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List of works by Michael Matthay

4G/5G polymorphism of plasminogen activator inhibitor-1 gene is associated with mortality in intensive care unit patients with severe pneumonia

scientific article

A Multicenter Study of the Causes and Consequences of Optimistic Expectations About Prognosis by Surrogate Decision-Makers in ICUs

scientific article published on 01 September 2019

A Simple and Robust Bedside Model for Mortality Risk in Pediatric Patients With Acute Respiratory Distress Syndrome.

scientific article published on 3 August 2016

A computational approach to understand in vitro alveolar morphogenesis

scientific article

A framework and mechanistically focused, in silico method for enabling rational translational research ⬇️

scientific article published on March 1, 2008

A multicenter study of key stakeholders' perspectives on communicating with surrogates about prognosis in intensive care units

scientific article

A prospective investigation of interleukin-8 levels in pediatric acute respiratory failure and acute respiratory distress syndrome

scientific article published on 17 April 2019

A psychometric study of the decisional conflict scale in surrogate decision makers

scientific article published on 07 July 2018

A simple classification model for hospital mortality in patients with acute lung injury managed with lung protective ventilation

scientific article published on December 2011

AIMing Immunomodulation Therapy at Sepsis

scientific article published on 01 March 2019

Accumulation of BDCA1⁺ dendritic cells in interstitial fibrotic lung diseases and Th2-high asthma

scientific article

Accuracy of physiologic dead space measurements in patients with acute respiratory distress syndrome using volumetric capnography: comparison with the metabolic monitor method.

scientific article published in April 2005

Activation of the Heat Shock Response Attenuates the Interleukin 1β–Mediated Inhibition of the Amiloride-Sensitive Alveolar Epithelial Ion Transport ⬇️

scientific article published on February 1, 2013

Activation of the alpha7 nAChR reduces acid-induced acute lung injury in mice and rats

scientific article published on 12 April 2007

Activation of the stress protein response inhibits the STAT1 signalling pathway and iNOS function in alveolar macrophages: role of Hsp90 and Hsp70.

scientific article published on April 2010

Active and Passive Cigarette Smoking and Acute Lung Injury after Severe Blunt Trauma ⬇️

scientific article published on March 18, 2011

Activity of pulmonary edema fluid interleukin-8 bound to alpha(2)-macroglobulin in patients with acute lung injury.

scientific article published in May 2002

Acute Hypoxemic Respiratory Failure after Large-Volume Thoracentesis. Mechanisms of Pleural Fluid Formation and Reexpansion Pulmonary Edema

scientific article

Acute cardiopulmonary effects of a dual-endothelin receptor antagonist on oleic acid-induced pulmonary arterial hypertension in dogs.

scientific article published in January 2004

Acute cor pulmonale and the acute respiratory distress syndrome

scientific article published on 13 January 2016

Acute effects of tidal volume strategy on hemodynamics, fluid balance, and sedation in acute lung injury

scientific article published in January 2005

Acute kidney injury in patients with acute lung injury: impact of fluid accumulation on classification of acute kidney injury and associated outcomes

scientific article

Acute lung failure

scientific article

Acute lung injury and acute respiratory distress syndrome in pregnancy

scientific article published in October 2004

Acute lung injury and the acute respiratory distress syndrome

scientific article published in October 2003

Acute lung injury and the acute respiratory distress syndrome: four decades of inquiry into pathogenesis and rational management

scientific article

Acute lung injury and the coagulation pathway: Potential role of gene polymorphisms in the protein C and fibrinolytic pathways

scientific article published on 13 June 2006

Acute lung injury edema fluid decreases net fluid transport across human alveolar epithelial type II cells

scientific article published on 19 June 2007

Acute lung injury in patients with traumatic injuries: utility of a panel of biomarkers for diagnosis and pathogenesis

scientific article

Acute lung injury: epidemiology, pathogenesis, and treatment

scientific article

Acute respiratory distress syndrome

Acute respiratory distress syndrome after surgery: can the risk be decreased?

scientific article published on 01 August 2010

Acute respiratory distress syndrome subphenotypes and differential response to simvastatin: secondary analysis of a randomised controlled trial

article by Carolyn Calfee et al published September 2018 in The Lancet. Respiratory medicine

Acute respiratory distress syndrome subphenotypes and therapy responsive traits among preclinical models: protocol for a systematic review and meta-analysis

scientific article published on 07 April 2020

Acute respiratory distress syndrome-attributable mortality in critically ill patients with sepsis

scientific article published on 23 March 2020

Acute traumatic coagulopathy: initiated by hypoperfusion: modulated through the protein C pathway?

scientific article published in May 2007

Advances and challenges in translating stem cell therapies for clinical diseases

scientific article published on 4 August 2010

Advances in critical care for the nephrologist: acute lung injury/ARDS.

scientific article published on 16 January 2008

Advancing donor management research: design and implementation of a large, randomized, placebo-controlled trial

scientific article published on 14 June 2011

Aerosolized beta(2)-adrenergic agonists achieve therapeutic levels in the pulmonary edema fluid of ventilated patients with acute respiratory failure

scientific article published on 17 May 2002

Aerosolized beta-adrenergic agonist therapy reduces pulmonary edema following lung surgery

scientific article published in April 2008

Age-, sex-, and race-based differences among patients enrolled versus not enrolled in acute lung injury clinical trials.

scientific article published on June 2010

Agonist of growth hormone-releasing hormone reduces pneumolysin-induced pulmonary permeability edema

scientific article published on 23 January 2012

Airway epithelium, inflammation, and mechanisms of disease: A tribute to Carol B. Basbaum.

scientific article published in May 2006

Airway pressures and early barotrauma in patients with acute lung injury and acute respiratory distress syndrome

scientific article

Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung

scientific article published on 31 August 2009

Allogeneic human mesenchymal stem cells restore epithelial protein permeability in cultured human alveolar type II cells by secretion of angiopoietin-1.

scientific article

Alterations in the proteome of pulmonary alveolar type II cells in the rat after hepatic ischemia-reperfusion

scientific article published on June 2008

Altered lymphatics in an ovine model of congenital heart disease with increased pulmonary blood flow ⬇️

scientific article published on December 29, 2011

Alveolar Fluid Clearance in Pathologically Relevant Conditions: In Vitro and In Vivo Models of Acute Respiratory Distress Syndrome

scientific article published on 07 April 2017

Alveolar edema fluid clearance and acute lung injury

scientific article published on 21 May 2007

Alveolar epithelial cells express mesenchymal proteins in patients with idiopathic pulmonary fibrosis ⬇️

scientific article published on April 15, 2011

Alveolar epithelial ion and fluid transport: recent progress

scientific article

Alveolar epithelium: role in lung fluid balance and acute lung injury

scientific article

Alveolar fluid clearance in patients with ARDS: does it make a difference?

scientific article

Alveolar fluid clearance is faster in women with acute lung injury compared to men.

scientific article

Alveolar macrophages contribute to alveolar barrier dysfunction in ventilator-induced lung injury

scientific article published on 28 July 2006

An official American Thoracic Society workshop report: features and measurements of experimental acute lung injury in animals

scientific article published on 01 May 2011

Animal models of transfusion-related acute lung injury

scientific article

Anti-IL-8 autoantibody:IL-8 immune complexes suppress spontaneous apoptosis of neutrophils

scientific article published on 18 May 2007

Anti-chemokine autoantibody:chemokine immune complexes activate endothelial cells via IgG receptors

scientific article published on 23 December 2008

Anti-inflammatory effects of β2 adrenergic receptor agonists in experimental acute lung injury

scientific article published on 7 February 2012

Antibacterial effect of human mesenchymal stem cells is mediated in part from secretion of the antimicrobial peptide LL-37.

scientific article published on December 2010

Applying metabolomics to uncover novel biology in ARDS.

scientific article published on 11 April 2014

Assessing Preventable Harms in the Intensive Care Unit: Data From a Tertiary Care Academic Medical Institution.

scientific article published in February 2018

Assessing the quantity of pulmonary edema in critically ill children

scientific article published on 13 August 2010

Assessment of industry data on pulmonary and immunosuppressive effects of IQOS

scientific article published on 29 August 2018

Assessment of lungs rejected for transplantation and implications for donor selection

scientific article published on 01 August 2002

Association of Elevated Plasma Interleukin-18 Level With Increased Mortality in a Clinical Trial of Statin Treatment for Acute Respiratory Distress Syndrome

scientific article published on 01 August 2019

Association of common genetic variation in the protein C pathway genes with clinical outcomes in acute respiratory distress syndrome

scientific article published on 23 May 2016

Bench to bedside: targeting coagulation and fibrinolysis in acute lung injury

scientific article published on 28 April 2006

Bench-to-bedside review: the role of activated protein C in maintaining endothelial tight junction function and its relationship to organ injury

scientific article published on January 2006

Bench-to-bedside review: the role of the alveolar epithelium in the resolution of pulmonary edema in acute lung injury

scientific article

Beta-2-agonist treatment as a potential therapy for acute inhalational lung injury

scientific article published in June 2006

Beta-adrenergic agonist therapy as a potential treatment for acute lung injury

scientific article published in February 2006

Beta2 adrenergic agonist therapy may enhance alveolar epithelial repair in patients with acute lung injury

scientific article published on 01 March 2008

Beyond Low Tidal Volume Ventilation: Treatment Adjuncts for Severe Respiratory Failure in Acute Respiratory Distress Syndrome

scientific article published on 01 November 2018

Beyond fishing: the role of discovery proteomics in mechanistic lung research

scientific article published on 14 November 2008

Biological markers of lung injury before and after the institution of positive pressure ventilation in patients with acute lung injury

scientific article published on January 2006

Biology and pathology of fibroproliferation following the acute respiratory distress syndrome

scientific article published on 6 December 2014

Biomarkers in Acute Lung Injury: Insights into the Pathogenesis of Acute Lung Injury ⬇️

scientific article published on April 1, 2011

Biomarkers increase detection of active smoking and secondhand smoke exposure in critically ill patients

scientific article

Biomarkers of inflammation, coagulation and fibrinolysis predict mortality in acute lung injury

scientific article published on 21 March 2008

Biomarkers of lung epithelial injury and inflammation distinguish severe sepsis patients with acute respiratory distress syndrome

scientific article

Biomarkers to exclude the diagnosis of ventilator-associated pneumonia

scientific article published on 28 October 2014

Blood product transfusions and clinical outcomes in pediatric patients with acute lung injury

scientific article published on May 2009

Body temperature and mortality in patients with acute respiratory distress syndrome

scientific article published on January 2015

Bone marrow-derived cells participate in stromal remodeling of the lung following acute bacterial pneumonia in mice.

scientific article published on 21 March 2008

CD47 deficiency protects mice from lipopolysaccharide-induced acute lung injury and Escherichia coli pneumonia

scientific article

Calcium flux and endothelial dysfunction during acute lung injury: a STIMulating target for therapy.

scientific article published on 22 February 2013

Can nicotine treat sepsis?

scientific article published in November 2004

Cathepsin L Helps to Defend Mice from Infection with Influenza A.

scientific article

Cecal ligation model of sepsis in mice: new insights

scientific article published on January 2013

Cell Therapy for Lung Diseases. Report from an NIH–NHLBI Workshop, November 13–14, 2012 ⬇️

scientific article published on August 1, 2013

Cell therapy for lung disease: a step forward

scientific article published in June 2013

Cell-based Therapy in Sepsis: A Step Closer

scientific article published on 26 October 2017

Cell-based therapy for acute lung injury: are we there yet?

scientific article published on June 2012

Central line infections

scientific article

Challenges in predicting which patients will develop ARDS.

scientific article published on 4 October 2016

Cigarette Smoke Exposure Worsens Endotoxin-Induced Lung Injury and Pulmonary Edema in Mice.

scientific article

Cigarette Smoke Exposure and the Acute Respiratory Distress Syndrome

scientific article published on 22 May 2015

Cigarette smoke exposure worsens acute lung injury in antibiotic-treated bacterial pneumonia in mice

scientific article published on 15 March 2018

Cigarette smoke stimulates matrix metalloproteinase-2 activity via EGR-1 in human lung fibroblasts

scientific article published on 10 November 2006

Cigarette smokers have exaggerated alveolar barrier disruption in response to lipopolysaccharide inhalation.

scientific article published on 2 February 2016

Clara cell protein CC16. A new lung epithelial biomarker for acute lung injury

scientific article published on 01 June 2009

Claudin-4 Levels Are Associated with Intact Alveolar Fluid Clearance in Human Lungs ⬇️

scientific article published on July 8, 2011

Clinical Acute Lung Injury and Acute Respiratory Distress Syndrome

scientific article

Clinical Evidence of Early Acute Lung Injury Often Precedes the Diagnosis of ALI ⬇️

scientific article published on June 24, 2012

Clinical immunology: Culprits with evolutionary ties

scientific article published on March 2010

Clinical measurement of pulmonary edema

scientific article published in December 2002

Clinical practice. Acute pulmonary edema

scientific article

Clinical review: Early treatment of acute lung injury--paradigm shift toward prevention and treatment prior to respiratory failure

scientific article published on 19 June 2012

Clinical review: Thinking outside the box--an iconoclastic view of current practice

scientific article

Clinical significance of elevated B-type natriuretic peptide in patients with acute lung injury with or without right ventricular dilatation: an observational cohort study

scientific article

Clinical trial design--effect of prone positioning on clinical outcomes in infants and children with acute respiratory distress syndrome

scientific article

Clinical trials in acute respiratory distress syndrome: challenges and opportunities.

scientific article

Clinical, Radiographic, Physiologic, and Biologic Measurements to Facilitate Personalized Medicine for ARDS.

scientific article published in November 2016

Clinically relevant concentrations of beta2-adrenergic agonists stimulate maximal cyclic adenosine monophosphate-dependent airspace fluid clearance and decrease pulmonary edema in experimental acid-induced lung injury

scientific article published in July 2004

Clinically relevant model of pneumococcal pneumonia, ARDS, and nonpulmonary organ dysfunction in mice

scientific article published on 11 September 2019

Clinician Recognition of the Acute Respiratory Distress Syndrome: Risk Factors for Under-Recognition and Trends Over Time

scientific article published on 17 April 2020

Clinician-Family Communication About Patients' Values and Preferences in Intensive Care Units

scientific article published on 01 May 2019

Coagulation-dependent mechanisms and asthma

scientific article published in July 2004

Collagen-producing lung cell atlas identifies multiple subsets with distinct localization and relevance to fibrosis

scientific article published on 21 April 2020

Combined Mesenchymal Stromal Cell Therapy and ECMO in ARDS: A Controlled Experimental Study in Sheep

scientific article published on 15 April 2020

Comparison of chest radiograph scoring to lung weight as a quantitative index of pulmonary edema in organ donors

scientific article published on 10 February 2012

Comparison of thermodilution measured extravascular lung water with chest radiographic assessment of pulmonary oedema in patients with acute lung injury ⬇️

scientific article published on August 11, 2013

Comparison of two non-bronchoscopic methods for evaluating inflammation in patients with acute hypoxaemic respiratory failure.

scientific article published on 11 August 2009

Con: corticosteroids are not indicated for treatment of acute lung injury from H1N1 viral pneumonia.

scientific article published on May 2011

Concise Review: Mesenchymal Stem (Stromal) Cells: Biology and Preclinical Evidence for Therapeutic Potential for Organ Dysfunction Following Trauma or Sepsis

scientific article published on 26 November 2016

Concise Review: Mesenchymal Stem Cells for Acute Lung Injury: Role of Paracrine Soluble Factors ⬇️

scientific article published on June 1, 2011

Conditioned media from mesenchymal stromal cells restore sodium transport and preserve epithelial permeability in an in vitro model of acute alveolar injury.

scientific article

Congenital diaphragmatic hernia prevents absorption of distal air space fluid in late-gestation rat fetuses

scientific article

Contemporary Risk Factors and Outcomes of Transfusion-Associated Circulatory Overload

scientific article published on 3 January 2018

Contemporary strategies to improve clinical trial design for critical care research: insights from the First Critical Care Clinical Trialists Workshop

scientific article published on 18 February 2020

Contribution of CFTR to apical-basolateral fluid transport in cultured human alveolar epithelial type II cells

scientific article published on 2 September 2005

Contributors

Correction: HMGB1 Accelerates Alveolar Epithelial Repair via an IL-1β- and αvβ6 Integrin-dependent Activation of TGF-β1.

scientific article published on 15 October 2013

Correspondence to: soliciting strategies for developing cell-based reference materials to advance mesenchymal stem/stromal cell research and clinical translation

scientific article published on 27 May 2014

Could Decisions to Limit Treatment Contribute to Mortality Differences between Patients with Different Presepsis Trajectories?

scientific article published on 01 April 2019

Critical care in AJRCCM 2004.

scientific article

Cystic fibrosis epithelial cell and bacterial binding

scientific article published in December 2013

Cytokine Profiles of Severe Influenza Virus-Related Complications in Children

scientific article published on 6 November 2017

Cytokine-mediated inflammation in acute lung injury ⬇️

scientific article published on December 1, 2003

Cytokines and clinical predictors in distinguishing pulmonary transfusion reactions

scientific article

Decreased expression of both the alpha1- and alpha2-subunits of the Na-K-ATPase reduces maximal alveolar epithelial fluid clearance

scientific article published on 18 March 2005

Decreased respiratory system compliance on the sixth day of mechanical ventilation is a predictor of death in patients with established acute lung injury.

scientific article

Derivation and validation of a two-biomarker panel for diagnosis of ARDS in patients with severe traumatic injuries

scientific article published on 28 August 2017

Design and implementation of the START (STem cells for ARDS Treatment) trial, a phase 1/2 trial of human mesenchymal stem/stromal cells for the treatment of moderate-severe acute respiratory distress syndrome

scientific article

Development and validation of parsimonious algorithms to classify acute respiratory distress syndrome phenotypes: a secondary analysis of randomised controlled trials

scientific article published on 13 January 2020

Diagnostic utility of B-type natriuretic peptide in patients with acute dyspnea or pleural effusions

scientific article published in March 2004

Differential effects of sustained inflation recruitment maneuvers on alveolar epithelial and lung endothelial injury

scientific article

Differentiating pulmonary transfusion reactions using recipient and transfusion factors

scientific article published on 3 May 2017

Direct visual instillation as a method for efficient delivery of fluid into the distal airspaces of anesthetized mice

scientific article published in September 2004

Distal air space epithelial fluid clearance in near-term rat fetuses is fast and requires endogenous catecholamines

scientific article published in March 2002

Distinct molecular phenotypes of direct vs indirect ARDS in single-center and multicenter studies

scientific article published on June 2015

Dysfunction of inflammation-resolving pathways is associated with exaggerated postoperative cognitive decline in a rat model of the metabolic syndrome.

scientific article published on January 2012

ECMO in severe acute respiratory distress syndrome

scientific article published on 11 January 2019

ENaCs as Both Effectors and Regulators of MiRNAs in Lung Epithelial Development and Regeneration

scientific article published on 27 November 2017

Early Plasma Matrix Metalloproteinase Profiles. A Novel Pathway in Pediatric Acute Respiratory Distress Syndrome

scientific article published on 01 January 2019

Early acute lung injury: criteria for identifying lung injury prior to the need for positive pressure ventilation*.

scientific article published on August 2013

Early elevation of plasma soluble intercellular adhesion molecule-1 in pediatric acute lung injury identifies patients at increased risk of death and prolonged mechanical ventilation

scientific article published on July 2003

Early elevation of plasma von Willebrand factor antigen in pediatric acute lung injury is associated with an increased risk of death and prolonged mechanical ventilation

scientific article published on March 2007

Early elevations in B-type natriuretic peptide levels are associated with poor clinical outcomes in pediatric acute lung injury

scientific article published on November 2009

Effect of Rosuvastatin on Acute Kidney Injury in Sepsis-Associated Acute Respiratory Distress Syndrome

article

Effect of continuous hemofiltration on hemodynamics, lung inflammation and pulmonary edema in a canine model of acute lung injury

scientific article published on 14 October 2003

Effect of prone positioning on clinical outcomes in children with acute lung injury: a randomized controlled trial

scientific article

Effects of IV Acetaminophen on Core Body Temperature and Hemodynamic Responses in Febrile Critically Ill Adults: A Randomized Controlled Trial

scientific article published on 17 March 2017

Effects of bone marrow-derived mesenchymal stromal cells on gene expression in human alveolar type II cells exposed to TNF-α, IL-1β, and IFN-γ

article

Effects of recruitment maneuvers in patients with acute lung injury and acute respiratory distress syndrome ventilated with high positive end-expiratory pressure* ⬇️

scientific article published on November 1, 2003

Elevated PAI-1 is associated with poor clinical outcomes in pediatric patients with acute lung injury

scientific article

Elevated Plasmin(ogen) as a Common Risk Factor for COVID-19 Susceptibility

scientific article published on 27 March 2020

Elevated donor plasminogen activator inhibitor-1 levels and the risk of primary graft dysfunction

scientific article published on 29 January 2018

Elevated levels of plasminogen activator inhibitor-1 in pulmonary edema fluid are associated with mortality in acute lung injury

scientific article published on 2 May 2003

Elevated levels of the receptor for advanced glycation end products, a marker of alveolar epithelial type I cell injury, predict impaired alveolar fluid clearance in isolated perfused human lungs

scientific article

Elevated plasma levels of soluble TNF receptors are associated with morbidity and mortality in patients with acute lung injury

scientific article

Elevated soluble thrombomodulin is associated with organ failure and mortality in children with acute respiratory distress syndrome (ARDS): a prospective observational cohort study

scientific article published on 14 December 2015

Elevation of KL-6, a lung epithelial cell marker, in plasma and epithelial lining fluid in acute respiratory distress syndrome.

scientific article published on 5 September 2003

Endogenous and exogenous cell-based pathways for recovery from acute respiratory distress syndrome

scientific article

Endothelial Damage During Septic Shock: Significance and Implications for Future Therapies

scientific article

Endothelial biomarkers in human sepsis: pathogenesis and prognosis for ARDS.

scientific article published in January 2018

Enhancing the safety of critically ill patients by reducing urinary and central venous catheter-related infections

scientific article

Epithelial Sodium Channel ENaC is a Modifier of the Long Term Non-progressive Phenotype Associated with F508del CFTR Mutations

scientific article published on 14 July 2017

Epithelial Sodium Channel-α Mediates the Protective Effect of the TNF-Derived TIP Peptide in Pneumolysin-Induced Endothelial Barrier Dysfunction

scientific article

Erratum to: Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction - a randomised placebo-controlled trial (KARE): study protocol.

scientific article published on 11 May 2017

Erratum to: plasma soluble thrombomodulin levels are associated with mortality in the acute respiratory distress syndrome.

scientific article

Estimating dead-space fraction for secondary analyses of acute respiratory distress syndrome clinical trials

scientific article

Evidence against aquaporin-1-dependent CO2 permeability in lung and kidney

scientific article

Evidence of temporary airway epithelial repopulation and rare clonal formation by BM-derived cells following naphthalene injury in mice.

scientific article published in September 2007

Evolving practices in critical care and potential implications for management of acute kidney injury.

scientific article published on 10 May 2006

Exosome-Based Therapy for Bronchopulmonary Dysplasia.

scientific article

Expansion of hedgehog disrupts mesenchymal identity and induces emphysema phenotype

scientific article published on 12 July 2018

External validation of a biomarker and clinical prediction model for hospital mortality in acute respiratory distress syndrome

scientific article published on 7 June 2017

Extracellular Vesicle Transfer from Mesenchymal Stromal Cells Modulates Macrophage Function in Acute Lung Injury. Basic Science and Clinical Implications.

scientific article published on 22 June 2017

Extracellular Vesicles: A New Frontier for Research in Acute Respiratory Distress Syndrome

scientific article published on 28 February 2020

Extracellular heat shock protein 72 is a marker of the stress protein response in acute lung injury

scientific article published on 05 May 2006

Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome

scientific article published on 01 August 2018

Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome

scientific article

Fatty acid transduction of nitric oxide signaling: nitrolinoleic acid mediates protective effects through regulation of the ERK pathway

scientific article

Fifty Years of Research in ARDS. Cell-based Therapy for Acute Respiratory Distress Syndrome. Biology and Potential Therapeutic Value.

scientific article

Fluid transport across cultured rat alveolar epithelial cells: a novel in vitro system

scientific article published on 27 February 2004

Formation of cysts by alveolar type II cells in three-dimensional culture reveals a novel mechanism for epithelial morphogenesis

scientific article

From protective ventilation to super-protective ventilation for acute respiratory distress syndrome ⬇️

scientific article published on January 10, 2013

Functional identification of the alveolar edema reabsorption activity of murine tumor necrosis factor-alpha

scientific article published on 3 July 2003

Future research directions in acute lung injury: summary of a National Heart, Lung, and Blood Institute working group

scientific article

Gender Differences in Authorship of Critical Care Literature

scientific article published on 01 April 2020

Genome wide association identifies PPFIA1 as a candidate gene for acute lung injury risk following major trauma

scientific article

Genomics and proteomics of lung disease: conference summary

scientific article

H(2)O(2) inhibits alveolar epithelial wound repair in vitro by induction of apoptosis

scientific article published on 30 April 2004

HMGB1 accelerates alveolar epithelial repair via an IL-1β- and αvβ6 integrin-dependent activation of TGF-β1

scientific article

Heterogeneity in sepsis: new biological evidence with clinical applications

article

Heterogeneous gene expression signatures correspond to distinct lung pathologies and biomarkers of disease severity in idiopathic pulmonary fibrosis

scientific article

High prevalence of pulmonary arterial thrombi in donor lungs rejected for transplantation.

scientific article

High tidal volume ventilation induces NOS2 and impairs cAMP- dependent air space fluid clearance

scientific article published on 31 January 2003

Higher mini-BAL total protein concentration in early ARDS predicts faster resolution of lung injury measured by more ventilator-free days

scientific article published on 17 February 2017

Higher pulmonary dead space may predict prolonged mechanical ventilation after cardiac surgery

scientific article

Higher urine desmosine levels are associated with mortality in patients with acute lung injury

scientific article published on 12 May 2006

Higher urine nitric oxide is associated with improved outcomes in patients with acute lung injury

scientific article published on 2 November 2006

Higher versus lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome

scientific article published in July 2004

Human Mesenchymal Stem (Stromal) Cells Promote the Resolution of Acute Lung Injury in Part through Lipoxin A4.

scientific article published on 26 June 2015

Human mesenchymal stem cell microvesicles for treatment of Escherichia coli endotoxin-induced acute lung injury in mice.

scientific article published on January 2014

Human mesenchymal stem cells reduce mortality and bacteremia in gram-negative sepsis in mice in part by enhancing the phagocytic activity of blood monocytes

scientific article

Human mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivo.

scientific article published on 14 March 2016

Human pulmonary endothelial cell permeability after exposure to LPS-stimulated leukocyte supernatants derived from patients with early sepsis

scientific article published on 19 July 2018

Hydrostatic mechanisms may contribute to the pathogenesis of human re-expansion pulmonary edema.

scientific article published on 17 July 2004

Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death

scientific article

Hyperoxic Acute Lung Injury ⬇️

scientific article published on January 1, 2013

Hypoxia and beta 2-agonists regulate cell surface expression of the epithelial sodium channel in native alveolar epithelial cells

scientific journal article

Hypoxia upregulates VEGF expression in alveolar epithelial cells in vitro and in vivo

scientific article published in November 2002

IL-8 inhibits cAMP-stimulated alveolar epithelial fluid transport via a GRK2/PI3K-dependent mechanism

scientific article published on 6 December 2012

IL1RL1 asthma risk variants regulate airway type 2 inflammation

scientific article published on 08 September 2016

Identification of Acute Kidney Injury Sub-phenotypes with Differing Molecular Signatures and Response to Vasopressin Therapy

scientific article published on 01 April 2019

Identification of early acute lung injury at initial evaluation in an acute care setting prior to the onset of respiratory failure

scientific article published on 02 February 2009

Identifying Clinical Research Priorities in Adult Pulmonary and Critical Care: NHLBI Working Group Report

scientific article published on 09 March 2020

Impact of Bilateral Infiltrates on Inflammatory Biomarker Levels and Clinical Outcomes of Children With Oxygenation Defect

scientific article published on 17 April 2020

Impact of low and high tidal volumes on the rat alveolar epithelial type II cell proteome

scientific article published on 15 March 2007

Improved survival after lung transplantation for adults requiring preoperative invasive mechanical ventilation: A national cohort study

scientific article published on 04 March 2020

In vitro and in vivo regulation of transepithelial lung alveolar sodium transport by serine proteases

scientific article

Incorporating Inflammation into Mortality Risk in Pediatric Acute Respiratory Distress Syndrome.

scientific article published on 28 February 2017

Increased expression of neutrophil-related genes in patients with early sepsis-induced ARDS.

scientific article published on 20 March 2015

Influence of Clinical Factors and Exclusion Criteria on Mortality in ARDS Observational Studies and Randomized Controlled Trials

scientific article published on 10 July 2018

Influenza causes prolonged disruption of the alveolar-capillary barrier in mice unresponsive to mesenchymal stem cell therapy

scientific article

Informed consent in research to improve the number and quality of deceased donor organs

scientific article published on February 2011

Inhalation therapies in acute respiratory distress syndrome.

scientific article published on July 2017

Inhaled activated protein C: a novel therapy for acute lung injury?

scientific article

Inhibiting Bruton's Tyrosine Kinase Rescues Mice from Lethal Influenza Induced Acute Lung Injury

scientific article published on 8 March 2018

Integrated control of lung fluid balance

scientific article

Integrating acute lung injury and regulation of alveolar fluid clearance

scientific article published on 12 May 2006

Integrating host response and unbiased microbe detection for lower respiratory tract infection diagnosis in critically ill adults

article published in the Proceedings of the National Academy of Sciences of the United States of America

Integrin alphavbeta5 regulates lung vascular permeability and pulmonary endothelial barrier function

scientific article published on November 2006

Intensive care unit scoring systems outperform emergency department scoring systems for mortality prediction in critically ill patients: a prospective cohort study.

scientific article published on July 2014

Interleukin-1 Receptor Antagonist Is Associated With Pediatric Acute Respiratory Distress Syndrome and Worse Outcomes in Children With Acute Respiratory Failure

scientific article published on 01 October 2018

Interleukin-1beta causes acute lung injury via alphavbeta5 and alphavbeta6 integrin-dependent mechanisms.

scientific article published on 14 February 2008

Interleukin-1beta decreases expression of the epithelial sodium channel alpha-subunit in alveolar epithelial cells via a p38 MAPK-dependent signaling pathway

scientific article published on 8 March 2005

Intra-alveolar tissue factor pathway inhibitor is not sufficient to block tissue factor procoagulant activity.

scientific article published on 29 February 2008

Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice

scientific article published on August 2007

Intratracheal instillation of alveolar type II cells enhances recovery from acute lung injury in rats.

scientific article

Invited review: Active fluid clearance from the distal air spaces of the lung

scientific article

Is a Part Better than the Whole for Cell-based Therapy for Acute Respiratory Distress Syndrome?

scientific article published on 01 May 2019

Is there a need for emerging drugs for the acute respiratory distress syndrome?

scientific article

Is there a role for beta-adrenoceptor agonists in the management of acute lung injury and the acute respiratory distress syndrome?

scientific article

Is there still a role for the lung injury score in the era of the Berlin definition ARDS?

scientific article published on 18 February 2014

Keratinocyte and hepatocyte growth factors in the lung: roles in lung development, inflammation, and repair

scientific article (publication date: May 2002)

Keratinocyte growth factor can enhance alveolar epithelial repair by nonmitogenic mechanisms

scientific article

Keratinocyte growth factor for the treatment of the acute respiratory distress syndrome (KARE): a randomised, double-blind, placebo-controlled phase 2 trial.

scientific article published on 16 May 2017

Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction--a randomised placebo-controlled trial (KARE): study protocol.

scientific article published on 18 February 2013

Keratinocyte growth factor promotes cell motility during alveolar epithelial repair in vitro

scientific article published on 01 February 2003

Keratinocyte growth factor promotes epithelial survival and resolution in a human model of lung injury

scientific article

Key stakeholders' perceptions of the acceptability and usefulness of a tablet-based tool to improve communication and shared decision making in ICUs

scientific article published on 8 March 2016

Laminin gamma2 fragments are increased in the circulation of patients with early phase acute lung injury

scientific article

Latent class analysis of ARDS subphenotypes: a secondary analysis of the statins for acutely injured lungs from sepsis (SAILS) study

scientific article published on 05 October 2018

Leukotrienes in acute lung injury: a potential therapeutic target?

scientific article published on August 2005

Lidocaine induces a reversible decrease in alveolar epithelial fluid clearance in rats

scientific article

Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury.

scientific article

Lineage-negative progenitors mobilize to regenerate lung epithelium after major injury

scientific article

Local lung hypoxia determines epithelial fate decisions during alveolar regeneration.

scientific article published on 24 July 2017

Long-Term Ozone Exposure Increases the Risk of Developing the Acute Respiratory Distress Syndrome.

scientific article published on 17 December 2015

Look before you leap: how do intensivists improve care for critically ill patients?

scientific article published on 01 February 2004

Low tidal volume reduces epithelial and endothelial injury in acid-injured rat lungs

scientific article published on 01 January 2002

Low to Moderate Air Pollutant Exposure and Acute Respiratory Distress Syndrome after Severe Trauma

scientific article published on 01 January 2019

Lower tidal volume ventilation and plasma cytokine markers of inflammation in patients with acute lung injury

scientific article published in January 2005

Lung Injury Etiology and Other Factors Influencing the Relationship Between Dead-Space Fraction and Mortality in ARDS.

scientific article published on 13 June 2017

Lung edema clearance: 20 years of progress: invited review: alveolar edema fluid clearance in the injured lung

scientific article

Lung epithelial cells induce endodermal differentiation in mouse mesenchymal bone marrow stem cells by paracrine mechanism

scientific article published on 01 October 2007

Lung epithelial fluid transport and the resolution of pulmonary edema

scientific article

Lung inflammatory environments differentially alter mesenchymal stromal cell behavior

scientific article published on 25 September 2019

Lung mast cell density defines a subpopulation of patients with idiopathic pulmonary fibrosis.

scientific article

MAPK pathway mediates EGR-1-HSP70-dependent cigarette smoke-induced chemokine production

scientific article published on May 2007

Malnutrition impairs alveolar fluid clearance in rat lungs

scientific article published on 20 February 2004

Measurement of Protein Permeability and Fluid Transport of Human Alveolar Epithelial Type II Cells Under Pathological Conditions

scientific article published on 01 January 2018

Measurement of extravascular lung water in patients with pulmonary edema

scientific article published on 25 April 2008

Measurement of extravascular lung water using the single indicator method in patients: research and potential clinical value.

scientific article published on 17 July 2009

Measuring microvascular blood flow in sepsis--a continuing challenge

scientific article published on 01 October 2002

Measuring the quantity of pulmonary edema in clinical lung injury

scientific article published in January 2010

Mechanical ventilation in acute hypoxemic respiratory failure: a review of new strategies for the practicing hospitalist

scientific article

Mechanisms of alveolar protein clearance in the intact lung

scientific article published on April 2004

Mesenchymal Stem Cell Derived Extracellular Vesicles Attenuate Pulmonary Vascular Permeability and Lung Injury Induced by Hemorrhagic Shock and Trauma.

scientific article published on 14 December 2017

Mesenchymal Stem Cells and Acute Lung Injury ⬇️

scientific article published on May 23, 2011

Mesenchymal Stem Cells and Idiopathic Pulmonary Fibrosis. Potential for Clinical Testing ⬇️

scientific article published on July 15, 2013

Mesenchymal stem (stromal) cells for treatment of ARDS: a phase 1 clinical trial

scientific article

Mesenchymal stem (stromal) cells for treatment of acute respiratory distress syndrome - authors' reply

scientific article published in April 2015

Mesenchymal stem cells and the stem cell niche: a new chapter

scientific article published on 13 April 2012

Mesenchymal stem cells enhance survival and bacterial clearance in murine Escherichia coli pneumonia.

scientific article published on 16 January 2012

Mesenchymal stem cells for acute lung injury: Preclinical evidence ⬇️

scientific article published on October 1, 2010

Mesenchymal stem cells for the prevention of bronchopulmonary dysplasia: delivering the secretome

scientific article published on 01 December 2009

Mesenchymal stem cells: mechanisms of potential therapeutic benefit in ARDS and sepsis

scientific article

Mesenchymal stromal (stem) cell therapy: an emerging immunomodulatory strategy for the adjunctive treatment of sepsis

scientific article published in February 2014

Mesenchymal stromal cells and macrophages in sepsis: new insights

scientific article published on 26 April 2018

Mesenchymally "stemming" angiogenesis

scientific article published on April 2009

Meta-Analysis of Preclinical Studies of Fibrinolytic Therapy for Acute Lung Injury

scientific article published on 20 August 2018

Meta-analysis of acute lung injury and acute respiratory distress syndrome trials

scientific article published in December 2002

Metabolomic derangements are associated with mortality in critically ill adult patients

scientific article published on 30 January 2014

Microarray analysis indicates that pulmonary edema fluid from patients with acute lung injury mediates inflammation, mitogen gene expression, and fibroblast proliferation through bioactive interleukin-1.

scientific article published in March 2002

Mitochondrial Transfer via Tunneling Nanotubes is an Important Mechanism by Which Mesenchymal Stem Cells Enhance Macrophage Phagocytosis in the In Vitro and In Vivo Models of ARDS.

scientific article published on 5 April 2016

Molecular programs of fibrotic change in aging human lung

scientific article published on 02 November 2021

Monitoring Research Blood Sampling in Critically Ill Patients: Avoiding Iatrogenic Anemia

scientific article published on 01 May 2020

Multipotent stromal stem cells from human placenta demonstrate high therapeutic potential

scientific article published on 8 May 2012

NADPH oxidase-1 plays a crucial role in hyperoxia-induced acute lung injury in mice

scientific journal article

Negative-Pressure Pulmonary Edema

scientific article published on 7 April 2016

Neuregulin-1-human epidermal receptor-2 signaling is a central regulator of pulmonary epithelial permeability and acute lung injury.

scientific article

Neutrophil sandwiches injure the microcirculation

scientific article published on April 2009

Neutrophils and their Fc gamma receptors are essential in a mouse model of transfusion-related acute lung injury.

scientific article

New Insights into Clinical and Mechanistic Heterogeneity of the Acute Respiratory Distress Syndrome: Summary of the Aspen Lung Conference 2021

scientific article published in 2022

New Strategies for Effective Therapeutics in Critically Ill Patients.

scientific article

Nonventilatory treatments for acute lung injury and ARDS.

scientific article published on March 2007

Noradrenergic Neurons Regulate Monocyte Trafficking and Mortality during Gram-Negative Peritonitis in Mice ⬇️

scientific article published on March 29, 2013

Novel aspects of urokinase function in the injured lung: role of α2-macroglobulin

scientific article

Novel molecular strategy to prevent pulmonary edema

scientific article published on May 2008

Novel role of the human alveolar epithelium in regulating intra-alveolar coagulation

scientific article published on 10 November 2006

One-year mortality and predictors of death among hospital survivors of acute respiratory distress syndrome

scientific article published on 17 January 2014

Overnight Extubation in Patients With Mechanical Ventilation: Is It Harmful?

scientific article published on 6 September 2016

Pancreatitis-associated acute lung injury: new insights

scientific article published on December 2003

Pathogenesis of Acute Respiratory Distress Syndrome

scientific article published on 01 February 2019

Pathogenetic and predictive value of biomarkers in patients with ALI and lower severity of illness: results from two clinical trials

scientific article

Pathogenetic significance of biological markers of ventilator-associated lung injury in experimental and clinical studies

scientific article published on December 2006

Pathophysiology of transfusion-related acute lung injury

scientific article published on September 2010

Patterns and Trends in Advance Care Planning Among Older Adults Who Received Intensive Care at the End of Life

scientific article published on 02 March 2020

Pediatric acute lung injury: prospective evaluation of risk factors associated with mortality

scientific article published on 23 December 2004

Peripheral blood leukocyte telomere length is associated with survival of sepsis patients

scientific article published on 16 January 2020

Perspectives, translational research, and letters to the editor

scientific article published on 01 April 2006

Pharmacotherapy of acute lung injury and the acute respiratory distress syndrome

scientific article

Phenotypes and personalized medicine in the acute respiratory distress syndrome

scientific article published on 18 November 2020

Physiologic Analysis and Clinical Performance of the Ventilatory Ratio in Acute Respiratory Distress Syndrome

scientific article published on 01 February 2019

Physiological and biochemical markers of alveolar epithelial barrier dysfunction in perfused human lungs

scientific article published on 09 March 2007

Plasma Concentrations of Soluble Suppression of Tumorigenicity-2 and Interleukin-6 Are Predictive of Successful Liberation From Mechanical Ventilation in Patients With the Acute Respiratory Distress Syndrome

scientific article published on September 2016

Plasma angiopoietin-2 as a potential causal marker in sepsis-associated ARDS development: evidence from Mendelian randomization and mediation analysis

article

Plasma angiopoietin-2 in clinical acute lung injury: prognostic and pathogenetic significance

scientific article

Plasma angiopoietin-2 outperforms other markers of endothelial injury in prognosticating pediatric ARDS mortality.

scientific article

Plasma angiopoietin-2 predicts the onset of acute lung injury in critically ill patients

scientific article published on April 2013

Plasma biomarker profiles in acute exacerbation of idiopathic pulmonary fibrosis

scientific article

Plasma interleukin-8 is not an effective risk stratification tool for adults with vasopressor-dependent septic shock

scientific article

Plasma protein C levels in patients with acute lung injury: prognostic significance

scientific article published in May 2004

Plasma receptor for advanced glycation end-products predicts duration of ICU stay and mechanical ventilation in patients after lung transplantation

scientific article published on July 2007

Plasma sRAGE Acts as a Genetically Regulated Causal Intermediate in Sepsis-associated Acute Respiratory Distress Syndrome

scientific article published on 01 January 2020

Plasma sRAGE is independently associated with increased mortality in ARDS: a meta-analysis of individual patient data

article

Plasma sTNFR1 and IL8 for prognostic enrichment in sepsis trials: a prospective cohort study

scientific article published on 09 December 2019

Plasma soluble thrombomodulin levels are associated with mortality in the acute respiratory distress syndrome.

scientific article

Plasma total fibroblast growth factor 23 levels are associated with acute kidney injury and mortality in children with acute respiratory distress syndrome

scientific article published on 05 September 2019

Plasmin improves oedematous blood-gas barrier by cleaving epithelial sodium channels

scientific article published on 04 March 2020

Platelet depletion and aspirin treatment protect mice in a two-event model of transfusion-related acute lung injury

scientific article

Pleural surface fluorescence measurement of Na+ and Cl- transport across the air space-capillary barrier

scientific article published on 30 August 2002

Polymorphonuclear leukocytes mediate Staphylococcus aureus Panton-Valentine leukocidin-induced lung inflammation and injury.

scientific article

Poor Adherence to Lung-Protective Mechanical Ventilation in Pediatric Acute Respiratory Distress Syndrome.

scientific article

Positive Cumulative Fluid Balance Is Associated With Mortality in Pediatric Acute Respiratory Distress Syndrome in the Setting of Acute Kidney Injury

scientific article published on 01 April 2019

Positive fluid balance is associated with higher mortality and prolonged mechanical ventilation in pediatric patients with acute lung injury

scientific article published on 29 May 2011

Possible hepatotoxicity of IQOS.

scientific article published on 21 August 2018

Postobstructive pulmonary edema: a case for hydrostatic mechanisms

scientific article published on 5 April 2007

Potential Value of Biomarker Signatures in Sepsis and Acute Respiratory Distress Syndrome in Children and Adults

scientific article published on 01 March 2020

Potential application of mesenchymal stem cells in acute lung injury

scientific article published on October 2009

Precision medicine for cell therapy in acute respiratory distress syndrome - Authors' reply

scientific article published on 01 April 2019

Predictive and pathogenetic value of plasma biomarkers for acute kidney injury in patients with acute lung injury.

scientific article published on December 2007

Prevalence and impact of active and passive cigarette smoking in acute respiratory distress syndrome.

scientific article

Prevention of ventilator-associated pneumonia: an evidence-based systematic review

scientific article

Priming With Endotoxin Increases Acute Lung Injury in Mice by Enhancing the Severity of Lung Endothelial Injury ⬇️

scientific article published on November 16, 2010

Profiling of ARDS pulmonary edema fluid identifies a metabolically distinct subset.

scientific article published on 3 March 2017

Prognostic and Diagnostic Value of Plasma Soluble Suppression of Tumorigenicity-2 Concentrations in Acute Respiratory Distress Syndrome ⬇️

scientific article published on November 1, 2013

Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury

scientific article

Prognostic value of pulmonary dead space in patients with the acute respiratory distress syndrome ⬇️

scientific article published on October 25, 2011

Prognostic value of surfactant proteins A and D in patients with acute lung injury.

scientific article published in January 2003

Prognostic value of the pulmonary dead-space fraction during the first 6 days of acute respiratory distress syndrome.

scientific article

Progress in modelling acute lung injury in a pre-clinical mouse model

scientific article published on 01 May 2012

Proinflammatory activity of anti-IL-8 autoantibody:IL-8 complexes in alveolar edema fluid from patients with acute lung injury

scientific article published on 16 January 2004

Proliferative regulation of alveolar epithelial type 2 progenitor cells by human Scnn1d gene

scientific article published on 18 October 2019

Prolonged hypoxia differentially regulates hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha expression in lung epithelial cells: implication of natural antisense HIF-1alpha

scientific article published on 26 January 2004

Prospective Assessment of the Feasibility of a Trial of Low Tidal Volume Ventilation for Patients with Acute Respiratory Failure

scientific article published on 01 March 2019

Prospective study on the clinical course and outcomes in transfusion-related acute lung injury*

scientific article

Prostaglandin E2 mediates IL-1beta-related fibroblast mitogenic effects in acute lung injury through differential utilization of prostanoid receptors.

scientific article published on January 2008

Protease-activated receptor-2 activation induces acute lung inflammation by neuropeptide-dependent mechanisms

scientific article

Protective effect of Growth Hormone-Releasing Hormone agonist in bacterial toxin-induced pulmonary barrier dysfunction

scientific article

Protective effect of endogenous beta-adrenergic tone on lung fluid balance in acute bacterial pneumonia in mice.

scientific article

Protective mechanisms of activated protein C in severe inflammatory disorders.

scientific article published on 14 May 2009

Protein C and thrombomodulin in human acute lung injury ⬇️

scientific article published on May 16, 2003

Protein C as a surrogate end-point for clinical trials of sepsis

scientific article published on 24 April 2008

Protein kinase C-α and arginase I mediate pneumolysin-induced pulmonary endothelial hyperpermeability

scientific article

Protein permeability in lung injury: now in real time again?

scientific article published on 26 October 2006

Proteinase-activated receptor-1 mediates elastase-induced apoptosis of human lung epithelial cells

scientific article published on 12 May 2005

Proteolytic regulation of epithelial sodium channels by urokinase plasminogen activator: cutting edge and cleavage sites

scientific article

Proteolytic release of the receptor for advanced glycation end products from in vitro and in situ alveolar epithelial cells ⬇️

scientific article published on January 21, 2011

Proteomic analysis of pulmonary edema fluid and plasma in patients with acute lung injury.

scientific article published on 23 January 2004

Proteomics: current techniques and potential applications to lung disease

scientific article published on July 2004

Protocolized sedation vs usual care in pediatric patients mechanically ventilated for acute respiratory failure: a randomized clinical trial

scientific article published on January 2015

Pulmonary Dead Space Monitoring: Identifying Subjects With ARDS at Risk of Developing Right Ventricular Dysfunction

scientific article published on 28 May 2019

Pulmonary artery catheter and fluid management in acute lung injury and the acute respiratory distress syndrome

scientific article published on December 2006

Pulmonary barriers to pneumonia and sepsis

scientific article published on 01 July 2007

Pulmonary dead space fraction and pulmonary artery systolic pressure as early predictors of clinical outcome in acute lung injury.

scientific article published on 15 June 2007

Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome

scientific article published in April 2002

Pulmonary edema fluid antioxidants are depressed in acute lung injury

scientific article published in September 2003

Pulmonary edema fluid from patients with early lung injury stimulates fibroblast proliferation through IL-1 beta-induced IL-6 expression

scientific article published on February 2004

Pulmonary mechanics and gas exchange characteristics in uncommon etiologies of acute respiratory distress syndrome

Pulmonary toxicity of e-cigarettes

scientific article

Quantifying the Severity of Acute Lung Injury Using Dead-Space Ventilation: Should the Lung Injury Score Be Updated? ⬇️

scientific article published on March 1, 2012

Quantifying unintended exposure to high tidal volumes from breath stacking dyssynchrony in ARDS: the BREATHE criteria

scientific article published on 24 June 2016

Rac1 is required for reorientation of polarity and lumen formation through a PI 3-kinase-dependent pathway.

scientific article published on 5 September 2007

Racial and ethnic disparities in mortality from acute lung injury

scientific article

Randomized Clinical Trial of a Combination of an Inhaled Corticosteroid and Beta Agonist in Patients at Risk of Developing the Acute Respiratory Distress Syndrome

scientific article published on 24 February 2017

Randomized clinical trial of activated protein C for the treatment of acute lung injury

scientific article published on 19 June 2008

Randomized, Placebo-controlled Clinical Trial of an Aerosolized β2-Agonist for Treatment of Acute Lung Injury ⬇️

scientific article published on September 1, 2011

Ratio of angiopoietin-2 to angiopoietin-1 as a predictor of mortality in acute lung injury patients.

scientific article

Reasons for nonenrollment in a clinical trial of acute lung injury

scientific article

Recent advances in mechanical ventilation

scientific article

Recent trends in acute lung injury mortality: 1996-2005.

scientific article published on May 2009

Receptor for advanced glycation end-products (RAGE) is an indicator of direct lung injury in models of experimental lung injury

scientific article published on May 2009

Receptor for advanced glycation end-products is a marker of type I cell injury in acute lung injury

scientific journal article

Recipient clinical risk factors predominate in possible transfusion-related acute lung injury

scientific article published on 8 December 2014

Rectal and Bladder Temperatures vs Forehead Core Temperatures Measured With SpotOn Monitoring System.

scientific article published in January 2018

Regulated gene expression in cultured type II cells of adult human lung

scientific article

Regulation and Repair of the Alveolar-Capillary Barrier in Acute Lung Injury ⬇️

scientific article published on January 1, 2013

Reperfusion pulmonary edema in children with tetralogy of Fallot, pulmonary atresia, and major aortopulmonary collateral arteries undergoing unifocalization procedures: A pilot study examining potential pathophysiologic mechanisms and clinical signi

scientific article published on 22 January 2014

Reply to "Letter to the Editor: Pulmonary toxicity of electronic cigarettes: more doubts than certainties".

scientific article published in November 2017

Reply: Idiopathic Pulmonary Fibrosis: A Degenerative Disease Requiring a Regenerative Approach ⬇️

scientific article published on July 15, 2013

Requisite role of the cholinergic alpha7 nicotinic acetylcholine receptor pathway in suppressing Gram-negative sepsis-induced acute lung inflammatory injury.

scientific article

Resolution of Alveolar Edema in Acute Respiratory Distress Syndrome. Physiology and Biology.

scientific article published in July 2015

Resolution of pulmonary edema. Thirty years of progress

scientific article

Risk Factors and Outcomes in Transfusion-associated Circulatory Overload ⬇️

scientific article published on January 26, 2013

Role of CFTR expressed by neutrophils in modulating acute lung inflammation and injury in mice ⬇️

scientific article published on February 8, 2011

Role of protease activated receptor 2 in experimental acute lung injury and lung fibrosis.

scientific article

Rosuvastatin for sepsis-associated acute respiratory distress syndrome

scientific article

Saving lives with high-flow nasal oxygen

scientific article published on 17 May 2015

Science review: mechanisms of ventilator-induced injury

scientific article

Secondary peritonitis: principles of diagnosis and intervention

scientific article published on 18 June 2018

Sedation protocol for critically ill pediatric patients--reply

scientific article published in May 2015

Selected contribution: mechanisms that may stimulate the resolution of alveolar edema in the transplanted human lung

scientific article published in November 2002

Sepsis and stretch: synergistic effects on alveolar epithelial cell death?

scientific article published on 01 June 2006

Sepsis: pathophysiology and clinical management

scientific article

Serotonin decreases alveolar epithelial fluid transport via a direct inhibition of the epithelial sodium channel.

scientific article

Severity scoring of lung oedema on the chest radiograph is associated with clinical outcomes in ARDS

scientific article published on 14 June 2018

Signals of vagal circuits engaging with AKT1 in α7 nAChR+CD11b+ cells lessen E. coli and LPS-induced acute inflammatory injury

scientific article published on 11 April 2017

Significance of von Willebrand factor in septic and nonseptic patients with acute lung injury

scientific article published on 16 June 2004

Silencing Bruton's tyrosine kinase in alveolar neutrophils protects mice from LPS/immune complex-induced acute lung injury

scientific article

Simulation of lung alveolar epithelial wound healing in vitro

scientific article

Simvastatin decreases lipopolysaccharide-induced pulmonary inflammation in healthy volunteers

scientific article published on 26 March 2009

Single-nucleotide polymorphisms in the β-adrenergic receptor genes are associated with lung allograft utilization

scientific article

Soluble MD-2 activity in plasma from patients with severe sepsis and septic shock

scientific article

Soluble intercellular adhesion molecule-1 and clinical outcomes in patients with acute lung injury

scientific article

Standards and recommendations for quantitative assessment of lung structure in research

scientific article published on 26 February 2010

Stem cells in sepsis and acute lung injury.

scientific article published on December 2010

Stimulation of alveolar epithelial fluid clearance in human lungs by exogenous epinephrine

scientific article published on March 2006

Subglottic secretion drainage for preventing ventilator-associated pneumonia: a meta-analysis.

scientific article

Subphenotypes in acute respiratory distress syndrome: latent class analysis of data from two randomised controlled trials

scientific article

Sugar administration is an effective adjunctive therapy in the treatment of Pseudomonas aeruginosa pneumonia

scientific article published on 21 June 2013

Surfactant Protein D is Associated with Severe Pediatric Acute Respiratory Distress Syndrome, Prolonged Ventilation, and Death in Children with Acute Respiratory Failure

scientific article published on 07 April 2020

Surfactant treatment of aspiration-induced lung injury in children

scientific article published on 01 September 2007

TGF-β and lung fluid balance in ARDS

scientific article published on 13 January 2014

TNFalpha-induced long pentraxin PTX3 expression in human lung epithelial cells via JNK.

scientific article

The Acute Respiratory Distress Syndrome: Pathogenesis and Treatment ⬇️

scientific article published on January 1, 2011

The Berlin Definition of ARDS versus Pathological Evidence of Diffuse Alveolar Damage ⬇️

scientific article published on April 1, 2013

The Continued Need for Clinical Trials in Deceased Organ Donor Management

scientific article published on 01 July 2019

The Role of Protein C in Sepsis

scientific article published in October 2001

The TLR4-PAR1 Axis Regulates Bone Marrow Mesenchymal Stromal Cell Survival and Therapeutic Capacity in Experimental Bacterial Pneumonia.

scientific article

The acute respiratory distress syndrome

scientific article published on 01 August 2012

The acute respiratory distress syndrome following isolated severe traumatic brain injury

scientific article

The acute respiratory distress syndrome in 2013.

scientific article published on 17 May 2013

The adenosine 2A receptor agonist GW328267C improves lung function after acute lung injury in rats.

scientific article published in June 2012

The alveolar epithelium can initiate the extrinsic coagulation cascade through expression of tissue factor

scientific article

The association between a Darc gene polymorphism and clinical outcomes in African American patients with acute lung injury

scientific article published on 29 December 2011

The association between physiologic dead-space fraction and mortality in subjects with ARDS enrolled in a prospective multi-center clinical trial

scientific article

The authors reply

scientific article published on 01 April 2019

The authors reply

The authors reply

The authors reply

scientific article published in April 2019

The ex vivo human lung: research value for translational science

scientific article published on 06 June 2019

The influence of race on the development of acute lung injury in trauma patients

scientific article

The lectin-like domain of tumor necrosis factor-α increases membrane conductance in microvascular endothelial cells and peritoneal macrophages

scientific article published on 01 October 1999

The pathogenetic and prognostic value of biologic markers in acute lung injury

scientific article published on 11 March 2009

The phosphatase CD148 promotes airway hyperresponsiveness through SRC family kinases.

scientific article

The potential of lipid mediator networks as ocular surface therapeutics and biomarkers

scientific article published on 28 April 2020

The pulmonary epithelium is an important mediator of ventilator-induced lung injury

scientific article published in August 2002

The role of angiotensin-converting enzyme inhibition in endotoxin-induced lung injury in rats

scientific article published on 01 February 2009

The role of protein C in sepsis

scientific article published in October 2007

The severity of shock is associated with impaired rates of net alveolar fluid clearance in clinical acute lung injury

scientific article published on 20 July 2012

The utility of clinical predictors of acute lung injury: towards prevention and earlier recognition

scientific article

The value of kinetic glomerular filtration rate estimation on medication dosing in acute kidney injury

scientific article published on 26 November 2019

Therapeutic Effects of Human Mesenchymal Stem Cell-derived Microvesicles in Severe Pneumonia in Mice.

scientific article

Therapeutic Effects of Hyaluronic Acid in Bacterial Pneumonia in Ex Vivo Perfused Human Lungs

scientific article published on 01 November 2019

Therapeutic effects of human mesenchymal stem cell microvesicles in an ex vivo perfused human lung injured with severe E. coli pneumonia

scientific article published on 03 August 2018

Therapeutic effects of human mesenchymal stem cells in ex vivo human lungs injured with live bacteria

scientific article published on April 2013

Therapeutic potential of mesenchymal stem cells for severe acute lung injury

scientific article

Therapeutic potential of mesenchymal stromal cells for acute respiratory distress syndrome

scientific article published on March 2015

Therapeutic potential of mesenchymal stromal cells in the treatment of ARDS

scientific article published on 01 November 2018

Therapeutic strategies for severe acute lung injury

scientific article published in August 2010

Therapeutic strategies to hasten the resolution of pulmonary edema

scientific article published on 01 April 2003

Therapeutic value of a lung protective ventilation strategy in acute lung injury

scientific article

Thinking outside the box: Introduction

scientific article published on 01 October 2010

Thirty years of critical care medicine

scientific article

Time to Recognition of Sepsis in the Emergency Department Using Electronic Health Record Data: A Comparative Analysis of Systemic Inflammatory Response Syndrome, Sequential Organ Failure Assessment, and Quick Sequential Organ Failure Assessment

scientific article published on 03 December 2019

Time-dependent effect of pneumonectomy on alveolar epithelial fluid clearance in rat lungs

scientific article published in October 2002

Timing of Intubation and Clinical Outcomes in Adults With Acute Respiratory Distress Syndrome

scientific article published on 15 October 2015

Tracheal aspirate RNA sequencing identifies distinct immunological features of COVID-19 ARDS

scientific article published on 26 August 2021

Transforming growth factor beta1 inhibits cystic fibrosis transmembrane conductance regulator-dependent cAMP-stimulated alveolar epithelial fluid transport via a phosphatidylinositol 3-kinase-dependent mechanism

scientific article

Transforming growth factor-beta induces fibrosis in immune cell-depleted lungs

scientific article published in September 2003

Transforming growth factor-beta1 decreases expression of the epithelial sodium channel alphaENaC and alveolar epithelial vectorial sodium and fluid transport via an ERK1/2-dependent mechanism

scientific article published on 20 August 2003

Transforming growth factor-β1 regulates lung epithelial barrier function and fluid transport ⬇️

scientific article published on December 1, 2003

Transfusion-related acute lung injury: a review

scientific article published in July 2004

Transfusion-related acute lung injury: incidence and risk factors.

scientific article published on 23 November 2011

Transgenic overexpression of granulocyte macrophage-colony stimulating factor in the lung prevents hyperoxic lung injury

scientific article published in December 2003

Trauma-associated lung injury differs clinically and biologically from acute lung injury due to other clinical disorders

scientific article published on October 2007

Treating ARDS: new hope for a tough problem

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Treatment for severe acute respiratory distress syndrome from COVID-19

scientific article published on 20 March 2020

Treatment of acute lung injury: clinical and experimental studies

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Treatment of acute lung injury: historical perspective and potential future therapies

scientific article published on August 2006

Treatment with allogeneic mesenchymal stromal cells for moderate to severe acute respiratory distress syndrome (START study): a randomised phase 2a safety trial

scientific article published on 16 November 2018

Understanding blood gas analysis.

scientific article published on 11 May 2017

Update on acute lung injury and critical care medicine 2009.

scientific article published on May 2010

Use of risk reclassification with multiple biomarkers improves mortality prediction in acute lung injury

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Validation of two multiplex platforms to quantify circulating markers of inflammation and endothelial injury in severe infection

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Variability in Pediatric Ideal Body Weight Calculation: Implications for Lung-Protective Mechanical Ventilation Strategies in Pediatric Acute Respiratory Distress Syndrome

scientific article published on 01 December 2018

Vascular pedicle width in acute lung injury: correlation with intravascular pressures and ability to discriminate fluid status

scientific article published on 7 March 2011

Ventilator-induced lung injury: in vivo and in vitro mechanisms

scientific article

Viral Pathogens and Acute Lung Injury: Investigations Inspired by the SARS Epidemic and the 2009 H1N1 Influenza Pandemic ⬇️

scientific article published on August 11, 2013

Visualization of Fra-1/AP-1 activation during LPS-induced inflammatory lung injury using fluorescence optical imaging

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Warm ischemia-induced alterations in oxidative and inflammatory proteins in hepatic Kupffer cells in rats

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What drives neutrophils to the alveoli in ARDS?

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Why does acute lung injury have no impact on mortality in patients with major trauma?

scientific article published in February 2004

Withholding and Withdrawing Life-Sustaining Therapy

scientific article published on 01 September 1991

miR-34 miRNAs Regulate Cellular Senescence in Type II Alveolar Epithelial Cells of Patients with Idiopathic Pulmonary Fibrosis

scientific article

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