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List of works by Roman A Blaheta

Acetylation of histone H3 prevents resistance development caused by chronic mTOR inhibition in renal cell carcinoma cells ⬇️

scientific article published on May 8, 2012

Acquired resistance to temsirolimus is associated with integrin α7 driven chemotactic activity of renal cell carcinoma in vitro.

scientific article

Activated protein C downregulates p38 mitogen-activated protein kinase and improves clinical parameters in an in-vivo model of septic shock.

scientific article published in November 2007

Altered expression of beta1 integrins in renal carcinoma cell lines exposed to the differentiation inducer valproic acid.

scientific article published on August 2006

Amygdalin Modulates Prostate Cancer Cell Adhesion and Migration In Vitro

scientific article published on 12 July 2019

Amygdalin blocks bladder cancer cell growth in vitro by diminishing cyclin A and cdk2

scientific article

Amygdalin blocks the in vitro adhesion and invasion of renal cell carcinoma cells by an integrin-dependent mechanism

scientific article published on 8 January 2016

Amygdalin delays cell cycle progression and blocks growth of prostate cancer cells in vitro

scientific article published on 28 January 2016

Amygdalin influences bladder cancer cell adhesion and invasion in vitro

scientific article

Amygdalin inhibits the growth of renal cell carcinoma cells in vitro

scientific article published on 21 December 2015

Amygdalin, quackery or cure?

scientific article published on 17 February 2016

An endogenous inhibitor of angiogenesis derived from a transitional cell carcinoma: clipped beta2-glycoprotein-I.

scientific article published on 7 September 2006

Angiogenesis inhibition by angiostatin, endostatin and TNP-470 prevents cyclophosphamide induced cystitis

scientific article

Anti-tumor mechanisms of valproate: a novel role for an old drug

scientific article

Association of intravesical tumor location with metastases to the pelvic lymph nodes in transitional cell cancer of the bladder

scientific article published on 01 April 2010

Autocrine stimulation of human hepatocytes triggers late DNA synthesis and stabilizes long-term differentiation in vitro.

scientific article

Autophagy-associated proteins BAG3 and p62 in testicular cancer.

scientific article published on 22 December 2015

Binding of gastrointestinal tumor cells to endothelial E- and P-selectin adhesion receptors leads to transient down-regulation of sLeX ligands in vitro

scientific article

Bioguided identification of daucosterol, a compound that contributes to the cytotoxicity effects of Crateva adansonii DC (capparaceae) to prostate cancer cells

scientific article published on 24 September 2019

Bladder Cancer Metastasis Induced by Chronic Everolimus Application Can Be Counteracted by Sulforaphane In Vitro

scientific article published on 04 August 2020

Blocking integrin β1 decreases adhesion in chemoresistant urothelial cancer cell lines.

scientific article published on 4 September 2017

CCL2 Chemokine as a Potential Biomarker for Prostate Cancer: A Pilot Study

scientific article published on 13 October 2014

CCL2 promotes integrin-mediated adhesion of prostate cancer cells in vitro

scientific article published on 2 September 2014

CXC chemokine mRNA expression as a potential diagnostic tool in prostate cancer

scientific article published on 01 March 2008

CXCR4 chemokine receptor engagement modifies integrin dependent adhesion of renal carcinoma cells

scientific article published on 10 July 2007

CXCR4 chemokine receptor mediates prostate tumor cell adhesion through alpha5 and beta3 integrins

scientific article published on April 2006

Cardiac Surgery With Extracorporeal Circulation: Neutrophil Transendothelial Migration Is Mediated by β1 Integrin (CD29) in the Presence of TNF-Alpha

scientific article published on 01 September 2004

Chemokines involved in tumor promotion and dissemination in patients with renal cell cancer ⬇️

scientific article published on 01 January 2011

Chemoresistance induces enhanced adhesion and transendothelial penetration of neuroblastoma cells by down-regulating NCAM surface expression

scientific article published on 21 December 2006

Chemoresistance is associated with increased cytoprotective autophagy and diminished apoptosis in bladder cancer cells treated with the BH3 mimetic (-)-Gossypol (AT-101)

scientific article published on 7 April 2015

Chronic Sulforaphane Administration Inhibits Resistance to the mTOR-Inhibitor Everolimus in Bladder Cancer Cells

scientific article published on 04 June 2020

Chronic Sulforaphane Application Does Not Induce Resistance in Renal Cell Carcinoma Cells

scientific article published on 01 November 2018

Clinical relevance of maspin expression in bladder cancer

scientific article published on 11 July 2006

Combined targeting of the VEGFr/EGFr and the mammalian target of rapamycin (mTOR) signaling pathway delays cell cycle progression and alters adhesion behavior of prostate carcinoma cells ⬇️

scientific article published on November 30, 2010

Combining the receptor tyrosine kinase inhibitor AEE788 and the mammalian target of rapamycin (mTOR) inhibitor RAD001 strongly inhibits adhesion and growth of renal cell carcinoma cells

scientific article

Controlled and reversible induction of differentiation and activation of adult human hepatocytes by a biphasic culture technique

scientific article published on April 2005

Correction: Renal cell carcinoma alters endothelial receptor expression responsible for leukocyte adhesion

scientific article published on January 2017

Critical analysis of simultaneous blockage of histone deacetylase and multiple receptor tyrosine kinase in the treatment of prostate cancer ⬇️

scientific article published on October 15, 2010

Cross-communication between histone H3 and H4 acetylation and Akt-mTOR signalling in prostate cancer cells

scientific article published on 30 April 2014

Curcumin-A Viable Agent for Better Bladder Cancer Treatment

scientific article published on 26 May 2020

Cyanide and lactate levels in patients during chronic oral amygdalin intake followed by intravenous amygdalin administration

scientific article published on 06 March 2019

Cyr61/CCN1 affects the integrin-mediated migration of prostate cancer cells (PC-3) in vitro

scientific article published on January 1, 2013

Dasatinib enhances tumor growth in gemcitabine-resistant orthotopic bladder cancer xenografts

scientific article

De novo renal cell carcinoma of native and graft kidneys in renal transplant recipients ⬇️

scientific article published on November 10, 2010

Degradation of microvascular brain endothelial cell beta-catenin after co-culture with activated neutrophils from patients undergoing cardiac surgery with prolonged cardiopulmonary bypass

scientific article published in April 2005

Detection of early DJ-stent encrustation by sonographic twinkling-artifacts - a pilot study

scientific article

Development of resistance to vincristine and doxorubicin in neuroblastoma alters malignant properties and induces additional karyotype changes: a preclinical model

scientific article published in March 2003

Development of urological cancers in renal transplant recipients: 30-year experience at the Frankfurt Transplant Center

scientific article published on 01 November 2010

Effect of procurement-related organ lesions on renal transplant outcome

scientific article published on 03 February 2008

Effects of combined valproic acid and the epidermal growth factor/vascular endothelial growth factor receptor tyrosine kinase inhibitor AEE788 on renal cell carcinoma cell lines in vitro

scientific article

Elevation of circulating HLA DR(+) CD8(+) T-cells and correlation with chromium and cobalt concentrations 6 years after metal-on-metal hip arthroplasty.

scientific article published on 29 December 2010

Endothelial adhesion of synchronized gastric tumor cells changes during cell cycle transit and correlates with the expression level of CD44 splice variants.

scientific article published on October 2005

Ethanol-extracted Cameroonian propolis: Antiproliferative effects and potential mechanism of action in prostate cancer

scientific article published on 23 June 2020

Evaluation of TKTL1 as a biomarker in serum of prostate cancer patients

scientific article published on 30 June 2016

Evolving anticancer drug valproic acid: insights into the mechanism and clinical studies.

scientific article

Experimental imaging in orthotopic renal cell carcinoma xenograft models: comparative evaluation of high-resolution 3D ultrasonography, in-vivo micro-CT and 9.4T MRI.

scientific article published on 27 October 2017

Expression level of neural cell adhesion molecule (NCAM) inversely correlates with the ability of neuroblastoma cells to adhere to endothelium in vitro

scientific article published on May 2002

Expression of Foxp3 in Colorectal Cancer but Not in Treg Cells Correlates with Disease Progression in Patients with Colorectal Cancer ⬇️

scientific article published on January 30, 2013

Expression of angiogenesis inhibitors in human bladder cancer may explain rapid metastatic progression after radical cystectomy.

scientific article

Globalization in Urology: A Bibliographical Analysis of Cross-Continent Publication between 2002 and 2012.

scientific article published on 09 September 2015

Growth and Proliferation of Renal Cell Carcinoma Cells Is Blocked by Low Curcumin Concentrations Combined with Visible Light Irradiation ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2019

HDAC Inhibition Counteracts Metastatic Re-Activation of Prostate Cancer Cells Induced by Chronic mTOR Suppression

HDAC inhibition as a treatment concept to combat temsirolimus-resistant bladder cancer cells

scientific article published on 6 November 2017

HDAC inhibition delays cell cycle progression of human bladder cancer cells in vitro ⬇️

scientific article published on November 1, 2011

HDAC inhibition suppresses bladder cancer cell adhesion to collagen under flow conditions

scientific article published on 4 September 2013

HDAC-inhibition counteracts everolimus resistance in renal cell carcinoma in vitro by diminishing cdk2 and cyclin A.

scientific article

Human cytomegalovirus infection alters PC3 prostate carcinoma cell adhesion to endothelial cells and extracellular matrix

scientific article published on October 2006

Human cytomegalovirus infection of tumor cells downregulates NCAM (CD56): a novel mechanism for virus-induced tumor invasiveness

scientific article

I publish in I edit?--Do editorial board members of urologic journals preferentially publish their own scientific work?

scientific article

Impact of combined HDAC and mTOR inhibition on adhesion, migration and invasion of prostate cancer cells ⬇️

scientific article published on March 31, 2011

Increased malignant behavior in neuroblastoma cells with acquired multi-drug resistance does not depend on P-gp expression.

scientific article published on October 2005

Increased tumor vascularization is associated with the amount of immune competent PD-1 positive cells in testicular germ cell tumors.

scientific article published on 27 April 2018

Induction of differentiation and suppression of malignant phenotype of human neuroblastoma BE(2)-C cells by valproic acid: enhancement by combination with interferon-alpha

scientific article published on January 1, 2002

Influence of the HDAC Inhibitor Valproic Acid on the Growth and Proliferation of Temsirolimus-Resistant Prostate Cancer Cells In Vitro.

scientific article

Inhibitory effects of the HDAC inhibitor valproic acid on prostate cancer growth are enhanced by simultaneous application of the mTOR inhibitor RAD001 ⬇️

scientific article published on December 27, 2010

Intensified antineoplastic effect by combining an HDAC-inhibitor, an mTOR-inhibitor and low dosed interferon alpha in prostate cancer cells

scientific article

Interleukin-4, interleukin-10, and interleukin-1-receptor antagonist but not transforming growth factor-beta induce ramification and reduce adhesion molecule expression of rat microglial cells

scientific article

Knockdown of BAG3 sensitizes bladder cancer cells to treatment with the BH3 mimetic ABT-737.

scientific article

Latent heparanase facilitates VLA-4-mediated melanoma cell binding and emerges as a relevant target of heparin in the interference with metastatic progression

scientific article

Long-term production of major coagulation factors and inhibitors by primary human hepatocytes in vitro: perspectives for clinical application

scientific article published in August 2007

Low Dosed Curcumin Combined with Visible Light Exposure Inhibits Renal Cell Carcinoma Metastatic Behavior In Vitro

scientific article published on 28 January 2020

Low dosed interferon alpha augments the anti‐tumor potential of histone deacetylase inhibition on prostate cancer cell growth and invasion ⬇️

scientific article published on April 2, 2012

Maspin modulates adhesion of bladder carcinoma cells to vascular endothelium

scientific article published on 25 March 2010

Mechanisms behind Temsirolimus Resistance Causing Reactivated Growth and Invasive Behavior of Bladder Cancer Cells In Vitro

scientific article published on 04 June 2019

MicroRNA-145 targets the metalloprotease ADAM17 and is suppressed in renal cell carcinoma patients

scientific article published on February 2013

Modulation of adhesion and growth of colon and pancreatic cancer cells by the histone deacetylase inhibitor valproic acid

scientific article published in September 2008

Modulation of the CXC-chemokine expression profile on tumor cells by the immunosuppressive drug mycophenolate mofetil.

scientific article

Molecular analysis of sunitinib resistant renal cell carcinoma cells after sequential treatment with RAD001 (everolimus) or sorafenib

scientific article

Molecular targeting of prostate cancer cells by a triple drug combination down-regulates integrin driven adhesion processes, delays cell cycle progression and interferes with the cdk-cyclin axis ⬇️

scientific article published on August 25, 2011

Mycophenolate mofetil increases adhesion capacity of tumor cells in vitro

scientific article published on December 2003

Mycophenolate mofetil modulates adhesion receptors of the beta1 integrin family on tumor cells: impact on tumor recurrence and malignancy

scientific article

NOD1 and NOD2 of the innate immune system is differently expressed in human clear cell renal cell carcinoma, corresponding healthy renal tissue, its vasculature and primary isolated renal tubular epithelial cells

scientific article published on 22 March 2019

Phosphorylation of hepatocyte growth factor receptor and epidermal growth factor receptor of human hepatocytes can be maintained in a (3D) collagen sandwich culture system

scientific article published in August 2004

Plasmin-clipped beta(2)-glycoprotein-I inhibits endothelial cell growth by down-regulating cyclin A, B and D1 and up-regulating p21 and p27.

scientific article published in October 2010

Preservation of the synthetic and metabolic capacity of isolated human hepatocytes by coculture with human biliary epithelial cells

scientific article

Prostate tumor CXC-chemokine profile correlates with cell adhesion to endothelium and extracellular matrix

scientific article published on 02 November 2005

Publication of Original Research in Urologic Journals – A Neglected Orphan? ⬇️

scientific article published on December 19, 2012

Relevance of the natural HDAC inhibitor sulforaphane as a chemopreventive agent in urologic tumors

scientific article published on 17 July 2018

Relocalization of endothelial cell beta-catenin after coculture with activated neutrophils from patients undergoing cardiac surgery with cardiopulmonary bypass.

scientific article published in May 2004

Renal cell carcinoma alters endothelial receptor expression responsible for leukocyte adhesion.

scientific article published on March 2016

Resistance after chronic application of the HDAC-inhibitor valproic acid is associated with elevated Akt activation in renal cell carcinoma in vivo

scientific article

Resistance to nanoparticle albumin-bound paclitaxel is mediated by ABCB1 in urothelial cancer cells

scientific article

Resistance to the mTOR inhibitor temsirolimus alters adhesion and migration behavior of renal cell carcinoma cells through an integrin α5- and integrin β3-dependent mechanism

scientific article

Simvastatin modulates the adhesion and growth of hepatocellular carcinoma cells via decrease of integrin expression and ROCK

scientific article published on 28 December 2010

Strategy of robotic surgeons to exert public influence through Twitter

scientific article

Sulforaphane Reduces Prostate Cancer Cell Growth and Proliferation In Vitro by Modulating the Cdk-Cyclin Axis and Expression of the CD44 Variants 4, 5, and 7

scientific article published on 18 November 2020

Sulforaphane as an adjunctive to everolimus counteracts everolimus resistance in renal cancer cell lines

scientific article published on 31 January 2017

Sulforaphane inhibits proliferation and invasive activity of everolimus-resistant kidney cancer cells in vitro

scientific article

TLR7 and TLR8 expression increases tumor cell proliferation and promotes chemoresistance in human pancreatic cancer

scientific article

The Antitumor Effect of Curcumin in Urothelial Cancer Cells Is Enhanced by Light Exposure In Vitro

scientific article published on 11 March 2019

The Na+/H+ exchange inhibitor HOE642 prevents stress-induced epithelial barrier dysfunction

scientific article

The cdk1-cyclin B complex is involved in everolimus triggered resistance in the PC3 prostate cancer cell line ⬇️

scientific article published on September 3, 2011

The histone deacetylase inhibitor valproic acid alters growth properties of renal cell carcinoma in vitro and in vivo.

scientific article published on 24 July 2008

The prostate cancer blocking potential of the histone deacetylase inhibitor LBH589 is not enhanced by the multi receptor tyrosine kinase inhibitor TKI258 ⬇️

scientific article published on July 17, 2012

Transient down-regulation of beta1 integrin subtypes on kidney carcinoma cells is induced by mechanical contact with endothelial cell membranes

scientific article published on July 2007

Transitional Cell Carcinoma of the Native Urinary Tract After Kidney Transplantation: Recommendations Following a Long-Term Retrospective Analysis ⬇️

scientific article published on 01 June 2011

Tumor-endothelium cross talk blocks recruitment of neutrophils to endothelial cells: a novel mechanism of endothelial cell anergy

scientific article published on October 2009

Use of complementary and alternative medicine before and after organ removal due to urologic cancer

scientific article

Valproate and valproate-analogues: potent tools to fight against cancer.

scientific article

Valproate inhibits colon cancer growth through cell cycle modification in vivo and in vitro

scientific article

Valproic acid blocks adhesion of renal cell carcinoma cells to endothelium and extracellular matrix

scientific article published in August 2009

Valproic acid inhibits angiogenesis in vitro and in vivo

scientific article published in March 2004

Valproic acid modulates NCAM polysialylation and polysialyltransferase mRNA expression in human tumor cells.

scientific article

c-Met responsiveness of isolated hepatocytes evaluated in an in vitro de-differentiation model.

scientific article published in March 2006

mTOR inhibition reduces growth and adhesion of hepatocellular carcinoma cells in vitro

scientific article

miR-21-3p is a positive regulator of L1CAM in several human carcinomas.

scientific article published on 19 August 2014

sE-cadherin is upregulated in serum of patients with renal cell carcinoma and promotes tumor cell dissemination in vitro

scientific article published on 18 April 2019

sE-cadherin serves as a diagnostic and predictive parameter in prostate cancer patients

scientific article published on 14 May 2015

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