List of works - Hiba El Hajj

A Critical Review of Animal Models Used in Acute Myeloid Leukemia Pathophysiology

scientific article published on 13 August 2019

A proteomic analysis unravels novel CORVET and HOPS proteins involved in Toxoplasma gondii secretory organelles biogenesis

article

ATL response to arsenic/interferon therapy is triggered by SUMO/PML/RNF4-dependent Tax degradation

scientific article

Acute disseminated encephalomyelitis and reactivation of cerebral toxoplasmosis in a child: Case report

Adult T-cell leukemia/lymphoma in the Middle East: first report of two cases from Lebanon

scientific article

Animal models on HTLV-1 and related viruses: what did we learn?

scientific article published on 21 September 2012

Antitumor Effect of the Atypical Retinoid ST1926 in Acute Myeloid Leukemia and Nanoparticle Formulation Prolongs Lifespan and Reduces Tumor Burden of Xenograft Mice

scientific article published on 15 June 2017

Characterization of Toxoplasma DegP, a rhoptry serine protease crucial for lethal infection in mice

scientific article published on 15 December 2017

Characterization, biosynthesis and fate of ROP7, a ROP2 related rhoptry protein of Toxoplasma gondii

scientific article

Combination of arsenic and interferon-α inhibits expression of KSHV latent transcripts and synergistically improves survival of mice with primary effusion lymphomas

scientific article

Conditional knock-down of a novel coccidian protein leads to the formation of aberrant apical organelles and abrogates mature rhoptry positioning in Toxoplasma gondii

scientific article published on 27 June 2018

Controversies in targeted therapy of adult T cell leukemia/lymphoma: ON target or OFF target effects?

scientific article

Deciphering the molecular basis of arsenic/interferon-alpha induced eradication of leukemia initiating cells in adult T cell leukemia.

scientific article

EAPB0203, a member of the imidazoquinoxaline family, inhibits growth and induces caspase-dependent apoptosis in T-cell lymphomas and HTLV-I-associated adult T-cell leukemia/lymphoma

scientific article

EAPB0503: An Imiquimod analog with potent in vitro activity against cutaneous leishmaniasis caused by Leishmania major and Leishmania tropica

scientific article published on 21 November 2018

Efficient invasion by Toxoplasma depends on the subversion of host protein networks.

scientific article

Evaluation of chromogenic medium and direct latex agglutination test for detection of group B streptococcus in vaginal specimens from pregnant women in Lebanon and Kuwait

scientific article published on 31 July 2014

Fatal Visceral Leishmaniasis Caused by Leishmania infantum, Lebanon.

scientific article

Gallotannin inhibits NFĸB signaling and growth of human colon cancer xenografts

scientific article published on July 2011

HTLV-1-infected HIS Rag2-/-γc-/- mice, a suitable model for in vivo investigating the effects of drugs in ATL treatment?

scientific article

Identification and characterization of Toxoplasma SIP, a conserved apicomplexan cytoskeleton protein involved in maintaining the shape, motility and virulence of the parasite.

scientific article published on 30 August 2014

Imidazoquinoxaline derivative EAPB0503: A promising drug targeting mutant nucleophosmin 1 in acute myeloid leukemia

scientific article published on 5 January 2017

Inverted topology of the Toxoplasma gondii ROP5 rhoptry protein provides new insights into the association of the ROP2 protein family with the parasitophorous vacuole membrane

scientific article published on 31 July 2006

Lenalidomide in Combination with Arsenic Trioxide: an Effective Therapy for Primary Effusion Lymphoma

scientific article published on 01 September 2020

Molecular signals in the trafficking of Toxoplasma gondii protein MIC3 to the micronemes

scientific article

Mouse Models That Enhanced Our Understanding of Adult T Cell Leukemia.

scientific article published on 28 March 2018

No significant HTLV seroprevalence in German people who inject drugs

scientific article

Phase 2 study of the efficacy and safety of the combination of arsenic trioxide, interferon alpha, and zidovudine in newly diagnosed chronic adult T-cell leukemia/lymphoma (ATL).

scientific article published in May 2009

Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF). ⬇️

scientific article

Preclinical efficacy of the synthetic retinoid ST1926 for treating adult T-cell leukemia/lymphoma

scientific article

RON4L1 is a new member of the moving junction complex in Toxoplasma gondii

scientific article published on 20 December 2017

ROP18 is a rhoptry kinase controlling the intracellular proliferation of Toxoplasma gondii

scientific article

Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells

scientific article published on 23 March 2015

Seroprevalence of Anti-Toxoplasma gondii Antibodies Among Lebanese Pregnant Women

scientific article published on 24 October 2017

Tax as a therapeutic target in ATL

Tax as a therapeutic target in ATL.

scientific article published on 28 August 2015

Tax as a therapeutic target in ATL.

scientific article

Tax ubiquitylation and SUMOylation control the dynamic shuttling of Tax and NEMO between Ubc9 nuclear bodies and the centrosome

Tax ubiquitylation and SUMOylation control the dynamic shuttling of Tax and NEMO between Ubc9 nuclear bodies and the centrosome.

scientific article

Tax-1 and Tax-2 similarities and differences: focus on post-translational modifications and NF-κB activation.

scientific article

The ROP2 family of Toxoplasma gondii rhoptry proteins: proteomic and genomic characterization and molecular modeling

scientific article

The combination of arsenic, interferon-alpha, and zidovudine restores an "immunocompetent-like" cytokine expression profile in patients with adult T-cell leukemia lymphoma.

scientific article published on 20 August 2013

The combination of arsenic, interferon-alpha, and zidovudine restores an “immunocompetent-like” micro-environment in patients with adult T-cell leukemia lymphoma.

scientific article published on 7 January 2014

The conserved apicomplexan Aurora kinase TgArk3 is involved in endodyogeny, duplication rate and parasite virulence

scientific article published on 2 February 2016

The rhoptry neck protein RON4 re-localizes at the moving junction during Toxoplasma gondii invasion

scientific article published on December 2005

Therapy-induced selective loss of leukemia-initiating activity in murine adult T cell leukemia ⬇️

scientific article

Toxoplasma gondii autophagy-related protein ATG9 is crucial for the survival of parasites in their host.

scientific article published on 19 December 2016

List of works by Hiba El Hajj

A Critical Review of Animal Models Used in Acute Myeloid Leukemia Pathophysiology

A proteomic analysis unravels novel CORVET and HOPS proteins involved in Toxoplasma gondii secretory organelles biogenesis

ATL response to arsenic/interferon therapy is triggered by SUMO/PML/RNF4-dependent Tax degradation

Acute disseminated encephalomyelitis and reactivation of cerebral toxoplasmosis in a child: Case report

Adult T-cell leukemia/lymphoma in the Middle East: first report of two cases from Lebanon

Animal models on HTLV-1 and related viruses: what did we learn?

Antitumor Effect of the Atypical Retinoid ST1926 in Acute Myeloid Leukemia and Nanoparticle Formulation Prolongs Lifespan and Reduces Tumor Burden of Xenograft Mice

Characterization of Toxoplasma DegP, a rhoptry serine protease crucial for lethal infection in mice

Characterization, biosynthesis and fate of ROP7, a ROP2 related rhoptry protein of Toxoplasma gondii

Combination of arsenic and interferon-α inhibits expression of KSHV latent transcripts and synergistically improves survival of mice with primary effusion lymphomas

Conditional knock-down of a novel coccidian protein leads to the formation of aberrant apical organelles and abrogates mature rhoptry positioning in Toxoplasma gondii

Controversies in targeted therapy of adult T cell leukemia/lymphoma: ON target or OFF target effects?

Deciphering the molecular basis of arsenic/interferon-alpha induced eradication of leukemia initiating cells in adult T cell leukemia.

EAPB0203, a member of the imidazoquinoxaline family, inhibits growth and induces caspase-dependent apoptosis in T-cell lymphomas and HTLV-I-associated adult T-cell leukemia/lymphoma

EAPB0503: An Imiquimod analog with potent in vitro activity against cutaneous leishmaniasis caused by Leishmania major and Leishmania tropica

Efficient invasion by Toxoplasma depends on the subversion of host protein networks.

Evaluation of chromogenic medium and direct latex agglutination test for detection of group B streptococcus in vaginal specimens from pregnant women in Lebanon and Kuwait

Fatal Visceral Leishmaniasis Caused by Leishmania infantum, Lebanon.

Gallotannin inhibits NFĸB signaling and growth of human colon cancer xenografts

HTLV-1-infected HIS Rag2-/-γc-/- mice, a suitable model for in vivo investigating the effects of drugs in ATL treatment?

Identification and characterization of Toxoplasma SIP, a conserved apicomplexan cytoskeleton protein involved in maintaining the shape, motility and virulence of the parasite.

Imidazoquinoxaline derivative EAPB0503: A promising drug targeting mutant nucleophosmin 1 in acute myeloid leukemia

Inverted topology of the Toxoplasma gondii ROP5 rhoptry protein provides new insights into the association of the ROP2 protein family with the parasitophorous vacuole membrane

Lenalidomide in Combination with Arsenic Trioxide: an Effective Therapy for Primary Effusion Lymphoma

Molecular signals in the trafficking of Toxoplasma gondii protein MIC3 to the micronemes

Mouse Models That Enhanced Our Understanding of Adult T Cell Leukemia.

No significant HTLV seroprevalence in German people who inject drugs

Phase 2 study of the efficacy and safety of the combination of arsenic trioxide, interferon alpha, and zidovudine in newly diagnosed chronic adult T-cell leukemia/lymphoma (ATL).

Phospho-MEK1/2 and uPAR Expression Determine Sensitivity of AML Blasts to a Urokinase-Activated Anthrax Lethal Toxin (PrAgU2/LF). ⬇️

Preclinical efficacy of the synthetic retinoid ST1926 for treating adult T-cell leukemia/lymphoma

RON4L1 is a new member of the moving junction complex in Toxoplasma gondii

ROP18 is a rhoptry kinase controlling the intracellular proliferation of Toxoplasma gondii

Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells

Seroprevalence of Anti-Toxoplasma gondii Antibodies Among Lebanese Pregnant Women

Tax as a therapeutic target in ATL

Tax as a therapeutic target in ATL.

Tax as a therapeutic target in ATL.

Tax ubiquitylation and SUMOylation control the dynamic shuttling of Tax and NEMO between Ubc9 nuclear bodies and the centrosome

Tax ubiquitylation and SUMOylation control the dynamic shuttling of Tax and NEMO between Ubc9 nuclear bodies and the centrosome.

Tax-1 and Tax-2 similarities and differences: focus on post-translational modifications and NF-κB activation.

The ROP2 family of Toxoplasma gondii rhoptry proteins: proteomic and genomic characterization and molecular modeling

The combination of arsenic, interferon-alpha, and zidovudine restores an "immunocompetent-like" cytokine expression profile in patients with adult T-cell leukemia lymphoma.

The combination of arsenic, interferon-alpha, and zidovudine restores an “immunocompetent-like” micro-environment in patients with adult T-cell leukemia lymphoma.

The conserved apicomplexan Aurora kinase TgArk3 is involved in endodyogeny, duplication rate and parasite virulence

The rhoptry neck protein RON4 re-localizes at the moving junction during Toxoplasma gondii invasion

Therapy-induced selective loss of leukemia-initiating activity in murine adult T cell leukemia ⬇️

Toxoplasma gondii autophagy-related protein ATG9 is crucial for the survival of parasites in their host.