List of works - Geoffrey I Shapiro

A Phase I Trial of Vorinostat and Alvocidib in Patients with Relapsed, Refractory, or Poor Prognosis Acute Leukemia, or Refractory Anemia with Excess Blasts-2 ⬇️

scientific article published on March 20, 2013

A phase Ib open-label dose escalation study of the safety, pharmacokinetics, and pharmacodynamics of cobimetinib (GDC-0973) and ipatasertib (GDC-0068) in patients with locally advanced or metastatic solid tumors

scientific article published on 31 July 2020

ACTR-93. A PHASE I STUDY OF MLN0128 (TAK-228) AND BEVACIZUMAB IN PATIENTS WITH ADVANCED SOLID TUMORS INCLUDING GLIOBLASTOMA

ATNT-18A PHASE I STUDY OF MLN0128 AND BEVACIZUMAB IN PATIENTS WITH RECURRENT GLIOBLASTOMA AND OTHER SOLID TUMORS.

scientific article

An Anatomical Site and Genetic-Based Prognostic Model for Patients With Nuclear Protein in Testis (NUT) Midline Carcinoma: Analysis of 124 Patients

scientific article published on 06 November 2019

Chemotherapy-induced p53-dependent and -independent DNA damage responses are enhanced by poly(ADP-ribose) polymerase (PARP) inhibition in BRCA-proficient cancer cells ⬇️

scientific article published on 01 February 2012

Combination mTOR and IGF-1R Inhibition: Phase I Trial of Everolimus and Figitumumab in Patients with Advanced Sarcomas and Other Solid Tumors ⬇️

scientific article published on December 22, 2010

Cyclin-dependent kinases (cdks) and the DNA damage response: rationale for cdk inhibitor–chemotherapy combinations as an anticancer strategy for solid tumors ⬇️

scientific article published on November 1, 2010

Dependence on the MUC1-C Oncoprotein in Non–Small Cell Lung Cancer Cells ⬇️

scientific article published on March 18, 2011

Effect of aprepitant on the pharmacokinetics of the cyclin-dependent kinase inhibitor dinaciclib in patients with advanced malignancies ⬇️

scientific article published on 09 October 2012

Lack of food effect on single-dose pharmacokinetics of brivanib, and safety and efficacy following multiple doses in subjects with advanced or metastatic solid tumors ⬇️

scientific article published on April 3, 2011

Phase 1 Study of Molibresib (GSK525762), a Bromodomain and Extra-Terminal Domain Protein Inhibitor, in NUT Carcinoma and Other Solid Tumors

scientific article published on 06 November 2019

Phase I Dose-Escalation Study of Afatinib, An ErbB Family Blocker, Plus Docetaxel in Patients with Advanced Cancer ⬇️

scientific article published on February 1, 2013

Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of ENMD-2076, a Novel Angiogenic and Aurora Kinase Inhibitor,in Patients with Advanced Solid Tumors ⬇️

scientific article published on 03 December 2010

Phase I Studies of CBP501, a G2 Checkpoint Abrogator, as Monotherapy and in Combination with Cisplatin in Patients with Advanced Solid Tumors ⬇️

scientific article published on January 10, 2011

Phase I Study of RO4929097, a Gamma Secretase Inhibitor of Notch Signaling, in Patients With Refractory Metastatic or Locally Advanced Solid Tumors ⬇️

scientific article published on April 23, 2012

Poly(ADP-ribose) polymerase inhibitors as cancer therapy ⬇️

scientific article published on June 1, 2013

The Neuroblastoma-Associated F1174L ALK Mutation Causes Resistance to an ALK Kinase Inhibitor in ALK-Translocated Cancers ⬇️

scientific article published on October 28, 2010

The effect of food on the bioavailability of panobinostat, an orally active pan-histone deacetylase inhibitor, in patients with advanced cancer ⬇️

scientific article published on November 6, 2011

p16INK4A Participates in a G1 Arrest Checkpoint in Response to DNA Damage ⬇️

scientific article published on January 1, 1998

List of works by Geoffrey I Shapiro