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List of works by Ja-Lok Ku

A TP53-truncating germline mutation (E287X) in a family with characteristics of both hereditary diffuse gastric cancer and Li-Fraumeni syndrome

scientific article published on 10 September 2004

A functional polymorphism (-347 G-->GA) in the E-cadherin gene is associated with colorectal cancer

scientific article

A long non-coding RNA snaR contributes to 5-fluorouracil resistance in human colon cancer cells

scientific article

Acclimation to ultraviolet irradiation affects UV-B sensitivity of Daphnia magna to several environmental toxicants

scientific article published in December 2009

Alpha-tocopheryl succinate, in contrast to alpha-tocopherol and alpha-tocopheryl acetate, inhibits prostaglandin E2 production in human lung epithelial cells

scientific article

Antitumor effect of a WEE1 inhibitor and potentiation of olaparib sensitivity by DNA damage response modulation in triple-negative breast cancer

scientific article published on 18 June 2020

Antitumor effects of calgranulin B internalized in human colon cancer cells

scientific article published on 27 February 2016

Biallelic mutations in ABCB1 display recurrent reversible encephalopathy

scientific article published on 05 July 2020

Biology of SNU cell lines

scientific article published on 28 February 2005

CD133 and CD133-regulated nucleophosmin linked to 5-fluorouracil susceptibility in human colon cancer cell line SW620.

scientific article published on 16 December 2013

CD133-regulated nucleophosmin expression in human colon cancer cells

scientific article published on 11 February 2014

Clinicopathological Features and Type of Surgery for Lynch Syndrome: Changes during the Past Two Decades

scientific article published on 26 May 2015

Clonal History and Genetic Predictors of Transformation Into Small-Cell Carcinomas From Lung Adenocarcinomas

scientific article published on 12 May 2017

Correlation between the promoter methylation status of ATP-binding cassette sub-family G member 2 and drug sensitivity in colorectal cancer cell lines

scientific article published on 21 October 2015

Decreased pyruvate kinase M2 activity linked to cisplatin resistance in human gastric carcinoma cell lines

scientific article

Development and applications of a beta-catenin oligonucleotide microarray: beta-catenin mutations are dominantly found in the proximal colon cancers with microsatellite instability.

scientific article published in August 2003

Effects of granulocyte-colony stimulating factor and the expression of its receptor on various malignant cells ⬇️

scientific article published on September 25, 2012

Establishment and Characterization of 10 Human Pancreatic Cancer Cell Lines Including a HER2 Overexpressed Cell Line

scientific article published on 01 November 2019

Establishment and Characterization of Paired Primary and Peritoneal Seeding Human Colorectal Cancer Cell Lines: Identification of Genes That Mediate Metastatic Potential

article

Establishment and characterization of 13 human colorectal carcinoma cell lines: mutations of genes and expressions of drug-sensitivity genes and cancer stem cell markers

scientific article

Establishment and characterization of 18 human colorectal cancer cell lines

scientific article published on 22 April 2020

Establishment and characterization of cell lines from three human thyroid carcinomas: responses to all-trans-retinoic acid and mutations in the BRAF gene

scientific article published on 28 November 2006

Establishment and characterization of four human hepatocellular carcinoma cell lines containing hepatitis B virus DNA

scientific article

Establishment and characterization of four human pancreatic carcinoma cell lines. Genetic alterations in the TGFBR2 gene but not in the MADH4 gene

scientific article

Establishment and characterization of patient-derived xenograft models of gastrointestinal stromal tumor resistant to standard tyrosine kinase inhibitors.

scientific article published on 11 September 2017

Establishment and characterization of seven human breast cancer cell lines including two triple-negative cell lines

scientific article published on 18 October 2013

Establishment and characterization of six human gastric carcinoma cell lines, including one naturally infected with Epstein-Barr virus ⬇️

scientific article published on February 24, 2012

Establishment and characterization of six human lung cancer cell lines: EGFR, p53 gene mutations and expressions of drug sensitivity genes ⬇️

scientific article published on February 2, 2011

Exosomal miR-193a and let-7g accelerate cancer progression on primary colorectal cancer and paired peritoneal metastatic cancer

scientific article published on 19 December 2020

FAIM2, as a novel diagnostic maker and a potential therapeutic target for small-cell lung cancer and atypical carcinoid

scientific article published on 28 September 2016

Genetic alterations of the TGF-beta signaling pathway in colorectal cancer cell lines: a novel mutation in Smad3 associated with the inactivation of TGF-beta-induced transcriptional activation

scientific article published on 7 July 2006

Germline mutations in MLH1, MSH2 and MSH6 in Korean hereditary non-polyposis colorectal cancer families.

scientific article

Glutathione S-transferase M1 associated with cancer occurrence in Korean HNPCC families carrying the hMLH1/hMSH2 mutation

scientific article

Hereditary nonpolyposis colorectal cancer in endometrial cancer patients.

scientific article published in March 2008

Heterogeneity of genetic changes associated with acquired crizotinib resistance in ALK-rearranged lung cancer.

scientific article

Hydroxymethylglutaryl-Coenzyme A Synthase 2 Expression Is Associated With Chemoradiotherapy Responses in Colorectal Cancer ⬇️

scientific article published on June 1, 2012

Identification of a Novel Fusion Gene, FAM174A-WWC1, in Early-Onset Colorectal Cancer: Establishment and Characterization of Four Human Cancer Cell Lines from Early-Onset Colorectal Cancers

scientific article published on 20 June 2019

Identification of genes inducing resistance to ionizing radiation in human rectal cancer cell lines: re-sensitization of radio-resistant rectal cancer cells through down regulating NDRG1.

scientific article

Identification of genes with differential expression in acquired drug-resistant gastric cancer cells using high-density oligonucleotide microarrays

scientific article published on January 2004

Identification of novel cellular targets in biliary tract cancers using global gene expression technology

scientific article published on July 2003

Improving gastric cancer preclinical studies using diverse in vitro and in vivo model systems

scientific article

Induction of LGR5 by H2O2 treatment is associated with cell proliferation via the JNK signaling pathway in colon cancer cells ⬇️

scientific article published on August 22, 2012

Interleukin-7 Contributes to the Invasiveness of Prostate Cancer Cells by Promoting Epithelial-Mesenchymal Transition

scientific article published on 06 May 2019

Isolation and culture of colon cancer cell lines.

scientific article published on January 2004

Isolation and culture of renal cancer cell lines

scientific article published on January 2004

Maternal exposures to persistent organic pollutants are associated with DNA methylation of thyroid hormone-related genes in placenta differently by infant sex

scientific article published on 01 July 2019

Metformin increases chemo-sensitivity via gene downregulation encoding DNA replication proteins in 5-Fu resistant colorectal cancer cells

scientific article published on 11 May 2017

Methylation-specific PCR.

scientific article published on January 2011

Microsatellite instability and mutations in DNA mismatch repair genes in sporadic colorectal cancers.

scientific article published in August 2003

Microsatellite instability testing in Korean patients with colorectal cancer ⬇️

scientific article published on September 1, 2012

Multifocal Organoid Capturing of Colon Cancer Reveals Pervasive Intratumoral Heterogenous Drug Responses

scientific article published on 17 December 2021

Mutational analysis of BRAF and K-ras in gastric cancers: absence of BRAF mutations in gastric cancers ⬇️

scientific article published on September 25, 2003

Oligonucleotide microarray-based mutation detection of the K-ras gene in colorectal cancers with use of competitive DNA hybridization.

scientific article

Penta-fluorophenol: a Smiles rearrangement-inspired cysteine-selective fluorescent probe for imaging of human glioblastoma

scientific article published on 11 May 2020

Preclinical Modeling of Osimertinib for NSCLC With EGFR Exon 20 Insertion Mutations

scientific article published on 17 May 2019

Prenatal exposure to persistent organic pollutants and methylation of LINE-1 and imprinted genes in placenta: A CHECK cohort study

scientific article published on 10 July 2018

Presence of CCK-A, B receptors and effect of gastrin and cholecystokinin on growth of pancreatobiliary cancer cell lines

scientific article

Prognostic significance of microsatellite instability in sporadic colorectal cancer.

scientific article

Promoter hypermethylation and loss of CD133 gene expression in colorectal cancers

scientific article

Promoter hypermethylation and silencing of CHFR mitotic stress checkpoint gene in human gastric cancers

scientific article

Promoter hypermethylation downregulates RUNX3 gene expression in colorectal cancer cell lines

scientific article

Promoter hypermethylation of the ADAM23 gene in colorectal cancer cell lines and cancer tissues

scientific article

Promoter hypomethylation and reactivation of MAGE-A1 and MAGE-A3 genes in colorectal cancer cell lines and cancer tissues

scientific article

RET oligonucleotide microarray for the detection of RET mutations in multiple endocrine neoplasia type 2 syndromes.

scientific article published in February 2002

Rationally designed redirection of natural killer cells anchoring a cytotoxic ligand for pancreatic cancer treatment

scientific article published on 16 July 2020

Resistance of colorectal cancer cells to radiation and 5-FU is associated with MELK expression ⬇️

scientific article published on July 22, 2011

Robust microsatellite instability (MSI) analysis by denaturing high-performance liquid chromatography (DHPLC).

scientific article published on 12 September 2003

Role of reactive oxygen species in the induction of apoptosis by alpha-tocopheryl succinate

scientific article published in November 2004

SORBS1 serves a metastatic role via suppression of AHNAK in colorectal cancer cell lines

scientific article published on 05 March 2020

Stromal cell-derived factor-1α and macrophage migration-inhibitory factor induce metastatic behavior in CXCR4-expressing colon cancer cells ⬇️

scientific article published on September 25, 2012

Subcellular progression of mesenchymal transition identified by two discrete synchronous cell lines derived from the same glioblastoma

scientific article published on 12 March 2022

Systematic approach identifies RHOA as a potential biomarker therapeutic target for Asian gastric cancer

scientific article published on 28 October 2016

Telomerase activity, expression of Bcl-2 and cell cycle regulation in doxorubicin resistant gastric carcinoma cell lines.

scientific article published on March 2003

The E-cadherin -347G->GA promoter polymorphism and its effect on transcriptional regulation.

scientific article

The role of novel fusion genes in human GIST cell lines derived from imatinib-resistant GIST patients: A therapeutic potential of fusion gene

scientific article published on 18 July 2020

Validation of Prediction Models for Mismatch Repair Gene Mutations in Koreans

scientific article published on 5 June 2015

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