List of works by Janneke Horn

100% reliability does not exist in diagnostics; SSEP in postanoxic coma

scientific article published on 02 August 2013

A low body temperature on arrival at hospital following out-of-hospital-cardiac-arrest is associated with increased mortality in the TTM-study.

scientific article published on 23 August 2016

A molecular biomarker to diagnose community-acquired pneumonia on intensive care unit admission

scientific article published on 29 June 2015

A structured approach to neurologic prognostication in clinical cardiac arrest trials

scientific article

Acute posthypoxic myoclonus after cardiopulmonary resuscitation

scientific article

Adjusting for confounding by indication in observational studies: a case study in traumatic brain injury

scientific article published on 18 July 2018

Admission Hyperglycemia in Critically Ill Sepsis Patients: Association With Outcome and Host Response.

scientific article

Age-dependent differences in pulmonary host responses in ARDS: a prospective observational cohort study

article

An Unbalanced Inflammatory Cytokine Response Is Not Associated With Mortality Following Sepsis: A Prospective Cohort Study.

scientific article published on 02 March 2017

Assessment of intensive care unit-acquired weakness in young and old mice: An E. coli septic peritonitis model

scientific article

Association between tidal volume size, duration of ventilation, and sedation needs in patients without acute respiratory distress syndrome: an individual patient data meta-analysis.

scientific article

Association of Gender With Outcome and Host Response in Critically Ill Sepsis Patients

scientific article published on 11 August 2017

Association of diabetes and diabetes treatment with the host response in critically ill sepsis patients

scientific article published on 06 August 2016

Associations between bolus infusion of hydrocortisone, glycemic variability and insulin infusion rate variability in critically Ill patients under moderate glycemic control.

scientific article

Associations between changes in oxygenation, dead space and driving pressure induced by the first prone position session and mortality in patients with acute respiratory distress syndrome

scientific article published on 01 December 2019

Associations between dynamics of the blood glucose level after hypoglycemia and intensive care unit mortality: a retrospective multicenter study

scientific article published on 10 July 2015

Atrial Fibrillation Following Out-of-Hospital Cardiac Arrest and Targeted Temperature Management-Are We Giving It the Attention it Deserves?

scientific article

Biologic effects of simvastatin in patients with aneurysmal subarachnoid hemorrhage: a double-blind, placebo-controlled randomized trial.

scientific article

Brain computer tomography in critically ill patients--a prospective cohort study.

scientific article published on 12 December 2012

Cardiac arrest patients have an impaired immune response, which is not influenced by induced hypothermia

scientific article

Cardiac dysfunction after aneurysmal subarachnoid hemorrhage: relationship with outcome.

scientific article

Causes and Consequences of Treatment Variation in Moderate and Severe Traumatic Brain Injury: A Multicenter Study

scientific article

Causes of Mortality in ICU-Acquired Weakness.

scientific article published in January 2017

Changes in ventilator settings and ventilation-induced lung injury in burn patients-A systematic review

scientific article published on 12 June 2019

Chronic antiplatelet therapy is not associated with alterations in the presentation, outcome, or host response biomarkers during sepsis: a propensity-matched analysis.

scientific article published on 14 January 2016

Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study

scientific article published on 29 August 2017

Clinical Characteristics and Outcomes of Patients With Cellulitis Requiring Intensive Care

scientific article published on 15 March 2017

Cognitive function after cardiac arrest and temperature management; rationale and description of a sub-study in the Target Temperature Management trial

scientific article

Comparative Analysis of the Host Response to Community-acquired and Hospital-acquired Pneumonia in Critically Ill Patients

scientific article published on 6 June 2016

Death after awakening from post-anoxic coma: the "Best CPC" project

Detailed statistical analysis plan for the target temperature management after out-of-hospital cardiac arrest trial

scientific article published on 17 September 2013

Diagnostic accuracy of quantitative neuromuscular ultrasound for the diagnosis of intensive care unit-acquired weakness: a cross-sectional observational study

scientific article

Early Prediction of Intensive Care Unit-Acquired Weakness: A Multicenter External Validation Study

scientific article published on 01 January 2018

Early Treatment Decisions in Poor-Grade Patients with Subarachnoid Hemorrhage

scientific article published on 02 August 2018

Early prediction of intensive care unit-acquired weakness using easily available parameters: a prospective observational study

scientific article

Early predictors of poor outcome after out-of-hospital cardiac arrest

scientific article

Effect of On-Demand vs Routine Nebulization of Acetylcysteine With Salbutamol on Ventilator-Free Days in Intensive Care Unit Patients Receiving Invasive Ventilation: A Randomized Clinical Trial

scientific article published on 01 March 2018

Effect of a Low vs Intermediate Tidal Volume Strategy on Ventilator-Free Days in Intensive Care Unit Patients Without ARDS: A Randomized Clinical Trial

scientific article published in The Journal of the American Medical Association

Electroencephalographic reactivity as predictor of neurological outcome in postanoxic coma: A multicenter prospective cohort study

scientific article published on 08 June 2019

Electroencephalography (EEG) for neurological prognostication after cardiac arrest and targeted temperature management; rationale and study design

scientific article

Electronic implementation of a novel surveillance paradigm for ventilator-associated events. Feasibility and validation.

scientific article published on April 2014

Epidemiology of Multiple Herpes Viremia in Previously Immunocompetent Patients With Septic Shock

scientific article published on 4 February 2017

Epidemiology, Management, and Risk-Adjusted Mortality of ICU-Acquired Enterococcal Bacteremia.

scientific article published on 15 July 2015

Epidemiology, severity classification, and outcome of moderate and severe traumatic brain injury: a prospective multicenter study

scientific article published on 27 September 2011

Estimated dead space fraction and the ventilatory ratio are associated with mortality in early ARDS

scientific article published on 21 November 2019

Extracellular histone H3 levels are inversely correlated with antithrombin levels and platelet counts and are associated with mortality in sepsis patients

scientific article published on 23 July 2015

Factors influencing intracranial pressure monitoring guideline compliance and outcome after severe traumatic brain injury

scientific article published in June 2012

Feasibility and diagnostic accuracy of early electrophysiological recordings for ICU-acquired weakness: an observational cohort study

scientific article published on 01 June 2015

Feasibility of Muscle Activity Assessment With Surface Electromyography During Bed Cycling Exercise In Intensive Care Unit Patients

scientific article published on 02 October 2018

Feasibility of exercise testing in patients who are critically ill: a prospective, observational multicenter study

scientific article published on 22 August 2018

Functional Recovery in Patients With and Without Intensive Care Unit-Acquired Weakness

scientific article published in April 2017

Head computed tomography for prognostication of poor outcome in comatose patients after cardiac arrest and targeted temperature management

scientific article published on 4 July 2017

Heliox Improves Carbon Dioxide Removal during Lung Protective Mechanical Ventilation

scientific article published on 7 December 2014

Heliox allows for lower minute volume ventilation in an animal model of ventilator-induced lung injury

scientific article

Helium ventilation for treatment of post-cardiac arrest syndrome: A safety and feasibility study.

scientific article published on 26 July 2016

High-sensitivity troponin-T as a prognostic marker after out-of-hospital cardiac arrest - A targeted temperature management (TTM) trial substudy.

scientific article published on October 2016

How to assess prognosis after cardiac arrest and therapeutic hypothermia

scientific article

Hypothermia after CPR prolongs conduction times of somatosensory evoked potentials

scientific article published on 01 August 2013

Impact of HIV infection on the presentation, outcome and host response in patients admitted to the intensive care unit with sepsis; a case control study

scientific article published on 10 October 2016

Impact of ICU-acquired weakness on post-ICU physical functioning: a follow-up study

scientific article published on 27 April 2015

Impact of time to return of spontaneous circulation on neuroprotective effect of targeted temperature management at 33 or 36 degrees in comatose survivors of out-of hospital cardiac arrest

scientific article published on 7 July 2015

Incidence, Risk Factors, and Attributable Mortality of Secondary Infections in the Intensive Care Unit After Admission for Sepsis

scientific article published on 15 March 2016

Incorporation of Daily Goals in Daily Care Planning Does Not Shorten Length of Stay in the Intensive Care Unit

scientific article published on 01 April 2018

Increased Early Systemic Inflammation in ICU-Acquired Weakness; A Prospective Observational Cohort Study

scientific article published on 27 March 2017

Increased mortality in elderly patients with acute respiratory distress syndrome is not explained by host response

scientific article published on 29 October 2019

Induced Hypertension in Preventing Cerebral Infarction in Delayed Cerebral Ischemia After Subarachnoid Hemorrhage

scientific article published on 01 November 2018

Induced hypothermia and determination of neurological outcome after CPR in ICUs in the Netherlands: results of a survey

scientific article published in February 2010

Induced hypothermia is associated with reduced circulating subunits of mitochondrial DNA in cardiac arrest patients

scientific article published on 13 April 2017

Induced hypothermia is protective in a rat model of pneumococcal pneumonia associated with increased adenosine triphosphate availability and turnover*.

scientific article published in March 2012

Infectious complications after out-of-hospital cardiac arrest-A comparison between two target temperatures.

scientific article published on 16 December 2016

Interobserver agreement of Centers for Disease Control and Prevention criteria for classifying infections in critically ill patients

scientific article published on October 2013

Interrater variability of EEG interpretation in comatose cardiac arrest patients

scientific article

Iron metabolism in critically ill patients developing anemia of inflammation: a case control study.

scientific article published on 2 May 2018

Is critical illness neuromyopathy and duration of mechanical ventilation decreased by strict glucose control?

scientific article published on June 2011

Is gentamicin affecting the neuromuscular system of critically ill patients?

scientific article published on 10 March 2015

Kinase activity is impaired in neutrophils of sepsis patients

scientific article published on 04 December 2018

Mean arterial pressure during targeted temperature management and renal function after out-of-hospital cardiac arrest

scientific article published on 18 December 2018

Microbiological profile of nosocomial infections following cardiac arrest: Insights from the targeted temperature management (TTM) trial

scientific article published on 04 February 2020

Molecular Biomarker to Assist in Diagnosing Abdominal Sepsis upon ICU Admission

scientific article published on 01 April 2018

Mortality and neurological outcome in the elderly after target temperature management for out-of-hospital cardiac arrest.

scientific article

Multicenter evaluation of the course of coagulopathy in patients with isolated traumatic brain injury: relation to CT characteristics and outcome.

scientific article

Muscle and nerve inflammation in intensive care unit-acquired weakness: a systematic translational review

scientific article

Muscle weakness in a S. pneumoniae sepsis mouse model

scientific article published on 01 January 2019

Myocardial Injury in Critically Ill Patients with Community-acquired Pneumonia. A Cohort Study

scientific article published on 01 May 2019

Myocardial Injury in Patients With Sepsis and Its Association With Long-Term Outcome

scientific article published in February 2018

Nebulized C1-Esterase Inhibitor does not Reduce Pulmonary Complement Activation in Rats with Severe Streptococcus Pneumoniae Pneumonia.

scientific article published on 28 September 2016

Nebulized Heparin in Burn Patients with Inhalation Trauma-Safety and Feasibility

scientific article published on 25 March 2020

Nebulized heparin for patients under mechanical ventilation: an individual patient data meta-analysis

scientific article

Neurofilaments as a plasma biomarker for ICU-acquired weakness: an observational pilot study

scientific article

Neurologic Function and Health-Related Quality of Life in Patients Following Targeted Temperature Management at 33°C vs 36°C After Out-of-Hospital Cardiac Arrest: A Randomized Clinical Trial

scientific article published in June 2015

Neurological prognostication after cardiac arrest and targeted temperature management 33°C versus 36°C: Results from a randomised controlled clinical trial.

scientific article published on 25 April 2015

Neuron-Specific Enolase as a Predictor of Death or Poor Neurological Outcome After Out-of-Hospital Cardiac Arrest and Targeted Temperature Management at 33°C and 36°C.

scientific article published on May 2015

No association between systemic complement activation and intensive care unit-acquired weakness.

scientific article

Opinions and Management of Hypothermic Sepsis: Results from an Online Survey

scientific article published on 24 June 2019

Outcome prediction in moderate and severe traumatic brain injury: a focus on computed tomography variables

scientific article published in August 2013

PReVENT--protective ventilation in patients without ARDS at start of ventilation: study protocol for a randomized controlled trial

scientific article published on 24 May 2015

Pharmacodynamics and Pharmacokinetics of Lidocaine in a Rodent Model of Diabetic Neuropathy

scientific article published on 15 December 2017

Plasma fractalkine is a sustained marker of disease severity and outcome in sepsis patients.

scientific article

Plasma suPAR as a prognostic biological marker for ICU mortality in ARDS patients

scientific article published on 23 June 2015

Platelet Toll-like receptor expression and activation induced by lipopolysaccharide and sepsis.

scientific article published on 12 March 2018

Point accuracy and reliability of an interstitial continuous glucose-monitoring device in critically ill patients: a prospective study

scientific article

Potential of Parameters of Iron Metabolism for the Diagnosis of Anemia of Inflammation in the Critically Ill

scientific article published on 03 May 2019

Practice of mechanical ventilation in cardiac arrest patients and effects of targeted temperature management: A substudy of the targeted temperature management trial

scientific article published on 12 May 2018

Prediction of extubation failure in Intensive Care Unit: systematic review of parameters investigated

scientific article published on 09 July 2018

Predictive value of interleukin-6 in post-cardiac arrest patients treated with targeted temperature management at 33 °C or 36 °C.

scientific article published on 22 October 2015

Predictive value of neurological examination for early cortical responses to somatosensory evoked potentials in patients with postanoxic coma

scientific article published on 2 September 2011

Predictors of outcome in World Federation of Neurologic Surgeons grade V aneurysmal subarachnoid hemorrhage patients.

scientific article published in December 2011

Preventive nebulization of mucolytic agents and bronchodilating drugs in invasively ventilated intensive care unit patients (NEBULAE): study protocol for a randomized controlled trial

scientific article

Prior Use of Calcium Channel Blockers Is Associated With Decreased Mortality in Critically Ill Patients With Sepsis: A Prospective Observational Study.

scientific article published on 10 January 2017

Prognosis in moderate and severe traumatic brain injury: external validation of the IMPACT models and the role of extracranial injuries.

scientific article

Prognosis of coma after therapeutic hypothermia: a prospective cohort study

scientific article published on 01 February 2012

Prognostic significance of clinical seizures after cardiac arrest and target temperature management

scientific article published on 2 February 2017

Prognostication after cardiac arrest

scientific article

Prognostication in comatose survivors of cardiac arrest: an advisory statement from the European Resuscitation Council and the European Society of Intensive Care Medicine

scientific article published on 01 December 2014

Prognostication in comatose survivors of cardiac arrest: an advisory statement from the European Resuscitation Council and the European Society of Intensive Care Medicine.

scientific article

Protein S100 as outcome predictor after out-of-hospital cardiac arrest and targeted temperature management at 33 °C and 36 °C.

scientific article

Pulmonary complement depositions in autopsy of critically ill patients have no relation with ARDS

scientific article published on 25 July 2019

Quantitative versus standard pupillary light reflex for early prognostication in comatose cardiac arrest patients: an international prospective multicenter double-blinded study

scientific article published on 26 November 2018

RELAx - REstricted versus Liberal positive end-expiratory pressure in patients without ARDS: protocol for a randomized controlled trial.

scientific article published on 9 May 2018

Reduced Responsiveness of Blood Leukocytes to Lipopolysaccharide Does not Predict Nosocomial Infections in Critically Ill Patients

scientific article

Reply to letter: False positive absent somatosensory evoked potentials in cardiac arrest with therapeutic hypothermia

scientific article published on 11 June 2014

Return to Work and Participation in Society After Out-of-Hospital Cardiac Arrest

scientific article

Risk factors, host response and outcome of hypothermic sepsis.

scientific article

Risk stratification using SpO2/FiO2 and PEEP at initial ARDS diagnosis and after 24 h in patients with moderate or severe ARDS.

scientific article published on 25 October 2017

Routine use of the confusion assessment method for the intensive care unit: a multicenter study

scientific article published on 11 May 2011

Selective Digestive Tract Decontamination Decreases Time on Ventilator in Guillain–Barré Syndrome

scholarly article by Martine E. Bos Eyssen et al published 6 April 2011 in Neurocritical Care

Selective decontamination of the digestive tract halves the prevalence of ventilator-associated pneumonia compared to selective oral decontamination.

scientific article published on 11 May 2017

Sepsis Patients Display a Reduced Capacity to Activate Nuclear Factor-κB in Multiple Cell Types

scientific article published on 24 February 2017

Serum Neurofilament Light Chain for Prognosis of Outcome After Cardiac Arrest

scientific article published on 01 January 2019

Somatosensory Evoked Potentials in Patients with Hypoxic-Ischemic Brain Injury

scientific article published on February 2017

Spontaneous hypothermia on intensive care unit admission is a predictor of unfavorable neurological outcome in patients after resuscitation: an observational cohort study

scientific article

Standardized EEG interpretation accurately predicts prognosis after cardiac arrest

scientific article published on 10 February 2016

Survey on current practices for neurological prognostication after cardiac arrest

scientific article published on 9 February 2015

Target Temperature Management after out-of-hospital cardiac arrest--a randomized, parallel-group, assessor-blinded clinical trial--rationale and design.

scientific article published on April 2012

Target temperature management of 33°C and 36°C in patients with out-of-hospital cardiac arrest with initial non-shockable rhythm - a TTM sub-study.

scientific article

Targeted temperature management after out-of-hospital cardiac arrest: certainties and uncertainties

scientific article published on 22 July 2014

Targeted temperature management at 33°C versus 36°C after cardiac arrest

scientific article published on 17 November 2013

The Host Response in Patients with Sepsis Developing Intensive Care Unit-acquired Secondary Infections

scientific article published on 20 January 2017

The Inter-rater Variability of Clinical Assessment in Post-anoxic Myoclonus.

scientific article published on 13 July 2017

The authors reply

scientific article published on 01 November 2017

The effect of induced hypothermia on respiratory parameters in mechanically ventilated patients ⬇️

scientific article published on October 14, 2010

The host response in critically ill sepsis patients on statin therapy: a prospective observational study.

scientific article published on 18 January 2018

The influence of rewarming after therapeutic hypothermia on outcome after cardiac arrest

scientific article published on 18 April 2012

Thrombocytopenia is associated with a dysregulated host response in critically ill sepsis patients

scientific article

Time course and risk factors for myocardial dysfunction after aneurysmal subarachnoid hemorrhage

scientific article

Time to awakening after cardiac arrest and the association with target temperature management

scientific article published on 22 January 2018

Time to start of cardiopulmonary resuscitation and the effect of target temperature management at 33°C and 36°C.

scientific article published on 16 December 2015

Transesophageal Versus Surface Electromyography of the Diaphragm in Ventilated Subjects

scientific article published on 31 March 2020

Treatment of electroencephalographic status epilepticus after cardiopulmonary resuscitation (TELSTAR): study protocol for a randomized controlled trial

scientific article

Two cases of tetanus?

scientific article published on 01 November 2006

Update in Neurocritical Care: a summary of the 2018 Paris international conference of the French Society of Intensive Care

article

Usefulness of Serum B-Type Natriuretic Peptide Levels in Comatose Patients Resuscitated from Out-of-Hospital Cardiac Arrest to Predict Outcome.

scientific article published on 19 July 2016

Paulina is supported by:

About Paulina

Help