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List of works by Hiroshi Maegawa

4-Hydroxy Hexenal Derived from Docosahexaenoic Acid Protects Endothelial Cells via Nrf2 Activation ⬇️

scientific article published on July 23, 2013

A cross-sectional association of obesity with coronary calcium among Japanese, Koreans, Japanese Americans, and U.S. whites

scientific article published on 13 June 2013

A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B

scientific article published on 05 September 2010

A role for bone marrow-derived cells in diabetic nephropathy

scientific article published on 29 November 2018

A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations

scientific article

Alcohol consumption and coronary artery calcium in middle-aged Japanese men.

scientific article published on 19 May 2006

Altered Activities of Transcription Factors and Their Related Gene Expression in Cardiac Tissues of Diabetic Rats ⬇️

scientific article published on August 1, 1998

Altered Unfolded Protein Response Is Implicated in the Age-Related Exacerbation of Proteinuria-Induced Proximal Tubular Cell Damage ⬇️

scientific article published on July 17, 2013

Anti-aging molecule, Sirt1: a novel therapeutic target for diabetic nephropathy ⬇️

scientific article published on January 30, 2013

Association Between Urinary Type IV Collagen Level and Deterioration of Renal Function in Type 2 Diabetic Patients Without Overt Proteinuria ⬇️

scientific article published on August 1, 2010

Association between single nucleotide polymorphisms within genes encoding sirtuin families and diabetic nephropathy in Japanese subjects with type 2 diabetes ⬇️

scientific article published on February 18, 2011

Association of blood levels of marine omega-3 fatty acids with coronary calcification and calcium density in Japanese men

scientific article published on 26 July 2018

Autophagy as a Therapeutic Target in Diabetic Nephropathy ⬇️

scientific article published on October 19, 2011

Autophagy: a novel therapeutic target for kidney diseases ⬇️

scientific article published on September 13, 2012

Autophagy: emerging therapeutic target for diabetic nephropathy

scientific article

Cholesteryl ester transfer protein, coronary calcium, and intima-media thickness of the carotid artery in middle-age Japanese men.

scientific article

Cilostazol Attenuates Spontaneous Microaggregation of Platelets in Type 2 Diabetic Patients With Insufficient Platelet Response to Aspirin ⬇️

scientific article published on July 1, 2013

Circulating levels of 8 cytokines and marine n-3 fatty acids and indices of obesity in Japanese, white, and Japanese American middle-aged men.

scientific article

Clinical inertia in patients with type 2 diabetes treated with oral antidiabetic drugs: results from a Japanese cohort study (JDDM53)

scientific article published on 08 July 2020

Comparative Effects of Direct Renin Inhibitor and Angiotensin Receptor Blocker on Albuminuria in Hypertensive Patients with Type 2 Diabetes. A Randomized Controlled Trial

scientific article

Comparison of HOMA-IR, HOMA-β% and disposition index between US white men and Japanese men in Japan: the ERA JUMP study

scientific article

Data set for renal sinus fat volume and visceral adipose tissue volume on computed tomography

scientific article

Effect of sleeve gastrectomy on body weight, food intake, glucose tolerance, and metabolic hormone level in two different rat models: Goto-Kakizaki and diet-induced obese rat ⬇️

scientific article published on May 28, 2013

Effects of Pemafibrate, a Novel Selective PPARα Modulator, on Lipid and Glucose Metabolism in Patients With Type 2 Diabetes and Hypertriglyceridemia: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial

scientific article published on 3 January 2018

Elevated serum levels of interleukin-18 in patients with overt diabetic nephropathy: effects of miglitol ⬇️

scientific article published on September 9, 2010

Emerging role of mammalian autophagy in ketogenesis to overcome starvation

scientific article published on April 2016

Emerging role of podocyte autophagy in the progression of diabetic nephropathy

scientific article published on 13 November 2015

Ethnic difference in liver fat content: a cross-sectional observation among Japanese American in Hawaii, Japanese in Japan, and non-Hispanic whites in United States

scientific article published on May 2013

Evaluation of a Minimally Invasive System for Measuring Glucose Area under the Curve during Oral Glucose Tolerance Tests: Usefulness of Sweat Monitoring for Precise Measurement ⬇️

scientific article published on May 1, 2013

Evaluation of a Novel Glucose Area Under the Curve (AUC) Monitoring System: Comparison with the AUC by Continuous Glucose Monitoring

scientific article published on 26 July 2016

Evidence of the lack of receptor-mediated insulin degradation in human cultured lymphocytes (RPMI-1788 line) ⬇️

scientific article published on October 1, 1983

Ezetimibe prevents hepatic steatosis induced by a high-fat but not a high-fructose diet ⬇️

scientific article published on May 28, 2013

Factors associated with progression of diabetic nephropathy in Japanese elderly patients with type 2 diabetes: Sub‐analysis of the Japanese Elderly Diabetes Intervention Trial ⬇️

scientific article published on April 1, 2012

Fenofibrate, a PPARα agonist, has renoprotective effects in mice by enhancing renal lipolysis ⬇️

scientific article published on January 26, 2011

Fructose induces tubulointerstitial injury in the kidney of mice ⬇️

scientific article published on 08 February 2012

Furosemide-associated nephrocalcinosis and renal cysts ⬇️

scientific article published on September 1, 2011

Gene therapy for neuropathic pain by silencing of TNF-α expression with lentiviral vectors targeting the dorsal root ganglion in mice

scientific article

Haematopoietic cells produce BDNF and regulate appetite upon migration to the hypothalamus ⬇️

scientific article published on January 1, 2013

High Glucose Condition Desensitizes Insulin Action at the Levels of Receptor Kinase ⬇️

scientific article published on February 1, 1995

High Glucose-Induced Abnormal Epidermal Growth Factor Signaling ⬇️

scientific article published on 01 May 1998

High Sodium Intake Is Associated With Masked Hypertension in Japanese Patients With Type 2 Diabetes and Treated Hypertension ⬇️

scientific article published on July 19, 2012

Higher levels of adiponectin in American than in Japanese men despite obesity

scientific article published on December 2006

Impaired Podocyte Autophagy Exacerbates Proteinuria in Diabetic Nephropathy

scientific article published on 17 September 2015

Inactivation of TNF-α ameliorates diabetic neuropathy in mice ⬇️

scientific article published on August 2, 2011

Increased Arterial Wall Stiffness Limits Flow Volume in the Lower Extremities in Type 2 Diabetic Patients ⬇️

scientific article published on 01 December 2001

Influence of cigarette smoking on coronary artery and aortic calcium among random samples from populations of middle-aged Japanese and Korean men

scientific article

Ketogenic essential amino acids replacement diet ameliorated hepatosteatosis with altering autophagy-associated molecules ⬇️

scientific article published on May 11, 2013

LOX-1 ligands containing apolipoprotein B and carotid intima-media thickness in middle-aged community-dwelling US Caucasian and Japanese men.

scientific article

Lifetime cigarette smoking is associated with abdominal obesity in a community-based sample of Japanese men: The Shiga Epidemiological Study of Subclinical Atherosclerosis (SESSA).

scientific article published on 16 June 2016

Lipoprotein-associated phospholipase A2 is related to risk of subclinical atherosclerosis but is not supported by Mendelian randomization analysis in a general Japanese population.

scientific article published on 23 December 2015

Localization of the Insulin-like Growth Factor I Receptor Binding Sites for the SH2 Domain Proteins p85, Syp, and GTPase Activating Protein ⬇️

scientific article published on August 11, 1995

Long chain n-3 polyunsaturated fatty acids and incidence rate of coronary artery calcification in Japanese men in Japan and white men in the USA: population based prospective cohort study.

scientific article published on 18 December 2013

Much lower prevalence of coronary calcium detected by electron-beam computed tomography among men aged 40-49 in Japan than in the US, despite a less favorable profile of major risk factors

scientific article published on 24 November 2004

O-linked β-N-acetylglucosamine modification of proteins is essential for foot process maturation and survival in podocytes

scientific article published on 27 February 2017

Obesity-mediated autophagy insufficiency exacerbates proteinuria-induced tubulointerstitial lesions

scientific article published on 3 October 2013

Octreotide improves early dumping syndrome potentially through incretins: a case report ⬇️

scientific article published on 03 April 2013

Oleate and eicosapentaenoic acid attenuate palmitate-induced inflammation and apoptosis in renal proximal tubular cell ⬇️

scientific article published on October 16, 2010

Omega-3 polyunsaturated fatty acid has an anti-oxidant effect via the Nrf-2/HO-1 pathway in 3T3-L1 adipocytes ⬇️

scientific article published on November 3, 2012

Oxidized lipoproteins found in patients with NIDDM stimulate radical-induced monocyte chemoattractant protein-1 mRNA expression in cultured human endothelial cells ⬇️

scientific article published on 01 June 1997

Pioglitazone treatment and cardiovascular event and death in subjects with type 2 diabetes without established cardiovascular disease (JDDM 36).

scientific article published on 16 July 2015

Predictive Effects of Urinary Liver-Type Fatty Acid–Binding Protein for Deteriorating Renal Function and Incidence of Cardiovascular Disease in Type 2 Diabetic Patients Without Advanced Nephropathy ⬇️

scientific article published on December 5, 2012

Presence and functional role of the rapidly activating delayed rectifier K+ current in left and right atria of adult mice ⬇️

scientific article published on September 6, 2010

Receptor binding and biological activity of [SerB24]-insulin, an abnormal mutant insulin ⬇️

scientific article published on February 29, 1984

Relationship of Insulin Resistance to Prevalence and Progression of Coronary Artery Calcification Beyond Metabolic Syndrome Components: Shiga Epidemiological Study of Subclinical Atherosclerosis.

scientific article published on 9 June 2016

Renoprotective effect of DPP-4 inhibitors against free fatty acid-bound albumin-induced renal proximal tubular cell injury

scientific article published on 20 January 2016

Replication study for the association of 3 SNP loci identified in a genome-wide association study for diabetic nephropathy in European type 1 diabetes with diabetic nephropathy in Japanese patients with type 2 diabetes ⬇️

scientific article published on March 30, 2013

Replication study for the association of rs391300 in SRR and rs17584499 in PTPRD with susceptibility to type 2 diabetes in a Japanese population

scientific article

Role of O-GlcNAcylation in the Homeostasis of Metabolic Organs and its Potential Links with Diabetes and its Complications

scientific article published on 12 July 2020

Role of nutrient-sensing signals in the pathogenesis of diabetic nephropathy

scientific article

SIRT3 attenuates palmitate-induced ROS production and inflammation in proximal tubular cells ⬇️

scientific article published on May 30, 2011

Safety and efficacy of skin patches containing loxoprofen sodium in diabetic patients with overt nephropathy ⬇️

scientific article published on August 7, 2013

Serum levels of marine-derived n-3 fatty acids in Icelanders, Japanese, Koreans, and Americans--a descriptive epidemiologic study

scientific article

Sodium-glucose cotransporter 2 inhibitors represent a paradigm shift in the prevention of heart failure in type 2 diabetes patients

scientific article published on 20 June 2020

The Influence of a Single Nucleotide Polymorphism within CNDP1 on Susceptibility to Diabetic Nephropathy in Japanese Women with Type 2 Diabetes ⬇️

scientific article published on January 16, 2013

The effects of blood pressure control levels on the renoprotection of type 2 diabetic patients without overt proteinuria ⬇️

scientific article published on December 22, 2011

Urinary Potassium Excretion and Renal and Cardiovascular Complications in Patients with Type 2 Diabetes and Normal Renal Function

scientific article

Use of MRI signal intensity of extraocular muscles to evaluate methylprednisolone pulse therapy in thyroid-associated ophthalmopathy

scientific article published on 3 December 2014

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