List of works - Lewis Becker

A Simple Scalable Association Hypothesis Test Combining Gene-wide Evidence From Multiple Polymorphisms

scientific article published on March 2014

A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium

scientific journal article

A common variant in the CDKN2B gene on chromosome 9p21 protects against coronary artery disease in Americans of African ancestry.

scientific article

A common variant in the Von Willebrand factor gene is associated with multiple functional consequences.

scientific article

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

scientific article

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

scientific article

Age differences in periventricular and deep white matter lesions.

scientific article

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

scientific article

Effect of obesity on platelet reactivity and response to low-dose aspirin.

scientific article published in January 2010

Effect of white matter lesions on manual dexterity in healthy middle-aged persons

scientific article published on 10 April 2015

Ethnic-specific determinants of exercise capacity in a healthy high-risk population

scientific article published in June 2012

Extreme deep white matter hyperintensity volumes are associated with African American race

scientific article

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

scientific article published on 19 December 2016

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation

scientific article

Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.

scientific article

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

scientific journal article

Glucose levels in the normal range predict incident diabetes in families with premature coronary heart disease

scientific article published on 23 May 2006

Greater collagen-induced platelet aggregation following cyclooxygenase 1 inhibition predicts incident acute coronary syndromes

scientific article

Heritability of platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1

scientific article (publication date: 15 May 2007)

Hypertension Is Associated with White Matter Disruption in Apparently Healthy Middle-Aged Individuals

scientific article published on 15 November 2018

Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry

scientific article

Impact of a community-based multiple risk factor intervention on cardiovascular risk in black families with a history of premature coronary disease

scientific article published in March 2005

Incidence of coronary artery disease in siblings of patients with premature coronary artery disease: 10 years of follow-up.

scientific article

Independent metabolic syndrome variants predict new-onset coronary artery disease.

scientific article

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

scientific article published on 14 October 2020

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

scientific article

Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease

scientific article published on 10 May 2019

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.

scientific article published on 21 November 2016

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

scientific article (publication date: 17 September 2013)

Native platelet aggregation and response to aspirin in persons with the metabolic syndrome and its components

scientific article

Noncalcified coronary plaque volumes in healthy people with a family history of early onset coronary artery disease.

scientific article published on 27 February 2014

Platelet inhibition by aspirin 81 and 325 mg/day in men versus women without clinically apparent cardiovascular disease.

scientific article

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

scientific article

Relation of Plasma Lipoprotein(a) to Subclinical Coronary Plaque Volumes, Three-Vessel and Left Main Coronary Disease, and Severe Coronary Stenoses in Apparently Healthy African-Americans With a Family History of Early-Onset Coronary Artery Disease.

scientific article

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

scientific article published on 6 March 2019

Severity of inducible myocardial ischemia predicts incident acute coronary syndromes in asymptomatic individuals with a family history of premature coronary artery disease.

scientific article published on 12 November 2011

Sex differences in platelet reactivity and response to low-dose aspirin therapy

scientific article (publication date: 22 March 2006)

Silent myocardial ischaemia and long-term coronary artery disease outcomes in apparently healthy people from families with early-onset ischaemic heart disease

scientific article published on 23 July 2011

Silent small-vessel cerebrovascular disease and silent myocardial ischemia in families with premature coronary disease

scientific article published on 28 April 2009

The association of brachial artery diameter with noncalcified coronary plaque burden in apparently healthy individuals

scientific article published on December 2013

The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans

scientific article

The robustness of generalized estimating equations for association tests in extended family data

scientific article

Trans-ethnic meta-analysis of white blood cell phenotypes

scientific article

Type 2 Diabetes Modifies the Association of CAD Genomic Risk Variants With Subclinical Atherosclerosis

scientific article published in December 2023

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

scientific article published on 23 December 2019

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

scientific article

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

scientific article

List of works by Lewis Becker

A Simple Scalable Association Hypothesis Test Combining Gene-wide Evidence From Multiple Polymorphisms

A bivariate genome-wide approach to metabolic syndrome: STAMPEED consortium

A common variant in the CDKN2B gene on chromosome 9p21 protects against coronary artery disease in Americans of African ancestry.

A common variant in the Von Willebrand factor gene is associated with multiple functional consequences.

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

Age differences in periventricular and deep white matter lesions.

Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

Effect of obesity on platelet reactivity and response to low-dose aspirin.

Effect of white matter lesions on manual dexterity in healthy middle-aged persons

Ethnic-specific determinants of exercise capacity in a healthy high-risk population

Extreme deep white matter hyperintensity volumes are associated with African American race

Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation

Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2.

Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm

Glucose levels in the normal range predict incident diabetes in families with premature coronary heart disease

Greater collagen-induced platelet aggregation following cyclooxygenase 1 inhibition predicts incident acute coronary syndromes

Heritability of platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1

Hypertension Is Associated with White Matter Disruption in Apparently Healthy Middle-Aged Individuals

Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry

Impact of a community-based multiple risk factor intervention on cardiovascular risk in black families with a history of premature coronary disease

Incidence of coronary artery disease in siblings of patients with premature coronary artery disease: 10 years of follow-up.

Independent metabolic syndrome variants predict new-onset coronary artery disease.

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies

Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease

Multiethnic Exome-Wide Association Study of Subclinical Atherosclerosis.

Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease

Native platelet aggregation and response to aspirin in persons with the metabolic syndrome and its components

Noncalcified coronary plaque volumes in healthy people with a family history of early onset coronary artery disease.

Platelet inhibition by aspirin 81 and 325 mg/day in men versus women without clinically apparent cardiovascular disease.

Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals

Relation of Plasma Lipoprotein(a) to Subclinical Coronary Plaque Volumes, Three-Vessel and Left Main Coronary Disease, and Severe Coronary Stenoses in Apparently Healthy African-Americans With a Family History of Early-Onset Coronary Artery Disease.

Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program

Severity of inducible myocardial ischemia predicts incident acute coronary syndromes in asymptomatic individuals with a family history of premature coronary artery disease.

Sex differences in platelet reactivity and response to low-dose aspirin therapy

Silent myocardial ischaemia and long-term coronary artery disease outcomes in apparently healthy people from families with early-onset ischaemic heart disease

Silent small-vessel cerebrovascular disease and silent myocardial ischemia in families with premature coronary disease

The association of brachial artery diameter with noncalcified coronary plaque burden in apparently healthy individuals

The impact of FADS genetic variants on ω6 polyunsaturated fatty acid metabolism in African Americans

The robustness of generalized estimating equations for association tests in extended family data

Trans-ethnic meta-analysis of white blood cell phenotypes

Type 2 Diabetes Modifies the Association of CAD Genomic Risk Variants With Subclinical Atherosclerosis

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis