List of works - Age K Smilde

A classification model for the Leiden proteomics competition

scientific article

A critical assessment of feature selection methods for biomarker discovery in clinical proteomics

scientific article published on 31 October 2012

A multiway 3D QSAR analysis of a series of (S)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-methoxybenzamides

scientific article published on January 1, 1998

A structured overview of simultaneous component based data integration

scientific article

ANOVA-simultaneous component analysis (ASCA): a new tool for analyzing designed metabolomics data

scientific article

Acute Effects of Morning Light on Plasma Glucose and Triglycerides in Healthy Men and Men with Type 2 Diabetes

scientific article

Analysis of longitudinal metabolomics data

scientific article

Analyzing longitudinal microbial metabolomics data

scientific article published in September 2009

Assessing the metabolic effects of prednisolone in healthy volunteers using urine metabolic profiling

scientific article

Assessing the performance of statistical validation tools for megavariate metabolomics data

scientific article

Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis

scientific article (publication date: 2007)

Beethoven's deafness and his three styles

scientific article

Between Metabolite Relationships: an essential aspect of metabolic change ⬇️

scientific article published on May 24, 2011

Biomarkers for lysosomal storage disorders: identification and application as exemplified by chitotriosidase in Gaucher disease

scientific article

Centering, scaling, and transformations: improving the biological information content of metabolomics data

scientific article

Computational modeling of the human serum proteome response to colon resection surgery

scientific article

Crossfit analysis: a novel method to characterize the dynamics of induced plant responses

scientific article

DISCO-SCA and properly applied GSVD as swinging methods to find common and distinctive processes

scientific article

Data representations and -analyses of binary diary data in pursuit of stratifying children based on common childhood illnesses

scientific article published in PLoS ONE

Detecting regulatory mechanisms in endocrine time series measurements

scientific article

Double-check: validation of diagnostic statistics for PLS-DA models in metabolomics studies ⬇️

scientific article published on July 8, 2011

Fusion of mass spectrometry-based metabolomics data

scientific article

Gaucher disease: a model disorder for biomarker discovery

scientific article published on August 2009

Generic framework for high-dimensional fixed-effects ANOVA ⬇️

scientific article published on December 23, 2011

Heterofusion: Fusing genomics data of different measurement scales

scientific article published in 2020

How informative is your kinetic model?: using resampling methods for model invalidation

scientific article

How to distinguish healthy from diseased? Classification strategy for mass spectrometry-based clinical proteomics

scientific article

Identification of Analytical Factors Affecting Complex Proteomics Profiles Acquired in a Factorial Design Study with Analysis of Variance: Simultaneous Component Analysis

scientific article published on 9 March 2016

Identification of prognostic and diagnostic biomarkers of glucose intolerance in ApoE3Leiden mice ⬇️

scientific article published on January 10, 2012

Identifying inhibitory compounds in lignocellulosic biomass hydrolysates using an exometabolomics approach

scientific article (publication date: 21 March 2014)

Improving the analysis of designed studies by combining statistical modelling with study design information

scientific article

Increased comparability between RNA-Seq and microarray data by utilization of gene sets

scientific article published on 30 September 2020

Individual differences in metabolomics: individualised responses and between-metabolite relationships ⬇️

scientific article published on March 15, 2012

Inferring protein-protein interaction complexes from immunoprecipitation data

scientific article

Influence of Temperature on Vibrational Spectra and Consequences for the Predictive Ability of Multivariate Models ⬇️

scientific article published on 01 May 1998

Insight in modulation of inflammation in response to diclofenac intervention: a human intervention study

scientific article

Integrating functional genomics data using maximum likelihood based simultaneous component analysis

scientific article

Integration of omics data to unravel root microbiome recruitment

scientific article published in 2021

Inversion of peak elution order prevents uniform time alignment of complex liquid-chromatography coupled to mass spectrometry datasets

scientific article published on 13 November 2014

Large-scale human metabolomics studies: a strategy for data (pre-) processing and validation

scientific article published in January 2006

Metabolic fate of polyphenols in the human superorganism

scientific article

Metabolic network discovery through reverse engineering of metabolome data

scientific article

Metabolic profiling of the response to an oral glucose tolerance test detects subtle metabolic changes

scientific article

Metabolomics data exploration guided by prior knowledge

scientific article published on 25 August 2009

Multilevel data analysis of a crossover designed human nutritional intervention study

scientific article

Multivariate paired data analysis: multilevel PLSDA versus OPLSDA.

scientific article

Network identification of hormonal regulation

scientific article

New figures of merit for comprehensive functional genomics data: the metabolomics case

scientific article

Not Just a Sum? Identifying Different Types of Interplay between Constituents in Combined Interventions

scientific article

Of monkeys and men: a metabolomic analysis of static and dynamic urinary metabolic phenotypes in two species

scientific article

On the increase of predictive performance with high-level data fusion ⬇️

scientific article published on March 17, 2011

Optimized time alignment algorithm for LC-MS data: correlation optimized warping using component detection algorithm-selected mass chromatograms

scientific article

Repeated measures ASCA+ for analysis of longitudinal intervention studies with multivariate outcome data

scientific article published on 09 November 2021

Simplivariate models: ideas and first examples

scientific article

Simplivariate models: uncovering the underlying biology in functional genomics data

scientific article

Statistical data processing in clinical proteomics

scientific article

Statistical validation of megavariate effects in ASCA

scientific article

The photographer and the greenhouse: how to analyse plant metabolomics data

scientific article

Time alignment algorithms based on selected mass traces for complex LC-MS data

scientific article

To aggregate or not to aggregate high-dimensional classifiers

scientific article

Topology of transcriptional regulatory networks: testing and improving

scientific article

Towards a Hierarchical Strategy to Explore Multi-Scale IP/MS Data for Protein Complexes

scientific article

List of works by Age K Smilde

A classification model for the Leiden proteomics competition

A critical assessment of feature selection methods for biomarker discovery in clinical proteomics

A multiway 3D QSAR analysis of a series of (S)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-methoxybenzamides

A structured overview of simultaneous component based data integration

ANOVA-simultaneous component analysis (ASCA): a new tool for analyzing designed metabolomics data

Acute Effects of Morning Light on Plasma Glucose and Triglycerides in Healthy Men and Men with Type 2 Diabetes

Analysis of longitudinal metabolomics data

Analyzing longitudinal microbial metabolomics data

Assessing the metabolic effects of prednisolone in healthy volunteers using urine metabolic profiling

Assessing the performance of statistical validation tools for megavariate metabolomics data

Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis

Beethoven's deafness and his three styles

Between Metabolite Relationships: an essential aspect of metabolic change ⬇️

Biomarkers for lysosomal storage disorders: identification and application as exemplified by chitotriosidase in Gaucher disease

Centering, scaling, and transformations: improving the biological information content of metabolomics data

Computational modeling of the human serum proteome response to colon resection surgery

Crossfit analysis: a novel method to characterize the dynamics of induced plant responses

DISCO-SCA and properly applied GSVD as swinging methods to find common and distinctive processes

Data representations and -analyses of binary diary data in pursuit of stratifying children based on common childhood illnesses

Detecting regulatory mechanisms in endocrine time series measurements

Double-check: validation of diagnostic statistics for PLS-DA models in metabolomics studies ⬇️

Fusion of mass spectrometry-based metabolomics data

Gaucher disease: a model disorder for biomarker discovery

Generic framework for high-dimensional fixed-effects ANOVA ⬇️

Heterofusion: Fusing genomics data of different measurement scales

How informative is your kinetic model?: using resampling methods for model invalidation

How to distinguish healthy from diseased? Classification strategy for mass spectrometry-based clinical proteomics

Identification of Analytical Factors Affecting Complex Proteomics Profiles Acquired in a Factorial Design Study with Analysis of Variance: Simultaneous Component Analysis

Identification of prognostic and diagnostic biomarkers of glucose intolerance in ApoE3Leiden mice ⬇️

Identifying inhibitory compounds in lignocellulosic biomass hydrolysates using an exometabolomics approach

Improving the analysis of designed studies by combining statistical modelling with study design information

Increased comparability between RNA-Seq and microarray data by utilization of gene sets

Individual differences in metabolomics: individualised responses and between-metabolite relationships ⬇️

Inferring protein-protein interaction complexes from immunoprecipitation data

Influence of Temperature on Vibrational Spectra and Consequences for the Predictive Ability of Multivariate Models ⬇️

Insight in modulation of inflammation in response to diclofenac intervention: a human intervention study

Integrating functional genomics data using maximum likelihood based simultaneous component analysis

Integration of omics data to unravel root microbiome recruitment

Inversion of peak elution order prevents uniform time alignment of complex liquid-chromatography coupled to mass spectrometry datasets

Large-scale human metabolomics studies: a strategy for data (pre-) processing and validation

Metabolic fate of polyphenols in the human superorganism

Metabolic network discovery through reverse engineering of metabolome data

Metabolic profiling of the response to an oral glucose tolerance test detects subtle metabolic changes

Metabolomics data exploration guided by prior knowledge

Multilevel data analysis of a crossover designed human nutritional intervention study

Multivariate paired data analysis: multilevel PLSDA versus OPLSDA.

Network identification of hormonal regulation

New figures of merit for comprehensive functional genomics data: the metabolomics case

Not Just a Sum? Identifying Different Types of Interplay between Constituents in Combined Interventions

Of monkeys and men: a metabolomic analysis of static and dynamic urinary metabolic phenotypes in two species

On the increase of predictive performance with high-level data fusion ⬇️

Optimized time alignment algorithm for LC-MS data: correlation optimized warping using component detection algorithm-selected mass chromatograms

Repeated measures ASCA+ for analysis of longitudinal intervention studies with multivariate outcome data

Simplivariate models: ideas and first examples

Simplivariate models: uncovering the underlying biology in functional genomics data

Statistical data processing in clinical proteomics

Statistical validation of megavariate effects in ASCA

The photographer and the greenhouse: how to analyse plant metabolomics data

Time alignment algorithms based on selected mass traces for complex LC-MS data

To aggregate or not to aggregate high-dimensional classifiers

Topology of transcriptional regulatory networks: testing and improving

Towards a Hierarchical Strategy to Explore Multi-Scale IP/MS Data for Protein Complexes