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List of works by Brian D Marsden

3,5-dimethylisoxazoles act as acetyl-lysine-mimetic bromodomain ligands

scientific article

A Multi-Crystal Method for Extracting Obscured Signal from Crystallographic Electron Density

article published in 2016

A genetics-led approach defines the drug target landscape of 30 immune-related traits

scientific article published on 28 June 2019

A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density

scientific article (publication date: 24 April 2017)

A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP(2), an atypical bromodomain† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c5sc03115j.

scientific article published on 22 December 2015

Antibody Status and Incidence of SARS-CoV-2 Infection in Health Care Workers

scientific article published on 23 December 2020

Decreased blood vessel density and endothelial cell subset dynamics during ageing of the endocrine system

scientific article published on 20 November 2020

Differential occupational risks to healthcare workers from SARS-CoV-2 observed during a prospective observational study

scientific article published on 21 August 2020

Identification of a Chemical Probe for Bromo and Extra C-Terminal Bromodomain Inhibition through Optimization of a Fragment-Derived Hit

scientific article

Partial-occupancy binders identified by the Pan-Dataset Density Analysis method offer new chemical opportunities and reveal cryptic binding sites

scientific article published on 28 February 2017

SARS-CoV-2 antibody prevalence, titres and neutralising activity in an antenatal cohort, United Kingdom, 14 April to 15 June 2020

scientific article published on 01 October 2020

Structural basis for Cul3 protein assembly with the BTB-Kelch family of E3 ubiquitin ligases

scientific article published on 27 September 2013

The XChemExplorer graphical workflow tool for routine or large-scale protein-ligand structure determination.

scientific article

The duration, dynamics and determinants of SARS-CoV-2 antibody responses in individual healthcare workers

scientific article published on 06 January 2021

[1,2,4]triazolo[4,3-a]phthalazines: inhibitors of diverse bromodomains

scientific article

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