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List of works by Linda J Sandell

2016-The year in review at the JOR

scientific article published on 01 December 2016

A Microarray Study of Articular Cartilage in Relation to Obesity and Severity of Knee Osteoarthritis

scientific article published on 03 September 2018

A novel tumor necrosis factor alpha-responsive CCAAT/enhancer binding protein site regulates expression of the cartilage-derived retinoic acid-sensitive protein gene in cartilage

scientific journal article

A promoter element of the CD-RAP gene is required for repression of gene expression in non-cartilage tissues in vitro and in vivo.

scientific article published on March 2006

Advantages of RNA-seq compared to RNA microarrays for transcriptome profiling of anterior cruciate ligament tears

scientific article

Alpha-helical coiled-coil oligomerization domains are almost ubiquitous in the collagen superfamily

scientific article published on 14 August 2003

Alterations in apoptosis and epithelial-mesenchymal transformation in an in vitro cleft palate model.

scientific article published in March 2004

Alternative splicing of type II procollagen exon 2 is regulated by the combination of a weak 5' splice site and an adjacent intronic stem-loop cis element

scientific article published on 2 August 2005

Antiangiogenic and anticancer molecules in cartilage

scientific article published on 19 January 2012

Applications of RNA interference in the treatment of arthritis

scientific article published on 10 July 2019

BMP-2 and TGF-beta1 differentially control expression of type II procollagen and alpha 10 and alpha 11 integrins in mouse chondrocytes

scientific article published on 2 February 2010

Biomarkers for equine joint injury and osteoarthritis

scientific article published on 16 September 2017

Biomarkers in osteoarthritis

scientific article published on 23 February 2012

CCAAT/enhancer-binding protein β and NF-κB mediate high level expression of chemokine genes CCL3 and CCL4 by human chondrocytes in response to IL-1β.

scientific article

CCAAT/enhancer-binding proteins beta and delta mediate the repression of gene transcription of cartilage-derived retinoic acid-sensitive protein induced by interleukin-1 beta.

scientific article

Cartilage tolerates single impact loads of as much as half the joint fracture threshold.

scientific article published in September 2004

Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis

scientific article

Celebrate orthopedic research

scientific article published on 01 April 2015

Changes in Transcriptome-Wide Gene Expression of Anterior Cruciate Ligament Tears Based on Time From Injury

scientific article published on 06 May 2016

Characteristics of the rat supraspinatus tendon during tendon-to-bone healing after acute injury

scientific article published on 01 March 2006

Characterization of a murine type IIB procollagen-specific antibody

scientific article

Clinical Orthopaedics and Related Research, The Bone & Joint Journal, The Journal of Orthopaedic Research, and The Journal of Bone and Joint Surgery will not accept clinical research manuscripts previously posted to preprint servers

scientific article published on 03 January 2019

Clinical Orthopaedics and Related Research, The Bone & Joint Journal, the Journal of Orthopaedic Research, and The Journal of Bone and Joint Surgery Will Not Accept Clinical Research Manuscripts Previously Posted to Preprint Servers

article by Seth S Leopold et al published 2 January 2019 in Journal of Bone and Joint Surgery

Computational identification and functional validation of regulatory motifs in cartilage-expressed genes.

scientific article published on 4 September 2007

Current State in Scientific Publishing: AOA Critical Issues Symposium

scientific article published on 01 October 2019

Development and clinical application in arthritis of a new immunoassay for serum type IIA procollagen NH2 propeptide

scientific article published on 01 January 2004

Development of a peptide-siRNA nanocomplex targeting NF- κB for efficient cartilage delivery

scientific article published in Scientific Reports

Development of the supraspinatus tendon-to-bone insertion: localized expression of extracellular matrix and growth factor genes

scientific article published on December 2007

Developmental and genetic origins of murine long bone length variation

scientific article

Distribution of the transcription factors Sox9, AP-2, and [delta]EF1 in adult murine articular and meniscal cartilage and growth plate

scientific journal article

Early changes in the knee of healer and non-healer mice following non-invasive mechanical injury.

scientific article published on 3 September 2016

Early onset of disc degeneration in SM/J mice is associated with changes in ion transport systems and fibrotic events.

scientific article published on 9 April 2018

Editorial: Clinical Orthopaedics and Related Research, The Bone & Joint Journal, The Journal of Orthopaedic Research, and The Journal of Bone and Joint Surgery Will Not Accept Clinical Research Manuscripts Previously Posted to Preprint Servers

scientific article published on 01 January 2019

Effects of cigarette smoking on early medial collateral ligament healing in a mouse model.

scientific article

Effects of serum and compressive loading on the cartilage matrix synthesis and spatiotemporal deposition around chondrocytes in 3D culture

scientific article published on 14 February 2013

Egr-1 mediates transcriptional repression of COL2A1 promoter activity by interleukin-1beta

scientific article published on 11 March 2003

Emerging Concepts in Gene Therapy for Osteoarthritis.

scientific article

Etiology of osteoarthritis: genetics and synovial joint development

scientific article published on 10 January 2012

Evidence for Genetic Contribution to Variation in Posttraumatic Osteoarthritis in Mice

scientific article published on 25 January 2019

Evolving biomarkers in osteoarthritis.

scientific article published on December 2011

Extracellular matrix gene regulation

scientific article published in October 2004

Fibroblast growth factor expression during skeletal fracture healing in mice

scientific article published on March 2009

Foreword: Osteoarthritis

scientific article published on 01 August 2012

Gene expression in human meniscal tears has limited association with early degenerative changes in knee articular cartilage

scientific article published on 19 July 2016

Genetic loci that regulate ectopic calcification in response to knee trauma in LG/J by SM/J advanced intercross mice

scientific article published on 18 May 2015

Heritability of articular cartilage regeneration and its association with ear wound healing in mice

scientific article

In vivo human Cartilage oligomeric matrix protein (COMP) promoter activity

scientific article published on 7 October 2005

Inflammatory mediators: tracing links between obesity and osteoarthritis.

scientific article published on January 2011

JOR Virtual Issue on stem cells in orthopaedics

scientific article published on 11 December 2017

Journal of Orthopaedic Research: Special Issue on Stem Cells

scientific article published on 17 May 2019

Journal of Orthopaedic Research® Update, January 2018.

scientific article published on 9 February 2018

Kappa Delta Awards

scientific article published in September 2015

Medial collateral ligament healing in macrophage metalloelastase (MMP-12)-deficient mice

scientific article published on 01 November 2006

Modern molecular analysis of a traditional disease: progression in osteoarthritis

scientific article published on 01 August 2007

Molecular Influence of Anterior Cruciate Ligament Tear Remnants on Chondrocytes: A Biologic Connection between Injury and Osteoarthritis

scientific article

Molecular analysis of age and sex-related gene expression in meniscal tears with and without a concomitant anterior cruciate ligament tear.

scientific article published on March 2012

Molecular characterization of articular cartilage from young adults with femoroacetabular impingement

scientific article published on August 2013

Motion analysis, cartilage mechanics, and biology in femoroacetabular impingement: current understanding and areas of future research

scientific article

Multiple hereditary exostosis, EXT genes, and skeletal development.

scientific article published in July 2009

Musculoskeletal mechanobiology: A new era for MechanoMedicine

scientific article published on 6 February 2018

Negative regulation of chondrocyte differentiation by transcription factor AP-2alpha

scientific article published on February 2004

Novel functions for type II procollagen

scientific article published on January 2014

Nuclear protein TIA-1 regulates COL2A1 alternative splicing and interacts with precursor mRNA and genomic DNA.

scientific article

Obesity and osteoarthritis: is leptin the link?

scientific article published on 01 October 2009

Osteoarthritis following meniscus and ligament injury: insights from translational studies and animal models

scientific article published on 01 January 2019

Platelet-Rich Plasma Released From Polyethylene Glycol Hydrogels Exerts Beneficial Effects on Human Chondrocytes

scientific article published on 22 July 2019

Post-Traumatic Osteoarthritis in Mice Following Mechanical Injury to the Synovial Joint

scientific article published on 27 March 2017

Predictive validity of biochemical biomarkers in knee osteoarthritis: data from the FNIH OA Biomarkers Consortium

scientific article

Pro-inflammatory cytokine tumor necrosis factor-alpha induces bone morphogenetic protein-2 in chondrocytes via mRNA stabilization and transcriptional up-regulation

scientific article published on 11 July 2006

Processing of type II procollagen amino propeptide by matrix metalloproteinases

scientific article published on 8 November 2001

RNA Microarray Analysis of Macroscopically Normal Articular Cartilage from Knees Undergoing Partial Medial Meniscectomy: Potential Prediction of the Risk for Developing Osteoarthritis

scientific article

Recent advances in biomarkers in osteoarthritis

scientific article published on September 2011

Regeneration of articular cartilage in healer and non-healer mice

scientific article

Regenerative medicine will make orthopaedic implants obsolete in our time Orthopaedic Research Society first annual meeting debate, San Diego, March 21st, 2017

scientific article published on 24 May 2018

Regional differences in chondrocyte metabolism in osteoarthritis: a detailed analysis by laser capture microdissection

scientific article

Regulation of protein diversity by alternative pre-mRNA splicing with specific focus on chondrogenesis.

scientific article published on March 2004

Relationship of gene expression in the injured human meniscus to body mass index: a biologic connection between obesity and osteoarthritis

scientific article

Resistin induces expression of proinflammatory cytokines and chemokines in human articular chondrocytes via transcription and messenger RNA stabilization

scientific article published on July 2010

Resistin stimulates expression of chemokine genes in chondrocytes via combinatorial regulation of C/EBPβ and NF-κB

scientific article

Roles of chondrocytes in the pathogenesis of osteoarthritis

scientific article

Single high-energy impact load causes posttraumatic OA in young rabbits via a decrease in cellular metabolism.

scientific article published in March 2009

Site-1 protease ablation in the osterix-lineage in mice results in bone marrow neutrophilia and hematopoietic stem cell alterations

scientific article published on 23 June 2020

Site-1 protease is essential for endochondral bone formation in mice.

scientific article

Site-1 protease is essential to growth plate maintenance and is a critical regulator of chondrocyte hypertrophic differentiation in postnatal mice

scientific article

Site-1 protease regulates skeletal stem cell population and osteogenic differentiation in mice.

scientific article published in February 2018

Smoking delays chondrogenesis in a mouse model of closed tibial fracture healing

scientific article published in December 2006

Solution structure and dynamics of a prototypical chordin-like cysteine-rich repeat (von Willebrand Factor type C module) from collagen IIA.

scientific article

Staging of hip osteoarthritis for clinical trials on femoroacetabular impingement

scientific article

Stimulation of BMP-2 expression by pro-inflammatory cytokines IL-1 and TNF-alpha in normal and osteoarthritic chondrocytes

scientific article published in January 2003

Suppression of NF-κB activity via nanoparticle-based siRNA delivery alters early cartilage responses to injury

scientific article published on 28 September 2016

Symposium on the musculoskeletal aspects of Marfan syndrome: meeting report and state of the science

scientific article published in March 2007

The type II collagen N-propeptide, PIIBNP, inhibits cell survival and bone resorption of osteoclasts via integrin-mediated signaling

scientific article

Therapeutic efficacy of intra-articular hyaluronan derivative and platelet-rich plasma in mice following axial tibial loading

scientific article

Tissue-restricted expression of the Cdrap/Mia gene within a conserved multigenic housekeeping locus.

scientific article published on April 2004

Transcriptional Co-activators CREB-binding protein/p300 increase chondrocyte Cd-rap gene expression by multiple mechanisms including sequestration of the repressor CCAAT/enhancer-binding protein

scientific journal article

Transcriptome analysis of injured human meniscus reveals a distinct phenotype of meniscus degeneration with aging.

scientific article published on August 2013

Transcriptomic Signatures of Meniscal Tears and Articular Cartilage from Knees Undergoing Arthroscopic Partial Meniscectomy Show Evidence for Early Osteoarthritis.

scientific article

Traumatic and Degenerative Meniscus Tears Have Different Gene Expression Signatures.

scientific article published on 7 September 2016

Trimerization of the amino propeptide of type IIA procollagen using a 14-amino acid sequence derived from the coiled-coil neck domain of surfactant protein D

scientific article published on 22 August 2002

Type IIB procollagen NH(2)-propeptide induces death of tumor cells via interaction with integrins alpha(V)beta(3) and alpha(V)beta(5).

scientific article

Ultrastructural cartilage abnormalities in MIA/CD-RAP-deficient mice

scientific journal article

Uncoupling of type II collagen synthesis and degradation predicts progression of joint damage in patients with knee osteoarthritis

scientific article published on 01 October 2002

Upregulation of Runx2 and Osterix during in vitro chondrogenesis of human adipose-derived stromal cells

scientific article published on 13 May 2008

Welcome to 2019!!

scientific article published on 25 January 2019

What's new in orthopaedic research

scientific article published on 01 August 2002

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