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List of works by Graham R Moran

(4-Hydroxyphenyl)pyruvate dioxygenase from Streptomyces avermitilis: the basis for ordered substrate addition

scientific article (publication date: 25 February 2003)

4-Hydroxyphenylpyruvate dioxygenase

scientific article

4-Hydroxyphenylpyruvate dioxygenase and hydroxymandelate synthase: exemplars of the α-keto acid dependent oxygenases

scientific article

Accumulation of multiple intermediates in the catalytic cycle of (4-hydroxyphenyl)pyruvate dioxygenase from Streptomyces avermitilis

scientific article published in May 2005

Activation of α-keto acid-dependent dioxygenases: application of an {FeNO}7/{FeO2}8 methodology for characterizing the initial steps of O2 activation

scientific article published on 21 October 2011

An Open and Shut Case: The Interaction of Magnesium with MST Enzymes

scientific article

An improved method for the expression and purification of porcine dihydropyrimidine dehydrogenase

scientific article published on 21 February 2020

Anaerobic methods for the transient-state study of flavoproteins: The use of specialized glassware to define the concentration of dioxygen

scientific article published on 10 April 2019

Bacterial Renalase: Structure and Kinetics of an Enzyme with 2- and 6-Dihydro-β-NAD(P) Oxidase Activity from Pseudomonas phaseolicola

scientific article

Burkholderia cenocepacia C5424 produces a pigment with antioxidant properties using a homogentisate intermediate.

scientific article

CD and MCD studies of the non-heme ferrous active site in (4-hydroxyphenyl)pyruvate dioxygenase: correlation between oxygen activation in the extradiol and alpha-KG-dependent dioxygenases

scientific article published in April 2004

Catalytic, noncatalytic, and inhibitory phenomena: kinetic analysis of (4-hydroxyphenyl)pyruvate dioxygenase from Arabidopsis thaliana

scientific article published in May 2006

Correction to "Transient-State Analysis of Human Isocitrate Dehydrogenase I: Accounting for the Interconversion of Active and Non-Active Conformational States"

scientific article published on 26 August 2020

Evidence for the Mechanism of Hydroxylation by 4-Hydroxyphenylpyruvate Dioxygenase and Hydroxymandelate Synthase from Intermediate Partitioning in Active Site Variants

article

Form follows function: structural and catalytic variation in the class a flavoprotein monooxygenases

scientific article published on 23 November 2012

Heterologous expression and purification of kynurenine-3-monooxygenase from Pseudomonas fluorescens strain 17400.

scientific article published on 11 August 2006

Hydrogen movements in the oxidative half-reaction of kynurenine 3-monooxygenase from Pseudomonas fluorescens reveal the mechanism of hydroxylation

scientific article published on 17 July 2020

Interaction of (4-hydroxyphenyl)pyruvate dioxygenase with the specific inhibitor 2-[2-nitro-4-(trifluoromethyl)benzoyl]-1,3-cyclohexanedione

scientific article (publication date: 2 September 2003)

Intermediate partitioning kinetic isotope effects for the NIH shift of 4-hydroxyphenylpyruvate dioxygenase and the hydroxylation reaction of hydroxymandelate synthase reveal mechanistic complexity

scientific article published on 20 August 2013

Kinetic analysis of human homogentisate 1,2-dioxygenase

scientific article published in January 2004

Kinetics and equilibria of the reductive and oxidative half-reactions of human renalase with α-NADPH.

scientific article

Kynurenine 3-monooxygenase from Pseudomonas fluorescens: substrate-like inhibitors both stimulate flavin reduction and stabilize the flavin-peroxo intermediate yet result in the production of hydrogen peroxide

scientific article

Ligand binding phenomena that pertain to the metabolic function of renalase

scientific article published on 18 October 2016

Linking Inflammation and Parkinson Disease: Hypochlorous Acid Generates Parkinsonian Poisons

scientific article published on 29 March 2016

Linking Inflammation and Parkinson Disease: Hypochlorous Acid Generates Parkinsonian Poisons.

scientific article published in October 2016

Metabolic function for human renalase: oxidation of isomeric forms of β-NAD(P)H that are inhibitory to primary metabolism

scientific article

N5 Is the New C4a: Biochemical Functionalization of Reduced Flavins at the N5 Position

scientific article published on 30 October 2020

NfoR, Chromate Reductase or FMN reductase?

scientific article published on 04 September 2020

Plasmid Mutagenesis by PCR for High-Level Expression of Para-hydroxybenzoate Hydroxylase ⬇️

scientific article published on 01 April 1995

Product analysis and inhibition studies of a causative Asn to Ser variant of 4-hydroxyphenylpyruvate dioxygenase suggest a simple route to the treatment of Hawkinsinuria

scientific article published on August 2010

PvdF of pyoverdin biosynthesis is a structurally unique N10-formyltetrahydrofolate-dependent formyltransferase

scientific article published on 26 January 2019

Renalase does not catalyze the oxidation of catecholamines

scientific article published on 3 June 2015

Renalase is an α-NAD(P)H oxidase/anomerase

scientific article

Role of substrate positioning in the catalytic reaction of 4-hydroxyphenylpyruvate dioxygenase-A QM/MM Study.

scientific article published on 16 September 2014

Role of tryptophan hydroxylase phe313 in determining substrate specificity

scientific article published in April 2002

Shewanella oneidensis cytochrome c nitrite reductase (ccNiR) does not disproportionate hydroxylamine to ammonia and nitrite, despite a strongly favorable driving force

scientific article published on 28 March 2014

Spectroscopic and computational studies of NTBC bound to the non-heme iron enzyme (4-hydroxyphenyl)pyruvate dioxygenase: active site contributions to drug inhibition

scientific article

Spectroscopic and electronic structure studies of aromatic electrophilic attack and hydrogen-atom abstraction by non-heme iron enzymes

scholarly article

Spectroscopic and electronic structure studies of the role of active site interactions in the decarboxylation reaction of alpha-keto acid-dependent dioxygenases

scientific article published on 26 September 2006

Staphylopine and pseudopaline dehydrogenase from bacterial pathogens catalyze reversible reactions and produce stereospecific metallophores

scientific article published on 15 October 2019

Streptomyces wadayamensis MppP Is a Pyridoxal 5'-Phosphate-Dependent L-Arginine α-Deaminase, γ-Hydroxylase in the Enduracididine Biosynthetic Pathway

scientific article

Structural and Kinetic Analyses Reveal the Dual Inhibition Modes of Ornithine Aminotransferase by (1<i>S</i>,3<i>S</i>)-3-Amino-4-(hexafluoropropan-2-ylidenyl)-cyclopentane-1-carboxylic Acid (BCF<sub>3</sub>)

scientific article published on 14 December 2020

Structural and mechanistic comparisons of the metal-binding members of the vicinal oxygen chelate (VOC) superfamily

scientific article published on 04 July 2011

Structurally diverse dehydroshikimate dehydratase variants participate in microbial quinate catabolism

scientific article published on 5 October 2016

Structure of the ferrous form of (4-hydroxyphenyl)pyruvate dioxygenase from Streptomyces avermitilis in complex with the therapeutic herbicide, NTBC.

scientific article

The Interaction of Hydroxymandelate Synthase with the 4-Hydroxyphenylpyruvate Dioxygenase Inhibitor: NTBC

scientific article published on March 2008

The catalytic function of renalase: A decade of phantoms

scientific article published on 18 April 2015

The diverse and pervasive chemistries of the alpha-keto acid dependent enzymes

scientific article published on 13 April 2007

The enzyme: Renalase

scientific article

The rate-limiting catalytic steps of hydroxymandelate synthase from Amycolatopsis orientalis

scientific article published in March 2010

The three-his triad in Dke1: comparisons to the classical facial triad

scientific article

Transient State Analysis of Porcine Dihydropyrimidine Dehydrogenase Reveals Reductive Activation by NADPH

scientific article published on 09 June 2020

Transient-State Analysis of Human Isocitrate Dehydrogenase I: Accounting for the Interconversion of Active and Non-Active Conformational States

scientific article published on 10 September 2019

Two roads diverged: the structure of hydroxymandelate synthase from Amycolatopsis orientalis in complex with 4-hydroxymandelate

scientific article

We two alone will sing: the two-substrate alpha-keto acid-dependent oxygenases

scientific article published on 20 July 2009

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