in advanced breast cancer: the metastasis-free interval is important

scientific article published on 12 October 2017

Promotion of incisional wound repair by human mesenchymal stem cell transplantation

scientific article published on 18 September 2008

Receptor conversion in metastatic breast cancer: analysis of 390 cases from a single institution

scientific article published on 03 July 2020

Reduced E-Cadherin and Aberrant β-Catenin Expression are Associated With Advanced Disease in Signet-Ring Cell Carcinomas

scientific article published on 01 July 2017

Replication of an integrin targeted conditionally replicating adenovirus on primary ovarian cancer spheroids ⬇️

scientific article published on May 1, 2003

Silencing of transforming growth factor-beta1 in situ by RNA interference for breast cancer: implications for proliferation and migration in vitro and metastasis in vivo

scientific article

Survivin promoter-based conditionally replicative adenoviruses target cholangiocarcinoma.

scientific article published on November 2006

Synchronous and metachronous bilateral breast cancer: clinicopathologic characteristics and prognostic outcomes

scientific article published on 24 July 2019

Syndecan-1 overexpression is associated with nonluminal subtypes and poor prognosis in advanced breast cancer

scientific article

Systemic osteoprotegerin gene therapy restores tumor-induced bone loss in a therapeutic model of breast cancer bone metastasis

scientific article

Targeting lung cancer using an infectivity enhanced CXCR4-CRAd

scientific article published on 17 November 2006

Targeting mesothelioma using an infectivity enhanced survivin-conditionally replicative adenoviruses

scientific article

Targeting of a conditionally replicative adenovirus agent to human squamous cell carcinomas of the head and neck

scientific article

The CD4/CD8 ratio of tumor-infiltrating lymphocytes at the tumor-host interface has prognostic value in triple-negative breast cancer

scientific article published on 6 October 2017

The RANK Pathway in Advanced Breast Cancer: Does Src Play a Role?

scientific article published on 18 July 2015

The human survivin promoter: a novel transcriptional targeting strategy for treatment of glioma

scientific article published on April 2006

The natural history of a novel, systemic, disseminated model of syngeneic mouse B-cell lymphoma

scientific article published on November 2005

Therapeutic potential of adult bone marrow-derived mesenchymal stem cells in prostate cancer bone metastasis

scientific article

Transport across a polarized monolayer of Caco-2 cells by transferrin receptor-mediated adenovirus transcytosis

scientific article published on July 2004

Validation of the revised 8th AJCC breast cancer clinical prognostic staging system: analysis of 5321 cases from a single institution

scientific article published on 10 August 2020

alpha-CaMKII controls the growth of human osteosarcoma by regulating cell cycle progression

scientific article published on 16 July 2007

p53 Nuclear accumulation and Bcl-2 expression in contiguous adenomatous components of colorectal adenocarcinomas predict aggressive tumor behavior

scientific article published on 10 December 2007

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